UCSF

Alpha-2a Adrenergic Receptor, Human (690 Compounds)

Swissprot:
ADA2A_HUMAN
Stitch:
ADA2A_HUMAN
UniProt:
P08913
ChEMBL:
CHEMBL1867
Reactome:
REACT_19180
REACT_18339
REACT_16927
REACT_19231
REACT_19333
PDB:
1HLL (DOCK)
1HO9 (DOCK)
1HOD (DOCK)
1HOF (DOCK)
ADRA2A

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 690 104 52 54
Binding ≤ 1μM 572 80 43 46
Functional ≤ 10μM 44 9 6 6

Reactome Network (5)

Reactome ID Description Species
REACT_19180 Adrenaline signalling through Alpha-2 adrenergic receptor Homo sapiens
REACT_18339 Adrenaline,noradrenaline inhibits insulin secretion Homo sapiens
REACT_16927 Adrenoceptors Homo sapiens
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_19333 G alpha (z) signalling events Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 420
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 532

Adrenaline,noradrenaline inhibits insulin secretion

Uniprot Swissprot Chembl Description Number Shared
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 532
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 3

Adrenoceptors

Uniprot Swissprot Chembl Description Number Shared
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 187
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 165
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 148
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 420
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 532
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 18
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 10
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 8

G alpha (i) signalling events

Uniprot Swissprot Chembl Description Number Shared
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 51
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 23
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 23
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 6
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 2
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 9
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 2
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 8
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 14
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 13
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 420
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 532
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 1
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 1
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 3
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 1
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 2
CXCR3_HUMAN P49682 CHEMBL4441 C-X-C Chemokine Receptor Type 3, Human 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 82
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 57
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 39
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 11
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 7
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 44
MCHR2_HUMAN Q969V1 CHEMBL5038 Melanin-concentrating Hormone Receptor 2, Human 1
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 2
NPY1R_HUMAN P25929 CHEMBL4777 Neuropeptide Y Receptor Type 1, Human 3
NPY2R_HUMAN P49146 CHEMBL4018 Neuropeptide Y Receptor Type 2, Human 1
NPY4R_HUMAN P50391 CHEMBL4877 Neuropeptide Y Receptor Type 4, Human 1
NPY5R_HUMAN Q15761 CHEMBL4561 Neuropeptide Y Receptor Type 5, Human 19
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 4
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 7
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 9
OPRX_HUMAN P41146 CHEMBL2014 Nociceptin Receptor, Human 1
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 1

G alpha (z) signalling events

Uniprot Swissprot Chembl Description Number Shared
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 420
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 532
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 1
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 1
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 3
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 228 41 13 13
ADA2A_MOUSE Q01338 CHEMBL4075 Alpha-2a Adrenergic Receptor, Mouse 4 4 4 3
ADA2A_PIG P18871 CHEMBL2350 Alpha-2a Adrenergic Receptor, Pig 3 3 3 3
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 1,202 187 86 87

