ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (669)
Reactome (0)
Related By:
Pathway (0)
Organism (-1)
Gene (-1)
Org. Clust. (-1)
ChEMBL (113)
Rings (20)

RAW264.7 (Monocytic-macrophage Leukemia Cells) (669 Compounds)

Swissprot:: Z80418
Stitch:: Z80418
UniProt:: Z80418
ChEMBL:: CHEMBL612557

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Functional ≤ 10μM	669	107	81	20
ADME/T ≤ 10μM	41	9	9	7

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
Z50587	Z50587	CHEMBL372	Homo Sapiens	22
Z50594	Z50594	CHEMBL375	Mus Musculus	17
Z80224	Z80224	CHEMBL387	MCF7 (Breast Carcinoma Cells)	10
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	9
Z81247	Z81247	CHEMBL399	HeLa (Cervical Adenocarcinoma Cells)	9
Z80156	Z80156	CHEMBL383	HL-60 (Promyeloblast Leukemia Cells)	7
Z80548	Z80548	CHEMBL614245	THP-1 (Acute Monocytic Leukemia Cells)	6
Z80682	Z80682	CHEMBL392	A549 (Lung Carcinoma Cells)	6
Z50607	Z50607	CHEMBL378	Human Immunodeficiency Virus 1	5
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	4
Z80390	Z80390	CHEMBL390	PC-3 (Prostate Carcinoma Cells)	4
Z81135	Z81135	CHEMBL614793	L6 (Skeletal Muscle Myoblast Cells)	4
Z81252	Z81252	CHEMBL400	MDA-MB-231 (Breast Adenocarcinoma Cells)	4
Z80164	Z80164	CHEMBL614580	HT-1080 (Fibrosarcoma Cells)	3
Z81170	Z81170	CHEMBL612518	LNCaP (Prostate Carcinoma)	3
ANDR_HUMAN	P10275	CHEMBL1871	Androgen Receptor, Human	2
LOX5_HUMAN	P09917	CHEMBL215	Arachidonate 5-lipoxygenase, Human	2
PGH1_HUMAN	P23219	CHEMBL221	Cyclooxygenase-1, Human	2
Z50652	Z50652	CHEMBL613740	Influenza A Virus	2
Z80166	Z80166	CHEMBL384	HT-29 (Colon Adenocarcinoma Cells)	2
Z80186	Z80186	CHEMBL385	K562 (Erythroleukemia Cells)	2
Z80211	Z80211	CHEMBL614721	LoVo (Colon Adenocarcinoma Cells)	2
Z80244	Z80244	CHEMBL614335	MDA-MB-468 (Breast Adenocarcinoma)	2
Z80301	Z80301	CHEMBL613516	N9	2
Z80475	Z80475	CHEMBL613834	SK-BR-3 (Breast Adenocarcinoma)	2
Z81020	Z81020	CHEMBL395	HepG2 (Hepatoblastoma Cells)	2
Z81072	Z81072	CHEMBL397	Jurkat (Acute Leukemic T-cells)	2
GCR_HUMAN	P04150	CHEMBL2034	Glucocorticoid Receptor, Human	1
HDA10_HUMAN	Q969S8	CHEMBL5103	Histone Deacetylase 10, Human	1
HDA11_HUMAN	Q96DB2	CHEMBL3310	Histone Deacetylase 11, Human	1
HDAC1_HUMAN	Q13547	CHEMBL325	Histone Deacetylase 1, Human	1
HDAC2_HUMAN	Q92769	CHEMBL1937	Histone Deacetylase 2, Human	1
HDAC3_HUMAN	O15379	CHEMBL1829	Histone Deacetylase 3, Human	1
HDAC4_HUMAN	P56524	CHEMBL3524	Histone Deacetylase 4, Human	1
HDAC5_HUMAN	Q9UQL6	CHEMBL2563	Histone Deacetylase 5, Human	1
HDAC6_HUMAN	Q9UBN7	CHEMBL1865	Histone Deacetylase 6, Human	1
HDAC7_HUMAN	Q8WUI4	CHEMBL2716	Histone Deacetylase 7, Human	1
HDAC8_HUMAN	Q9BY41	CHEMBL3192	Histone Deacetylase 8, Human	1
HDAC9_HUMAN	Q9UKV0	CHEMBL4145	Histone Deacetylase 9, Human	1
LOX5_RAT	P12527	CHEMBL312	Arachidonate 5-lipoxygenase, Rat	1
NOS1_RAT	P29476	CHEMBL3048	Nitric-oxide Synthase, Brain, Rat	1
NOS2_HUMAN	P35228	CHEMBL4481	Nitric Oxide Synthase, Inducible, Human	1
NR1H2_HUMAN	P55055	CHEMBL4093	LXR-beta, Human	1
NR1H3_HUMAN	Q13133	CHEMBL2808	LXR-alpha, Human	1
NR1H4_HUMAN	Q96RI1	CHEMBL2047	Bile Acid Receptor FXR, Human	1
PGH1_BOVIN	O62664	CHEMBL2860	Cyclooxygenase-1, Bovin	1
PGH1_MOUSE	P22437	CHEMBL2649	Cyclooxygenase-1, Mouse	1
PGH1_RAT	Q63921	CHEMBL4042	Cyclooxygenase-1, Rat	1
PGH2_BOVIN	O62698	CHEMBL3331	Cyclooxygenase-2, Bovin	1
PGH2_HUMAN	P35354	CHEMBL230	Cyclooxygenase-2, Human	1
PGH2_MOUSE	Q05769	CHEMBL4321	Cyclooxygenase-2, Mouse	1
