UCSF

CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human (247 Compounds)

Swissprot:
KAPCA_HUMAN
Stitch:
KAPCA_HUMAN
UniProt:
P17612
ChEMBL:
CHEMBL4101
Reactome:
REACT_20625
REACT_15334
REACT_24970
REACT_18274
REACT_1520
REACT_494
REACT_23837
REACT_15364
REACT_15451
REACT_15530
REACT_1946
REACT_15497
REACT_1525
REACT_23898
REACT_15296
REACT_18325
REACT_160315
REACT_24023
REACT_228166
PDB:
2GU8 (DOCK)
3AGL (DOCK)
3AGM (DOCK)
3AMA (DOCK)
3AMB (DOCK)
3L9L (DOCK)
3L9M (DOCK)
3L9N (DOCK)
3MVJ (DOCK)
3NX8 (DOCK)
3OOG (DOCK)
3OVV (DOCK)
3OWP (DOCK)
3OXT (DOCK)
3P0M (DOCK)
3POO (DOCK)
PRKACA

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 247 29 9 19
Binding ≤ 1μM 120 12 8 11
Functional ≤ 10μM 8 0 0 0

Reactome Network (19)

Reactome ID Description Species
REACT_20625 CREB phosphorylation through the activation of Adenylate Cyclase Homo sapiens
REACT_15334 DARPP-32 events Homo sapiens
REACT_24970 Factors involved in megakaryocyte development and platelet production Homo sapiens
REACT_18274 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Homo sapiens
REACT_1520 Gluconeogenesis Homo sapiens
REACT_494 Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Homo sapiens
REACT_23837 Interleukin-3, 5 and GM-CSF signaling Homo sapiens
REACT_15364 Loss of Nlp from mitotic centrosomes Homo sapiens
REACT_15451 Loss of proteins required for interphase microtubule organization from the ce Homo sapiens
REACT_15530 PKA activation Homo sapiens
REACT_1946 PKA activation in glucagon signalling Homo sapiens
REACT_15497 PKA-mediated phosphorylation of CREB Homo sapiens
REACT_1525 PKA-mediated phosphorylation of key metabolic factors Homo sapiens
REACT_23898 Rap1 signalling Homo sapiens
REACT_15296 Recruitment of mitotic centrosome proteins and complexes Homo sapiens
REACT_18325 Regulation of insulin secretion Homo sapiens
REACT_160315 Regulation of PLK1 Activity at G2/M Transition Homo sapiens
REACT_24023 Vasopressin regulates renal water homeostasis via Aquaporins Homo sapiens
REACT_228166 VEGFA-VEGFR2 Pathway Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203

DARPP-32 events

Uniprot Swissprot Chembl Description Number Shared
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 4
KAP0_HUMAN P10644 CHEMBL4928 CAMP-dependent Protein Kinase Type I-alpha Regulatory Subunit, Human 3
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203

Factors involved in megakaryocyte development and platelet production

Uniprot Swissprot Chembl Description Number Shared
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 6
AKAP1_HUMAN Q92667 CHEMBL3678 Protein Kinase A Anchoring Protein 1, Human 12
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 41
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 4
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 4
KAP0_HUMAN P10644 CHEMBL4928 CAMP-dependent Protein Kinase Type I-alpha Regulatory Subunit, Human 3
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 1

Glucagon-like Peptide-1 (GLP1) regulates insulin secretion

Uniprot Swissprot Chembl Description Number Shared
KAP0_HUMAN P10644 CHEMBL4928 CAMP-dependent Protein Kinase Type I-alpha Regulatory Subunit, Human 3
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203

Gluconeogenesis

Uniprot Swissprot Chembl Description Number Shared
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203

Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis

Uniprot Swissprot Chembl Description Number Shared
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203

Interleukin-3, 5 and GM-CSF signaling

Uniprot Swissprot Chembl Description Number Shared
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 4
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 1
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 1
TEC_HUMAN P42680 CHEMBL4246 Tyrosine-protein Kinase TEC, Human 1

Loss of Nlp from mitotic centrosomes

Uniprot Swissprot Chembl Description Number Shared
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 15
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 6
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 6
NEK2_HUMAN P51955 CHEMBL3835 Serine/threonine-protein Kinase NEK2, Human 1
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 1
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 2

Loss of proteins required for interphase microtubule organization from the ce

Uniprot Swissprot Chembl Description Number Shared
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 15
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 6
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 6
NEK2_HUMAN P51955 CHEMBL3835 Serine/threonine-protein Kinase NEK2, Human 1
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 1
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 2

PKA activation

Uniprot Swissprot Chembl Description Number Shared
KAP0_HUMAN P10644 CHEMBL4928 CAMP-dependent Protein Kinase Type I-alpha Regulatory Subunit, Human 3
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203

PKA activation in glucagon signalling

Uniprot Swissprot Chembl Description Number Shared
KAP0_HUMAN P10644 CHEMBL4928 CAMP-dependent Protein Kinase Type I-alpha Regulatory Subunit, Human 3
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203

PKA-mediated phosphorylation of CREB

Uniprot Swissprot Chembl Description Number Shared
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203

PKA-mediated phosphorylation of key metabolic factors

Uniprot Swissprot Chembl Description Number Shared
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203

Rap1 signalling

Uniprot Swissprot Chembl Description Number Shared
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 3

