UCSF

Vascular Endothelial Growth Factor Receptor 2, Human (3,357 Compounds)

Swissprot:
VGFR2_HUMAN
Stitch:
VGFR2_HUMAN
UniProt:
P35968
ChEMBL:
CHEMBL279
Reactome:
REACT_228063
REACT_13552
REACT_12473
REACT_12583
REACT_228166
REACT_228024
PDB:
1VR2 (DOCK)
1Y6A (DOCK)
1Y6B (DOCK)
1YWN (DOCK)
2OH4 (DOCK)
2P2H (DOCK)
2P2I (DOCK)
2QU5 (DOCK)
2QU6 (DOCK)
2RL5 (DOCK)
2X1W (DOCK)
2X1X (DOCK)
2XIR (DOCK)
3B8Q (DOCK)
3B8R (DOCK)
3BE2 (DOCK)
3C7Q (DOCK)
3CJF (DOCK)
3CJG (DOCK)
3CP9 (DOCK)
3CPB (DOCK)
3CPC (DOCK)
3DTW (DOCK)
3EFL (DOCK)
3EWH (DOCK)
3KVQ (DOCK)
3S35 (DOCK)
3S36 (DOCK)
3S37 (DOCK)
3VHE (DOCK)
KDR

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 3,357 148 31 64
Binding ≤ 1μM 2,672 111 23 51
Functional ≤ 10μM 455 25 8 12

Reactome Network (6)

Reactome ID Description Species
REACT_228063 EPHA-mediated growth cone collapse Homo sapiens
REACT_13552 Integrin cell surface interactions Homo sapiens
REACT_12473 Neurophilin interactions with VEGF and VEGFR Homo sapiens
REACT_12583 VEGF binds to VEGFR leading to receptor dimerization Homo sapiens
REACT_228166 VEGFA-VEGFR2 Pathway Homo sapiens
REACT_228024 VEGFR2 mediated cell proliferation Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
EPHA1_HUMAN P21709 CHEMBL5810 Ephrin Type-A Receptor 1, Human 7
EPHA2_HUMAN P29317 CHEMBL2068 Ephrin Type-A Receptor 2, Human 21
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin Type-A Receptor 3, Human 13
EPHA4_HUMAN P54764 CHEMBL3988 Ephrin Type-A Receptor 4, Human 8
EPHA5_HUMAN P54756 CHEMBL3987 Ephrin Type-A Receptor 5, Human 8
EPHA6_HUMAN Q9UF33 CHEMBL4526 Ephrin Type-A Receptor 6, Human 13
EPHA7_HUMAN Q15375 CHEMBL4602 Ephrin Type-A Receptor 7, Human 8
EPHA8_HUMAN P29322 CHEMBL4134 Ephrin Type-A Receptor 8, Human 10
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 22
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 40
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 94
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 2
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 6
YES_HUMAN P07947 CHEMBL2073 Tyrosine-protein Kinase YES, Human 42

Neurophilin interactions with VEGF and VEGFR

Uniprot Swissprot Chembl Description Number Shared
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 602

VEGF binds to VEGFR leading to receptor dimerization

Uniprot Swissprot Chembl Description Number Shared
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 602
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 350

VEGFA-VEGFR2 Pathway

Uniprot Swissprot Chembl Description Number Shared
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 22
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 7
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 40
HSPB1_HUMAN P04792 CHEMBL5976 Heat Shock Protein Beta-1, Human 1
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 10
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 8
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 7
MAPK2_HUMAN P49137 CHEMBL2208 MAP Kinase-activated Protein Kinase 2, Human 4
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 6
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 7
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 5
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 113
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 1
PAK2_HUMAN Q13177 CHEMBL4487 Serine/threonine-protein Kinase PAK 2, Human 2
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 118
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 102
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 2
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 6
UFO_HUMAN P30530 CHEMBL4895 Tyrosine-protein Kinase Receptor UFO, Human 17

VEGFR2 mediated cell proliferation

Uniprot Swissprot Chembl Description Number Shared
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 18
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 15
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 9
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 5
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 8
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
VGFR2_MOUSE P35918 CHEMBL3337 Vascular Endothelial Growth Factor Receptor 2, Mouse 182 14 5 10
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 534 48 19 28
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 188 39 16 23

