UCSF

Squalene Monooxygenase, Human (9 Compounds)

Swissprot:
ERG1_HUMAN
Stitch:
ERG1_HUMAN
UniProt:
Q14534
ChEMBL:
CHEMBL3592
Reactome:
REACT_147904
REACT_9405
PDB:
SQLE

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 9 1 1 1
Binding ≤ 1μM 5 1 1 1
Functional ≤ 10μM 22 1 1 1

Reactome Network (2)

Uniprot Swissprot Chembl Description Number Shared
ERG7_HUMAN P48449 CHEMBL3593 Lanosterol Synthase, Human 2
FDFT_HUMAN P37268 CHEMBL3338 Squalene Synthetase, Human 2

Cholesterol biosynthesis

Uniprot Swissprot Chembl Description Number Shared
ERG7_HUMAN P48449 CHEMBL3593 Lanosterol Synthase, Human 2
FDFT_HUMAN P37268 CHEMBL3338 Squalene Synthetase, Human 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ERG1_RAT P52020 CHEMBL4241 Squalene Monooxygenase, Rat 32 4 5 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ERG7_HUMAN P48449 CHEMBL3593 Lanosterol Synthase, Human 106 5 0 10
ERG_HUMAN P11308 CHEMBL1293191 Transcriptional Regulator ERG, Human 26 0 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
ERG1-1-E Squalene Monooxygenase (cluster #1 Of 3), Eukaryotic 11 2 2 1
ERG1-2-E Squalene Monooxygenase (cluster #2 Of 3), Eukaryotic 10 0 0 0
ERG1-3-E Squalene Monooxygenase (cluster #3 Of 3), Eukaryotic 19 3 4 1
Uniprot Swissprot Chembl Description Number Shared
ERG7_HUMAN P48449 CHEMBL3593 Lanosterol Synthase, Human 2
FDFT_HUMAN P37268 CHEMBL3338 Squalene Synthetase, Human 2
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 2
A7L861_PIG A7L861 CHEMBL5436 Squalene Epoxidase, Pig 1
ERG1_RAT P52020 CHEMBL4241 Squalene Monooxygenase, Rat 1
Z50587 Z50587 CHEMBL372 Homo Sapiens 1
Z50588 Z50588 CHEMBL373 Canis Familiaris 1
Z81135 Z81135 CHEMBL614793 L6 (Skeletal Muscle Myoblast Cells) 1