Recruitment of mitotic centrosome proteins and complexes

Uniprot Swissprot Chembl Description Number Shared
CD11A_HUMAN Q9UQ88 CHEMBL5416 PITSLRE Serine/threonine-protein Kinase CDC2L2, Human 2
CD11B_HUMAN P21127 CHEMBL5808 PITSLRE Serine/threonine-protein Kinase CDC2L1, Human 2
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 15
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 6
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 6
NEK2_HUMAN P51955 CHEMBL3835 Serine/threonine-protein Kinase NEK2, Human 1
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 1
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 2

Regulation of insulin secretion

Uniprot Swissprot Chembl Description Number Shared
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203

Regulation of PLK1 Activity at G2/M Transition

Uniprot Swissprot Chembl Description Number Shared
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 3
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 9
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 9
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 15
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 6
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 6
NEK2_HUMAN P51955 CHEMBL3835 Serine/threonine-protein Kinase NEK2, Human 1
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 1
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 2

Vasopressin regulates renal water homeostasis via Aquaporins

Uniprot Swissprot Chembl Description Number Shared
KAP0_HUMAN P10644 CHEMBL4928 CAMP-dependent Protein Kinase Type I-alpha Regulatory Subunit, Human 3
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203

VEGFA-VEGFR2 Pathway

Uniprot Swissprot Chembl Description Number Shared
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 2
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 5
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203
MAPK2_HUMAN P49137 CHEMBL2208 MAP Kinase-activated Protein Kinase 2, Human 2
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 3
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 3
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 2
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 3
PAK2_HUMAN Q13177 CHEMBL4487 Serine/threonine-protein Kinase PAK 2, Human 1
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 1
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 1
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 16
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 4
UFO_HUMAN P30530 CHEMBL4895 Tyrosine-protein Kinase Receptor UFO, Human 3
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 10
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
KAPCA_BOVIN P00517 CHEMBL2654 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Bovin 152 8 1 3
KAPCA_MOUSE P05132 CHEMBL4991 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Mouse 4 3 3 3
KAPCA_RAT P27791 CHEMBL3390 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rat 5 3 3 1