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
VGFR2-1-E Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic 3,192 138 30 61
VGFR2-2-E Vascular Endothelial Growth Factor Receptor 2 (cluster #2 Of 2), Eukaryotic 209 12 2 5
Uniprot Swissprot Chembl Description Number Shared
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 600
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 476
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 459
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 408
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 350
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 314
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 311
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 295
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 232
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 204
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 196
HCK_HUMAN P08631 CHEMBL3234 Tyrosine-protein Kinase HCK, Human 195
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 179
EPHB4_HUMAN P54760 CHEMBL5147 Ephrin Type-B Receptor 4, Human 155
VGFR2_MOUSE P35918 CHEMBL3337 Vascular Endothelial Growth Factor Receptor 2, Mouse 144
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 140
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 131
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 125
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 124
PRKDC_HUMAN P78527 CHEMBL3142 DNA-dependent Protein Kinase, Human 124
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 118
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 113
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 113
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 112
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 102
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 94
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 94
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 93
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 81
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 81
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 64
CSF1R_HUMAN P07333 CHEMBL1844 Macrophage Colony Stimulating Factor Receptor, Human 63
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 61
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 59
RET_HUMAN P07949 CHEMBL2041 Tyrosine-protein Kinase Receptor RET, Human 59
PI4KB_HUMAN Q9UBF8 CHEMBL3268 PI4-kinase Beta Subunit, Human 57
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 55
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 48
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 47
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 42
YES_HUMAN P07947 CHEMBL2073 Tyrosine-protein Kinase YES, Human 42
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 40
RON_HUMAN Q04912 CHEMBL2689 Macrophage-stimulating Protein Receptor, Human 33
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 31
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 29
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 27
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 26
SRC_CHICK P00523 CHEMBL3655 Tyrosine-protein Kinase SRC, Chick 26
KSYK_HUMAN P43405 CHEMBL2599 Tyrosine-protein Kinase SYK, Human 24
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 22
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 22
ACK1_HUMAN Q07912 CHEMBL4599 Tyrosine Kinase Non-receptor Protein 2, Human 21
EPHA2_HUMAN P29317 CHEMBL2068 Ephrin Type-A Receptor 2, Human 21
LCK_MOUSE P06240 CHEMBL2480 Tyrosine-protein Kinase LCK, Mouse 21
PGFRB_MOUSE P05622 CHEMBL2749 Platelet-derived Growth Factor Receptor Beta, Mouse 21
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 21
BLK_HUMAN P51451 CHEMBL2250 Tyrosine-protein Kinase BLK, Human 20
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 20
MK09_HUMAN P45984 CHEMBL4179 C-Jun N-terminal Kinase 2, Human 20
PGFRA_RAT P20786 CHEMBL2513 Platelet-derived Growth Factor Receptor Alpha, Rat 20
STK10_HUMAN O94804 CHEMBL3981 Serine/threonine-protein Kinase 10, Human 20
AURKC_HUMAN Q9UQB9 CHEMBL3935 Serine/threonine-protein Kinase Aurora-C, Human 19
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 19
SLK_HUMAN Q9H2G2 CHEMBL4202 Serine/threonine-protein Kinase 2, Human 19
CHK1_HUMAN O14757 CHEMBL4630 Serine/threonine-protein Kinase Chk1, Human 18
CSK_HUMAN P41240 CHEMBL2634 Tyrosine-protein Kinase CSK, Human 18
DDR1_HUMAN Q08345 CHEMBL5319 Epithelial Discoidin Domain-containing Receptor 1, Human 18
FGR_HUMAN P09769 CHEMBL4454 Tyrosine-protein Kinase FGR, Human 18
FRK_HUMAN P42685 CHEMBL4223 Tyrosine-protein Kinase FRK, Human 18
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 18
M4K5_HUMAN Q9Y4K4 CHEMBL4852 Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human 18
NTRK2_HUMAN Q16620 CHEMBL4898 Neurotrophic Tyrosine Kinase Receptor Type 2, Human 18
