ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (1,094)
Reactome (3)
Related By:
Pathway (21)
Organism (3)
Gene (0)
Org. Clust. (0)
ChEMBL (69)
Rings (8)

Cholecystokinin B Receptor, Human (1,094 Compounds)

Swissprot:: GASR_HUMAN
Stitch:: GASR_HUMAN
UniProt:: P32239
ChEMBL:: CHEMBL298
Reactome:: REACT_18283; REACT_120966; REACT_14819
PDB:: 1L4T (DOCK); CCKBR

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	1,094	24	7	7
Binding ≤ 1μM	867	21	5	3
Functional ≤ 10μM	198	2	1	1

Reactome ID	Description	Species
REACT_18283	G alpha (q) signalling events	Homo sapiens
REACT_120966	Gastrin-CREB signalling pathway via PKC and MAPK	Homo sapiens
REACT_14819	Peptide ligand-binding receptors	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	2
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	2
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	2
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic Acetylcholine Receptor M1, Human	2
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	2
ACM5_HUMAN	P08912	CHEMBL2035	Muscarinic Acetylcholine Receptor M5, Human	2
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a Adrenergic Receptor, Human	2
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	2
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	2
CCKAR_HUMAN	P32238	CHEMBL1901	Cholecystokinin A Receptor, Human	328
EDNRA_HUMAN	P25101	CHEMBL252	Endothelin Receptor ET-A, Human	2
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	2
NK1R_HUMAN	P25103	CHEMBL249	Neurokinin 1 Receptor, Human	2
NK2R_HUMAN	P21452	CHEMBL2327	Neurokinin 2 Receptor, Human	2
NTR1_HUMAN	P30989	CHEMBL4123	Neurotensin Receptor 1, Human	2

Peptide ligand-binding receptors

Uniprot	Swissprot	Chembl	Description	Number Shared
CCKAR_HUMAN	P32238	CHEMBL1901	Cholecystokinin A Receptor, Human	328
EDNRA_HUMAN	P25101	CHEMBL252	Endothelin Receptor ET-A, Human	2
MC4R_HUMAN	P32245	CHEMBL259	Melanocortin Receptor 4, Human	2
NPY1R_HUMAN	P25929	CHEMBL4777	Neuropeptide Y Receptor Type 1, Human	2
NTR1_HUMAN	P30989	CHEMBL4123	Neurotensin Receptor 1, Human	2
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	1
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	3
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	4
OPRX_HUMAN	P41146	CHEMBL2014	Nociceptin Receptor, Human	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
GASR_BOVIN	P79266	CHEMBL2720	Cholecystokinin B Receptor, Bovin	0	0	0	0
GASR_MOUSE	P56481	CHEMBL2854	Cholecystokinin B Receptor, Mouse	473	10	4	6
GASR_RAT	P30553	CHEMBL3508	Cholecystokinin B Receptor, Rat	431	12	9	8

