UCSF

Lanosterol Synthase, Yeast (25 Compounds)

Swissprot:
ERG7_YEAST
Stitch:
ERG7_YEAST
UniProt:
P38604
ChEMBL:
CHEMBL5355
Reactome:
REACT_253879
PDB:
ERG7

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 25 2 0 6
Binding ≤ 1μM 19 2 0 6

Reactome Network (1)

Reactome ID Description Species
REACT_253879 Cholesterol biosynthesis Saccharomyces cerevisiae
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ERG7_CANAL Q04782 CHEMBL1075056 Lanosterol Synthase, Canal 4 0 0 0
ERG7_HUMAN P48449 CHEMBL3593 Lanosterol Synthase, Human 106 5 0 10
ERG7_PNECA Q96WJ0 CHEMBL1075204 Lanosterol Synthase, Pneca 4 0 0 0
ERG7_RAT P48450 CHEMBL3262 Lanosterol Synthase, Rat 96 1 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 52 27 25 22

Clustered By Gene (0)

Clustered By Organism (4)

Code Description Substances Purchasable Natural In Man
ERG7-1-E Lanosterol Synthase (cluster #1 Of 3), Eukaryotic 84 5 0 9
ERG7-1-F Lanosterol Synthase (cluster #1 Of 2), Fungal 23 2 0 6
ERG7-2-E Lanosterol Synthase (cluster #2 Of 3), Eukaryotic 33 0 0 1
ERG7-2-F Lanosterol Synthase (cluster #2 Of 2), Fungal 8 0 0 0
ERG7-3-E Lanosterol Synthase (cluster #3 Of 3), Eukaryotic 60 0 0 0
Uniprot Swissprot Chembl Description Number Shared
ERG7_HUMAN P48449 CHEMBL3593 Lanosterol Synthase, Human 24
CAS1_ARATH P38605 CHEMBL5356 Cycloartenol Synthase, Arath 23
SQHC_ALIAD P33247 CHEMBL3569 Squalene-hopene Cyclase, Aliad 8
ERG7_PNECA Q96WJ0 CHEMBL1075204 Lanosterol Synthase, Pneca 2