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 17
CSK_MOUSE P41241 CHEMBL2333 Tyrosine-protein Kinase CSK, Mouse 17
MERTK_HUMAN Q12866 CHEMBL5331 Proto-oncogene Tyrosine-protein Kinase MER, Human 17
UFO_HUMAN P30530 CHEMBL4895 Tyrosine-protein Kinase Receptor UFO, Human 17
VGFR1_MOUSE P35969 CHEMBL3516 Vascular Endothelial Growth Factor Receptor 1, Mouse 17
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 16
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 15
CTRO_HUMAN O14578 CHEMBL5579 Citron Rho-interacting Kinase, Human 15
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 15
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 15
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 15
KS6A1_HUMAN Q15418 CHEMBL2553 Ribosomal Protein S6 Kinase Alpha 1, Human 15
TYK2_HUMAN P29597 CHEMBL3553 Tyrosine-protein Kinase TYK2, Human 15
ABL2_HUMAN P42684 CHEMBL4014 Tyrosine-protein Kinase ABL2, Human 14
BTK_HUMAN Q06187 CHEMBL5251 Tyrosine-protein Kinase BTK, Human 14
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 14
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 14
M3K9_HUMAN P80192 CHEMBL2872 Mitogen-activated Protein Kinase Kinase Kinase 9, Human 14
M4K4_HUMAN O95819 CHEMBL6166 Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human 14
MKNK1_HUMAN Q9BUB5 CHEMBL4718 MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human 14
MP2K2_HUMAN P36507 CHEMBL2964 Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human 14
PGFRB_RAT Q05030 CHEMBL4125 Platelet-derived Growth Factor Receptor Beta, Rat 14
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 14
TIE1_HUMAN P35590 CHEMBL5274 Tyrosine-protein Kinase Receptor Tie-1, Human 14
Z80742 Z80742 CHEMBL614657 C6 (Glioma Cells) 14
DDR2_HUMAN Q16832 CHEMBL5122 Discoidin Domain-containing Receptor 2, Human 13
E2AK2_HUMAN P19525 CHEMBL5785 Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human 13
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin Type-A Receptor 3, Human 13
EPHA6_HUMAN Q9UF33 CHEMBL4526 Ephrin Type-A Receptor 6, Human 13
GAK_HUMAN O14976 CHEMBL4355 Serine/threonine-protein Kinase GAK, Human 13
HDAC1_HUMAN Q13547 CHEMBL325 Histone Deacetylase 1, Human 13
M4K3_HUMAN Q8IVH8 CHEMBL5432 Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human 13
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 13
NTRK3_HUMAN Q16288 CHEMBL5608 NT-3 Growth Factor Receptor, Human 13
TNIK_HUMAN Q9UKE5 CHEMBL4527 TRAF2- And NCK-interacting Kinase, Human 13
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 13
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 12
CDK16_HUMAN Q00536 CHEMBL4597 Serine/threonine-protein Kinase PCTAIRE-1, Human 12
CDK7_HUMAN P50613 CHEMBL3055 Cyclin-dependent Kinase 7, Human 12
CSK22_HUMAN P19784 CHEMBL4070 Casein Kinase II Alpha (prime), Human 12
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 12
KC1G2_HUMAN P78368 CHEMBL2543 Casein Kinase I Gamma 2, Human 12
M3K11_HUMAN Q16584 CHEMBL2708 Mitogen-activated Protein Kinase Kinase Kinase 11, Human 12
M4K1_HUMAN Q92918 CHEMBL5749 Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human 12
MK01_HUMAN P28482 CHEMBL4040 MAP Kinase ERK2, Human 12
MUSK_HUMAN O15146 CHEMBL5684 Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human 12
SIK2_HUMAN Q9H0K1 CHEMBL5699 Serine/threonine-protein Kinase SIK2, Human 12
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 12
ADA_BOVIN P56658 CHEMBL2966 Adenosine Deaminase, Bovin 11
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 11
DAPK3_HUMAN O43293 CHEMBL2468 Death-associated Protein Kinase 3, Human 11
E2AK4_HUMAN Q9P2K8 CHEMBL5358 Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human 11
EPHB1_HUMAN P54762 CHEMBL5072 Ephrin Type-B Receptor 1, Human 11
KC1G1_HUMAN Q9HCP0 CHEMBL2426 Casein Kinase I Gamma 1, Human 11
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 11
MKNK2_HUMAN Q9HBH9 CHEMBL4204 MAP Kinase Signal-integrating Kinase 2, Human 11
MLTK_HUMAN Q9NYL2 CHEMBL3886 Mixed Lineage Kinase 7, Human 11
MYLK2_HUMAN Q9H1R3 CHEMBL2777 Myosin Light Chain Kinase 2, Human 11
NEK2_HUMAN P51955 CHEMBL3835 Serine/threonine-protein Kinase NEK2, Human 11
STK3_HUMAN Q13188 CHEMBL4708 Serine/threonine-protein Kinase MST2, Human 11
TTK_HUMAN P33981 CHEMBL3983 Dual Specificity Protein Kinase TTK, Human 11
AAPK1_HUMAN Q13131 CHEMBL4045 AMP-activated Protein Kinase, Alpha-1 Subunit, Human 10
ANKK1_HUMAN Q8NFD2 CHEMBL5547 Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human 10
BMX_HUMAN P51813 CHEMBL3834 Tyrosine-protein Kinase BMX, Human 10
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 10
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 10
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 10
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 10
CLK4_HUMAN Q9HAZ1 CHEMBL4203 Dual Specificity Protein Kinase CLK4, Human 10