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
KAPCA-1-E CAMP-dependent Protein Kinase Alpha-catalytic Subunit (cluster #1 Of 4), Eukaryotic 394 28 12 17
KAPCA-2-E CAMP-dependent Protein Kinase Alpha-catalytic Subunit (cluster #2 Of 4), Eukaryotic 13 9 1 6
KAPCA-3-E CAMP-dependent Protein Kinase Alpha-catalytic Subunit (cluster #3 Of 4), Eukaryotic 1 1 1 1
KAPCA-4-E CAMP-dependent Protein Kinase Alpha-catalytic Subunit (cluster #4 Of 4), Eukaryotic 1 1 1 0
Uniprot Swissprot Chembl Description Number Shared
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 206
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 203
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 104
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 103
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 102
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 102
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 102
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 97
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 49
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 43
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 43
KPCD3_HUMAN O94806 CHEMBL2595 Protein Kinase C Nu, Human 42
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 41
KPCI_HUMAN P41743 CHEMBL2598 Protein Kinase C Iota, Human 41
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 41
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 35
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 35
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 34
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 33
PHKG1_HUMAN Q16816 CHEMBL4004 Phosphorylase Kinase Gamma Subunit 1, Human 33
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase Kinase Gamma Subunit 2, Human 32
KAPCB_BOVIN P05131 CHEMBL3279 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Bovin 31
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 27
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 27
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 23
KS6B1_HUMAN P23443 CHEMBL4501 Ribosomal Protein S6 Kinase 1, Human 21
KCC2A_HUMAN Q9UQM7 CHEMBL4147 CaM Kinase II Alpha, Human 18
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 17
KAPCA_BOVIN P00517 CHEMBL2654 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Bovin 17
KCC2B_HUMAN Q13554 CHEMBL4121 CaM Kinase II Beta, Human 17
KCC2D_HUMAN Q13557 CHEMBL2801 CaM Kinase II Delta, Human 16
KCC2G_HUMAN Q13555 CHEMBL3829 CaM Kinase II Gamma, Human 16
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 16
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 15
Q95J97_RABIT Q95J97 CHEMBL4885 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rabit 15
AKAP1_HUMAN Q92667 CHEMBL3678 Protein Kinase A Anchoring Protein 1, Human 12
AKAP2_HUMAN Q9Y2D5 CHEMBL3899 Protein Kinase A Anchoring Protein 2, Human 12
KS6A5_HUMAN O75582 CHEMBL4237 Ribosomal Protein S6 Kinase Alpha 5, Human 12
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 10
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 9
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 9
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 9
KGP2_HUMAN Q13237 CHEMBL2896 CGMP-dependent Protein Kinase 2, Human 9
KS6A4_HUMAN O75676 CHEMBL3125 Ribosomal Protein S6 Kinase Alpha 4, Human 9
KS6A6_HUMAN Q9UK32 CHEMBL4924 Ribosomal Protein S6 Kinase Alpha 6, Human 9
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 9
KGP1_HUMAN Q13976 CHEMBL4273 CGMP-dependent Protein Kinase 1 Beta, Human 8
KS6A1_HUMAN Q15418 CHEMBL2553 Ribosomal Protein S6 Kinase Alpha 1, Human 8
KS6A2_HUMAN Q15349 CHEMBL3906 Ribosomal Protein S6 Kinase Alpha 2, Human 8
KS6A3_HUMAN P51812 CHEMBL2345 Ribosomal Protein S6 Kinase Alpha 3, Human 8
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 7
KPCA_RAT P05696 CHEMBL2855 Protein Kinase C Alpha, Rat 7
KPCB_RAT P68403 CHEMBL3020 Protein Kinase C Beta, Rat 7
KPCD_RAT P09215 CHEMBL3633 Protein Kinase C Delta, Rat 7
KPCE_RAT P09216 CHEMBL3424 Protein Kinase C Epsilon, Rat 7
KPCG_RAT P63319 CHEMBL3604 Protein Kinase C Gamma, Rat 7
KPCL_RAT Q64617 CHEMBL3990 Protein Kinase C Eta, Rat 7
KPCT_RAT Q9WTQ0 CHEMBL4563 Protein Kinase C Theta, Rat 7
KPCZ_RAT P09217 CHEMBL5379 Protein Kinase C Zeta, Rat 7
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 7
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 6
CHK1_HUMAN O14757 CHEMBL4630 Serine/threonine-protein Kinase Chk1, Human 6
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 6
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 6
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 6
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 6
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 6
