UCSF

A498 (Renal Carcinoma Cells) (50 Compounds)

Swissprot:
Z80021
Stitch:
Z80021
UniProt:
Z80021
ChEMBL:
CHEMBL614516

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Functional ≤ 10μM 50 8 9 6
ADME/T ≤ 10μM 0 0 0 0

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 26
Z80214 Z80214 CHEMBL614317 M14 (Melanoma Cells) 25
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 23
Z81280 Z81280 CHEMBL614740 NCI-H226 (Non-small Cell Lung Carcinoma Cells) 21
Z81283 Z81283 CHEMBL614387 NCI-H522 (Non-small Cell Lung Carcinoma Cells) 21
Z80099 Z80099 CHEMBL614561 COLO 205 (Colon Adenocarcinoma Cells) 20
Z81246 Z81246 CHEMBL614078 MDA-N (Breast Carcinoma Cells) 20
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 19
Z80482 Z80482 CHEMBL614917 SK-MEL-2 (Melanoma Cells) 18
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 18
Z80570 Z80570 CHEMBL614610 UACC-62 (Melanoma Cells) 17
Z81024 Z81024 CHEMBL396 NCI-H460 (Non-small Cell Lung Carcinoma) 15
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 13
Z80640 Z80640 CHEMBL613102 786-0 (Renal Carcinoma Cells) 13
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 12
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 12
Z81335 Z81335 CHEMBL612263 HCT-15 (Colon Adenocarcinoma Cells) 12
Z80125 Z80125 CHEMBL613508 DU-145 (Prostate Carcinoma) 11
Z80485 Z80485 CHEMBL614919 SK-MEL-28 (Melanoma Cells) 11
Z80025 Z80025 CHEMBL614519 ACHN (Renal Adenocarcinoma Cells) 10
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 10
Z80438 Z80438 CHEMBL614886 RXF 393 (Renal Carcinoma Cells) 10
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 10
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 9
Z81248 Z81248 CHEMBL614021 Malme-3M (Melanoma Cells) 9
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 9
Z80493 Z80493 CHEMBL614925 SK-OV-3 (Ovarian Carcinoma Cells) 8
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 7
Z80354 Z80354 CHEMBL614213 OVCAR-3 (Ovarian Adenocarcinoma Cells) 7
Z80574 Z80574 CHEMBL612799 UMUC3 7
Z81184 Z81184 CHEMBL614096 LOX IMVI (Melanoma Cells) 7
Z80120 Z80120 CHEMBL614285 DLD-1 (Colon Adenocarcinoma Cells) 6
Z80192 Z80192 CHEMBL614709 KM12 (Colon Adenocarcinoma Cells) 6
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 6
Z80254 Z80254 CHEMBL614343 MES-SA (Uterine Sarcoma Cells) 6
Z80285 Z80285 CHEMBL614177 MOLT-4 (Acute T-lymphoblastic Leukemia Cells) 6
Z80532 Z80532 CHEMBL614774 T-24 (Bladder Carcinoma Cells) 6
Z80889 Z80889 CHEMBL614803 NCI-H322M (Non-small Cell Lung Carcinoma Cells) 6
Z81017 Z81017 CHEMBL614647 WiDr (Colon Adenocarcinoma Cells) 6
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 6
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 5
Z80164 Z80164 CHEMBL614580 HT-1080 (Fibrosarcoma Cells) 5
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 5
Z80488 Z80488 CHEMBL614922 SK-MEL-5 (Melanoma Cells) 5
Z80559 Z80559 CHEMBL615021 U251 5
Z80563 Z80563 CHEMBL615025 U-373 MG ( Glioblastoma Cells) 5
Z80565 Z80565 CHEMBL614247 U-87 MG (Glioblastoma Cells) 5
