UCSF

MRC5 (Embryonic Lung Fibroblast Cells) (148 Compounds)

Swissprot:
Z80291
Stitch:
Z80291
UniProt:
Z80291
ChEMBL:
CHEMBL614181

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Functional ≤ 10μM 148 13 9 7
ADME/T ≤ 10μM 123 14 7 8

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z50587 Z50587 CHEMBL372 Homo Sapiens 53
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 30
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 17
Z80583 Z80583 CHEMBL391 Vero (Kidney Cells) 15
Z80076 Z80076 CHEMBL614548 CEM-SS (T-cell Leukemia) 13
Z50466 Z50466 CHEMBL368 Trypanosoma Cruzi 11
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 11
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 8
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 8
Z50418 Z50418 CHEMBL612849 Trypanosoma Brucei 7
Z50530 Z50530 CHEMBL371 Human Herpesvirus 5 7
Z80018 Z80018 CHEMBL613859 A-375 (Malignant Melanoma Cells) 7
Z80902 Z80902 CHEMBL614150 HASMC (Aortic Smooth Muscle Cells) 6
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 6
Z81138 Z81138 CHEMBL613872 ScN2a (Scrapie-infected Neuroblastoma Cells) 6
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 5
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 5
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 4
Z50515 Z50515 CHEMBL370 Human Herpesvirus 2 4
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 4
Z80414 Z80414 CHEMBL614628 Raji (B-lymphoblastic Cells) 4
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 4
Z101794 Z101794 CHEMBL612743 Felid Herpesvirus 1 3
Z50517 Z50517 CHEMBL613123 Human Herpesvirus 5 Strain AD169 3
Z50518 Z50518 CHEMBL613124 Human Herpesvirus 4 3
Z50527 Z50527 CHEMBL613132 Human Herpesvirus 3 3
Z50600 Z50600 CHEMBL613493 Vaccinia Virus 3
Z50602 Z50602 CHEMBL377 Human Herpesvirus 1 3
Z50606 Z50606 CHEMBL613497 Hepatitis B Virus 3
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 3
Z80068 Z80068 CHEMBL614542 CCRF-SB (Lymphoblastic Leukemia Cells) 3
Z80092 Z80092 CHEMBL614031 CHO-K1 (Ovarian Cells) 3
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 3
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 3
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 3
Z80244 Z80244 CHEMBL614335 MDA-MB-468 (Breast Adenocarcinoma) 3
Z80253 Z80253 CHEMBL614342 MEF (Embryonic Fibroblast Cells) 3
Z80285 Z80285 CHEMBL614177 MOLT-4 (Acute T-lymphoblastic Leukemia Cells) 3
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 3
Z80472 Z80472 CHEMBL612542 SiHa (Cervical Squamous Cell Carcinoma) 3
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 3
Z80595 Z80595 CHEMBL612810 WIL2-NS (Lymphoblastoid Cells) 3
Z80942 Z80942 CHEMBL613888 HEL (Embryonic Lung Cells) 3
Z80943 Z80943 CHEMBL614819 HEL 299 3
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 3
TOP1_HUMAN P11387 CHEMBL1781 DNA Topoisomerase I, Human 2
TOP1_MOUSE Q04750 CHEMBL2814 DNA Topoisomerase I, Mouse 2