EPHA8_HUMAN P29322 CHEMBL4134 Ephrin Type-A Receptor 8, Human 10
EPHB2_HUMAN P29323 CHEMBL3290 Ephrin Type-B Receptor 2, Human 10
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 10
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 10
KS6A2_HUMAN Q15349 CHEMBL3906 Ribosomal Protein S6 Kinase Alpha 2, Human 10
KS6A3_HUMAN P51812 CHEMBL2345 Ribosomal Protein S6 Kinase Alpha 3, Human 10
LTK_HUMAN P29376 CHEMBL5627 Leukocyte Tyrosine Kinase Receptor, Human 10
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 10
PHKG1_HUMAN Q16816 CHEMBL4004 Phosphorylase Kinase Gamma Subunit 1, Human 10
RIPK2_HUMAN O43353 CHEMBL5014 Serine/threonine-protein Kinase RIPK2, Human 10
SIK1_HUMAN P57059 CHEMBL6082 Serine/threonine-protein Kinase SIK1, Human 10
AAK1_HUMAN Q2M2I8 CHEMBL3830 Adaptor-associated Kinase, Human 9
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 9
BMP2K_HUMAN Q9NSY1 CHEMBL4522 BMP-2-inducible Protein Kinase, Human 9
CLK2_HUMAN P49760 CHEMBL4225 Dual Specificity Protein Kinase CLK2, Human 9
IRAK3_HUMAN Q9Y616 CHEMBL5081 Interleukin-1 Receptor-associated Kinase 3, Human 9
JAK1_HUMAN P23458 CHEMBL2835 Tyrosine-protein Kinase JAK1, Human 9
KPCD3_HUMAN O94806 CHEMBL2595 Protein Kinase C Nu, Human 9
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 9
KS6A4_HUMAN O75676 CHEMBL3125 Ribosomal Protein S6 Kinase Alpha 4, Human 9
MYLK_HUMAN Q15746 CHEMBL2428 Myosin Light Chain Kinase, Smooth Muscle, Human 9
NUAK1_HUMAN O60285 CHEMBL5784 NUAK Family SNF1-like Kinase 1, Human 9
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase Kinase Gamma Subunit 2, Human 9
RIPK1_HUMAN Q13546 CHEMBL5464 Receptor-interacting Serine/threonine-protein Kinase 1, Human 9
SRMS_HUMAN Q9H3Y6 CHEMBL5703 Tyrosine-protein Kinase Srms, Human 9
ST17A_HUMAN Q9UEE5 CHEMBL4525 Serine/threonine-protein Kinase 17A, Human 9
STK25_HUMAN O00506 CHEMBL5552 Serine/threonine-protein Kinase 25, Human 9
STK33_HUMAN Q9BYT3 CHEMBL6005 Serine/threonine-protein Kinase 33, Human 9
STK4_HUMAN Q13043 CHEMBL4598 Serine/threonine-protein Kinase MST1, Human 9
TNI3K_HUMAN Q59H18 CHEMBL5260 Serine/threonine-protein Kinase TNNI3K, Human 9
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 9
AAKB1_HUMAN Q9Y478 CHEMBL3847 AMP-activated Protein Kinase, Beta-1 Subunit, Human 8
AAKG1_HUMAN P54619 CHEMBL2393 AMP-activated Protein Kinase, Gamma-1 Subunit, Human 8
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 8
DCLK3_HUMAN Q9C098 CHEMBL6123 Serine/threonine-protein Kinase DCLK3, Human 8
EPHA4_HUMAN P54764 CHEMBL3988 Ephrin Type-A Receptor 4, Human 8
EPHA5_HUMAN P54756 CHEMBL3987 Ephrin Type-A Receptor 5, Human 8
EPHA7_HUMAN Q15375 CHEMBL4602 Ephrin Type-A Receptor 7, Human 8
FER_HUMAN P16591 CHEMBL3982 Tyrosine-protein Kinase FER, Human 8
IRAK4_HUMAN Q9NWZ3 CHEMBL3778 Interleukin-1 Receptor-associated Kinase 4, Human 8
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 8
KKCC1_HUMAN Q8N5S9 CHEMBL5256 CaM-kinase Kinase Alpha, Human 8
KKCC2_HUMAN Q96RR4 CHEMBL5284 CaM-kinase Kinase Beta, Human 8
KS6A6_HUMAN Q9UK32 CHEMBL4924 Ribosomal Protein S6 Kinase Alpha 6, Human 8
KS6B1_HUMAN P23443 CHEMBL4501 Ribosomal Protein S6 Kinase 1, Human 8
M3K10_HUMAN Q02779 CHEMBL2873 Mitogen-activated Protein Kinase Kinase Kinase 10, Human 8
MARK1_HUMAN Q9P0L2 CHEMBL5940 Serine/threonine-protein Kinase MARK1, Human 8
MARK3_HUMAN P27448 CHEMBL5600 Serine/threonine-protein Kinase C-TAK1, Human 8
MST4_HUMAN Q9P289 CHEMBL5941 Serine/threonine-protein Kinase MST4, Human 8
NUAK2_HUMAN Q9H093 CHEMBL5698 NUAK Family SNF1-like Kinase 2, Human 8
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 8
PI42B_HUMAN P78356 CHEMBL5667 Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta, Human 8
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 8
SRPK1_HUMAN Q96SB4 CHEMBL4375 Serine/threonine-protein Kinase SRPK1, Human 8
ST17B_HUMAN O94768 CHEMBL3980 Serine/threonine-protein Kinase 17B, Human 8
STK24_HUMAN Q9Y6E0 CHEMBL5082 Serine/threonine-protein Kinase 24, Human 8
TNK1_HUMAN Q13470 CHEMBL5334 Non-receptor Tyrosine-protein Kinase TNK1, Human 8
TYRO3_HUMAN Q06418 CHEMBL5314 Tyrosine-protein Kinase Receptor TYRO3, Human 8
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 8
BMPR2_HUMAN Q13873 CHEMBL5467 Bone Morphogenetic Protein Receptor Type-2, Human 7
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 7
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 7
EPHA1_HUMAN P21709 CHEMBL5810 Ephrin Type-A Receptor 1, Human 7
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 7
FES_HUMAN P07332 CHEMBL5455 Tyrosine-protein Kinase FES, Human 7
IKKE_HUMAN Q14164 CHEMBL3529 Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human 7
INSRR_HUMAN P14616 CHEMBL5483 Insulin Receptor-related Protein, Human 7
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 7
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 7
