| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 9 | 1 | 1 | 1 |
| Binding ≤ 1μM | 5 | 1 | 1 | 1 |
| Functional ≤ 10μM | 22 | 1 | 1 | 1 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_147904 | Activation of gene expression by SREBF (SREBP) | Homo sapiens |
| REACT_9405 | Cholesterol biosynthesis | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| ERG7_HUMAN | P48449 | CHEMBL3593 | Lanosterol Synthase, Human | 2 |
| FDFT_HUMAN | P37268 | CHEMBL3338 | Squalene Synthetase, Human | 2 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| ERG7_HUMAN | P48449 | CHEMBL3593 | Lanosterol Synthase, Human | 2 |
| FDFT_HUMAN | P37268 | CHEMBL3338 | Squalene Synthetase, Human | 2 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| ERG1_RAT | P52020 | CHEMBL4241 | Squalene Monooxygenase, Rat | 32 | 4 | 5 | 1 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| ERG7_HUMAN | P48449 | CHEMBL3593 | Lanosterol Synthase, Human | 106 | 5 | 0 | 10 |
| ERG_HUMAN | P11308 | CHEMBL1293191 | Transcriptional Regulator ERG, Human | 26 | 0 | 0 | 0 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| ERG1-1-E | Squalene Monooxygenase (cluster #1 Of 3), Eukaryotic | 11 | 2 | 2 | 1 |
| ERG1-2-E | Squalene Monooxygenase (cluster #2 Of 3), Eukaryotic | 10 | 0 | 0 | 0 |
| ERG1-3-E | Squalene Monooxygenase (cluster #3 Of 3), Eukaryotic | 19 | 3 | 4 | 1 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| ERG7_HUMAN | P48449 | CHEMBL3593 | Lanosterol Synthase, Human | 2 |
| FDFT_HUMAN | P37268 | CHEMBL3338 | Squalene Synthetase, Human | 2 |
| Z50597 | Z50597 | CHEMBL376 | Rattus Norvegicus | 2 |
| Z81020 | Z81020 | CHEMBL395 | HepG2 (Hepatoblastoma Cells) | 2 |
| A7L861_PIG | A7L861 | CHEMBL5436 | Squalene Epoxidase, Pig | 1 |
| ERG1_RAT | P52020 | CHEMBL4241 | Squalene Monooxygenase, Rat | 1 |
| Z50587 | Z50587 | CHEMBL372 | Homo Sapiens | 1 |
| Z50588 | Z50588 | CHEMBL373 | Canis Familiaris | 1 |
| Z81135 | Z81135 | CHEMBL614793 | L6 (Skeletal Muscle Myoblast Cells) | 1 |