TOP2A_HUMAN P11388 CHEMBL1806 DNA Topoisomerase II Alpha, Human 2
TOP2A_MOUSE Q01320 CHEMBL3586 DNA Topoisomerase II Alpha, Mouse 2
TOP2B_HUMAN Q02880 CHEMBL3396 DNA Topoisomerase II Beta, Human 2
TOP2B_MOUSE Q64511 CHEMBL5564 DNA Topoisomerase II Beta, Mouse 2
Z101697 Z101697 CHEMBL613332 Camelpox Virus 2
Z103203 Z103203 CHEMBL1075388 A375 2
Z103205 Z103205 CHEMBL1075390 A431 2
Z103219 Z103219 CHEMBL1075404 Ca9-22 2
Z50347 Z50347 CHEMBL361 Saccharomyces Cerevisiae 2
Z50472 Z50472 CHEMBL612888 Toxoplasma Gondii 2
Z50604 Z50604 CHEMBL613495 Murid Herpesvirus 1 2
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 2
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 2
Z80002 Z80002 CHEMBL614075 1A9 (Ovarian Adenocarcinoma Cells) 2
Z80005 Z80005 CHEMBL614077 3T3 (Fibroblast Cells) 2
Z80008 Z80008 CHEMBL612565 5637 (Epithelial Bladder Carcinoma Cells) 2
Z80017 Z80017 CHEMBL614023 A2780cisR (Cisplatin-resistant Ovarian Carcinoma Cells) 2
Z80021 Z80021 CHEMBL614516 A498 (Renal Carcinoma Cells) 2
Z80025 Z80025 CHEMBL614519 ACHN (Renal Adenocarcinoma Cells) 2
Z80026 Z80026 CHEMBL613860 AGS (Gastric Adenocarcinoma Cells) 2
Z80035 Z80035 CHEMBL381 B16 (Melanoma Cells) 2
Z80039 Z80039 CHEMBL614526 BGC-823 (Stomach Adenocarcinoma Cells) 2
Z80052 Z80052 CHEMBL614533 C8166 (Leukemic T-cells) 2
Z80054 Z80054 CHEMBL614058 Caco-2 (Colon Adenocarcinoma Cells) 2
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 2
Z80105 Z80105 CHEMBL613854 COR-L23 (Lung Carcinoma Cells) 2
Z80114 Z80114 CHEMBL614281 Daudi (Burkitts Lymphoma Cells) 2
Z80125 Z80125 CHEMBL613508 DU-145 (Prostate Carcinoma) 2
Z80126 Z80126 CHEMBL614289 DuPro 2
Z80138 Z80138 CHEMBL614036 G-361 (Melanoma Cells) 2
Z80145 Z80145 CHEMBL614045 H69 2
Z80164 Z80164 CHEMBL614580 HT-1080 (Fibrosarcoma Cells) 2
Z80175 Z80175 CHEMBL614585 IMR-32 (Neuroblastoma Cells) 2
Z80178 Z80178 CHEMBL614040 J774.A1 (Macrophage Cells) 2
Z80188 Z80188 CHEMBL614590 KB 3-1 (Cervical Epithelial Carcinoma Cells) 2
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 2
Z80214 Z80214 CHEMBL614317 M14 (Melanoma Cells) 2
Z80227 Z80227 CHEMBL614324 MCF7-ADR (Breast Carcinoma Cells) 2
Z80240 Z80240 CHEMBL614129 MDA-MB-361 2
Z80243 Z80243 CHEMBL614334 MDA-MB-453 (Breast Adenocarcinoma Cells) 2
Z80254 Z80254 CHEMBL614343 MES-SA (Uterine Sarcoma Cells) 2
Z80255 Z80255 CHEMBL613827 MES-SA/DxS (Uterine Sarcoma Cells) 2
Z80267 Z80267 CHEMBL614352 MKN-1 2
Z80269 Z80269 CHEMBL614354 MKN-45 (Gastric Adenocarcinoma Cells) 2
Z80322 Z80322 CHEMBL614135 NCI-H358 (Lung Carcinama Cells) 2
Z80330 Z80330 CHEMBL614197 NCI-N87 2
Z80354 Z80354 CHEMBL614213 OVCAR-3 (Ovarian Adenocarcinoma Cells) 2
Z80364 Z80364 CHEMBL614218 P388/ADR (Lymphoma Cells) 2
Z80367 Z80367 CHEMBL614220 P388/S 2
Z80389 Z80389 CHEMBL614140 PC-14 2
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 2