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 6
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 6
KS6B2_HUMAN Q9UBS0 CHEMBL3111 Ribosomal Protein S6 Kinase 2, Human 6
MYLK_HUMAN Q15746 CHEMBL2428 Myosin Light Chain Kinase, Smooth Muscle, Human 6
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 6
AURKC_HUMAN Q9UQB9 CHEMBL3935 Serine/threonine-protein Kinase Aurora-C, Human 5
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 5
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 5
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 5
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 5
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 5
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 5
KC1G2_HUMAN P78368 CHEMBL2543 Casein Kinase I Gamma 2, Human 5
LATS2_HUMAN Q9NRM7 CHEMBL5907 Serine/threonine-protein Kinase LATS2, Human 5
MK01_HUMAN P28482 CHEMBL4040 MAP Kinase ERK2, Human 5
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 5
MK09_HUMAN P45984 CHEMBL4179 C-Jun N-terminal Kinase 2, Human 5
SLK_HUMAN Q9H2G2 CHEMBL4202 Serine/threonine-protein Kinase 2, Human 5
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 5
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 5
Z80840 Z80840 CHEMBL614490 ER22 Cell Line 5
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 4
CDK9_HUMAN P50750 CHEMBL3116 Cyclin-dependent Kinase 9, Human 4
CLK4_HUMAN Q9HAZ1 CHEMBL4203 Dual Specificity Protein Kinase CLK4, Human 4
CSK22_HUMAN P19784 CHEMBL4070 Casein Kinase II Alpha (prime), Human 4
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 4
CSK_HUMAN P41240 CHEMBL2634 Tyrosine-protein Kinase CSK, Human 4
CTRO_HUMAN O14578 CHEMBL5579 Citron Rho-interacting Kinase, Human 4
DDR1_HUMAN Q08345 CHEMBL5319 Epithelial Discoidin Domain-containing Receptor 1, Human 4
DDR2_HUMAN Q16832 CHEMBL5122 Discoidin Domain-containing Receptor 2, Human 4
EPHA6_HUMAN Q9UF33 CHEMBL4526 Ephrin Type-A Receptor 6, Human 4
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 4
FRK_HUMAN P42685 CHEMBL4223 Tyrosine-protein Kinase FRK, Human 4
GAK_HUMAN O14976 CHEMBL4355 Serine/threonine-protein Kinase GAK, Human 4
HCK_HUMAN P08631 CHEMBL3234 Tyrosine-protein Kinase HCK, Human 4
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 4
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 4
KC1G1_HUMAN Q9HCP0 CHEMBL2426 Casein Kinase I Gamma 1, Human 4
KCC1A_HUMAN Q14012 CHEMBL2493 CaM Kinase I Alpha, Human 4
KCC4_HUMAN Q16566 CHEMBL2494 CaM Kinase IV, Human 4
M4K1_HUMAN Q92918 CHEMBL5749 Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human 4
M4K3_HUMAN Q8IVH8 CHEMBL5432 Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human 4
M4K5_HUMAN Q9Y4K4 CHEMBL4852 Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human 4
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 4
MK03_HUMAN P27361 CHEMBL3385 MAP Kinase ERK1, Human 4
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 4
MK15_HUMAN Q8TD08 CHEMBL5198 Mitogen-activated Protein Kinase 15, Human 4
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 4
RET_HUMAN P07949 CHEMBL2041 Tyrosine-protein Kinase Receptor RET, Human 4
RIPK2_HUMAN O43353 CHEMBL5014 Serine/threonine-protein Kinase RIPK2, Human 4
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 4
STK10_HUMAN O94804 CHEMBL3981 Serine/threonine-protein Kinase 10, Human 4
STK33_HUMAN Q9BYT3 CHEMBL6005 Serine/threonine-protein Kinase 33, Human 4
STK3_HUMAN Q13188 CHEMBL4708 Serine/threonine-protein Kinase MST2, Human 4
TNIK_HUMAN Q9UKE5 CHEMBL4527 TRAF2- And NCK-interacting Kinase, Human 4
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 4
VGFR2_MOUSE P35918 CHEMBL3337 Vascular Endothelial Growth Factor Receptor 2, Mouse 4
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 3
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 3
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 3
CDK16_HUMAN Q00536 CHEMBL4597 Serine/threonine-protein Kinase PCTAIRE-1, Human 3
CDK19_HUMAN Q9BWU1 CHEMBL6002 Cell Division Cycle 2-like Protein Kinase 6, Human 3
CDK7_HUMAN P50613 CHEMBL3055 Cyclin-dependent Kinase 7, Human 3
CDK8_HUMAN P49336 CHEMBL5719 Cell Division Protein Kinase 8, Human 3
CLK2_HUMAN P49760 CHEMBL4225 Dual Specificity Protein Kinase CLK2, Human 3
CSF1R_HUMAN P07333 CHEMBL1844 Macrophage Colony Stimulating Factor Receptor, Human 3
CSK21_RAT P19139 CHEMBL2661 Casein Kinase II Alpha, Rat 3
CSK2B_RAT P67874 CHEMBL2463 Casein Kinase II Beta, Rat 3
DAPK3_HUMAN O43293 CHEMBL2468 Death-associated Protein Kinase 3, Human 3
E2AK2_HUMAN P19525 CHEMBL5785 Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human 3
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin Type-A Receptor 3, Human 3
FER_HUMAN P16591 CHEMBL3982 Tyrosine-protein Kinase FER, Human 3
