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PE2R2_HUMAN - Prostanoid EP2 Receptor, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

Prostanoid EP2 Receptor, Human (193 Compounds)

Swissprot:
PE2R2_HUMAN
Stitch:
PE2R2_HUMAN
UniProt:
P43116
ChEMBL:
CHEMBL1881
Reactome:
REACT_19327
REACT_18425
PDB:
PTGER2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 193 10 3 3
Binding ≤ 1μM 57 3 2 2
Functional ≤ 10μM 21 0 0 0

Reactome Network (2)

Reactome ID Description Species
REACT_19327 G alpha (s) signalling events Homo sapiens
REACT_18425 Prostanoid ligand receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 4
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 4
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 14
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 168
PI2R_HUMAN P43119 CHEMBL1995 Prostanoid IP Receptor, Human 11

Prostanoid ligand receptors

Uniprot Swissprot Chembl Description Number Shared
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 3
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 14
PE2R1_HUMAN P34995 CHEMBL1811 Prostanoid EP1 Receptor, Human 60
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 127
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 168
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 19
PI2R_HUMAN P43119 CHEMBL1995 Prostanoid IP Receptor, Human 11
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 22
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PE2R2_MOUSE Q62053 CHEMBL2488 Prostanoid EP2 Receptor, Mouse 114 5 3 3
PE2R2_RAT Q62928 CHEMBL4909 Prostanoid EP2 Receptor, Rat 46 2 2 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PE2R1_HUMAN P34995 CHEMBL1811 Prostanoid EP1 Receptor, Human 213 6 3 4
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 475 9 3 4
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 376 7 2 2

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PE2R2-1-E Prostanoid EP2 Receptor (cluster #1 Of 2), Eukaryotic 276 3 2 2
PE2R2-2-E Prostanoid EP2 Receptor (cluster #2 Of 2), Eukaryotic 78 15 5 5
Uniprot Swissprot Chembl Description Number Shared
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 168
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 125
PE2R1_HUMAN P34995 CHEMBL1811 Prostanoid EP1 Receptor, Human 60
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 19
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 19
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 13
PI2R_HUMAN P43119 CHEMBL1995 Prostanoid IP Receptor, Human 11
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 4
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 4
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 4
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 4
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 4
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 3
PE2R3_RAT P34980 CHEMBL5674 Prostaglandin E2 Receptor EP3 Subtype, Rat 3
PE2R2_MOUSE Q62053 CHEMBL2488 Prostanoid EP2 Receptor, Mouse 2
PE2R2_RAT Q62928 CHEMBL4909 Prostanoid EP2 Receptor, Rat 2
PE2R3_MOUSE P30557 CHEMBL4336 Prostanoid EP3 Receptor, Mouse 2
PE2R4_RAT P43114 CHEMBL4086 Prostanoid EP4 Receptor, Rat 2
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
PE2R1_MOUSE P35375 CHEMBL2181 Prostanoid EP1 Receptor, Mouse 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
S22A6_MOUSE Q8VC69 CHEMBL5653 Solute Carrier Family 22 Member 6, Mouse 1
TYPH_HUMAN P19971 CHEMBL3106 Thymidine Phosphorylase, Human 1

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