PGH2_RAT	P35355	CHEMBL2977	Cyclooxygenase-2, Rat	1
PGH2_SHEEP	P79208	CHEMBL4102	Cyclooxygenase-2, Sheep	1
Q94F81_MAIZE	Q94F81	CHEMBL4919	Histone Deacetylase HD2, Maize	1
SC6A3_RAT	P23977	CHEMBL338	Dopamine Transporter, Rat	1
THAS_HUMAN	P24557	CHEMBL1835	Thromboxane-A Synthase, Human	1
Z102015	Z102015	CHEMBL613013	Plasmodium Vivax	1
Z102178	Z102178	CHEMBL613694	Liver Microsomes	1
Z102213	Z102213	CHEMBL613416	Blood	1
Z102306	Z102306	CHEMBL613606	Aorta	1
Z102342	Z102342	CHEMBL613642	Liver	1
Z102380	Z102380	CHEMBL613680	Ileum	1
Z103192	Z103192	CHEMBL1075362	Trypanosoma Evansi	1
Z103203	Z103203	CHEMBL1075388	A375	1
Z103205	Z103205	CHEMBL1075390	A431	1
Z103348	Z103348	CHEMBL1075533	NCI-H2122	1
Z50136	Z50136	CHEMBL612608	Plasmodium Falciparum (isolate FcB1 / Columbia)	1
Z50420	Z50420	CHEMBL612851	Trypanosoma Brucei Brucei	1
Z50515	Z50515	CHEMBL370	Human Herpesvirus 2	1
Z50518	Z50518	CHEMBL613124	Human Herpesvirus 4	1
Z50530	Z50530	CHEMBL371	Human Herpesvirus 5	1
Z50600	Z50600	CHEMBL613493	Vaccinia Virus	1
Z50602	Z50602	CHEMBL377	Human Herpesvirus 1	1
Z50651	Z50651	CHEMBL613739	Vesicular Stomatitis Virus	1
Z50658	Z50658	CHEMBL380	Human Immunodeficiency Virus 2	1
Z80035	Z80035	CHEMBL381	B16 (Melanoma Cells)	1
Z80054	Z80054	CHEMBL614058	Caco-2 (Colon Adenocarcinoma Cells)	1
Z80064	Z80064	CHEMBL382	CCRF-CEM (T-cell Leukemia)	1
Z80125	Z80125	CHEMBL613508	DU-145 (Prostate Carcinoma)	1
Z80150	Z80150	CHEMBL614576	H9c2 (Cardiomyoblast Cells)	1
Z80178	Z80178	CHEMBL614040	J774.A1 (Macrophage Cells)	1
Z80322	Z80322	CHEMBL614135	NCI-H358 (Lung Carcinama Cells)	1
Z80387	Z80387	CHEMBL612556	PC-12 (Adrenal Phaeochromacytoma Cells)	1
Z80420	Z80420	CHEMBL614632	RBL-2H3 (Basophilic Leukemia Cells)	1
Z80492	Z80492	CHEMBL614924	SK-N-SH (Neuroblastoma Cells)	1
Z80493	Z80493	CHEMBL614925	SK-OV-3 (Ovarian Carcinoma Cells)	1
Z80513	Z80513	CHEMBL614939	SQ20B	1
Z80514	Z80514	CHEMBL614166	St-4 (Stomach Carcinoma Cells)	1
Z80526	Z80526	CHEMBL612544	SW480 (Colon Adenocarcinoma Cells)	1
Z80596	Z80596	CHEMBL612811	WISH (Amniotic Epithelial Cells)	1
Z80612	Z80612	CHEMBL612818	2008 (Ovarian Carcinoma Cells)	1
Z80838	Z80838	CHEMBL614489	EOL1 (Eosinophilic Cells)	1
Z80857	Z80857	CHEMBL614499	Friend Leukemia Cell Line	1
Z80874	Z80874	CHEMBL393	CEM (T-cell Leukemia)	1
Z80877	Z80877	CHEMBL612255	NCI-H1299 (Non-small Cell Lung Carcinoma)	1
Z80896	Z80896	CHEMBL614805	NCI-H69 (Small Cell Lung Carcinoma Cells)	1
Z80901	Z80901	CHEMBL614392	HaCaT (Keratinocytes)	1
Z80928	Z80928	CHEMBL394	HCT-116 (Colon Carcinoma Cells)	1
Z80954	Z80954	CHEMBL614071	HFF (Foreskin Fibroblasts)	1
Z81000	Z81000	CHEMBL614316	HT-22 (Hippocampal Cells)	1
Z81024	Z81024	CHEMBL396	NCI-H460 (Non-small Cell Lung Carcinoma)	1
Z81034	Z81034	CHEMBL614004	A2780 (Ovarian Carcinoma Cells)	1
Z81057	Z81057	CHEMBL613979	HUVEC (Umbilical Vein Endothelial Cells)	1
Z81184	Z81184	CHEMBL614096	LOX IMVI (Melanoma Cells)	1
Z81186	Z81186	CHEMBL614097	LS174T (Colon Adencocarcinoma Cells)	1
Z81245	Z81245	CHEMBL614697	MDA-MB-435 (Breast Carcinoma Cells)	1
Z81267	Z81267	CHEMBL614723	Mononuclear Cell Line	1
Z81280	Z81280	CHEMBL614740	NCI-H226 (Non-small Cell Lung Carcinoma Cells)	1
Z81281	Z81281	CHEMBL614997	NCI-H23 (Non-small Cell Lung Carcinoma Cells)	1
Z81283	Z81283	CHEMBL614387	NCI-H522 (Non-small Cell Lung Carcinoma Cells)	1
Z81331	Z81331	CHEMBL612262	SW-620 (Colon Adenocarcinoma Cells)	1
Z81335	Z81335	CHEMBL612263	HCT-15 (Colon Adenocarcinoma Cells)	1
Z81338	Z81338	CHEMBL614309	T-cells	1