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 3
INSRR_HUMAN P14616 CHEMBL5483 Insulin Receptor-related Protein, Human 3
KAP0_HUMAN P10644 CHEMBL4928 CAMP-dependent Protein Kinase Type I-alpha Regulatory Subunit, Human 3
KAP1_HUMAN P31321 CHEMBL2320 CAMP-dependent Protein Kinase Type I-beta Regulatory Subunit, Human 3
KAP2_BOVIN P00515 CHEMBL3654 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Bovin 3
KAP2_HUMAN P13861 CHEMBL2221 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Human 3
KAP3_HUMAN P31323 CHEMBL2270 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Human 3
KKCC1_HUMAN Q8N5S9 CHEMBL5256 CaM-kinase Kinase Alpha, Human 3
KKCC2_HUMAN Q96RR4 CHEMBL5284 CaM-kinase Kinase Beta, Human 3
KPCD2_HUMAN Q9BZL6 CHEMBL4900 Serine/threonine-protein Kinase D2, Human 3
LATS1_HUMAN O95835 CHEMBL6167 Serine/threonine-protein Kinase LATS1, Human 3
LTK_HUMAN P29376 CHEMBL5627 Leukocyte Tyrosine Kinase Receptor, Human 3
MERTK_HUMAN Q12866 CHEMBL5331 Proto-oncogene Tyrosine-protein Kinase MER, Human 3
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 3
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 3
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 3
MKNK1_HUMAN Q9BUB5 CHEMBL4718 MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human 3
MKNK2_HUMAN Q9HBH9 CHEMBL4204 MAP Kinase Signal-integrating Kinase 2, Human 3
MP2K2_HUMAN P36507 CHEMBL2964 Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human 3
MUSK_HUMAN O15146 CHEMBL5684 Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human 3
MYLK2_HUMAN Q9H1R3 CHEMBL2777 Myosin Light Chain Kinase 2, Human 3
NLK_HUMAN Q9UBE8 CHEMBL5364 Serine/threonine Protein Kinase NLK, Human 3
NTRK2_HUMAN Q16620 CHEMBL4898 Neurotrophic Tyrosine Kinase Receptor Type 2, Human 3
NTRK3_HUMAN Q16288 CHEMBL5608 NT-3 Growth Factor Receptor, Human 3
PAK4_HUMAN O96013 CHEMBL4482 Serine/threonine-protein Kinase PAK 4, Human 3
PKN1_HUMAN Q16512 CHEMBL3384 Protein Kinase N1, Human 3
PKN2_HUMAN Q16513 CHEMBL3032 Protein Kinase N2, Human 3
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 3
ST32B_HUMAN Q9NY57 CHEMBL5912 Serine/threonine-protein Kinase 32B, Human 3
STK36_HUMAN Q9NRP7 CHEMBL4312 Serine/threonine-protein Kinase 36, Human 3
STK4_HUMAN Q13043 CHEMBL4598 Serine/threonine-protein Kinase MST1, Human 3
TIE1_HUMAN P35590 CHEMBL5274 Tyrosine-protein Kinase Receptor Tie-1, Human 3
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 3
TTK_HUMAN P33981 CHEMBL3983 Dual Specificity Protein Kinase TTK, Human 3
TYK2_HUMAN P29597 CHEMBL3553 Tyrosine-protein Kinase TYK2, Human 3
UFO_HUMAN P30530 CHEMBL4895 Tyrosine-protein Kinase Receptor UFO, Human 3
Z104300 Z104300 CHEMBL1907606 Mitogen-activated Protein Kinase; ERK1/ERK2 3
AAK1_HUMAN Q2M2I8 CHEMBL3830 Adaptor-associated Kinase, Human 2
AAPK1_HUMAN Q13131 CHEMBL4045 AMP-activated Protein Kinase, Alpha-1 Subunit, Human 2
ABL2_HUMAN P42684 CHEMBL4014 Tyrosine-protein Kinase ABL2, Human 2
ACV1B_HUMAN P36896 CHEMBL5310 Activin Receptor Type-1B, Human 2
ANKK1_HUMAN Q8NFD2 CHEMBL5547 Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human 2
AVR2B_HUMAN Q13705 CHEMBL5466 Activin Receptor Type-2B, Human 2
BLK_HUMAN P51451 CHEMBL2250 Tyrosine-protein Kinase BLK, Human 2
BMP2K_HUMAN Q9NSY1 CHEMBL4522 BMP-2-inducible Protein Kinase, Human 2
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 2
CD11A_HUMAN Q9UQ88 CHEMBL5416 PITSLRE Serine/threonine-protein Kinase CDC2L2, Human 2
CD11B_HUMAN P21127 CHEMBL5808 PITSLRE Serine/threonine-protein Kinase CDC2L1, Human 2
CDC7_HUMAN O00311 CHEMBL5443 Cell Division Cycle 7-related Protein Kinase, Human 2
CDK14_HUMAN O94921 CHEMBL6162 Serine/threonine-protein Kinase PFTAIRE-1, Human 2
CDK17_HUMAN Q00537 CHEMBL5790 Serine/threonine-protein Kinase PCTAIRE-2, Human 2
CDK18_HUMAN Q07002 CHEMBL5316 Serine/threonine-protein Kinase PCTAIRE-3, Human 2
CDK1_YEAST P00546 CHEMBL5213 Cell Division Control Protein 28, Yeast 2
CDK3_HUMAN Q00526 CHEMBL4442 Cyclin-dependent Kinase 3, Human 2
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 2
CHK2_HUMAN O96017 CHEMBL2527 Serine/threonine-protein Kinase Chk2, Human 2
DAPK1_HUMAN P53355 CHEMBL2558 Death-associated Protein Kinase 1, Human 2
DAPK2_HUMAN Q9UIK4 CHEMBL3123 Death-associated Protein Kinase 2, Human 2
DMPK_HUMAN Q09013 CHEMBL5320 Myotonin-protein Kinase, Human 2
DYR1A_RAT Q63470 CHEMBL5508 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A, Rat 2
DYR1B_HUMAN Q9Y463 CHEMBL5543 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human 2
EPHA2_HUMAN P29317 CHEMBL2068 Ephrin Type-A Receptor 2, Human 2
EPHA4_HUMAN P54764 CHEMBL3988 Ephrin Type-A Receptor 4, Human 2
EPHA5_HUMAN P54756 CHEMBL3987 Ephrin Type-A Receptor 5, Human 2
EPHA7_HUMAN Q15375 CHEMBL4602 Ephrin Type-A Receptor 7, Human 2
