ZINC 12

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Names
Compounds (1,915)
Reactome (2)
Related By:
Pathway (19)
Organism (3)
Gene (0)
Org. Clust. (2)
ChEMBL (140)
Rings (50)

Delta Opioid Receptor, Rat (1,915 Compounds)

Swissprot:: OPRD_RAT
Stitch:: OPRD_RAT
UniProt:: P33533
ChEMBL:: CHEMBL269
Reactome:: REACT_233455; REACT_250028
PDB:: Oprd1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	1,915	66	39	51
Binding ≤ 1μM	1,613	56	31	46
Functional ≤ 10μM	34	1	0	0

Reactome ID	Description	Species
REACT_233455	G alpha (i) signalling events	Rattus norvegicus
REACT_250028	Peptide ligand-binding receptors	Rattus norvegicus

Uniprot	Swissprot	Chembl	Description	Number Shared
5HT1B_RAT	P28564	CHEMBL3459	Serotonin 1b (5-HT1b) Receptor, Rat	3
5HT1D_RAT	P28565	CHEMBL5450	Serotonin 1d (5-HT1d) Receptor, Rat	3
5HT5A_RAT	P35364	CHEMBL4655	Serotonin 5a (5-HT5a) Receptor, Rat	1
ACM2_RAT	P10980	CHEMBL309	Muscarinic Acetylcholine Receptor M2, Rat	3
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	4
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	4
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	4
ADCY2_RAT	P26769	CHEMBL2958	Adenylate Cyclase Type II, Rat	1
D4A3N4_RAT	D4A3N4	CHEMBL2679	Brain Adenylate Cyclase 1, Rat	1
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	10
DRD3_RAT	P19020	CHEMBL3138	Dopamine D3 Receptor, Rat	3
DRD4_RAT	P30729	CHEMBL3361	Dopamine D4 Receptor, Rat	3
OPRK_RAT	P34975	CHEMBL3614	Kappa Opioid Receptor, Rat	513
OPRM_RAT	P33535	CHEMBL270	Mu Opioid Receptor, Rat	1757
OPRX_RAT	P35370	CHEMBL4503	Nociceptin Receptor, Rat	14
Q8CFM9_RAT	Q8CFM9	CHEMBL3940	Adenylate Cyclase Type VII, Rat	1

Peptide ligand-binding receptors

Uniprot	Swissprot	Chembl	Description	Number Shared
OPRK_RAT	P34975	CHEMBL3614	Kappa Opioid Receptor, Rat	513
OPRM_RAT	P33535	CHEMBL270	Mu Opioid Receptor, Rat	1757
OPRX_RAT	P35370	CHEMBL4503	Nociceptin Receptor, Rat	14

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	2,756	80	45	46
OPRD_MOUSE	P32300	CHEMBL3222	Delta Opioid Receptor, Mouse	359	21	12	16
OPRD_PIG	P79291	CHEMBL4103	Delta Opioid Receptor, Pig	187	4	4	1

Clustered By Gene (0)

Clustered By Organism (2)

Code	Description	Substances	Purchasable	Natural	In Man
OPRD-1-E	Delta Opioid Receptor (cluster #1 Of 3), Eukaryotic	4,915	142	74	93
OPRD-2-E	Delta Opioid Receptor (cluster #2 Of 3), Eukaryotic	1	0	1	1
OPRD-3-E	Delta Opioid Receptor (cluster #3 Of 3), Eukaryotic	4	2	0	0