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
ADA2A-1-E Alpha-2a Adrenergic Receptor (cluster #1 Of 4), Eukaryotic 1,558 143 70 74
ADA2A-2-E Alpha-2a Adrenergic Receptor (cluster #2 Of 4), Eukaryotic 134 35 9 13
ADA2A-3-E Alpha-2a Adrenergic Receptor (cluster #3 Of 4), Eukaryotic 273 101 40 31
ADA2A-4-E Alpha-2a Adrenergic Receptor (cluster #4 Of 4), Eukaryotic 98 9 3 3
Uniprot Swissprot Chembl Description Number Shared
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 532
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 420
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 162
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 156
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 134
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 117
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 104
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 89
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 86
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 81
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 80
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 73
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 73
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 68
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 61
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 57
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 53
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 51
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 44
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 39
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 37
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 37
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 35
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 32
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 32
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 30
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 30
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 29
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 26
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 25
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 24
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 23
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 23
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 21
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 20
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 20
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 19
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 19
NPY5R_HUMAN Q15761 CHEMBL4561 Neuropeptide Y Receptor Type 5, Human 19
PNMT_HUMAN P11086 CHEMBL4617 Phenylethanolamine N-methyltransferase, Human 19
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 19
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 17
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 17
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 Receptor, Human 15
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 14
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 14
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 14
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 14
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 14
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 13
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 13
NISCH_HUMAN Q9Y2I1 CHEMBL3923 Nischarin, Human 13
PNMT_BOVIN P10938 CHEMBL2331 Phenylethanolamine N-methyltransferase, Bovin 13
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 12
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 12
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 12
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 12
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 12
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 10
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 10
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 10
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 9
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 9
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 9
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 9
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 9
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 9
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 9
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 8
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 8
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 8
ADRB2_CANFA P54833 CHEMBL2289 Beta-2 Adrenergic Receptor, Canine 7
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 Receptor, Guinea Pig 7
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 7
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 7
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 7
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 7
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 6
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 6
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 6
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 6
CAC1D_RAT P27732 CHEMBL4132 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat 6
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 6
NISCH_RAT Q4G017 CHEMBL5221 Nischarin, Rat 6
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 6
5HT4R_CAVPO O70528 CHEMBL5017 Serotonin 4 (5-HT4) Receptor, Guinea Pig 5
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 5
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 5
OPRX_RAT P35370 CHEMBL4503 Nociceptin Receptor, Rat 5
ADA2A_MOUSE Q01338 CHEMBL4075 Alpha-2a Adrenergic Receptor, Mouse 4
ADA2B_MOUSE P30545 CHEMBL2405 Alpha-2b Adrenergic Receptor, Mouse 4
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 4
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 4
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 4
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 4
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 4
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 3
5HT1D_PIG P79400 CHEMBL4105 Serotonin 1d (5-HT1d) Receptor, Pig 3
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 3
5HT3A_CAVPO O70212 CHEMBL3666 Serotonin 3a (5-HT3a) Receptor, Guinea Pig 3
5HT3B_HUMAN O95264 CHEMBL3895 Serotonin 3b (5-HT3b) Receptor, Human 3
ADA1B_MESAU P18841 CHEMBL3122 Alpha-1b Adrenergic Receptor, Mesau 3
ADA2A_PIG P18871 CHEMBL2350 Alpha-2a Adrenergic Receptor, Pig 3