KS6A5_HUMAN O75582 CHEMBL4237 Ribosomal Protein S6 Kinase Alpha 5, Human 7
LATS1_HUMAN O95835 CHEMBL6167 Serine/threonine-protein Kinase LATS1, Human 7
LATS2_HUMAN Q9NRM7 CHEMBL5907 Serine/threonine-protein Kinase LATS2, Human 7
M3K4_HUMAN Q9Y6R4 CHEMBL4853 Mitogen-activated Protein Kinase Kinase Kinase 4, Human 7
MARK2_HUMAN Q7KZI7 CHEMBL3831 MAP/microtubule Affinity-regulating Kinase 2, Human 7
MARK4_HUMAN Q96L34 CHEMBL5754 MAP/microtubule Affinity-regulating Kinase 4, Human 7
MELK_HUMAN Q14680 CHEMBL4578 Maternal Embryonic Leucine Zipper Kinase, Human 7
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 7
MK15_HUMAN Q8TD08 CHEMBL5198 Mitogen-activated Protein Kinase 15, Human 7
MYLK_CHICK P11799 CHEMBL3062 Myosin Light Chain Kinase, Smooth Muscle, Chick 7
PAK3_HUMAN O75914 CHEMBL2999 Serine/threonine-protein Kinase PAK 3, Human 7
PI51A_HUMAN Q99755 CHEMBL5969 Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha, Human 7
PLK3_HUMAN Q9H4B4 CHEMBL4897 Serine/threonine-protein Kinase PLK3, Human 7
PTK6_HUMAN Q13882 CHEMBL4601 Tyrosine-protein Kinase BRK, Human 7
RIOK1_HUMAN Q9BRS2 CHEMBL5975 Serine/threonine-protein Kinase RIO1, Human 7
RIOK3_HUMAN O14730 CHEMBL5659 Serine/threonine-protein Kinase RIO3, Human 7
STK16_HUMAN O75716 CHEMBL3938 Serine/threonine-protein Kinase 16, Human 7
STK36_HUMAN Q9NRP7 CHEMBL4312 Serine/threonine-protein Kinase 36, Human 7
TXK_HUMAN P42681 CHEMBL4367 Tyrosine-protein Kinase TXK, Human 7
ZAP70_HUMAN P43403 CHEMBL2803 Tyrosine-protein Kinase ZAP-70, Human 7
ACVR1_HUMAN Q04771 CHEMBL5903 Activin Receptor Type-1, Human 6
CD11A_HUMAN Q9UQ88 CHEMBL5416 PITSLRE Serine/threonine-protein Kinase CDC2L2, Human 6
CD11B_HUMAN P21127 CHEMBL5808 PITSLRE Serine/threonine-protein Kinase CDC2L1, Human 6
CDK17_HUMAN Q00537 CHEMBL5790 Serine/threonine-protein Kinase PCTAIRE-2, Human 6
CDK19_HUMAN Q9BWU1 CHEMBL6002 Cell Division Cycle 2-like Protein Kinase 6, Human 6
CDK1_MOUSE P11440 CHEMBL4084 Cyclin-dependent Kinase 1, Mouse 6
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 6
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 6
KCC1A_HUMAN Q14012 CHEMBL2493 CaM Kinase I Alpha, Human 6
KCC1D_HUMAN Q8IU85 CHEMBL5073 CaM Kinase I Delta, Human 6
KCC2A_HUMAN Q9UQM7 CHEMBL4147 CaM Kinase II Alpha, Human 6
KCC2B_HUMAN Q13554 CHEMBL4121 CaM Kinase II Beta, Human 6
KCC2D_HUMAN Q13557 CHEMBL2801 CaM Kinase II Delta, Human 6
KCC2G_HUMAN Q13555 CHEMBL3829 CaM Kinase II Gamma, Human 6
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 6
LIMK1_HUMAN P53667 CHEMBL3836 LIM Domain Kinase 1, Human 6
LIMK2_HUMAN P53671 CHEMBL5932 LIM Domain Kinase 2, Human 6
M3K7_HUMAN O43318 CHEMBL5776 Mitogen-activated Protein Kinase Kinase Kinase 7, Human 6
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 6
MP2K6_HUMAN P52564 CHEMBL2171 Dual Specificity Mitogen-activated Protein Kinase Kinase 6, Human 6
MYLK4_HUMAN Q86YV6 CHEMBL5426 Myosin Light Chain Kinase Family Member 4, Human 6
NLK_HUMAN Q9UBE8 CHEMBL5364 Serine/threonine Protein Kinase NLK, Human 6
PAK4_HUMAN O96013 CHEMBL4482 Serine/threonine-protein Kinase PAK 4, Human 6
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 6
PKN1_HUMAN Q16512 CHEMBL3384 Protein Kinase N1, Human 6
PKN2_HUMAN Q16513 CHEMBL3032 Protein Kinase N2, Human 6
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 6
ROS1_HUMAN P08922 CHEMBL5568 Proto-oncogene Tyrosine-protein Kinase ROS, Human 6
SRPK2_HUMAN P78362 CHEMBL5668 Serine/threonine-protein Kinase SRPK2, Human 6
STK11_HUMAN Q15831 CHEMBL5606 Serine/threonine-protein Kinase 11, Human 6
TBA1A_RAT P68370 CHEMBL4139 Tubulin Alpha-1 Chain, Rat 6
TESK1_HUMAN Q15569 CHEMBL5604 Dual Specificity Testis-specific Protein Kinase 1, Human 6
TLK2_HUMAN Q86UE8 CHEMBL5404 Serine/threonine-protein Kinase Tousled-like 2, Human 6
BRSK1_HUMAN Q8TDC3 CHEMBL5650 BR Serine/threonine-protein Kinase 1, Human 5
BRSK2_HUMAN Q8IWQ3 CHEMBL4574 BR Serine/threonine-protein Kinase 2, Human 5
CDK14_HUMAN O94921 CHEMBL6162 Serine/threonine-protein Kinase PFTAIRE-1, Human 5
CDK8_HUMAN P49336 CHEMBL5719 Cell Division Protein Kinase 8, Human 5
CDK9_HUMAN P50750 CHEMBL3116 Cyclin-dependent Kinase 9, Human 5
DCLK1_HUMAN O15075 CHEMBL5683 Serine/threonine-protein Kinase DCLK1, Human 5
DMPK_HUMAN Q09013 CHEMBL5320 Myotonin-protein Kinase, Human 5
DYR1B_HUMAN Q9Y463 CHEMBL5543 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human 5
ERBB4_HUMAN Q15303 CHEMBL3009 Receptor Protein-tyrosine Kinase ErbB-4, Human 5
HDAC6_HUMAN Q9UBN7 CHEMBL1865 Histone Deacetylase 6, Human 5
KC1AL_HUMAN Q8N752 CHEMBL5520 Casein Kinase I Isoform Alpha-like, Human 5
KC1G3_HUMAN Q9Y6M4 CHEMBL5084 Casein Kinase I Isoform Gamma-3, Human 5
KCC1G_HUMAN Q96NX5 CHEMBL5258 CaM Kinase I Gamma, Human 5
KCC4_HUMAN Q16566 CHEMBL2494 CaM Kinase IV, Human 5
KPCD2_HUMAN Q9BZL6 CHEMBL4900 Serine/threonine-protein Kinase D2, Human 5
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 5
