UCSF

Nischarin, Human (115 Compounds)

Swissprot:
NISCH_HUMAN
Stitch:
NISCH_HUMAN
UniProt:
Q9Y2I1
ChEMBL:
CHEMBL3923
PDB:
3P0C (DOCK)
NISCH

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 115 43 20 16
Binding ≤ 1μM 99 36 18 15

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
NISCH_RAT Q4G017 CHEMBL5221 Nischarin, Rat 36 6 1 1

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
NISCH-1-E Nischarin (cluster #1 Of 4), Eukaryotic 25 5 5 5
NISCH-2-E Nischarin (cluster #2 Of 4), Eukaryotic 113 32 12 9
NISCH-3-E Nischarin (cluster #3 Of 4), Eukaryotic 7 7 2 1
NISCH-4-E Nischarin (cluster #4 Of 4), Eukaryotic 4 3 1 1
Uniprot Swissprot Chembl Description Number Shared
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 53
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 47
ADA2B_BOVIN O77700 CHEMBL3523 Alpha-2b Adrenergic Receptor, Bovin 42
AOFA_RAT P21396 CHEMBL3358 Monoamine Oxidase A, Rat 40
AOFB_RAT P19643 CHEMBL2993 Monoamine Oxidase B, Rat 40
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 30
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 30
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 29
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 23
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 23
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 23
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 21
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 16
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 13
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 12
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 9
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 8
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 6
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 6
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 5
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 5
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 5
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 4
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 3
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 3
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 3
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 3
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 2
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 2
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 2
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 2
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 2
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 2
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 2
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 2
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 2
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 2
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 2
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 2
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 2
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 2
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 2
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 2
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 2
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 2
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 2
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 2
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 2
GASR_HUMAN P32239 CHEMBL298 Cholecystokinin B Receptor, Human 2
GCR_HUMAN P04150 CHEMBL2034 Glucocorticoid Receptor, Human 2
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 2
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 Receptor, Human 2
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 2
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 2
MC4R_HUMAN P32245 CHEMBL259 Melanocortin Receptor 4, Human 2
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 2
MT3_HUMAN P25713 CHEMBL1250357 Metallothionein-3, Human 2
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 2
NISCH_RAT Q4G017 CHEMBL5221 Nischarin, Rat 2
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 2
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 2
NPY1R_HUMAN P25929 CHEMBL4777 Neuropeptide Y Receptor Type 1, Human 2
NTR1_HUMAN P30989 CHEMBL4123 Neurotensin Receptor 1, Human 2
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 2
SC5A7_HUMAN Q9GZV3 CHEMBL4507 High-affinity Choline Transporter, Human 2
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 2
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 2
Z104283 Z104283 CHEMBL1907589 Neuronal Acetylcholine Receptor; Alpha4/beta2 2
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 1
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 1
5HT5A_MOUSE P30966 CHEMBL3597 Serotonin 5a (5-HT5a) Receptor, Mouse 1
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1
ADA1B_MESAU P18841 CHEMBL3122 Alpha-1b Adrenergic Receptor, Mesau 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1
ADA2A_MOUSE Q01338 CHEMBL4075 Alpha-2a Adrenergic Receptor, Mouse 1
ADA2A_PIG P18871 CHEMBL2350 Alpha-2a Adrenergic Receptor, Pig 1
ADA2B_MOUSE P30545 CHEMBL2405 Alpha-2b Adrenergic Receptor, Mouse 1
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 1
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 1
DYRK2_HUMAN Q92630 CHEMBL4376 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 2, Human 1
DYRK3_HUMAN O43781 CHEMBL4575 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 3, Human 1
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 1
PIM3_HUMAN Q86V86 CHEMBL5407 Serine/threonine-protein Kinase PIM3, Human 1
PNMT_BOVIN P10938 CHEMBL2331 Phenylethanolamine N-methyltransferase, Bovin 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1