UCSF

Prostaglandin-H2 D-isomerase, Mouse (26 Compounds)

Swissprot:
PTGDS_MOUSE
Stitch:
PTGDS_MOUSE
UniProt:
O09114
ChEMBL:
CHEMBL4334
Reactome:
REACT_188623
PDB:
2CZT (DOCK)
2CZU (DOCK)
2E4J (DOCK)
2KTD (DOCK)
2RQ0 (DOCK)
Ptgds

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 26 6 4 5
Binding ≤ 1μM 16 4 3 4

Reactome Network (1)

Reactome ID Description Species
REACT_188623 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Mus musculus
Uniprot Swissprot Chembl Description Number Shared
PGH1_MOUSE P22437 CHEMBL2649 Cyclooxygenase-1, Mouse 1
PGH2_MOUSE Q05769 CHEMBL4321 Cyclooxygenase-2, Mouse 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PTGDS_BOVIN O02853 CHEMBL4651 Prostaglandin D2 Synthase, Bovin 1 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CNR1_RAT P20272 CHEMBL3571 Cannabinoid CB1 Receptor, Rat 4
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 2
CNR2_RAT Q9QZN9 CHEMBL2470 Cannabinoid CB2 Receptor, Rat 2
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 1
CNR2_HUMAN P34972 CHEMBL253 Cannabinoid CB2 Receptor, Human 1
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 1
IL8_HUMAN P10145 CHEMBL2157 Interleukin-8, Human 1
PGH1_BOVIN O62664 CHEMBL2860 Cyclooxygenase-1, Bovin 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
PGH1_MOUSE P22437 CHEMBL2649 Cyclooxygenase-1, Mouse 1
PGH1_RAT Q63921 CHEMBL4042 Cyclooxygenase-1, Rat 1
PGH1_SHEEP P05979 CHEMBL2949 Cyclooxygenase-1, Sheep 1
PGH2_BOVIN O62698 CHEMBL3331 Cyclooxygenase-2, Bovin 1
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 1
PGH2_MOUSE Q05769 CHEMBL4321 Cyclooxygenase-2, Mouse 1
PGH2_RAT P35355 CHEMBL2977 Cyclooxygenase-2, Rat 1
PGH2_SHEEP P79208 CHEMBL4102 Cyclooxygenase-2, Sheep 1

Most Common Rings