| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 213 | 6 | 3 | 4 |
| Binding ≤ 1μM | 140 | 5 | 2 | 3 |
| Functional ≤ 10μM | 22 | 4 | 1 | 2 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_18283 | G alpha (q) signalling events | Homo sapiens |
| REACT_18425 | Prostanoid ligand receptors | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| PF2R_HUMAN | P43088 | CHEMBL1987 | Prostanoid FP Receptor, Human | 40 |
| TA2R_HUMAN | P21731 | CHEMBL2069 | Thromboxane A2 Receptor, Human | 32 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| GPR44_HUMAN | Q9Y5Y4 | CHEMBL5071 | G Protein-coupled Receptor 44, Human | 1 |
| PD2R_HUMAN | Q13258 | CHEMBL4427 | Prostanoid DP Receptor, Human | 13 |
| PE2R2_HUMAN | P43116 | CHEMBL1881 | Prostanoid EP2 Receptor, Human | 60 |
| PE2R3_HUMAN | P43115 | CHEMBL3710 | Prostanoid EP3 Receptor, Human | 88 |
| PE2R4_HUMAN | P35408 | CHEMBL1836 | Prostanoid EP4 Receptor, Human | 64 |
| PF2R_HUMAN | P43088 | CHEMBL1987 | Prostanoid FP Receptor, Human | 40 |
| PI2R_HUMAN | P43119 | CHEMBL1995 | Prostanoid IP Receptor, Human | 9 |
| TA2R_HUMAN | P21731 | CHEMBL2069 | Thromboxane A2 Receptor, Human | 32 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| PE2R1_MOUSE | P35375 | CHEMBL2181 | Prostanoid EP1 Receptor, Mouse | 62 | 3 | 3 | 3 |
| PE2R1_RAT | P70597 | CHEMBL5068 | Prostanoid EP1 Receptor, Rat | 2 | 0 | 0 | 0 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| PE2R2_HUMAN | P43116 | CHEMBL1881 | Prostanoid EP2 Receptor, Human | 193 | 10 | 3 | 3 |
| PE2R3_HUMAN | P43115 | CHEMBL3710 | Prostanoid EP3 Receptor, Human | 475 | 9 | 3 | 4 |
| PE2R4_HUMAN | P35408 | CHEMBL1836 | Prostanoid EP4 Receptor, Human | 376 | 7 | 2 | 2 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| PE2R1-1-E | Prostanoid EP1 Receptor (cluster #1 Of 2), Eukaryotic | 233 | 3 | 1 | 1 |
| PE2R1-2-E | Prostanoid EP1 Receptor (cluster #2 Of 2), Eukaryotic | 42 | 6 | 5 | 6 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| PE2R3_HUMAN | P43115 | CHEMBL3710 | Prostanoid EP3 Receptor, Human | 87 |
| PE2R4_HUMAN | P35408 | CHEMBL1836 | Prostanoid EP4 Receptor, Human | 64 |
| PE2R2_HUMAN | P43116 | CHEMBL1881 | Prostanoid EP2 Receptor, Human | 60 |
| PF2R_HUMAN | P43088 | CHEMBL1987 | Prostanoid FP Receptor, Human | 39 |
| TA2R_HUMAN | P21731 | CHEMBL2069 | Thromboxane A2 Receptor, Human | 30 |
| PD2R_HUMAN | Q13258 | CHEMBL4427 | Prostanoid DP Receptor, Human | 12 |
| PI2R_HUMAN | P43119 | CHEMBL1995 | Prostanoid IP Receptor, Human | 9 |
| PE2R3_MOUSE | P30557 | CHEMBL4336 | Prostanoid EP3 Receptor, Mouse | 4 |
| PE2R1_RAT | P70597 | CHEMBL5068 | Prostanoid EP1 Receptor, Rat | 2 |
| GPR44_HUMAN | Q9Y5Y4 | CHEMBL5071 | G Protein-coupled Receptor 44, Human | 1 |
| KCNH2_HUMAN | Q12809 | CHEMBL240 | HERG, Human | 1 |
| PE2R2_RAT | Q62928 | CHEMBL4909 | Prostanoid EP2 Receptor, Rat | 1 |
| PE2R3_RAT | P34980 | CHEMBL5674 | Prostaglandin E2 Receptor EP3 Subtype, Rat | 1 |
| PE2R4_RAT | P43114 | CHEMBL4086 | Prostanoid EP4 Receptor, Rat | 1 |
| PF2R_BOVIN | P37289 | CHEMBL4820 | Prostanoid FP Receptor, Bovin | 1 |
| PF2R_MOUSE | P43117 | CHEMBL5000 | Prostaglandin F2-alpha Receptor, Mouse | 1 |
| PGH1_HUMAN | P23219 | CHEMBL221 | Cyclooxygenase-1, Human | 1 |
| S22A6_MOUSE | Q8VC69 | CHEMBL5653 | Solute Carrier Family 22 Member 6, Mouse | 1 |
| TYPH_HUMAN | P19971 | CHEMBL3106 | Thymidine Phosphorylase, Human | 1 |
| Z50589 | Z50589 | CHEMBL612670 | Felis Catus | 1 |
| Z80530 | Z80530 | CHEMBL614946 | Swiss-3T3 (Fibroblast Cells) | 1 |
