UCSF

Squalene Monooxygenase, Rat (32 Compounds)

Swissprot:
ERG1_RAT
Stitch:
ERG1_RAT
UniProt:
P52020
ChEMBL:
CHEMBL4241
Reactome:
REACT_198613
REACT_238041
PDB:
Sqle

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 32 4 5 1
Binding ≤ 1μM 18 1 2 0

Reactome Network (2)

Reactome ID Description Species
REACT_198613 Activation of gene expression by SREBF (SREBP) Rattus norvegicus
REACT_238041 Cholesterol biosynthesis Rattus norvegicus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ERG1_HUMAN Q14534 CHEMBL3592 Squalene Monooxygenase, Human 9 1 1 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ERG7_RAT P48450 CHEMBL3262 Lanosterol Synthase, Rat 96 1 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
ERG1-1-E Squalene Monooxygenase (cluster #1 Of 3), Eukaryotic 11 2 2 1
ERG1-2-E Squalene Monooxygenase (cluster #2 Of 3), Eukaryotic 10 0 0 0
ERG1-3-E Squalene Monooxygenase (cluster #3 Of 3), Eukaryotic 19 3 4 1
Uniprot Swissprot Chembl Description Number Shared
6PGD_HUMAN P52209 CHEMBL3404 6-phosphogluconate Dehydrogenase, Human 1
A3EZI9_9HEPC A3EZI9 CHEMBL4893 Hepatitis C Virus NS3 Protease/helicase, 9hepc 1
BCL2_HUMAN P10415 CHEMBL4860 Apoptosis Regulator Bcl-2, Human 1
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 1
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 1
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 1
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 1
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 1
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 1
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 1
CSK21_RAT P19139 CHEMBL2661 Casein Kinase II Alpha, Rat 1
CSK2B_RAT P67874 CHEMBL2463 Casein Kinase II Beta, Rat 1
ERG1_HUMAN Q14534 CHEMBL3592 Squalene Monooxygenase, Human 1
FGR_RAT Q6P6U0 CHEMBL4362 Tyrosine-protein Kinase FGR, Rat 1
G6PD_YEAST P11412 CHEMBL1075249 Glucose-6-phosphate 1-dehydrogenase, Yeast 1
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 1
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 1
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 1
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
KSYK_RAT Q64725 CHEMBL4364 Tyrosine-protein Kinase SYK, Rat 1
LYN_RAT Q07014 CHEMBL4363 Tyrosine-protein Kinase Lyn, Rat 1
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 1
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 1
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 1
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 1
Q965D5_PLAFA Q965D5 CHEMBL4150 Enoyl-acyl-carrier Protein Reductase, Plafa 1
Q965D6_PLAFA Q965D6 CHEMBL4513 3-oxoacyl-acyl-carrier Protein Reductase, Plafa 1
Q965D7_PLAFA Q965D7 CHEMBL4512 Fatty Acid Synthase, Plafa 1
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 1