ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (354)
Reactome (2)
Related By:
Pathway (13)
Organism (1)
Gene (0)
Org. Clust. (1)
ChEMBL (42)
Rings (15)

Prostanoid DP Receptor, Human (354 Compounds)

Swissprot:: PD2R_HUMAN
Stitch:: PD2R_HUMAN
UniProt:: Q13258
ChEMBL:: CHEMBL4427
Reactome:: REACT_19327; REACT_18425
PDB:: PTGDR

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	354	12	3	4
Binding ≤ 1μM	272	4	1	1
Functional ≤ 10μM	190	1	1	1

Reactome ID	Description	Species
REACT_19327	G alpha (s) signalling events	Homo sapiens
REACT_18425	Prostanoid ligand receptors	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
ADRB1_HUMAN	P08588	CHEMBL213	Beta-1 Adrenergic Receptor, Human	1
ADRB3_HUMAN	P13945	CHEMBL246	Beta-3 Adrenergic Receptor, Human	1
DRD1_HUMAN	P21728	CHEMBL2056	Dopamine D1 Receptor, Human	1
PE2R2_HUMAN	P43116	CHEMBL1881	Prostanoid EP2 Receptor, Human	14
PE2R4_HUMAN	P35408	CHEMBL1836	Prostanoid EP4 Receptor, Human	27
PI2R_HUMAN	P43119	CHEMBL1995	Prostanoid IP Receptor, Human	16

Prostanoid ligand receptors

Uniprot	Swissprot	Chembl	Description	Number Shared
GPR44_HUMAN	Q9Y5Y4	CHEMBL5071	G Protein-coupled Receptor 44, Human	76
PE2R1_HUMAN	P34995	CHEMBL1811	Prostanoid EP1 Receptor, Human	13
PE2R2_HUMAN	P43116	CHEMBL1881	Prostanoid EP2 Receptor, Human	14
PE2R3_HUMAN	P43115	CHEMBL3710	Prostanoid EP3 Receptor, Human	24
PE2R4_HUMAN	P35408	CHEMBL1836	Prostanoid EP4 Receptor, Human	27
PF2R_HUMAN	P43088	CHEMBL1987	Prostanoid FP Receptor, Human	13
PI2R_HUMAN	P43119	CHEMBL1995	Prostanoid IP Receptor, Human	16
TA2R_HUMAN	P21731	CHEMBL2069	Thromboxane A2 Receptor, Human	219

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
PD2R_MOUSE	P70263	CHEMBL3933	Prostanoid DP Receptor, Mouse	77	0	0	0

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
PD2R-1-E	Prostanoid DP Receptor (cluster #1 Of 2), Eukaryotic	381	10	3	4
PD2R-2-E	Prostanoid DP Receptor (cluster #2 Of 2), Eukaryotic	43	5	1	1

Uniprot	Swissprot	Chembl	Description	Number Shared
TA2R_HUMAN	P21731	CHEMBL2069	Thromboxane A2 Receptor, Human	218
GPR44_HUMAN	Q9Y5Y4	CHEMBL5071	G Protein-coupled Receptor 44, Human	76
Z50587	Z50587	CHEMBL372	Homo Sapiens	34
PE2R4_HUMAN	P35408	CHEMBL1836	Prostanoid EP4 Receptor, Human	26
PE2R3_HUMAN	P43115	CHEMBL3710	Prostanoid EP3 Receptor, Human	22
PD2R_MOUSE	P70263	CHEMBL3933	Prostanoid DP Receptor, Mouse	14
PE2R2_HUMAN	P43116	CHEMBL1881	Prostanoid EP2 Receptor, Human	13
PE2R2_MOUSE	Q62053	CHEMBL2488	Prostanoid EP2 Receptor, Mouse	13
PI2R_HUMAN	P43119	CHEMBL1995	Prostanoid IP Receptor, Human	13
PE2R1_HUMAN	P34995	CHEMBL1811	Prostanoid EP1 Receptor, Human	12
PF2R_HUMAN	P43088	CHEMBL1987	Prostanoid FP Receptor, Human	12
PE2R1_MOUSE	P35375	CHEMBL2181	Prostanoid EP1 Receptor, Mouse	9
PE2R3_MOUSE	P30557	CHEMBL4336	Prostanoid EP3 Receptor, Mouse	5
PE2R4_MOUSE	P32240	CHEMBL2489	Prostanoid EP4 Receptor, Mouse	5
Q56D28_CAVPO	Q56D28	CHEMBL1075058	Chemoattractant Receptor-homologous Molecule Expressed On Th2 Cells, Guinea Pig	2
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	1
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	1
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	1
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	1
ADA2B_HUMAN	P18089	CHEMBL1942	Alpha-2b Adrenergic Receptor, Human	1
ADRB1_HUMAN	P08588	CHEMBL213	Beta-1 Adrenergic Receptor, Human	1
ADRB3_HUMAN	P13945	CHEMBL246	Beta-3 Adrenergic Receptor, Human	1
DRD1_HUMAN	P21728	CHEMBL2056	Dopamine D1 Receptor, Human	1
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	1
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	1
EGFR_HUMAN	P00533	CHEMBL203	Epidermal Growth Factor Receptor ErbB1, Human	1
GPR44_MOUSE	Q9Z2J6	CHEMBL2291	G Protein-coupled Receptor 44, Mouse	1
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	1
LOX5_HUMAN	P09917	CHEMBL215	Arachidonate 5-lipoxygenase, Human	1
NK2R_HUMAN	P21452	CHEMBL2327	Neurokinin 2 Receptor, Human	1
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	1
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	1
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	1
PE2R3_RAT	P34980	CHEMBL5674	Prostaglandin E2 Receptor EP3 Subtype, Rat	1
PF2R_BOVIN	P37289	CHEMBL4820	Prostanoid FP Receptor, Bovin	1
PF2R_MOUSE	P43117	CHEMBL5000	Prostaglandin F2-alpha Receptor, Mouse	1
PPARG_HUMAN	P37231	CHEMBL235	Peroxisome Proliferator-activated Receptor Gamma, Human	1
Q6XKD3_RAT	Q6XKD3	CHEMBL1075112	G Protein-coupled Receptor 44, Rat	1
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	1
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	1
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	1
TYPH_HUMAN	P19971	CHEMBL3106	Thymidine Phosphorylase, Human	1