Uniprot	Swissprot	Chembl	Description	Number Shared
OPRM_RAT	P33535	CHEMBL270	Mu Opioid Receptor, Rat	1757
OPRK_RAT	P34975	CHEMBL3614	Kappa Opioid Receptor, Rat	513
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	353
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	291
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	158
OPRK_CAVPO	P41144	CHEMBL3952	Kappa Opioid Receptor, Guinea Pig	139
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	134
OPRM_MOUSE	P42866	CHEMBL2858	Mu Opioid Receptor, Mouse	107
OPRD_MOUSE	P32300	CHEMBL3222	Delta Opioid Receptor, Mouse	85
OPRD_PIG	P79291	CHEMBL4103	Delta Opioid Receptor, Pig	84
OPRM_CAVPO	P97266	CHEMBL4354	Mu Opioid Receptor, Guinea Pig	54
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	37
Z50512	Z50512	CHEMBL369	Cavia Porcellus	32
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	26
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	26
Z104304	Z104304	CHEMBL1907610	Adrenergic Receptor Alpha-1	26
CCKAR_RAT	P30551	CHEMBL2871	Cholecystokinin A Receptor, Rat	25
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	24
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	19
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	19
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	17
Z100491	Z100491	CHEMBL613288	Sigma 2 Receptor	16
OPRK_MOUSE	P33534	CHEMBL4329	Kappa Opioid Receptor, Mouse	15
OPRX_RAT	P35370	CHEMBL4503	Nociceptin Receptor, Rat	14
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	10
SGMR1_MOUSE	O55242	CHEMBL3465	Sigma Opioid Receptor, Mouse	9
OPRM_BOVIN	P79350	CHEMBL3041	Mu Opioid Receptor, Bovin	8
OPRX_HUMAN	P41146	CHEMBL2014	Nociceptin Receptor, Human	8
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	5
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	4
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	4
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	4
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	4
NMD3B_RAT	Q8VHN2	CHEMBL282	Glutamate [NMDA] Receptor Subunit 3B, Rat	4
NMDE2_RAT	Q00960	CHEMBL311	Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat	4
NMDE3_RAT	Q00961	CHEMBL401	Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat	4
NMDE4_RAT	Q62645	CHEMBL303	Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat	4
Z104303	Z104303	CHEMBL1907609	Muscarinic Acetylcholine Receptor	4
5HT1A_RAT	P19327	CHEMBL273	Serotonin 1a (5-HT1a) Receptor, Rat	3
5HT1B_RAT	P28564	CHEMBL3459	Serotonin 1b (5-HT1b) Receptor, Rat	3
5HT1D_RAT	P28565	CHEMBL5450	Serotonin 1d (5-HT1d) Receptor, Rat	3
5HT1F_RAT	P30940	CHEMBL4646	Serotonin 1f (5-HT1f) Receptor, Rat	3
5HT2A_RAT	P14842	CHEMBL322	Serotonin 2a (5-HT2a) Receptor, Rat	3
5HT2B_RAT	P30994	CHEMBL323	Serotonin 2b (5-HT2b) Receptor, Rat	3
5HT2C_RAT	P08909	CHEMBL324	Serotonin 2c (5-HT2c) Receptor, Rat	3
ACM1_RAT	P08482	CHEMBL276	Muscarinic Acetylcholine Receptor M1, Rat	3
ACM2_RAT	P10980	CHEMBL309	Muscarinic Acetylcholine Receptor M2, Rat	3
DRD1_BOVIN	Q95136	CHEMBL2967	Dopamine D1 Receptor, Bovin	3
DRD1_HUMAN	P21728	CHEMBL2056	Dopamine D1 Receptor, Human	3
DRD1_RAT	P18901	CHEMBL265	Dopamine D1 Receptor, Rat	3
DRD2_BOVIN	P20288	CHEMBL3998	Dopamine D2 Receptor, Bovin	3
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	3
DRD3_RAT	P19020	CHEMBL3138	Dopamine D3 Receptor, Rat	3
DRD4_RAT	P30729	CHEMBL3361	Dopamine D4 Receptor, Rat	3
DRD5_HUMAN	P21918	CHEMBL1850	Dopamine D5 Receptor, Human	3
DRD5_RAT	P25115	CHEMBL2281	Dopamine D5 Receptor, Rat	3
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	3
5HT7R_RAT	P32305	CHEMBL3223	Serotonin 7 (5-HT7) Receptor, Rat	2
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a Adrenergic Receptor, Human	2
