| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 106 | 5 | 0 | 10 |
| Binding ≤ 1μM | 89 | 4 | 0 | 9 |
| Functional ≤ 10μM | 4 | 1 | 1 | 1 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_147904 | Activation of gene expression by SREBF (SREBP) | Homo sapiens |
| REACT_9405 | Cholesterol biosynthesis | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| ERG1_HUMAN | Q14534 | CHEMBL3592 | Squalene Monooxygenase, Human | 2 |
| FDFT_HUMAN | P37268 | CHEMBL3338 | Squalene Synthetase, Human | 2 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| ERG1_HUMAN | Q14534 | CHEMBL3592 | Squalene Monooxygenase, Human | 2 |
| FDFT_HUMAN | P37268 | CHEMBL3338 | Squalene Synthetase, Human | 2 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| ERG7_CANAL | Q04782 | CHEMBL1075056 | Lanosterol Synthase, Canal | 4 | 0 | 0 | 0 |
| ERG7_PNECA | Q96WJ0 | CHEMBL1075204 | Lanosterol Synthase, Pneca | 4 | 0 | 0 | 0 |
| ERG7_RAT | P48450 | CHEMBL3262 | Lanosterol Synthase, Rat | 96 | 1 | 0 | 0 |
| ERG7_YEAST | P38604 | CHEMBL5355 | Lanosterol Synthase, Yeast | 25 | 2 | 0 | 6 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| ERG1_HUMAN | Q14534 | CHEMBL3592 | Squalene Monooxygenase, Human | 9 | 1 | 1 | 1 |
| ERG_HUMAN | P11308 | CHEMBL1293191 | Transcriptional Regulator ERG, Human | 26 | 0 | 0 | 0 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| ERG7-1-E | Lanosterol Synthase (cluster #1 Of 3), Eukaryotic | 84 | 5 | 0 | 9 |
| ERG7-1-F | Lanosterol Synthase (cluster #1 Of 2), Fungal | 23 | 2 | 0 | 6 |
| ERG7-2-E | Lanosterol Synthase (cluster #2 Of 3), Eukaryotic | 33 | 0 | 0 | 1 |
| ERG7-2-F | Lanosterol Synthase (cluster #2 Of 2), Fungal | 8 | 0 | 0 | 0 |
| ERG7-3-E | Lanosterol Synthase (cluster #3 Of 3), Eukaryotic | 60 | 0 | 0 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| SQHC_ALIAD | P33247 | CHEMBL3569 | Squalene-hopene Cyclase, Aliad | 28 |
| ERG7_RAT | P48450 | CHEMBL3262 | Lanosterol Synthase, Rat | 26 |
| ERG7_YEAST | P38604 | CHEMBL5355 | Lanosterol Synthase, Yeast | 24 |
| CAS1_ARATH | P38605 | CHEMBL5356 | Cycloartenol Synthase, Arath | 22 |
| ERG7_CANAL | Q04782 | CHEMBL1075056 | Lanosterol Synthase, Canal | 4 |
| ERG7_PNECA | Q96WJ0 | CHEMBL1075204 | Lanosterol Synthase, Pneca | 3 |
| ERG1_HUMAN | Q14534 | CHEMBL3592 | Squalene Monooxygenase, Human | 2 |
| FDFT_HUMAN | P37268 | CHEMBL3338 | Squalene Synthetase, Human | 2 |
| Z50597 | Z50597 | CHEMBL376 | Rattus Norvegicus | 2 |
| Z81020 | Z81020 | CHEMBL395 | HepG2 (Hepatoblastoma Cells) | 2 |
| Z50587 | Z50587 | CHEMBL372 | Homo Sapiens | 1 |
| Z50588 | Z50588 | CHEMBL373 | Canis Familiaris | 1 |
| Z81135 | Z81135 | CHEMBL614793 | L6 (Skeletal Muscle Myoblast Cells) | 1 |
