UCSF

HFF (Foreskin Fibroblasts) (316 Compounds)

Swissprot:
Z80954
Stitch:
Z80954
UniProt:
Z80954
ChEMBL:
CHEMBL614071

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 0 0 0 0
Binding ≤ 1μM 0 0 0 0
Functional ≤ 10μM 316 21 12 18
ADME/T ≤ 10μM 36 2 1 1

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z50530 Z50530 CHEMBL371 Human Herpesvirus 5 115
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 52
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 48
Z50602 Z50602 CHEMBL377 Human Herpesvirus 1 38
Z50472 Z50472 CHEMBL612888 Toxoplasma Gondii 12
Z80961 Z80961 CHEMBL614828 HN5 (Squamous Cell Carcinoma) 12
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 12
Z50587 Z50587 CHEMBL372 Homo Sapiens 11
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 11
Z80244 Z80244 CHEMBL614335 MDA-MB-468 (Breast Adenocarcinoma) 10
Z80427 Z80427 CHEMBL614879 RKO (Colon Carcinoma) 10
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 10
Z50515 Z50515 CHEMBL370 Human Herpesvirus 2 8
Z80253 Z80253 CHEMBL614342 MEF (Embryonic Fibroblast Cells) 8
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 8
Z50527 Z50527 CHEMBL613132 Human Herpesvirus 3 7
Z80114 Z80114 CHEMBL614281 Daudi (Burkitts Lymphoma Cells) 6
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 6
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 6
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 5
Z80583 Z80583 CHEMBL391 Vero (Kidney Cells) 5
Z50518 Z50518 CHEMBL613124 Human Herpesvirus 4 4
Z50594 Z50594 CHEMBL375 Mus Musculus 4
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 4
Z50725 Z50725 CHEMBL612348 Trypanosoma Brucei Rhodesiense 4
Z50759 Z50759 CHEMBL612373 Dictyostelium Discoideum 4
Z80057 Z80057 CHEMBL613505 Calu-1 (Non-small Cell Lung Carcinoma Cells) 4
Z80942 Z80942 CHEMBL613888 HEL (Embryonic Lung Cells) 4
Z81024 Z81024 CHEMBL396 NCI-H460 (Non-small Cell Lung Carcinoma) 4
CP3A4_HUMAN P08684 CHEMBL340 Cytochrome P450 3A4, Human 3
Z50418 Z50418 CHEMBL612849 Trypanosoma Brucei 3
GCR_HUMAN P04150 CHEMBL2034 Glucocorticoid Receptor, Human 2
Z101794 Z101794 CHEMBL612743 Felid Herpesvirus 1 2
Z50517 Z50517 CHEMBL613123 Human Herpesvirus 5 Strain AD169 2
Z50604 Z50604 CHEMBL613495 Murid Herpesvirus 1 2
Z50606 Z50606 CHEMBL613497 Hepatitis B Virus 2
Z80005 Z80005 CHEMBL614077 3T3 (Fibroblast Cells) 2
Z80046 Z80046 CHEMBL614529 BT-474 (Breast Ductal Carcinoma Cells) 2
Z80120 Z80120 CHEMBL614285 DLD-1 (Colon Adenocarcinoma Cells) 2
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 2
Z80291 Z80291 CHEMBL614181 MRC5 (Embryonic Lung Fibroblast Cells) 2
Z80300 Z80300 CHEMBL612281 N87 (Gastric Carcinoma Cells) 2
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 2
Z80945 Z80945 CHEMBL614735 HEp-2 (Laryngeal Carcinoma Cells) 2
Z81277 Z81277 CHEMBL613287 NCI-N417 2
CP2C9_HUMAN P11712 CHEMBL3397 Cytochrome P450 2C9, Human 1
CP2CJ_HUMAN P33261 CHEMBL3622 Cytochrome P450 2C19, Human 1
CP2D6_HUMAN P10635 CHEMBL289 Cytochrome P450 2D6, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
GCR_RAT P06536 CHEMBL3368 Glucocorticoid Receptor, Rat 1
MCR_HUMAN P08235 CHEMBL1994 Mineralocorticoid Receptor, Human 1
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 1
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 1
Z103205 Z103205 CHEMBL1075390 A431 1
Z50038 Z50038 CHEMBL612328 Plasmodium Yoelii Yoelii 1
Z50076 Z50076 CHEMBL612462 Poliovirus 1
Z50426 Z50426 CHEMBL612856 Plasmodium Falciparum (isolate K1 / Thailand) 1
Z50459 Z50459 CHEMBL367 Leishmania Donovani 1
Z50473 Z50473 CHEMBL612653 Plasmodium Berghei 1
Z50529 Z50529 CHEMBL613134 Cytomegalovirus 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1
Z50600 Z50600 CHEMBL613493 Vaccinia Virus 1
Z50609 Z50609 CHEMBL613499 Simian Immunodeficiency Virus 1
Z50658 Z50658 CHEMBL380 Human Immunodeficiency Virus 2 1
Z80030 Z80030 CHEMBL614520 ANN-1 1
Z80035 Z80035 CHEMBL381 B16 (Melanoma Cells) 1
Z80040 Z80040 CHEMBL614527 BHK-21 (Kidney Cells) 1
Z80044 Z80044 CHEMBL614528 BSC-1 1
Z80110 Z80110 CHEMBL613507 CV-1 (Kidney Cells) 1
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 1
Z80169 Z80169 CHEMBL614039 Huh-7 (Hepatocellular Carcinoma) 1
Z80178 Z80178 CHEMBL614040 J774.A1 (Macrophage Cells) 1
Z80301 Z80301 CHEMBL613516 N9 1
Z80414 Z80414 CHEMBL614628 Raji (B-lymphoblastic Cells) 1
Z80418 Z80418 CHEMBL612557 RAW264.7 (Monocytic-macrophage Leukemia Cells) 1
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 1
Z80493 Z80493 CHEMBL614925 SK-OV-3 (Ovarian Carcinoma Cells) 1
Z80548 Z80548 CHEMBL614245 THP-1 (Acute Monocytic Leukemia Cells) 1
Z80823 Z80823 CHEMBL614149 E6SM (Embryonic Skin-muscle Fibroblast Cells) 1
Z80943 Z80943 CHEMBL614819 HEL 299 1
Z80951 Z80951 CHEMBL614822 NIH3T3 (Fibroblasts) 1
Z81011 Z81011 CHEMBL614840 Human Cell Lines 1
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 1
Z81244 Z81244 CHEMBL614123 J774 (Macrophage Cells) 1
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 1
Z81338 Z81338 CHEMBL614309 T-cells 1