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
CCKAR_RAT	P30551	CHEMBL2871	Cholecystokinin A Receptor, Rat	435
CCKAR_HUMAN	P32238	CHEMBL1901	Cholecystokinin A Receptor, Human	328
GASR_RAT	P30553	CHEMBL3508	Cholecystokinin B Receptor, Rat	76
GASR_MOUSE	P56481	CHEMBL2854	Cholecystokinin B Receptor, Mouse	58
CCKAR_CAVPO	Q63931	CHEMBL3501	Cholecystokinin A Receptor, Guinea Pig	39
CCKAR_MOUSE	O08786	CHEMBL2798	Cholecystokinin A Receptor, Mouse	26
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	4
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	3
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	2
5HT1B_HUMAN	P28222	CHEMBL1898	Serotonin 1b (5-HT1b) Receptor, Human	2
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	2
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	2
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	2
5HT3A_HUMAN	P46098	CHEMBL1899	Serotonin 3a (5-HT3a) Receptor, Human	2
5HT4R_HUMAN	Q13639	CHEMBL1875	Serotonin 4 (5-HT4) Receptor, Human	2
5HT7R_HUMAN	P34969	CHEMBL3155	Serotonin 7 (5-HT7) Receptor, Human	2
AA1R_HUMAN	P30542	CHEMBL226	Adenosine A1 Receptor, Human	2
AA2AR_HUMAN	P29274	CHEMBL251	Adenosine A2a Receptor, Human	2
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	2
ACES_HUMAN	P22303	CHEMBL220	Acetylcholinesterase, Human	2
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic Acetylcholine Receptor M1, Human	2
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic Acetylcholine Receptor M2, Human	2
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	2
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	2
ACM5_HUMAN	P08912	CHEMBL2035	Muscarinic Acetylcholine Receptor M5, Human	2
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a Adrenergic Receptor, Human	2
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	2
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	2
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	2
ADA2B_HUMAN	P18089	CHEMBL1942	Alpha-2b Adrenergic Receptor, Human	2
ADRB1_HUMAN	P08588	CHEMBL213	Beta-1 Adrenergic Receptor, Human	2
ADRB2_HUMAN	P07550	CHEMBL210	Beta-2 Adrenergic Receptor, Human	2
AOFA_HUMAN	P21397	CHEMBL1951	Monoamine Oxidase A, Human	2
CNR1_HUMAN	P21554	CHEMBL218	Cannabinoid CB1 Receptor, Human	2
DRD1_HUMAN	P21728	CHEMBL2056	Dopamine D1 Receptor, Human	2
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	2
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	2
EDNRA_HUMAN	P25101	CHEMBL252	Endothelin Receptor ET-A, Human	2
GCR_HUMAN	P04150	CHEMBL2034	Glucocorticoid Receptor, Human	2
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	2
HRH2_HUMAN	P25021	CHEMBL1941	Histamine H2 Receptor, Human	2
HRH3_HUMAN	Q9Y5N1	CHEMBL264	Histamine H3 Receptor, Human	2
LYN_HUMAN	P07948	CHEMBL3905	Tyrosine-protein Kinase Lyn, Human	2
MC4R_HUMAN	P32245	CHEMBL259	Melanocortin Receptor 4, Human	2
MK14_HUMAN	Q16539	CHEMBL260	MAP Kinase P38 Alpha, Human	2
MT3_HUMAN	P25713	CHEMBL1250357	Metallothionein-3, Human	2
MTR1A_HUMAN	P48039	CHEMBL1945	Melatonin Receptor 1A, Human	2
NISCH_HUMAN	Q9Y2I1	CHEMBL3923	Nischarin, Human	2
NK1R_HUMAN	P25103	CHEMBL249	Neurokinin 1 Receptor, Human	2
NK2R_HUMAN	P21452	CHEMBL2327	Neurokinin 2 Receptor, Human	2
NPY1R_HUMAN	P25929	CHEMBL4777	Neuropeptide Y Receptor Type 1, Human	2
NTR1_HUMAN	P30989	CHEMBL4123	Neurotensin Receptor 1, Human	2
OPRD_RAT	P33533	CHEMBL269	Delta Opioid Receptor, Rat	2
OPRM_RAT	P33535	CHEMBL270	Mu Opioid Receptor, Rat	2
SC5A7_HUMAN	Q9GZV3	CHEMBL4507	High-affinity Choline Transporter, Human	2
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	2
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	2
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	2
Z104283	Z104283	CHEMBL1907589	Neuronal Acetylcholine Receptor; Alpha4/beta2	2
KCND3_HUMAN	Q9UK17	CHEMBL1964	Voltage-gated Potassium Channel Subunit Kv4.3, Human	1
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	1
KCNQ1_CAVPO	O70344	CHEMBL5135	Voltage-gated Potassium Channel Subunit Kv7.1, Guinea Pig	1
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	1
OPRK_CAVPO	P41144	CHEMBL3952	Kappa Opioid Receptor, Guinea Pig	1
OPRK_RAT	P34975	CHEMBL3614	Kappa Opioid Receptor, Rat	1
OPRM_CAVPO	P97266	CHEMBL4354	Mu Opioid Receptor, Guinea Pig	1
OPRX_HUMAN	P41146	CHEMBL2014	Nociceptin Receptor, Human	1
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	1
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	1