Z80433 Z80433 CHEMBL614882 RPMI-8226 (Multiple Myeloma Cells) 2
Z80441 Z80441 CHEMBL614889 RXF 944 2
Z80466 Z80466 CHEMBL614907 SF268 2
Z80468 Z80468 CHEMBL614908 SF-295 (Glioblastoma Cells) 2
Z80477 Z80477 CHEMBL614912 SK_HEP1 (Hepatoma Cells) 2
Z80479 Z80479 CHEMBL614914 SK-MEL (Melanoma Cells) 2
Z80481 Z80481 CHEMBL614916 SK-MEL-1 (Metastatic Melanoma Cells) 2
Z80482 Z80482 CHEMBL614917 SK-MEL-2 (Melanoma Cells) 2
Z80485 Z80485 CHEMBL614919 SK-MEL-28 (Melanoma Cells) 2
Z80490 Z80490 CHEMBL614923 SK-MES-1 2
Z80491 Z80491 CHEMBL614163 SK-N-MC (Neuroepithelioma Cells) 2
Z80492 Z80492 CHEMBL614924 SK-N-SH (Neuroblastoma Cells) 2
Z80493 Z80493 CHEMBL614925 SK-OV-3 (Ovarian Carcinoma Cells) 2
Z80495 Z80495 CHEMBL614927 SK-VLB 2
Z80503 Z80503 CHEMBL614931 SNU1 2
Z80509 Z80509 CHEMBL614935 SNU-638 (Gastric Carcinoma Cells) 2
Z80526 Z80526 CHEMBL612544 SW480 (Colon Adenocarcinoma Cells) 2
Z80532 Z80532 CHEMBL614774 T-24 (Bladder Carcinoma Cells) 2
Z80548 Z80548 CHEMBL614245 THP-1 (Acute Monocytic Leukemia Cells) 2
Z80559 Z80559 CHEMBL615021 U251 2
Z80560 Z80560 CHEMBL615022 U-251 (Glioma Cells) 2
Z80563 Z80563 CHEMBL615025 U-373 MG ( Glioblastoma Cells) 2
Z80565 Z80565 CHEMBL614247 U-87 MG (Glioblastoma Cells) 2
Z80574 Z80574 CHEMBL612799 UMUC3 2
Z80581 Z80581 CHEMBL614248 VA13 2
Z80600 Z80600 CHEMBL613533 XF498 (Glioma Cells) 2
Z80608 Z80608 CHEMBL614393 ZR-75-1 (Breast Carcinoma Cells) 2
Z80661 Z80661 CHEMBL614567 A704 (Renal Carcinoma Cells) 2
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 2
Z80697 Z80697 CHEMBL614279 Bel-7402 (Hepatoma Cells) 2
Z80704 Z80704 CHEMBL614358 BJ (Foreskin Fibroblast Cells) 2
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 2
Z80726 Z80726 CHEMBL614367 TRAMP-C1A (Prostate Carcinoma Cells) 2
Z80730 Z80730 CHEMBL614368 C2D Cell Line 2
Z80731 Z80731 CHEMBL613541 C2G Cell Line 2
Z80732 Z80732 CHEMBL614369 TRAMP-C2H (Prostate Carcinoma Cells) 2
Z80735 Z80735 CHEMBL614739 C38 (Colon Carcinoma) 2
Z80768 Z80768 CHEMBL614455 CH1 (Ovarian Carcinoma Cells) 2
Z80784 Z80784 CHEMBL614462 Col2 (Colon Carcinoma Cells) 2
Z80801 Z80801 CHEMBL614151 CRL-7065 Cell Line 2
Z80819 Z80819 CHEMBL614484 J774.2 2
Z80846 Z80846 CHEMBL614493 F460pv8/eto Cell Line 2
Z80852 Z80852 CHEMBL614069 A-431 (Epidermoid Carcinoma Cells) 2
Z80887 Z80887 CHEMBL614802 H2981 Cell Line 2
Z80889 Z80889 CHEMBL614803 NCI-H322M (Non-small Cell Lung Carcinoma Cells) 2
Z80896 Z80896 CHEMBL614805 NCI-H69 (Small Cell Lung Carcinoma Cells) 2
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 2
Z80945 Z80945 CHEMBL614735 HEp-2 (Laryngeal Carcinoma Cells) 2
Z80954 Z80954 CHEMBL614071 HFF (Foreskin Fibroblasts) 2
Z81005 Z81005 CHEMBL614839 HTB-54 Cell Line 2
Z81006 Z81006 CHEMBL612259 Human Breast 401NL Tumor Cell Line 2
Z81017 Z81017 CHEMBL614647 WiDr (Colon Adenocarcinoma Cells) 2
Z81024 Z81024 CHEMBL396 NCI-H460 (Non-small Cell Lung Carcinoma) 2