Z80608 Z80608 CHEMBL614393 ZR-75-1 (Breast Carcinoma Cells) 5
Z80661 Z80661 CHEMBL614567 A704 (Renal Carcinoma Cells) 5
Z80991 Z80991 CHEMBL614645 Hs-578T (Breast Carcinoma Cells) 5
Z80014 Z80014 CHEMBL614514 A204 (Rhabdomyosarcoma Cells) 4
Z80377 Z80377 CHEMBL614228 PaCa2 4
Z80433 Z80433 CHEMBL614882 RPMI-8226 (Multiple Myeloma Cells) 4
Z80466 Z80466 CHEMBL614907 SF268 4
Z80468 Z80468 CHEMBL614908 SF-295 (Glioblastoma Cells) 4
Z80498 Z80498 CHEMBL614054 SN12C (Renal Carcinoma Cells) 4
Z80560 Z80560 CHEMBL615022 U-251 (Glioma Cells) 4
Z80568 Z80568 CHEMBL612796 UACC-257 (Melanoma Cells) 4
Z81054 Z81054 CHEMBL613977 SF-268 (Glioblastoma Cells) 4
Z81201 Z81201 CHEMBL614643 HOP-62 (Non-small Cell Lung Carcinoma Cells) 4
Z81281 Z81281 CHEMBL614997 NCI-H23 (Non-small Cell Lung Carcinoma Cells) 4
Z81322 Z81322 CHEMBL614860 SF-539 (Glioblastoma Cells) 4
Z80019 Z80019 CHEMBL614515 A-427 (Lung Carcinoma Cells) 3
Z80035 Z80035 CHEMBL381 B16 (Melanoma Cells) 3
Z80045 Z80045 CHEMBL613870 BT-20 (Breast Carcinoma Cells) 3
Z80048 Z80048 CHEMBL614530 BXPC-3 (Pancreatic Adenocarcinoma Cells) 3
Z80056 Z80056 CHEMBL613852 CAKI-2 (Renal Carcinoma Cells) 3
Z80086 Z80086 CHEMBL613506 CFPAC-1 (Pancreatic Carcinoma Cells) 3
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 3
Z80188 Z80188 CHEMBL614590 KB 3-1 (Cervical Epithelial Carcinoma Cells) 3
Z80227 Z80227 CHEMBL614324 MCF7-ADR (Breast Carcinoma Cells) 3
Z80240 Z80240 CHEMBL614129 MDA-MB-361 3
Z80244 Z80244 CHEMBL614335 MDA-MB-468 (Breast Adenocarcinoma) 3
Z80255 Z80255 CHEMBL613827 MES-SA/DxS (Uterine Sarcoma Cells) 3
Z80269 Z80269 CHEMBL614354 MKN-45 (Gastric Adenocarcinoma Cells) 3
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 3
Z80364 Z80364 CHEMBL614218 P388/ADR (Lymphoma Cells) 3
Z80381 Z80381 CHEMBL614139 PANC-1 (Pancreatic Carcinoma Cells) 3
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 3
Z80539 Z80539 CHEMBL614775 T98G (Glioblastoma Cells) 3
Z80697 Z80697 CHEMBL614279 Bel-7402 (Hepatoma Cells) 3
Z80711 Z80711 CHEMBL613829 NCI/ADR-RES (Breast Carcinoma Cells) 3
Z80800 Z80800 CHEMBL614725 MIA PaCa-2 (Pancreatic Carcinoma Cells) 3
Z80847 Z80847 CHEMBL612250 FaDu (Pharyngeal Carcinoma Cells) 3
Z80891 Z80891 CHEMBL614804 H4 (Hepatoma Cells) 3
Z80896 Z80896 CHEMBL614805 NCI-H69 (Small Cell Lung Carcinoma Cells) 3
Z80996 Z80996 CHEMBL614836 HT1197 (Bladder Carcinoma Cells) 3
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 3
Z81034 Z81034 CHEMBL614004 A2780 (Ovarian Carcinoma Cells) 3
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 3
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 3
Z81133 Z81133 CHEMBL614000 L1210 (1565) 3
TOP1_HUMAN P11387 CHEMBL1781 DNA Topoisomerase I, Human 2
TOP1_MOUSE Q04750 CHEMBL2814 DNA Topoisomerase I, Mouse 2
TOP2A_HUMAN P11388 CHEMBL1806 DNA Topoisomerase II Alpha, Human 2
TOP2A_MOUSE Q01320 CHEMBL3586 DNA Topoisomerase II Alpha, Mouse 2
TOP2B_HUMAN Q02880 CHEMBL3396 DNA Topoisomerase II Beta, Human 2
TOP2B_MOUSE Q64511 CHEMBL5564 DNA Topoisomerase II Beta, Mouse 2