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 5
MP2K4_HUMAN P45985 CHEMBL2897 Dual Specificity Mitogen-activated Protein Kinase Kinase 4, Human 5
NEK5_HUMAN Q6P3R8 CHEMBL5044 Serine/threonine-protein Kinase Nek5, Human 5
NEK7_HUMAN Q8TDX7 CHEMBL4849 Serine/threonine-protein Kinase NEK7, Human 5
PIM3_HUMAN Q86V86 CHEMBL5407 Serine/threonine-protein Kinase PIM3, Human 5
Q95J97_RABIT Q95J97 CHEMBL4885 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rabit 5
ST38L_HUMAN Q9Y2H1 CHEMBL4851 Serine/threonine-protein Kinase 38-like, Human 5
TLK1_HUMAN Q9UKI8 CHEMBL5388 Serine/threonine-protein Kinase Tousled-like 1, Human 5
AVR2B_HUMAN Q13705 CHEMBL5466 Activin Receptor Type-2B, Human 4
CCND1_HUMAN P24385 CHEMBL3610 G1/S-specific Cyclin D1, Human 4
CDK18_HUMAN Q07002 CHEMBL5316 Serine/threonine-protein Kinase PCTAIRE-3, Human 4
CLK3_HUMAN P49761 CHEMBL4226 Dual Specificity Protein Kinase CLK3, Human 4
DAPK1_HUMAN P53355 CHEMBL2558 Death-associated Protein Kinase 1, Human 4
DAPK2_HUMAN Q9UIK4 CHEMBL3123 Death-associated Protein Kinase 2, Human 4
EPHB6_HUMAN O15197 CHEMBL5836 Ephrin Type-B Receptor 6, Human 4
HIPK4_HUMAN Q8NE63 CHEMBL1075167 Homeodomain-interacting Protein Kinase 4, Human 4
IKKA_HUMAN O15111 CHEMBL3476 Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, Human 4
IKKB_HUMAN O14920 CHEMBL1991 Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human 4
KPCG_RAT P63319 CHEMBL3604 Protein Kinase C Gamma, Rat 4
KPCI_HUMAN P41743 CHEMBL2598 Protein Kinase C Iota, Human 4
MAPK2_HUMAN P49137 CHEMBL2208 MAP Kinase-activated Protein Kinase 2, Human 4
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 4
MRCKB_HUMAN Q9Y5S2 CHEMBL5052 Serine/threonine-protein Kinase MRCK Beta, Human 4
MRCKG_HUMAN Q6DT37 CHEMBL5615 Serine/threonine-protein Kinase MRCK Gamma, Human 4
PAK1_HUMAN Q13153 CHEMBL4600 Serine/threonine-protein Kinase PAK 1, Human 4
PAK7_HUMAN Q9P286 CHEMBL4524 Serine/threonine-protein Kinase PAK7, Human 4
PGFRA_MOUSE P26618 CHEMBL3466 Platelet-derived Growth Factor Receptor Alpha, Mouse 4
ULK3_MOUSE Q3U3Q1 CHEMBL3832 ULK3 Kinase, Mouse 4
Z104300 Z104300 CHEMBL1907606 Mitogen-activated Protein Kinase; ERK1/ERK2 4
ACVL1_HUMAN P37023 CHEMBL5311 Serine/threonine-protein Kinase Receptor R3, Human 3
ADCK3_HUMAN Q8NI60 CHEMBL5550 Chaperone Activity Of Bc1 Complex-like, Mitochondrial, Human 3
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 3
BLK_MOUSE P16277 CHEMBL3343 Tyrosine-protein Kinase BLK, Mouse 3
BMP4_HUMAN P12644 CHEMBL5350 Bone Morphogenetic Protein 4, Human 3
CDK3_HUMAN Q00526 CHEMBL4442 Cyclin-dependent Kinase 3, Human 3
CDKL2_HUMAN Q92772 CHEMBL5728 Cyclin-dependent Kinase-like 2, Human 3
DCLK2_HUMAN Q8N568 CHEMBL5519 Serine/threonine-protein Kinase DCLK2, Human 3
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 3
EPHB3_HUMAN P54753 CHEMBL4901 Ephrin Type-B Receptor 3, Human 3
FGFR1_MOUSE P16092 CHEMBL3960 Fibroblast Growth Factor Receptor 1, Mouse 3
KPCA_RAT P05696 CHEMBL2855 Protein Kinase C Alpha, Rat 3
KPCB_RAT P68403 CHEMBL3020 Protein Kinase C Beta, Rat 3
KPCD_RAT P09215 CHEMBL3633 Protein Kinase C Delta, Rat 3
KPCE_RAT P09216 CHEMBL3424 Protein Kinase C Epsilon, Rat 3
KPCL_RAT Q64617 CHEMBL3990 Protein Kinase C Eta, Rat 3
KPCT_RAT Q9WTQ0 CHEMBL4563 Protein Kinase C Theta, Rat 3
KPCZ_RAT P09217 CHEMBL5379 Protein Kinase C Zeta, Rat 3
MAPK5_HUMAN Q8IW41 CHEMBL3094 MAP Kinase-activated Protein Kinase 5, Human 3
MK06_HUMAN Q16659 CHEMBL5121 Mitogen-activated Protein Kinase 6, Human 3
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 3
MYO3B_HUMAN Q8WXR4 CHEMBL5654 Myosin-IIIB, Human 3
PAK6_HUMAN Q9NQU5 CHEMBL4311 Serine/threonine-protein Kinase PAK6, Human 3
ST32B_HUMAN Q9NY57 CHEMBL5912 Serine/threonine-protein Kinase 32B, Human 3
STK3_MOUSE Q9JI10 CHEMBL4310 Serine/threonine-protein Kinase MST2, Mouse 3
SYK_HUMAN Q15046 CHEMBL5575 Lysyl-tRNA Synthetase, Human 3
TEC_HUMAN P42680 CHEMBL4246 Tyrosine-protein Kinase TEC, Human 3
YSK4_HUMAN Q56UN5 CHEMBL6191 SPS1/STE20-related Protein Kinase YSK4, Human 3
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 3
ACV1B_HUMAN P36896 CHEMBL5310 Activin Receptor Type-1B, Human 2
ADCK4_HUMAN Q96D53 CHEMBL5753 Uncharacterized AarF Domain-containing Protein Kinase 4, Human 2
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 2
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 2
AVR2A_HUMAN P27037 CHEMBL5616 Activin Receptor Type-2A, Human 2
CDK6_HUMAN Q00534 CHEMBL2508 Cyclin-dependent Kinase 6, Human 2
CHK2_HUMAN O96017 CHEMBL2527 Serine/threonine-protein Kinase Chk2, Human 2
CSK21_MOUSE Q60737 CHEMBL3537 Casein Kinase II Alpha, Mouse 2
DLK1_HUMAN P80370 CHEMBL5671 Protein Delta Homolog 1, Human 2
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 2
DYR_MOUSE P00375 CHEMBL4564 Dihydrofolate Reductase, Mouse 2
DYR_RAT Q920D2 CHEMBL2363 Dihydrofolate Reductase, Rat 2
