UCSF

Leishmania Major (113 Compounds)

Swissprot:
Z50460
Stitch:
Z50460
UniProt:
Z50460
ChEMBL:
CHEMBL612879

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Functional ≤ 10μM 113 19 16 9
ADME/T ≤ 10μM 3 0 2 0

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 31
Z50420 Z50420 CHEMBL612851 Trypanosoma Brucei Brucei 17
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 15
Z50459 Z50459 CHEMBL367 Leishmania Donovani 10
Z50457 Z50457 CHEMBL612877 Leishmania Amazonensis 8
Z50466 Z50466 CHEMBL368 Trypanosoma Cruzi 7
Z50461 Z50461 CHEMBL612880 Leishmania Mexicana 6
Z103192 Z103192 CHEMBL1075362 Trypanosoma Evansi 5
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 5
Z50422 Z50422 CHEMBL612853 Entamoeba Histolytica 4
Z50426 Z50426 CHEMBL612856 Plasmodium Falciparum (isolate K1 / Thailand) 4
Z50458 Z50458 CHEMBL612878 Leishmania Braziliensis 4
Z101865 Z101865 CHEMBL612790 Leishmania Chagasi 3
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 3
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 3
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 3
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 2
CAC1D_RAT P27732 CHEMBL4132 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat 2
CAC1E_RAT Q07652 CHEMBL4115 Voltage-gated R-type Calcium Channel Alpha-1E Subunit, Rat 2
CAC1S_RAT Q02485 CHEMBL4108 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat 2
Z50417 Z50417 CHEMBL612848 Leishmania Infantum 2
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 2
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 2
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 2
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 2
Z80227 Z80227 CHEMBL614324 MCF7-ADR (Breast Carcinoma Cells) 2
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 2
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 2
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 2
Z81024 Z81024 CHEMBL396 NCI-H460 (Non-small Cell Lung Carcinoma) 2
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 2
CP2D6_HUMAN P10635 CHEMBL289 Cytochrome P450 2D6, Human 1
TOP1_HUMAN P11387 CHEMBL1781 DNA Topoisomerase I, Human 1
TOP1_MOUSE Q04750 CHEMBL2814 DNA Topoisomerase I, Mouse 1
TOP2A_HUMAN P11388 CHEMBL1806 DNA Topoisomerase II Alpha, Human 1
TOP2A_MOUSE Q01320 CHEMBL3586 DNA Topoisomerase II Alpha, Mouse 1
TOP2B_HUMAN Q02880 CHEMBL3396 DNA Topoisomerase II Beta, Human 1
TOP2B_MOUSE Q64511 CHEMBL5564 DNA Topoisomerase II Beta, Mouse 1
Z101870 Z101870 CHEMBL612793 Leishmania Guyanensis 1
Z103205 Z103205 CHEMBL1075390 A431 1
Z50038 Z50038 CHEMBL612328 Plasmodium Yoelii Yoelii 1
Z50339 Z50339 CHEMBL613064 Pneumocystis Carinii 1
Z50380 Z50380 CHEMBL613088 Mycobacterium Smegmatis 1
Z50418 Z50418 CHEMBL612849 Trypanosoma Brucei 1
Z50462 Z50462 CHEMBL612881 Leishmania Tropica 1
Z50467 Z50467 CHEMBL612884 Trichomonas Vaginalis 1
Z50468 Z50468 CHEMBL612652 Giardia Intestinalis 1
Z50473 Z50473 CHEMBL612653 Plasmodium Berghei 1
Z50594 Z50594 CHEMBL375 Mus Musculus 1
Z50717 Z50717 CHEMBL612241 Leishmania Sp. 1
Z50725 Z50725 CHEMBL612348 Trypanosoma Brucei Rhodesiense 1
Z80014 Z80014 CHEMBL614514 A204 (Rhabdomyosarcoma Cells) 1
Z80021 Z80021 CHEMBL614516 A498 (Renal Carcinoma Cells) 1