Z103203 Z103203 CHEMBL1075388 A375 2
Z103205 Z103205 CHEMBL1075390 A431 2
Z103219 Z103219 CHEMBL1075404 Ca9-22 2
Z50347 Z50347 CHEMBL361 Saccharomyces Cerevisiae 2
Z50424 Z50424 CHEMBL612855 Cryptosporidium Parvum 2
Z50587 Z50587 CHEMBL372 Homo Sapiens 2
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 2
Z80008 Z80008 CHEMBL612565 5637 (Epithelial Bladder Carcinoma Cells) 2
Z80017 Z80017 CHEMBL614023 A2780cisR (Cisplatin-resistant Ovarian Carcinoma Cells) 2
Z80018 Z80018 CHEMBL613859 A-375 (Malignant Melanoma Cells) 2
Z80026 Z80026 CHEMBL613860 AGS (Gastric Adenocarcinoma Cells) 2
Z80039 Z80039 CHEMBL614526 BGC-823 (Stomach Adenocarcinoma Cells) 2
Z80052 Z80052 CHEMBL614533 C8166 (Leukemic T-cells) 2
Z80054 Z80054 CHEMBL614058 Caco-2 (Colon Adenocarcinoma Cells) 2
Z80055 Z80055 CHEMBL614067 CAKI-1 (Kidney Carcinoma Cells) 2
Z80068 Z80068 CHEMBL614542 CCRF-SB (Lymphoblastic Leukemia Cells) 2
Z80092 Z80092 CHEMBL614031 CHO-K1 (Ovarian Cells) 2
Z80105 Z80105 CHEMBL613854 COR-L23 (Lung Carcinoma Cells) 2
Z80114 Z80114 CHEMBL614281 Daudi (Burkitts Lymphoma Cells) 2
Z80126 Z80126 CHEMBL614289 DuPro 2
Z80138 Z80138 CHEMBL614036 G-361 (Melanoma Cells) 2
Z80145 Z80145 CHEMBL614045 H69 2
Z80175 Z80175 CHEMBL614585 IMR-32 (Neuroblastoma Cells) 2
Z80243 Z80243 CHEMBL614334 MDA-MB-453 (Breast Adenocarcinoma Cells) 2
Z80267 Z80267 CHEMBL614352 MKN-1 2
Z80291 Z80291 CHEMBL614181 MRC5 (Embryonic Lung Fibroblast Cells) 2
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 2
Z80322 Z80322 CHEMBL614135 NCI-H358 (Lung Carcinama Cells) 2
Z80330 Z80330 CHEMBL614197 NCI-N87 2
Z80357 Z80357 CHEMBL612555 OVCAR-8 (Ovarian Adenocarcinoma Cells) 2
Z80367 Z80367 CHEMBL614220 P388/S 2
Z80389 Z80389 CHEMBL614140 PC-14 2
Z80414 Z80414 CHEMBL614628 Raji (B-lymphoblastic Cells) 2
Z80441 Z80441 CHEMBL614889 RXF 944 2
Z80472 Z80472 CHEMBL612542 SiHa (Cervical Squamous Cell Carcinoma) 2
Z80477 Z80477 CHEMBL614912 SK_HEP1 (Hepatoma Cells) 2
Z80479 Z80479 CHEMBL614914 SK-MEL (Melanoma Cells) 2
Z80481 Z80481 CHEMBL614916 SK-MEL-1 (Metastatic Melanoma Cells) 2
Z80490 Z80490 CHEMBL614923 SK-MES-1 2
Z80491 Z80491 CHEMBL614163 SK-N-MC (Neuroepithelioma Cells) 2
Z80492 Z80492 CHEMBL614924 SK-N-SH (Neuroblastoma Cells) 2
Z80495 Z80495 CHEMBL614927 SK-VLB 2
Z80499 Z80499 CHEMBL614164 SNB-19 (Glioma Cells) 2
Z80503 Z80503 CHEMBL614931 SNU1 2
Z80509 Z80509 CHEMBL614935 SNU-638 (Gastric Carcinoma Cells) 2
Z80526 Z80526 CHEMBL612544 SW480 (Colon Adenocarcinoma Cells) 2
Z80551 Z80551 CHEMBL614056 TK-10 (Renal Carcinoma Cells) 2
Z80575 Z80575 CHEMBL614388 UO-31 (Renal Carcinoma Cells) 2
Z80581 Z80581 CHEMBL614248 VA13 2
Z80583 Z80583 CHEMBL391 Vero (Kidney Cells) 2
Z80595 Z80595 CHEMBL612810 WIL2-NS (Lymphoblastoid Cells) 2
Z80600 Z80600 CHEMBL613533 XF498 (Glioma Cells) 2
Z80716 Z80716 CHEMBL614363 BT-549 Breast Cancer Cell Line 2
Z80726 Z80726 CHEMBL614367 TRAMP-C1A (Prostate Carcinoma Cells) 2
Z80730 Z80730 CHEMBL614368 C2D Cell Line 2
Z80731 Z80731 CHEMBL613541 C2G Cell Line 2
