UCSF

G Protein-coupled Receptor 44, Human (764 Compounds)

Swissprot:
GPR44_HUMAN
Stitch:
GPR44_HUMAN
UniProt:
Q9Y5Y4
ChEMBL:
CHEMBL5071
Reactome:
REACT_19231
REACT_18425

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 764 94 5 5
Binding ≤ 1μM 630 69 4 5
Functional ≤ 10μM 325 35 2 3

Reactome Network (2)

Uniprot Swissprot Chembl Description Number Shared
IL8_HUMAN P10145 CHEMBL2157 Interleukin-8, Human 1
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 2

Prostanoid ligand receptors

Uniprot Swissprot Chembl Description Number Shared
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 76
PE2R1_HUMAN P34995 CHEMBL1811 Prostanoid EP1 Receptor, Human 1
PE2R2_HUMAN P43116 CHEMBL1881 Prostanoid EP2 Receptor, Human 3
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 2
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 1
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 1
PI2R_HUMAN P43119 CHEMBL1995 Prostanoid IP Receptor, Human 1
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 36
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GPR44_MOUSE Q9Z2J6 CHEMBL2291 G Protein-coupled Receptor 44, Mouse 10 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GPR17_HUMAN Q13304 CHEMBL1075162 Uracil Nucleotide/cysteinyl Leukotriene Receptor, Human 10 3 3 0
GPR55_HUMAN Q9Y2T6 CHEMBL1075322 G-protein Coupled Receptor 55, Human 1 1 1 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 76
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 36
GPR44_MOUSE Q9Z2J6 CHEMBL2291 G Protein-coupled Receptor 44, Mouse 10
Z81011 Z81011 CHEMBL614840 Human Cell Lines 4
PE2R2_HUMAN P43116 CHEMBL1881 Prostanoid EP2 Receptor, Human 3
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 3
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 3
Q56D28_CAVPO Q56D28 CHEMBL1075058 Chemoattractant Receptor-homologous Molecule Expressed On Th2 Cells, Guinea Pig 3
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 2
PGH1_SHEEP P05979 CHEMBL2949 Cyclooxygenase-1, Sheep 2
Q6XKD3_RAT Q6XKD3 CHEMBL1075112 G Protein-coupled Receptor 44, Rat 2
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
ALDR_RAT P07943 CHEMBL2622 Aldose Reductase, Rat 1
CCKAR_HUMAN P32238 CHEMBL1901 Cholecystokinin A Receptor, Human 1
IL8_HUMAN P10145 CHEMBL2157 Interleukin-8, Human 1
PD2R_MOUSE P70263 CHEMBL3933 Prostanoid DP Receptor, Mouse 1
PE2R1_HUMAN P34995 CHEMBL1811 Prostanoid EP1 Receptor, Human 1
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 1
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 1
PGH1_BOVIN O62664 CHEMBL2860 Cyclooxygenase-1, Bovin 1
PGH1_MOUSE P22437 CHEMBL2649 Cyclooxygenase-1, Mouse 1
PGH1_RAT Q63921 CHEMBL4042 Cyclooxygenase-1, Rat 1
PGH2_BOVIN O62698 CHEMBL3331 Cyclooxygenase-2, Bovin 1
PGH2_MOUSE Q05769 CHEMBL4321 Cyclooxygenase-2, Mouse 1
PGH2_RAT P35355 CHEMBL2977 Cyclooxygenase-2, Rat 1
PGH2_SHEEP P79208 CHEMBL4102 Cyclooxygenase-2, Sheep 1
PI2R_HUMAN P43119 CHEMBL1995 Prostanoid IP Receptor, Human 1
PTGDS_MOUSE O09114 CHEMBL4334 Prostaglandin-H2 D-isomerase, Mouse 1
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 1
Z50587 Z50587 CHEMBL372 Homo Sapiens 1