EPHA8_HUMAN P29322 CHEMBL4134 Ephrin Type-A Receptor 8, Human 2
EPHB1_HUMAN P54762 CHEMBL5072 Ephrin Type-B Receptor 1, Human 2
EPHB2_HUMAN P29323 CHEMBL3290 Ephrin Type-B Receptor 2, Human 2
EPHB3_HUMAN P54753 CHEMBL4901 Ephrin Type-B Receptor 3, Human 2
EPHB4_HUMAN P54760 CHEMBL5147 Ephrin Type-B Receptor 4, Human 2
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 2
FES_HUMAN P07332 CHEMBL5455 Tyrosine-protein Kinase FES, Human 2
FGR_HUMAN P09769 CHEMBL4454 Tyrosine-protein Kinase FGR, Human 2
IKKB_HUMAN O14920 CHEMBL1991 Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human 2
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 2
KAP3_BOVIN P31322 CHEMBL3280 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Bovin 2
KC1AL_HUMAN Q8N752 CHEMBL5520 Casein Kinase I Isoform Alpha-like, Human 2
KCC1D_HUMAN Q8IU85 CHEMBL5073 CaM Kinase I Delta, Human 2
KCC2A_MOUSE P11798 CHEMBL3347 CaM Kinase II Alpha, Mouse 2
KCC2B_MOUSE P28652 CHEMBL4735 CaM Kinase II Beta, Mouse 2
KCC2G_MOUSE Q923T9 CHEMBL4456 CaM Kinase II Gamma, Mouse 2
KPB1_HUMAN P46020 CHEMBL2905 Phosphorylase Kinase Alpha M Subunit, Human 2
KPB2_HUMAN P46019 CHEMBL2906 Phosphorylase Kinase Alpha L Subunit, Human 2
KPBB_HUMAN Q93100 CHEMBL3844 Phosphorylase Kinase Beta Subunit, Human 2
KSYK_HUMAN P43405 CHEMBL2599 Tyrosine-protein Kinase SYK, Human 2
LIMK2_HUMAN P53671 CHEMBL5932 LIM Domain Kinase 2, Human 2
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 2
M3K9_HUMAN P80192 CHEMBL2872 Mitogen-activated Protein Kinase Kinase Kinase 9, Human 2
M4K4_HUMAN O95819 CHEMBL6166 Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human 2
MAPK2_HUMAN P49137 CHEMBL2208 MAP Kinase-activated Protein Kinase 2, Human 2
MARK2_HUMAN Q7KZI7 CHEMBL3831 MAP/microtubule Affinity-regulating Kinase 2, Human 2
MELK_HUMAN Q14680 CHEMBL4578 Maternal Embryonic Leucine Zipper Kinase, Human 2
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 2
MLTK_HUMAN Q9NYL2 CHEMBL3886 Mixed Lineage Kinase 7, Human 2
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 2
MP2K4_HUMAN P45985 CHEMBL2897 Dual Specificity Mitogen-activated Protein Kinase Kinase 4, Human 2
MRCKB_HUMAN Q9Y5S2 CHEMBL5052 Serine/threonine-protein Kinase MRCK Beta, Human 2
MRCKG_HUMAN Q6DT37 CHEMBL5615 Serine/threonine-protein Kinase MRCK Gamma, Human 2
MST4_HUMAN Q9P289 CHEMBL5941 Serine/threonine-protein Kinase MST4, Human 2
MYO3A_HUMAN Q8NEV4 CHEMBL5546 Myosin IIIA, Human 2
MYO3B_HUMAN Q8WXR4 CHEMBL5654 Myosin-IIIB, Human 2
NEK5_HUMAN Q6P3R8 CHEMBL5044 Serine/threonine-protein Kinase Nek5, Human 2
NUAK1_HUMAN O60285 CHEMBL5784 NUAK Family SNF1-like Kinase 1, Human 2
NUAK2_HUMAN Q9H093 CHEMBL5698 NUAK Family SNF1-like Kinase 2, Human 2
P90584_PLAFA P90584 CHEMBL4090 Protein Kinase Pfmrk, Plafa 2
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 2
PGFRA_RAT P20786 CHEMBL2513 Platelet-derived Growth Factor Receptor Alpha, Rat 2
PI42B_HUMAN P78356 CHEMBL5667 Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta, Human 2
PI51A_HUMAN Q99755 CHEMBL5969 Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha, Human 2
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 2
PIM2_HUMAN Q9P1W9 CHEMBL4523 Serine/threonine-protein Kinase PIM2, Human 2
PIM3_HUMAN Q86V86 CHEMBL5407 Serine/threonine-protein Kinase PIM3, Human 2
PLK3_HUMAN Q9H4B4 CHEMBL4897 Serine/threonine-protein Kinase PLK3, Human 2
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 2
PTK6_HUMAN Q13882 CHEMBL4601 Tyrosine-protein Kinase BRK, Human 2
Q17066_ASTPE Q17066 CHEMBL5124 Cdc2, Astpe 2
RIOK1_HUMAN Q9BRS2 CHEMBL5975 Serine/threonine-protein Kinase RIO1, Human 2
RIPK1_HUMAN Q13546 CHEMBL5464 Receptor-interacting Serine/threonine-protein Kinase 1, Human 2
ROCK2_RAT Q62868 CHEMBL5490 Rho-associated Protein Kinase 2, Rat 2
ROS1_HUMAN P08922 CHEMBL5568 Proto-oncogene Tyrosine-protein Kinase ROS, Human 2
SIK1_HUMAN P57059 CHEMBL6082 Serine/threonine-protein Kinase SIK1, Human 2
SRMS_HUMAN Q9H3Y6 CHEMBL5703 Tyrosine-protein Kinase Srms, Human 2
STK25_HUMAN O00506 CHEMBL5552 Serine/threonine-protein Kinase 25, Human 2
STK3_MOUSE Q9JI10 CHEMBL4310 Serine/threonine-protein Kinase MST2, Mouse 2
TBA1A_RAT P68370 CHEMBL4139 Tubulin Alpha-1 Chain, Rat 2
TESK1_HUMAN Q15569 CHEMBL5604 Dual Specificity Testis-specific Protein Kinase 1, Human 2
TNI3K_HUMAN Q59H18 CHEMBL5260 Serine/threonine-protein Kinase TNNI3K, Human 2
TNK1_HUMAN Q13470 CHEMBL5334 Non-receptor Tyrosine-protein Kinase TNK1, Human 2
YES_HUMAN P07947 CHEMBL2073 Tyrosine-protein Kinase YES, Human 2
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 1
ACK1_HUMAN Q07912 CHEMBL4599 Tyrosine Kinase Non-receptor Protein 2, Human 1
ACVR1_HUMAN Q04771 CHEMBL5903 Activin Receptor Type-1, Human 1