Z80025 Z80025 CHEMBL614519 ACHN (Renal Adenocarcinoma Cells) 1
Z80035 Z80035 CHEMBL381 B16 (Melanoma Cells) 1
Z80060 Z80060 CHEMBL614536 CAPAN-1 (Pancreatic Adenocarcinoma Cells) 1
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 1
Z80084 Z80084 CHEMBL614554 CEM-VLB (Vinblastine-resistant T-cell Leukemia Cells) 1
Z80085 Z80085 CHEMBL614030 CEM-VM1 (Etoposide-resistant T-cell Leukemia Cells) 1
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 1
Z80089 Z80089 CHEMBL614555 CHO-AA8 1
Z80115 Z80115 CHEMBL612702 DC3F 1
Z80117 Z80117 CHEMBL614283 DC3F/AD-II 1
Z80134 Z80134 CHEMBL614295 EVSA-T 1
Z80152 Z80152 CHEMBL613510 HCT-8 (Ileocecal Adenocarcinoma) 1
Z80188 Z80188 CHEMBL614590 KB 3-1 (Cervical Epithelial Carcinoma Cells) 1
Z80240 Z80240 CHEMBL614129 MDA-MB-361 1
Z80244 Z80244 CHEMBL614335 MDA-MB-468 (Breast Adenocarcinoma) 1
Z80254 Z80254 CHEMBL614343 MES-SA (Uterine Sarcoma Cells) 1
Z80255 Z80255 CHEMBL613827 MES-SA/DxS (Uterine Sarcoma Cells) 1
Z80285 Z80285 CHEMBL614177 MOLT-4 (Acute T-lymphoblastic Leukemia Cells) 1
Z80322 Z80322 CHEMBL614135 NCI-H358 (Lung Carcinama Cells) 1
Z80335 Z80335 CHEMBL614200 NHDF 1
Z80342 Z80342 CHEMBL612554 NSCLC (Non-small Cell Lung Carcinoma Cells) 1
Z80354 Z80354 CHEMBL614213 OVCAR-3 (Ovarian Adenocarcinoma Cells) 1
Z80364 Z80364 CHEMBL614218 P388/ADR (Lymphoma Cells) 1
Z80466 Z80466 CHEMBL614907 SF268 1
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 1
Z80485 Z80485 CHEMBL614919 SK-MEL-28 (Melanoma Cells) 1
Z80532 Z80532 CHEMBL614774 T-24 (Bladder Carcinoma Cells) 1
Z80571 Z80571 CHEMBL612797 UCLA P-3 1
Z80585 Z80585 CHEMBL613532 WALKER 1
Z80601 Z80601 CHEMBL614060 XRS6 1
Z80606 Z80606 CHEMBL612816 YOSHIDA (Sarcoma Cells) 1
Z80608 Z80608 CHEMBL614393 ZR-75-1 (Breast Carcinoma Cells) 1
Z80612 Z80612 CHEMBL612818 2008 (Ovarian Carcinoma Cells) 1
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 1
Z80819 Z80819 CHEMBL614484 J774.2 1
Z80846 Z80846 CHEMBL614493 F460pv8/eto Cell Line 1
Z80889 Z80889 CHEMBL614803 NCI-H322M (Non-small Cell Lung Carcinoma Cells) 1
Z80896 Z80896 CHEMBL614805 NCI-H69 (Small Cell Lung Carcinoma Cells) 1
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 1
Z80957 Z80957 CHEMBL614734 HMEC (Microvascular Endothelial Cells) 1
Z81017 Z81017 CHEMBL614647 WiDr (Colon Adenocarcinoma Cells) 1
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 1
Z81034 Z81034 CHEMBL614004 A2780 (Ovarian Carcinoma Cells) 1
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 1
Z81133 Z81133 CHEMBL614000 L1210 (1565) 1
Z81135 Z81135 CHEMBL614793 L6 (Skeletal Muscle Myoblast Cells) 1
Z81138 Z81138 CHEMBL613872 ScN2a (Scrapie-infected Neuroblastoma Cells) 1
Z81159 Z81159 CHEMBL614087 Lewis Cell Line 1
Z81160 Z81160 CHEMBL614088 Lewis Lung Carcinoma Cell Line 1
Z81164 Z81164 CHEMBL614091 LL Cell Line 1
Z81167 Z81167 CHEMBL614093 LLTC Cell Line 1
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 1
Z81227 Z81227 CHEMBL614116 M-19 Cell Line 1
Z81244 Z81244 CHEMBL614123 J774 (Macrophage Cells) 1
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 1
Z81280 Z81280 CHEMBL614740 NCI-H226 (Non-small Cell Lung Carcinoma Cells) 1
Z81284 Z81284 CHEMBL614999 NCI-H647 1
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 1