Z81025 Z81025 CHEMBL613890 Human Lung LXF 529L Tumor Cell Line 2
Z81026 Z81026 CHEMBL614689 Human Lung LXF 629L Tumor Cell Line 2
Z81028 Z81028 CHEMBL613892 Human Melanoma Cell Line 2
Z81034 Z81034 CHEMBL614004 A2780 (Ovarian Carcinoma Cells) 2
Z81043 Z81043 CHEMBL613969 N592 2
Z81054 Z81054 CHEMBL613977 SF-268 (Glioblastoma Cells) 2
Z81101 Z81101 CHEMBL614010 KBM-3 Cell Line 2
Z81102 Z81102 CHEMBL613994 KBM-3/DOX Cell Line 2
Z81133 Z81133 CHEMBL614000 L1210 (1565) 2
Z81134 Z81134 CHEMBL614650 L2987 (Lung Adenocarcinoma Cells) 2
Z81135 Z81135 CHEMBL614793 L6 (Skeletal Muscle Myoblast Cells) 2
Z81160 Z81160 CHEMBL614088 Lewis Lung Carcinoma Cell Line 2
Z81164 Z81164 CHEMBL614091 LL Cell Line 2
Z81167 Z81167 CHEMBL614093 LLTC Cell Line 2
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 2
Z81184 Z81184 CHEMBL614096 LOX IMVI (Melanoma Cells) 2
Z81201 Z81201 CHEMBL614643 HOP-62 (Non-small Cell Lung Carcinoma Cells) 2
Z81211 Z81211 CHEMBL614109 LXFL529 Cell Line 2
Z81244 Z81244 CHEMBL614123 J774 (Macrophage Cells) 2
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 2
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 2
Z81257 Z81257 CHEMBL614732 MEL-AC Cell Line 2
Z81261 Z81261 CHEMBL614127 UACC-375 2
Z81277 Z81277 CHEMBL613287 NCI-N417 2
Z81280 Z81280 CHEMBL614740 NCI-H226 (Non-small Cell Lung Carcinoma Cells) 2
Z81284 Z81284 CHEMBL614999 NCI-H647 2
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 2
Z81335 Z81335 CHEMBL612263 HCT-15 (Colon Adenocarcinoma Cells) 2
Z81341 Z81341 CHEMBL614310 Tumor Cell Lines 2
HS90B_HUMAN P08238 CHEMBL4303 Heat Shock Protein HSP 90-beta, Human 1
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 1
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 1
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 1
Z101682 Z101682 CHEMBL613915 BK Polyomavirus 1
Z101848 Z101848 CHEMBL612780 Human Herpesvirus 8 1
Z102080 Z102080 CHEMBL613316 Simplexvirus 1
Z102131 Z102131 CHEMBL613167 Vaccinia Virus Copenhagen 1
Z103196 Z103196 CHEMBL1075381 22RV1 1
Z50426 Z50426 CHEMBL612856 Plasmodium Falciparum (isolate K1 / Thailand) 1
Z50459 Z50459 CHEMBL367 Leishmania Donovani 1
Z50529 Z50529 CHEMBL613134 Cytomegalovirus 1
Z50599 Z50599 CHEMBL612672 Cowpox Virus 1
Z50624 Z50624 CHEMBL613715 Human Adenovirus Type 2 1
Z50658 Z50658 CHEMBL380 Human Immunodeficiency Virus 2 1
Z50725 Z50725 CHEMBL612348 Trypanosoma Brucei Rhodesiense 1
Z80040 Z80040 CHEMBL614527 BHK-21 (Kidney Cells) 1
Z80335 Z80335 CHEMBL614200 NHDF 1
Z80640 Z80640 CHEMBL613102 786-0 (Renal Carcinoma Cells) 1
Z80695 Z80695 CHEMBL614798 BE (Colon Adenocarcinoma Cells) 1
Z80709 Z80709 CHEMBL614359 Osteoclast-like (Bone Marrow Cells) 1
Z80823 Z80823 CHEMBL614149 E6SM (Embryonic Skin-muscle Fibroblast Cells) 1
Z81166 Z81166 CHEMBL614092 LLC Cell Line 1
Z81240 Z81240 CHEMBL614121 MAC15A (Colon Adenocarcinoma Cells) 1

Most Common Rings