ADCK4_HUMAN Q96D53 CHEMBL5753 Uncharacterized AarF Domain-containing Protein Kinase 4, Human 1
ARBK1_HUMAN P25098 CHEMBL4079 G-protein Coupled Receptor Kinase 2, Human 1
ARBK2_HUMAN P35626 CHEMBL1075166 Beta-adrenergic Receptor Kinase 2, Human 1
BLK_MOUSE P16277 CHEMBL3343 Tyrosine-protein Kinase BLK, Mouse 1
BMPR2_HUMAN Q13873 CHEMBL5467 Bone Morphogenetic Protein Receptor Type-2, Human 1
BMR1A_HUMAN P36894 CHEMBL5275 Bone Morphogenetic Protein Receptor Type-1A, Human 1
BMX_HUMAN P51813 CHEMBL3834 Tyrosine-protein Kinase BMX, Human 1
BRSK1_HUMAN Q8TDC3 CHEMBL5650 BR Serine/threonine-protein Kinase 1, Human 1
BRSK2_HUMAN Q8IWQ3 CHEMBL4574 BR Serine/threonine-protein Kinase 2, Human 1
BTK_HUMAN Q06187 CHEMBL5251 Tyrosine-protein Kinase BTK, Human 1
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 1
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 1
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 1
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 1
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 1
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 1
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1
CCL2_HUMAN P13500 CHEMBL1649052 C-C Motif Chemokine 2, Human 1
CCNB_MARGL P15206 CHEMBL4260 G2/mitotic-specific Cyclin B, Margl 1
CDK1_MOUSE P11440 CHEMBL4084 Cyclin-dependent Kinase 1, Mouse 1
CDK6_HUMAN Q00534 CHEMBL2508 Cyclin-dependent Kinase 6, Human 1
CLK3_HUMAN P49761 CHEMBL4226 Dual Specificity Protein Kinase CLK3, Human 1
DCLK1_HUMAN O15075 CHEMBL5683 Serine/threonine-protein Kinase DCLK1, Human 1
DCLK2_HUMAN Q8N568 CHEMBL5519 Serine/threonine-protein Kinase DCLK2, Human 1
DCLK3_HUMAN Q9C098 CHEMBL6123 Serine/threonine-protein Kinase DCLK3, Human 1
E2AK4_HUMAN Q9P2K8 CHEMBL5358 Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human 1
EPHA1_HUMAN P21709 CHEMBL5810 Ephrin Type-A Receptor 1, Human 1
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 1
ERBB4_HUMAN Q15303 CHEMBL3009 Receptor Protein-tyrosine Kinase ErbB-4, Human 1
ERG1_RAT P52020 CHEMBL4241 Squalene Monooxygenase, Rat 1
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1
FGFR1_MOUSE P16092 CHEMBL3960 Fibroblast Growth Factor Receptor 1, Mouse 1
FGR_RAT Q6P6U0 CHEMBL4362 Tyrosine-protein Kinase FGR, Rat 1
GRK4_HUMAN P32298 CHEMBL5861 G Protein-coupled Receptor Kinase 4, Human 1
GRK5_HUMAN P34947 CHEMBL5678 G Protein-coupled Receptor Kinase 5, Human 1
GRK6_HUMAN P43250 CHEMBL6144 G Protein-coupled Receptor Kinase 6, Human 1
GRK7_HUMAN Q8WTQ7 CHEMBL1075133 G Protein-coupled Receptor Kinase 7, Human 1
HIPK1_HUMAN Q86Z02 CHEMBL5427 Homeodomain-interacting Protein Kinase 1, Human 1
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 1
IKKA_HUMAN O15111 CHEMBL3476 Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, Human 1
IKKE_HUMAN Q14164 CHEMBL3529 Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human 1
INSR_MOUSE P15208 CHEMBL3187 Insulin Receptor, Mouse 1
IRAK3_HUMAN Q9Y616 CHEMBL5081 Interleukin-1 Receptor-associated Kinase 3, Human 1
IRAK4_HUMAN Q9NWZ3 CHEMBL3778 Interleukin-1 Receptor-associated Kinase 4, Human 1
JAK1_HUMAN P23458 CHEMBL2835 Tyrosine-protein Kinase JAK1, Human 1
JAK1_MOUSE P52332 CHEMBL2968 Tyrosine-protein Kinase JAK1, Mouse 1
KAPCA_MOUSE P05132 CHEMBL4991 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Mouse 1
KAPCA_RAT P27791 CHEMBL3390 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rat 1
KAPCB_MOUSE P68181 CHEMBL2481 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Mouse 1
KC1A_MOUSE Q8BK63 CHEMBL5148 Casein Kinase I Alpha, Mouse 1
KC1D_MOUSE Q9DC28 CHEMBL5175 Casein Kinase I Delta, Mouse 1
KC1E_MOUSE Q9JMK2 CHEMBL5140 Casein Kinase I Epsilon, Mouse 1
KC1G1_MOUSE Q8BTH8 CHEMBL4455 Casein Kinase I Gamma 1, Mouse 1
KC1G3_HUMAN Q9Y6M4 CHEMBL5084 Casein Kinase I Isoform Gamma-3, Human 1
KCC1G_HUMAN Q96NX5 CHEMBL5258 CaM Kinase I Gamma, Human 1
KCC2A_RAT P11275 CHEMBL2359 CaM Kinase II Alpha, Rat 1
KGP1_BOVIN P00516 CHEMBL3183 CGMP-dependent Protein Kinase 1 Alpha, Bovin 1
KSYK_RAT Q64725 CHEMBL4364 Tyrosine-protein Kinase SYK, Rat 1
LCK_MOUSE P06240 CHEMBL2480 Tyrosine-protein Kinase LCK, Mouse 1
LIMK1_HUMAN P53667 CHEMBL3836 LIM Domain Kinase 1, Human 1
LYN_RAT Q07014 CHEMBL4363 Tyrosine-protein Kinase Lyn, Rat 1
M3K10_HUMAN Q02779 CHEMBL2873 Mitogen-activated Protein Kinase Kinase Kinase 10, Human 1
M3K11_HUMAN Q16584 CHEMBL2708 Mitogen-activated Protein Kinase Kinase Kinase 11, Human 1
M3K14_HUMAN Q99558 CHEMBL5888 Mitogen-activated Protein Kinase Kinase Kinase 14, Human 1
M3K4_HUMAN Q9Y6R4 CHEMBL4853 Mitogen-activated Protein Kinase Kinase Kinase 4, Human 1
M3K5_HUMAN Q99683 CHEMBL5285 Mitogen-activated Protein Kinase Kinase Kinase 5, Human 1
M3K7_HUMAN O43318 CHEMBL5776 Mitogen-activated Protein Kinase Kinase Kinase 7, Human 1