F16P1_HUMAN P09467 CHEMBL3975 Fructose-1,6-bisphosphatase, Human 2
GSK3B_RAT P18266 CHEMBL3669 Glycogen Synthase Kinase-3 Beta, Rat 2
HGF_HUMAN P14210 CHEMBL5479 Hepatocyte Growth Factor, Human 2
HIPK1_HUMAN Q86Z02 CHEMBL5427 Homeodomain-interacting Protein Kinase 1, Human 2
HIPK2_HUMAN Q9H2X6 CHEMBL4576 Homeodomain-interacting Protein Kinase 2, Human 2
HIPK3_HUMAN Q9H422 CHEMBL4577 Homeodomain-interacting Protein Kinase 3, Human 2
IGF1R_MOUSE Q60751 CHEMBL5381 Insulin-like Growth Factor 1 Receptor, Mouse 2
IRAK1_HUMAN P51617 CHEMBL3357 Interleukin-1 Receptor-associated Kinase 1, Human 2
M3K5_HUMAN Q99683 CHEMBL5285 Mitogen-activated Protein Kinase Kinase Kinase 5, Human 2
MINK1_HUMAN Q8N4C8 CHEMBL5518 Misshapen-like Kinase 1, Human 2
MK03_HUMAN P27361 CHEMBL3385 MAP Kinase ERK1, Human 2
MK04_HUMAN P31152 CHEMBL5759 Mitogen-activated Protein Kinase 4, Human 2
MK07_HUMAN Q13164 CHEMBL5332 Mitogen-activated Protein Kinase 7, Human 2
MP2K3_HUMAN P46734 CHEMBL2109 Dual Specificity Mitogen-activated Protein Kinase Kinase 3, Human 2
MYO3A_HUMAN Q8NEV4 CHEMBL5546 Myosin IIIA, Human 2
NEK1_HUMAN Q96PY6 CHEMBL5855 Serine/threonine-protein Kinase Nek1, Human 2
NEK9_HUMAN Q8TD19 CHEMBL5257 Serine/threonine-protein Kinase NEK9, Human 2
PAK2_HUMAN Q13177 CHEMBL4487 Serine/threonine-protein Kinase PAK 2, Human 2
PIM2_HUMAN Q9P1W9 CHEMBL4523 Serine/threonine-protein Kinase PIM2, Human 2
PLK2_HUMAN Q9NYY3 CHEMBL5938 Serine/threonine-protein Kinase PLK2, Human 2
PMYT1_HUMAN Q99640 CHEMBL3984 Tyrosine- And Threonine-specific Cdc2-inhibitory Kinase, Human 2
Q9BJF5_TOXGO Q9BJF5 CHEMBL1781862 Calmodulin-domain Protein Kinase 1, Toxgo 2
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 2
TAB1_HUMAN Q15750 CHEMBL5605 Mitogen-activated Protein Kinase Kinase Kinase 7-interacting Protein 1, Human 2
TAOK1_HUMAN Q7L7X3 CHEMBL5261 Serine/threonine-protein Kinase TAO1, Human 2
TAOK3_HUMAN Q9H2K8 CHEMBL5701 Serine/threonine-protein Kinase TAO3, Human 2
TGFR2_HUMAN P37173 CHEMBL4267 TGF-beta Receptor Type II, Human 2
TSSK1_HUMAN Q9BXA7 CHEMBL6003 Testis-specific Serine/threonine-protein Kinase 1, Human 2
Z104299 Z104299 CHEMBL1907605 Cyclin-dependent Kinase 2/cyclin E1 2
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 2
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 1
ABL1_MOUSE P00520 CHEMBL3099 Tyrosine-protein Kinase ABL, Mouse 1
ADA_HUMAN P00813 CHEMBL1910 Adenosine Deaminase, Human 1
AKIP_HUMAN Q9NWT8 CHEMBL5910 Aurora Kinase A-interacting Protein, Human 1
ALK_MOUSE P97793 CHEMBL5771 ALK Tyrosine Kinase Receptor, Mouse 1
BMR1A_HUMAN P36894 CHEMBL5275 Bone Morphogenetic Protein Receptor Type-1A, Human 1
BRD4_HUMAN O60885 CHEMBL1163125 Bromodomain-containing Protein 4, Human 1
CCND3_HUMAN P30281 CHEMBL2422 G1/S-specific Cyclin D3, Human 1
CCNH_HUMAN P51946 CHEMBL2165 Cyclin H, Human 1
CCNT1_HUMAN O60563 CHEMBL2108 Cyclin T1, Human 1
CDC7_HUMAN O00311 CHEMBL5443 Cell Division Cycle 7-related Protein Kinase, Human 1
CDK15_HUMAN Q96Q40 CHEMBL5856 Serine/threonine-protein Kinase PFTAIRE-2, Human 1
CDKL3_HUMAN Q8IVW4 CHEMBL1163117 Cyclin-dependent Kinase-like 3, Human 1
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 1
CSK21_RAT P19139 CHEMBL2661 Casein Kinase II Alpha, Rat 1
CSK2B_RAT P67874 CHEMBL2463 Casein Kinase II Beta, Rat 1
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 1
DYRK2_HUMAN Q92630 CHEMBL4376 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 2, Human 1
ERN1_HUMAN O75460 CHEMBL1163101 Serine/threonine-protein Kinase/endoribonuclease IRE1, Human 1
F16P1_PIG P00636 CHEMBL2263 Fructose-1,6-bisphosphatase, Pig 1
GRK4_HUMAN P32298 CHEMBL5861 G Protein-coupled Receptor Kinase 4, Human 1
GRK7_HUMAN Q8WTQ7 CHEMBL1075133 G Protein-coupled Receptor Kinase 7, Human 1
HDA10_HUMAN Q969S8 CHEMBL5103 Histone Deacetylase 10, Human 1
HDAC2_HUMAN Q92769 CHEMBL1937 Histone Deacetylase 2, Human 1
HDAC3_HUMAN O15379 CHEMBL1829 Histone Deacetylase 3, Human 1
HDAC4_HUMAN P56524 CHEMBL3524 Histone Deacetylase 4, Human 1
HDAC5_HUMAN Q9UQL6 CHEMBL2563 Histone Deacetylase 5, Human 1
HDAC7_HUMAN Q8WUI4 CHEMBL2716 Histone Deacetylase 7, Human 1
HDAC8_HUMAN Q9BY41 CHEMBL3192 Histone Deacetylase 8, Human 1
HDAC9_HUMAN Q9UKV0 CHEMBL4145 Histone Deacetylase 9, Human 1
HSPB1_HUMAN P04792 CHEMBL5976 Heat Shock Protein Beta-1, Human 1
ICK_HUMAN Q9UPZ9 CHEMBL1163126 Serine/threonine-protein Kinase ICK, Human 1
INCE_HUMAN Q9NQS7 CHEMBL5177 Inner Centromere Protein, Human 1
INSR_MOUSE P15208 CHEMBL3187 Insulin Receptor, Mouse 1
INSR_RAT P15127 CHEMBL5486 Insulin Receptor, Rat 1
JAK1_MOUSE P52332 CHEMBL2968 Tyrosine-protein Kinase JAK1, Mouse 1
KAP2_BOVIN P00515 CHEMBL3654 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Bovin 1
KAP3_BOVIN P31322 CHEMBL3280 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Bovin 1
KAPCA_BOVIN P00517 CHEMBL2654 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Bovin 1
