UCSF

Platelet-derived Growth Factor Receptor Alpha, Rat (47 Compounds)

Swissprot:
PGFRA_RAT
Stitch:
PGFRA_RAT
UniProt:
P20786
ChEMBL:
CHEMBL2513
PDB:
Pdgfra

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 47 6 0 1
Binding ≤ 1μM 36 4 0 0
Functional ≤ 10μM 36 8 1 1

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 410 47 19 27
PGFRA_MOUSE P26618 CHEMBL3466 Platelet-derived Growth Factor Receptor Alpha, Mouse 99 16 1 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PGFRA-1-E Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 2), Eukaryotic 348 45 16 25
PGFRA-2-E Platelet-derived Growth Factor Receptor Alpha (cluster #2 Of 2), Eukaryotic 168 17 3 3
Uniprot Swissprot Chembl Description Number Shared
PGFRB_RAT Q05030 CHEMBL4125 Platelet-derived Growth Factor Receptor Beta, Rat 45
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 31
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 31
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 29
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 28
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 26
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 26
Z80742 Z80742 CHEMBL614657 C6 (Glioma Cells) 26
PGFRB_MOUSE P05622 CHEMBL2749 Platelet-derived Growth Factor Receptor Beta, Mouse 22
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 20
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 17
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 14
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 14
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 13
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 11
PGFRA_MOUSE P26618 CHEMBL3466 Platelet-derived Growth Factor Receptor Alpha, Mouse 10
SRC_CHICK P00523 CHEMBL3655 Tyrosine-protein Kinase SRC, Chick 8
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 7
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 7
Z80951 Z80951 CHEMBL614822 NIH3T3 (Fibroblasts) 7
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 6
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 6
CSK21_MOUSE Q60737 CHEMBL3537 Casein Kinase II Alpha, Mouse 6
FGFR1_MOUSE P16092 CHEMBL3960 Fibroblast Growth Factor Receptor 1, Mouse 6
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 6
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 6
VGFR2_MOUSE P35918 CHEMBL3337 Vascular Endothelial Growth Factor Receptor 2, Mouse 6
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 6
FGFR2_MOUSE P21803 CHEMBL3648 Fibroblast Growth Factor Receptor 2, Mouse 5
FGFR3_MOUSE Q61851 CHEMBL4066 Fibroblast Growth Factor Receptor 3, Mouse 5
FGFR4_MOUSE Q03142 CHEMBL3839 Fibroblast Growth Factor Receptor 4, Mouse 5
SRC_MOUSE P05480 CHEMBL3074 Tyrosine-protein Kinase SRC, Mouse 5
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 4
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 4
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 4
KC1G1_HUMAN Q9HCP0 CHEMBL2426 Casein Kinase I Gamma 1, Human 4
KC1G2_HUMAN P78368 CHEMBL2543 Casein Kinase I Gamma 2, Human 4
MK01_HUMAN P28482 CHEMBL4040 MAP Kinase ERK2, Human 3
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 3
Z104300 Z104300 CHEMBL1907606 Mitogen-activated Protein Kinase; ERK1/ERK2 3
Z80152 Z80152 CHEMBL613510 HCT-8 (Ileocecal Adenocarcinoma) 3
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 3
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 2
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 2
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 2
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 2
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 2
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 2
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 2
CSK22_HUMAN P19784 CHEMBL4070 Casein Kinase II Alpha (prime), Human 2
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 2
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 2
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 2
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 2
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 2
MK03_HUMAN P27361 CHEMBL3385 MAP Kinase ERK1, Human 2
Q95J97_RABIT Q95J97 CHEMBL4885 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rabit 2
ABL2_HUMAN P42684 CHEMBL4014 Tyrosine-protein Kinase ABL2, Human 1
BTK_HUMAN Q06187 CHEMBL5251 Tyrosine-protein Kinase BTK, Human 1
CSK_MOUSE P41241 CHEMBL2333 Tyrosine-protein Kinase CSK, Mouse 1
E2AK2_HUMAN P19525 CHEMBL5785 Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human 1
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
KCC2A_HUMAN Q9UQM7 CHEMBL4147 CaM Kinase II Alpha, Human 1
KCC2B_HUMAN Q13554 CHEMBL4121 CaM Kinase II Beta, Human 1
KCC2D_HUMAN Q13557 CHEMBL2801 CaM Kinase II Delta, Human 1
KCC2G_HUMAN Q13555 CHEMBL3829 CaM Kinase II Gamma, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 1
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 1
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 1
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 1
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 1
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1
Z80036 Z80036 CHEMBL614524 BaF3 (IL-3-dependent Pro-B-cells) 1
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 1
Z80416 Z80416 CHEMBL614630 Rat1 (Fibroblast Cells) 1
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 1
Z81037 Z81037 CHEMBL613967 Human Ovarian Carcinoma Cell Line 1
Z81125 Z81125 CHEMBL613997 KU812 Cell Line 1
Z81328 Z81328 CHEMBL614302 Src-transformed (Fibroblast Cells) 1
ZAP70_HUMAN P43403 CHEMBL2803 Tyrosine-protein Kinase ZAP-70, Human 1