UCSF

Cyclooxygenase-2, Bovin (90 Compounds)

Swissprot:
PGH2_BOVIN
Stitch:
PGH2_BOVIN
UniProt:
O62698
ChEMBL:
CHEMBL3331
PDB:
PTGS2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 90 15 11 11
Binding ≤ 1μM 56 6 6 7
Functional ≤ 10μM 2 1 1 1

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 2,153 141 77 52
PGH2_MOUSE Q05769 CHEMBL4321 Cyclooxygenase-2, Mouse 250 33 15 9
PGH2_RABIT O02768 CHEMBL1293198 Prostaglandin G/H Synthase 2, Rabit 10 2 2 1
PGH2_RAT P35355 CHEMBL2977 Cyclooxygenase-2, Rat 279 32 18 16
PGH2_SHEEP P79208 CHEMBL4102 Cyclooxygenase-2, Sheep 284 34 17 15
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PGH1_BOVIN O62664 CHEMBL2860 Cyclooxygenase-1, Bovin 100 16 12 12

Clustered By Gene (0)

Clustered By Organism (7)

Code Description Substances Purchasable Natural In Man
PGH2-1-E Cyclooxygenase-2 (cluster #1 Of 8), Eukaryotic 896 75 38 27
PGH2-2-E Cyclooxygenase-2 (cluster #2 Of 8), Eukaryotic 35 6 4 1
PGH2-3-E Cyclooxygenase-2 (cluster #3 Of 8), Eukaryotic 106 28 14 10
PGH2-4-E Cyclooxygenase-2 (cluster #4 Of 8), Eukaryotic 1,428 55 26 20
PGH2-5-E Cyclooxygenase-2 (cluster #5 Of 8), Eukaryotic 2 2 2 0
PGH2-6-E Cyclooxygenase-2 (cluster #6 Of 8), Eukaryotic 11 8 7 7
PGH2-7-E Cyclooxygenase-2 (cluster #7 Of 8), Eukaryotic 178 7 10 3
PGH2-8-E Cyclooxygenase-2 (cluster #8 Of 8), Eukaryotic 290 27 8 8
Uniprot Swissprot Chembl Description Number Shared
PGH1_BOVIN O62664 CHEMBL2860 Cyclooxygenase-1, Bovin 79
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase, Rat 16
PGH2_SHEEP P79208 CHEMBL4102 Cyclooxygenase-2, Sheep 12
Q9BEG3_BOVIN Q9BEG3 CHEMBL2980 Arachidonate 5-lipoxygenase, Bovin 12
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 11
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 8
PGH2_RAT P35355 CHEMBL2977 Cyclooxygenase-2, Rat 7
PGH1_RAT Q63921 CHEMBL4042 Cyclooxygenase-1, Rat 5
PGH1_SHEEP P05979 CHEMBL2949 Cyclooxygenase-1, Sheep 4
IL8_HUMAN P10145 CHEMBL2157 Interleukin-8, Human 3
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 3
PGH2_MOUSE Q05769 CHEMBL4321 Cyclooxygenase-2, Mouse 3
ALBU_BOVIN P02769 CHEMBL3728 Serum Albumin, Bovin 2
PGH1_MOUSE P22437 CHEMBL2649 Cyclooxygenase-1, Mouse 2
S22A6_MOUSE Q8VC69 CHEMBL5653 Solute Carrier Family 22 Member 6, Mouse 2
S22AK_MOUSE Q80UJ1 CHEMBL5269 Solute Carrier Family 22 Member 20, Mouse 2
THAS_HUMAN P24557 CHEMBL1835 Thromboxane-A Synthase, Human 2
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
B5SU02_9CNID B5SU02 CHEMBL1075028 Alpha Carbonic Anhydrase, 9cnid 1
C0IX24_9CNID C0IX24 CHEMBL1649055 Carbonic Anhydrase, 9cnid 1
CAH12_HUMAN O43570 CHEMBL3242 Carbonic Anhydrase XII, Human 1
CAH13_HUMAN Q8N1Q1 CHEMBL3912 Carbonic Anhydrase XIII, Human 1
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 1
CAH15_MOUSE Q99N23 CHEMBL5973 Carbonic Anhydrase 15, Mouse 1
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 1
CAH4_BOVIN Q95323 CHEMBL281 Carbonic Anhydrase IV, Bovin 1
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 1
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 1
CAH5B_HUMAN Q9Y2D0 CHEMBL3969 Carbonic Anhydrase VB, Human 1
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 1
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1
CAH_METTE P40881 CHEMBL3932 Carbonic Anhydrase, Mette 1
CAN_YEAST P53615 CHEMBL5931 Carbonic Anhydrase, Yeast 1
COX2_SHEEP O78750 CHEMBL1250404 Cytochrome C Oxidase Subunit 2, Sheep 1
CYNT_MYCTU O53573 CHEMBL6068 Carbonic Anhydrase, Myctu 1
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 1
LOX12_HUMAN P18054 CHEMBL3687 Arachidonate 12-lipoxygenase, Human 1
LOX15_HUMAN P16050 CHEMBL2903 Arachidonate 15-lipoxygenase, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1
PTGDS_MOUSE O09114 CHEMBL4334 Prostaglandin-H2 D-isomerase, Mouse 1
PTGES_HUMAN O14684 CHEMBL5658 Prostaglandin E Synthase, Human 1
Q5AJ71_CANAL Q5AJ71 CHEMBL5337 Carbonic Anhydrase, Canal 1
Q8HZR1_CANFA Q8HZR1 CHEMBL4133 Cyclooxygenase-1, Canine 1
Q8SPQ9_CANFA Q8SPQ9 CHEMBL4033 Cyclooxygenase-2, Canine 1
Z102213 Z102213 CHEMBL613416 Blood 1
Z50587 Z50587 CHEMBL372 Homo Sapiens 1
Z50594 Z50594 CHEMBL375 Mus Musculus 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1
Z80418 Z80418 CHEMBL612557 RAW264.7 (Monocytic-macrophage Leukemia Cells) 1
Z80548 Z80548 CHEMBL614245 THP-1 (Acute Monocytic Leukemia Cells) 1
Z81267 Z81267 CHEMBL614723 Mononuclear Cell Line 1