KAPCA_MOUSE P05132 CHEMBL4991 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Mouse 1
KAPCA_RAT P27791 CHEMBL3390 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rat 1
KAPCB_BOVIN P05131 CHEMBL3279 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Bovin 1
KAPCB_MOUSE P68181 CHEMBL2481 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Mouse 1
KC1A_MOUSE Q8BK63 CHEMBL5148 Casein Kinase I Alpha, Mouse 1
KC1D_MOUSE Q9DC28 CHEMBL5175 Casein Kinase I Delta, Mouse 1
KC1E_MOUSE Q9JMK2 CHEMBL5140 Casein Kinase I Epsilon, Mouse 1
KC1G1_MOUSE Q8BTH8 CHEMBL4455 Casein Kinase I Gamma 1, Mouse 1
KCC2A_MOUSE P11798 CHEMBL3347 CaM Kinase II Alpha, Mouse 1
KCC2A_RAT P11275 CHEMBL2359 CaM Kinase II Alpha, Rat 1
KCC2B_MOUSE P28652 CHEMBL4735 CaM Kinase II Beta, Mouse 1
KCC2G_MOUSE Q923T9 CHEMBL4456 CaM Kinase II Gamma, Mouse 1
KGP1_BOVIN P00516 CHEMBL3183 CGMP-dependent Protein Kinase 1 Alpha, Bovin 1
KGP1_HUMAN Q13976 CHEMBL4273 CGMP-dependent Protein Kinase 1 Beta, Human 1
KGP2_HUMAN Q13237 CHEMBL2896 CGMP-dependent Protein Kinase 2, Human 1
KPB1_HUMAN P46020 CHEMBL2905 Phosphorylase Kinase Alpha M Subunit, Human 1
KPB2_HUMAN P46019 CHEMBL2906 Phosphorylase Kinase Alpha L Subunit, Human 1
KPBB_HUMAN Q93100 CHEMBL3844 Phosphorylase Kinase Beta Subunit, Human 1
KS6B2_HUMAN Q9UBS0 CHEMBL3111 Ribosomal Protein S6 Kinase 2, Human 1
M3K13_HUMAN O43283 CHEMBL1163124 Mitogen-activated Protein Kinase Kinase Kinase 13, Human 1
M3K14_HUMAN Q99558 CHEMBL5888 Mitogen-activated Protein Kinase Kinase Kinase 14, Human 1
M3K15_HUMAN Q6ZN16 CHEMBL1163127 Mitogen-activated Protein Kinase Kinase Kinase 15, Human 1
M3K2_HUMAN Q9Y2U5 CHEMBL5914 Mitogen-activated Protein Kinase Kinase Kinase 2, Human 1
M3K3_HUMAN Q99759 CHEMBL5970 Mitogen-activated Protein Kinase Kinase Kinase 3, Human 1
M3K8_HUMAN P41279 CHEMBL4899 Mitogen-activated Protein Kinase Kinase Kinase 8, Human 1
M4K2_HUMAN Q12851 CHEMBL5330 Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, Human 1
MAST1_HUMAN Q9Y2H9 CHEMBL1163128 Microtubule-associated Serine/threonine-protein Kinase 1, Human 1
MET_MOUSE P16056 CHEMBL5585 Hepatocyte Growth Factor Receptor, Mouse 1
NEK6_HUMAN Q9HC98 CHEMBL4309 Serine/threonine-protein Kinase NEK6, Human 1
NIM1_HUMAN Q8IY84 CHEMBL3542 Serine/threonine-protein Kinase NIM1, Human 1
OXSR1_HUMAN O95747 CHEMBL1163104 Serine/threonine-protein Kinase OSR1, Human 1
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 1
P90584_PLAFA P90584 CHEMBL4090 Protein Kinase Pfmrk, Plafa 1
PRKX_HUMAN P51817 CHEMBL5818 Serine/threonine-protein Kinase PRKX, Human 1
PRP4_HUMAN O43172 CHEMBL1163119 U4/U6 Small Nuclear Ribonucleoprotein Prp4, Human 1
RB_HUMAN P06400 CHEMBL5288 Retinoblastoma-associated Protein, Human 1
RIOK2_HUMAN Q9BVS4 CHEMBL6000 Serine/threonine-protein Kinase RIO2, Human 1
RIPK4_HUMAN P57078 CHEMBL6083 Receptor-interacting Serine/threonine-protein Kinase 4, Human 1
RK_HUMAN Q15835 CHEMBL5607 Rhodopsin Kinase, Human 1
SG110_HUMAN P0C264 CHEMBL5116 Putative Uncharacterized Serine/threonine-protein Kinase SgK110, Human 1
SRPK3_HUMAN Q9UPE1 CHEMBL5415 Serine/threonine-protein Kinase SRPK3, Human 1
ST32C_HUMAN Q86UX6 CHEMBL5405 Serine/threonine-protein Kinase 32C, Human 1
STAT3_HUMAN P40763 CHEMBL4026 Signal Transducer And Activator Of Transcription 3, Human 1
STK35_HUMAN Q8TDR2 CHEMBL5651 Serine/threonine-protein Kinase 35, Human 1
STK38_HUMAN Q15208 CHEMBL1075155 Serine/threonine-protein Kinase 38, Human 1
STK39_HUMAN Q9UEW8 CHEMBL1163108 STE20/SPS1-related Proline-alanine-rich Protein Kinase, Human 1
TBA4A_HUMAN P68366 CHEMBL2070 Tubulin Alpha-1 Chain, Human 1
TBB1_HUMAN Q9H4B7 CHEMBL1915 Tubulin Beta-1 Chain, Human 1
TBK1_HUMAN Q9UHD2 CHEMBL5408 Serine/threonine-protein Kinase TBK1, Human 1
TF65_HUMAN Q04206 CHEMBL5533 Nuclear Factor NF-kappa-B P65 Subunit, Human 1
TNFA_HUMAN P01375 CHEMBL1825 TNF-alpha, Human 1
TNKS2_HUMAN Q9H2K2 CHEMBL6154 Tankyrase-2, Human 1
TPX2_HUMAN Q9ULW0 CHEMBL5389 Targeting Protein For Xklp2, Human 1
ULK1_HUMAN O75385 CHEMBL6006 Serine/threonine-protein Kinase ULK1, Human 1
ULK2_HUMAN Q8IYT8 CHEMBL5435 Serine/threonine-protein Kinase ULK2, Human 1
ULK3_HUMAN Q6PHR2 CHEMBL5047 Serine/threonine-protein Kinase ULK3, Human 1
VGFR3_MOUSE P35917 CHEMBL4758 Vascular Endothelial Growth Factor Receptor 3, Mouse 1
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 1
Z100768 Z100768 CHEMBL613836 TPC1 (Papillary Thyroid Carinoma Cells) 1
Z103205 Z103205 CHEMBL1075390 A431 1
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 1
Z50501 Z50501 CHEMBL613109 Gallus Gallus 1
Z80291 Z80291 CHEMBL614181 MRC5 (Embryonic Lung Fibroblast Cells) 1
Z80902 Z80902 CHEMBL614150 HASMC (Aortic Smooth Muscle Cells) 1
Z81037 Z81037 CHEMBL613967 Human Ovarian Carcinoma Cell Line 1
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 1

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