MARK1_HUMAN Q9P0L2 CHEMBL5940 Serine/threonine-protein Kinase MARK1, Human 1
MARK3_HUMAN P27448 CHEMBL5600 Serine/threonine-protein Kinase C-TAK1, Human 1
MARK4_HUMAN Q96L34 CHEMBL5754 MAP/microtubule Affinity-regulating Kinase 4, Human 1
MINK1_HUMAN Q8N4C8 CHEMBL5518 Misshapen-like Kinase 1, Human 1
MK07_HUMAN Q13164 CHEMBL5332 Mitogen-activated Protein Kinase 7, Human 1
MP2K3_HUMAN P46734 CHEMBL2109 Dual Specificity Mitogen-activated Protein Kinase Kinase 3, Human 1
MP2K6_HUMAN P52564 CHEMBL2171 Dual Specificity Mitogen-activated Protein Kinase Kinase 6, Human 1
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 1
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 1
MYLK3_HUMAN Q32MK0 CHEMBL4627 Myosin Light Chain Kinase, Human 1
MYLK4_HUMAN Q86YV6 CHEMBL5426 Myosin Light Chain Kinase Family Member 4, Human 1
MYLK_CHICK P11799 CHEMBL3062 Myosin Light Chain Kinase, Smooth Muscle, Chick 1
NEK1_HUMAN Q96PY6 CHEMBL5855 Serine/threonine-protein Kinase Nek1, Human 1
NEK2_HUMAN P51955 CHEMBL3835 Serine/threonine-protein Kinase NEK2, Human 1
NEK7_HUMAN Q8TDX7 CHEMBL4849 Serine/threonine-protein Kinase NEK7, Human 1
NEK9_HUMAN Q8TD19 CHEMBL5257 Serine/threonine-protein Kinase NEK9, Human 1
NOX4_HUMAN Q9NPH5 CHEMBL1250375 NADPH Oxidase 4, Human 1
P3C2B_HUMAN O00750 CHEMBL5554 Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Beta Polypeptide, Human 1
PAK1_HUMAN Q13153 CHEMBL4600 Serine/threonine-protein Kinase PAK 1, Human 1
PAK2_HUMAN Q13177 CHEMBL4487 Serine/threonine-protein Kinase PAK 2, Human 1
PAK3_HUMAN O75914 CHEMBL2999 Serine/threonine-protein Kinase PAK 3, Human 1
PAK6_HUMAN Q9NQU5 CHEMBL4311 Serine/threonine-protein Kinase PAK6, Human 1
PAK7_HUMAN Q9P286 CHEMBL4524 Serine/threonine-protein Kinase PAK7, Human 1
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 1
PGFRA_MOUSE P26618 CHEMBL3466 Platelet-derived Growth Factor Receptor Alpha, Mouse 1
PGFRB_MOUSE P05622 CHEMBL2749 Platelet-derived Growth Factor Receptor Beta, Mouse 1
PK3CA_BOVIN P32871 CHEMBL2498 PI3-kinase P110-alpha Subunit, Bovin 1
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 1
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 1
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 1
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 1
PLK2_HUMAN Q9NYY3 CHEMBL5938 Serine/threonine-protein Kinase PLK2, Human 1
PRKX_HUMAN P51817 CHEMBL5818 Serine/threonine-protein Kinase PRKX, Human 1
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 1
Q8MMZ8_EIMTE Q8MMZ8 CHEMBL5036 CGMP-dependent Protein Kinase, Eimte 1
Q9BJF5_TOXGO Q9BJF5 CHEMBL1781862 Calmodulin-domain Protein Kinase 1, Toxgo 1
RIOK3_HUMAN O14730 CHEMBL5659 Serine/threonine-protein Kinase RIO3, Human 1
RK_HUMAN Q15835 CHEMBL5607 Rhodopsin Kinase, Human 1
SIK2_HUMAN Q9H0K1 CHEMBL5699 Serine/threonine-protein Kinase SIK2, Human 1
SRC_CHICK P00523 CHEMBL3655 Tyrosine-protein Kinase SRC, Chick 1
SRPK1_HUMAN Q96SB4 CHEMBL4375 Serine/threonine-protein Kinase SRPK1, Human 1
SRPK2_HUMAN P78362 CHEMBL5668 Serine/threonine-protein Kinase SRPK2, Human 1
ST17A_HUMAN Q9UEE5 CHEMBL4525 Serine/threonine-protein Kinase 17A, Human 1
ST17B_HUMAN O94768 CHEMBL3980 Serine/threonine-protein Kinase 17B, Human 1
ST32C_HUMAN Q86UX6 CHEMBL5405 Serine/threonine-protein Kinase 32C, Human 1
ST38L_HUMAN Q9Y2H1 CHEMBL4851 Serine/threonine-protein Kinase 38-like, Human 1
STK11_HUMAN Q15831 CHEMBL5606 Serine/threonine-protein Kinase 11, Human 1
STK16_HUMAN O75716 CHEMBL3938 Serine/threonine-protein Kinase 16, Human 1
STK24_HUMAN Q9Y6E0 CHEMBL5082 Serine/threonine-protein Kinase 24, Human 1
SYK_HUMAN Q15046 CHEMBL5575 Lysyl-tRNA Synthetase, Human 1
TAB1_HUMAN Q15750 CHEMBL5605 Mitogen-activated Protein Kinase Kinase Kinase 7-interacting Protein 1, Human 1
TEC_HUMAN P42680 CHEMBL4246 Tyrosine-protein Kinase TEC, Human 1
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 1
TGFR2_HUMAN P37173 CHEMBL4267 TGF-beta Receptor Type II, Human 1
TLK1_HUMAN Q9UKI8 CHEMBL5388 Serine/threonine-protein Kinase Tousled-like 1, Human 1
TLK2_HUMAN Q86UE8 CHEMBL5404 Serine/threonine-protein Kinase Tousled-like 2, Human 1
TSSK1_HUMAN Q9BXA7 CHEMBL6003 Testis-specific Serine/threonine-protein Kinase 1, Human 1
TXK_HUMAN P42681 CHEMBL4367 Tyrosine-protein Kinase TXK, Human 1
TYRO3_HUMAN Q06418 CHEMBL5314 Tyrosine-protein Kinase Receptor TYRO3, Human 1
ULK3_MOUSE Q3U3Q1 CHEMBL3832 ULK3 Kinase, Mouse 1
VGFR1_MOUSE P35969 CHEMBL3516 Vascular Endothelial Growth Factor Receptor 1, Mouse 1
VGFR3_MOUSE P35917 CHEMBL4758 Vascular Endothelial Growth Factor Receptor 3, Mouse 1
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 1
ZAP70_HUMAN P43403 CHEMBL2803 Tyrosine-protein Kinase ZAP-70, Human 1

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