ADA2B_BOVIN O77700 CHEMBL3523 Alpha-2b Adrenergic Receptor, Bovin 3
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 3
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 3
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 3
MT3_HUMAN P25713 CHEMBL1250357 Metallothionein-3, Human 3
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 3
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 3
NPY1R_HUMAN P25929 CHEMBL4777 Neuropeptide Y Receptor Type 1, Human 3
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 3
Z50512 Z50512 CHEMBL369 Cavia Porcellus 3
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 3
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 2
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 2
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 2
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 2
5HT3C_HUMAN Q8WXA8 CHEMBL4795 Serotonin 3c (5-HT3c) Receptor, Human 2
5HT3D_HUMAN Q70Z44 CHEMBL4673 Serotonin 3d (5-HT3d) Receptor, Human 2
5HT3E_HUMAN A5X5Y0 CHEMBL3812 Serotonin 3e (5-HT3e) Receptor, Human 2
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 2
5HT6R_RAT P31388 CHEMBL3372 Serotonin 6 (5-HT6) Receptor, Rat 2
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 2
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 2
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 2
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 2
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 2
AOFA_RAT P21396 CHEMBL3358 Monoamine Oxidase A, Rat 2
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 2
AOFB_RAT P19643 CHEMBL2993 Monoamine Oxidase B, Rat 2
CAC1S_RAT Q02485 CHEMBL4108 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat 2
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 2
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 2
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 2
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 2
GASR_HUMAN P32239 CHEMBL298 Cholecystokinin B Receptor, Human 2
GCR_HUMAN P04150 CHEMBL2034 Glucocorticoid Receptor, Human 2
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 2
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 2
MC4R_HUMAN P32245 CHEMBL259 Melanocortin Receptor 4, Human 2
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 2
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 2
NTR1_HUMAN P30989 CHEMBL4123 Neurotensin Receptor 1, Human 2
SC5A7_HUMAN Q9GZV3 CHEMBL4507 High-affinity Choline Transporter, Human 2
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 2
SCN1A_RAT P04774 CHEMBL4906 Sodium Channel Protein Type I Alpha Subunit, Rat 2
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 2
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 2
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 2
SCN3A_RAT P08104 CHEMBL4966 Sodium Channel Protein Type III Alpha Subunit, Rat 2
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 2
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 2
Z104283 Z104283 CHEMBL1907589 Neuronal Acetylcholine Receptor; Alpha4/beta2 2
5HT3B_MOUSE Q9JHJ5 CHEMBL3781 Serotonin 3b (5-HT3b) Receptor, Mouse 1
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 1
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 1
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 1
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 1
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 1
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 1
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 1
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 1
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 1
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 1
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 1
ADRB2_BOVIN Q28044 CHEMBL3373 Beta-2 Adrenergic Receptor, Bovin 1
ADRB2_RAT P10608 CHEMBL3754 Beta-2 Adrenergic Receptor, Rat 1
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 1
CXCR3_HUMAN P49682 CHEMBL4441 C-X-C Chemokine Receptor Type 3, Human 1
CXCR3_MOUSE O88410 CHEMBL5200 C-X-C Chemokine Receptor Type 3, Mouse 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 1
DRD4_MOUSE P51436 CHEMBL2574 Dopamine D4 Receptor, Mouse 1
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 1
DYRK2_HUMAN Q92630 CHEMBL4376 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 2, Human 1
DYRK3_HUMAN O43781 CHEMBL4575 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 3, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
HNMT_RAT Q01984 CHEMBL3241 Histamine N-methyltransferase, Rat 1
HRH2_CAVPO P47747 CHEMBL2882 Histamine H2 Receptor, Guinea Pig 1
HRH3_CAVPO Q9JI35 CHEMBL5076 Histamine H3 Receptor, Guinea Pig 1
HRH3_MOUSE P58406 CHEMBL3263 Histamine H3 Receptor, Mouse 1
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 1
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1
MCHR2_HUMAN Q969V1 CHEMBL5038 Melanin-concentrating Hormone Receptor 2, Human 1
NPY2R_HUMAN P49146 CHEMBL4018 Neuropeptide Y Receptor Type 2, Human 1
NPY4R_HUMAN P50391 CHEMBL4877 Neuropeptide Y Receptor Type 4, Human 1
NPY5R_RAT Q63634 CHEMBL2548 Neuropeptide Y Receptor Type 5, Rat 1
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 1
OPRD_PIG P79291 CHEMBL4103 Delta Opioid Receptor, Pig 1
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 1
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 1
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 1
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 1
OPRM_BOVIN P79350 CHEMBL3041 Mu Opioid Receptor, Bovin 1
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 1
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 1
OPRX_HUMAN P41146 CHEMBL2014 Nociceptin Receptor, Human 1
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 1
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 1
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 1
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 1
PI2R_HUMAN P43119 CHEMBL1995 Prostanoid IP Receptor, Human 1
PIM3_HUMAN Q86V86 CHEMBL5407 Serine/threonine-protein Kinase PIM3, Human 1
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 1
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1
S22A1_HUMAN O15245 CHEMBL5685 Solute Carrier Family 22 Member 1, Human 1
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 1
SIRT1_HUMAN Q96EB6 CHEMBL4506 NAD-dependent Deacetylase Sirtuin 1, Human 1
SIRT2_HUMAN Q8IXJ6 CHEMBL4462 NAD-dependent Deacetylase Sirtuin 2, Human 1
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 1

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