Z80732 Z80732 CHEMBL614369 TRAMP-C2H (Prostate Carcinoma Cells) 2
Z80735 Z80735 CHEMBL614739 C38 (Colon Carcinoma) 2
Z80768 Z80768 CHEMBL614455 CH1 (Ovarian Carcinoma Cells) 2
Z80784 Z80784 CHEMBL614462 Col2 (Colon Carcinoma Cells) 2
Z80801 Z80801 CHEMBL614151 CRL-7065 Cell Line 2
Z80819 Z80819 CHEMBL614484 J774.2 2
Z80834 Z80834 CHEMBL614487 EKVX (Non-small Cell Lung Carcinoma Cells) 2
Z80846 Z80846 CHEMBL614493 F460pv8/eto Cell Line 2
Z80852 Z80852 CHEMBL614069 A-431 (Epidermoid Carcinoma Cells) 2
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 2
Z80887 Z80887 CHEMBL614802 H2981 Cell Line 2
Z80920 Z80920 CHEMBL613855 HCC 2998 (Colon Adenocarcinoma Cells) 2
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 2
Z80943 Z80943 CHEMBL614819 HEL 299 2
Z80945 Z80945 CHEMBL614735 HEp-2 (Laryngeal Carcinoma Cells) 2
Z80972 Z80972 CHEMBL613889 HOP-92 (Non-small Cell Lung Carcinoma Cells) 2
Z81005 Z81005 CHEMBL614839 HTB-54 Cell Line 2
Z81006 Z81006 CHEMBL612259 Human Breast 401NL Tumor Cell Line 2
Z81025 Z81025 CHEMBL613890 Human Lung LXF 529L Tumor Cell Line 2
Z81026 Z81026 CHEMBL614689 Human Lung LXF 629L Tumor Cell Line 2
Z81028 Z81028 CHEMBL613892 Human Melanoma Cell Line 2
Z81043 Z81043 CHEMBL613969 N592 2
Z81065 Z81065 CHEMBL613984 IGROV-1 (Ovarian Adenocarcinoma Cells) 2
Z81101 Z81101 CHEMBL614010 KBM-3 Cell Line 2
Z81102 Z81102 CHEMBL613994 KBM-3/DOX Cell Line 2
Z81134 Z81134 CHEMBL614650 L2987 (Lung Adenocarcinoma Cells) 2
Z81160 Z81160 CHEMBL614088 Lewis Lung Carcinoma Cell Line 2
Z81164 Z81164 CHEMBL614091 LL Cell Line 2
Z81167 Z81167 CHEMBL614093 LLTC Cell Line 2
Z81211 Z81211 CHEMBL614109 LXFL529 Cell Line 2
Z81244 Z81244 CHEMBL614123 J774 (Macrophage Cells) 2
Z81257 Z81257 CHEMBL614732 MEL-AC Cell Line 2
Z81261 Z81261 CHEMBL614127 UACC-375 2
Z81277 Z81277 CHEMBL613287 NCI-N417 2
Z81278 Z81278 CHEMBL614451 SNB-75 (Glioblastoma Cells) 2
Z81284 Z81284 CHEMBL614999 NCI-H647 2
Z81316 Z81316 CHEMBL614072 BT-549 (Breast Ductal Carcinoma Cells) 2
Z81325 Z81325 CHEMBL614300 SR (Leukemia Cells) 2
Z81341 Z81341 CHEMBL614310 Tumor Cell Lines 2
Z103196 Z103196 CHEMBL1075381 22RV1 1
Z50426 Z50426 CHEMBL612856 Plasmodium Falciparum (isolate K1 / Thailand) 1
Z50460 Z50460 CHEMBL612879 Leishmania Major 1
Z50466 Z50466 CHEMBL368 Trypanosoma Cruzi 1
Z50725 Z50725 CHEMBL612348 Trypanosoma Brucei Rhodesiense 1
Z80060 Z80060 CHEMBL614536 CAPAN-1 (Pancreatic Adenocarcinoma Cells) 1
Z80134 Z80134 CHEMBL614295 EVSA-T 1
Z80316 Z80316 CHEMBL614771 NCI-H128 1
Z80335 Z80335 CHEMBL614200 NHDF 1
Z80342 Z80342 CHEMBL612554 NSCLC (Non-small Cell Lung Carcinoma Cells) 1
Z80502 Z80502 CHEMBL612543 SNB-78 (Glioblastoma Cells) 1
Z80514 Z80514 CHEMBL614166 St-4 (Stomach Carcinoma Cells) 1
Z80571 Z80571 CHEMBL612797 UCLA P-3 1
Z80585 Z80585 CHEMBL613532 WALKER 1
Z80606 Z80606 CHEMBL612816 YOSHIDA (Sarcoma Cells) 1
Z80957 Z80957 CHEMBL614734 HMEC (Microvascular Endothelial Cells) 1
Z81159 Z81159 CHEMBL614087 Lewis Cell Line 1
Z81227 Z81227 CHEMBL614116 M-19 Cell Line 1