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	2
ADA1B_RAT	P15823	CHEMBL315	Alpha-1b Adrenergic Receptor, Rat	2
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	2
ADRB1_RAT	P18090	CHEMBL3252	Beta-1 Adrenergic Receptor, Rat	2
EBP_HUMAN	Q15125	CHEMBL4931	3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human	2
ERG2_YEAST	P32352	CHEMBL3224	C-8 Sterol Isomerase, Yeast	2
GASR_HUMAN	P32239	CHEMBL298	Cholecystokinin B Receptor, Human	2
HRH1_RAT	P31390	CHEMBL4701	Histamine H1 Receptor, Rat	2
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	2
NMD3A_HUMAN	Q8TCU5	CHEMBL4787	Glutamate [NMDA] Receptor Subunit 3A, Human	2
NMD3B_HUMAN	O60391	CHEMBL2913	Glutamate [NMDA] Receptor Subunit 3B, Human	2
NMDE1_HUMAN	Q12879	CHEMBL1972	Glutamate [NMDA] Receptor Subunit Epsilon 1, Human	2
NMDE2_HUMAN	Q13224	CHEMBL1904	Glutamate [NMDA] Receptor Subunit Epsilon 2, Human	2
NMDE3_HUMAN	Q14957	CHEMBL4109	Glutamate [NMDA] Receptor Subunit Epsilon 3, Human	2
NMDE4_HUMAN	O15399	CHEMBL2591	Glutamate [NMDA] Receptor Subunit Epsilon 4, Human	2
NMDZ1_HUMAN	Q05586	CHEMBL2015	Glutamate (NMDA) Receptor Subunit Zeta 1, Human	2
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	2
SCN1A_HUMAN	P35498	CHEMBL1845	Sodium Channel Protein Type I Alpha Subunit, Human	2
SCN2A_HUMAN	Q99250	CHEMBL4187	Sodium Channel Protein Type II Alpha Subunit, Human	2
SCN3A_HUMAN	Q9NY46	CHEMBL5163	Sodium Channel Protein Type III Alpha Subunit, Human	2
SCN8A_HUMAN	Q9UQD0	CHEMBL5202	Sodium Channel Protein Type VIII Alpha Subunit, Human	2
Z100254	Z100254	CHEMBL613295	Monoclonal Antibody (mAb) 3E7	2
5HT1E_HUMAN	P28566	CHEMBL2182	Serotonin 1e (5-HT1e) Receptor, Human	1
5HT2A_BOVIN	Q75Z89	CHEMBL3446	Serotonin 2a (5-HT2a) Receptor, Bovin	1
5HT2A_MOUSE	P35363	CHEMBL5377	Serotonin 2a (5-HT2a) Receptor, Mouse	1
5HT2A_PIG	P50129	CHEMBL2490	Serotonin 2a (5-HT2a) Receptor, Pig	1
5HT2B_MOUSE	Q02152	CHEMBL2583	Serotonin 2b (5-HT2b) Receptor, Mouse	1
5HT2C_MOUSE	P34968	CHEMBL3006	Serotonin 2c (5-HT2c) Receptor, Mouse	1
5HT4R_RAT	Q62758	CHEMBL4317	Serotonin 4 (5-HT4) Receptor, Rat	1
5HT5A_RAT	P35364	CHEMBL4655	Serotonin 5a (5-HT5a) Receptor, Rat	1
5HT5B_RAT	P35365	CHEMBL2619	Serotonin 5b (5-HT5b) Receptor, Rat	1
5HT6R_HUMAN	P50406	CHEMBL3371	Serotonin 6 (5-HT6) Receptor, Human	1
5HT6R_RAT	P31388	CHEMBL3372	Serotonin 6 (5-HT6) Receptor, Rat	1
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	1
ACES_ELEEL	O42275	CHEMBL4078	Acetylcholinesterase, Eleel	1
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic Acetylcholine Receptor M1, Human	1
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic Acetylcholine Receptor M2, Human	1
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	1
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	1
ACM5_HUMAN	P08912	CHEMBL2035	Muscarinic Acetylcholine Receptor M5, Human	1
ADA1A_BOVIN	P18130	CHEMBL4892	Alpha-1a Adrenergic Receptor, Bovin	1
ADA1A_RAT	P43140	CHEMBL319	Alpha-1a Adrenergic Receptor, Rat	1
ADA1D_RAT	P23944	CHEMBL326	Alpha-1d Adrenergic Receptor, Rat	1
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	1
ADCY2_RAT	P26769	CHEMBL2958	Adenylate Cyclase Type II, Rat	1
ADCY3_RAT	P21932	CHEMBL4864	Adenylate Cyclase Type III, Rat	1
ADCY4_RAT	P26770	CHEMBL2879	Adenylate Cyclase Type IV, Rat	1
ADCY5_RAT	Q04400	CHEMBL2880	Adenylate Cyclase Type V, Rat	1
ADCY6_RAT	Q03343	CHEMBL2975	Adenylate Cyclase Type VI, Rat	1
ADCY8_RAT	P40146	CHEMBL3082	Adenylate Cyclase Type VIII, Rat	1
ADRB2_CANFA	P54833	CHEMBL2289	Beta-2 Adrenergic Receptor, Canine	1
ADRB3_RAT	P26255	CHEMBL4031	Beta-3 Adrenergic Receptor, Rat	1
AOFA_HUMAN	P21397	CHEMBL1951	Monoamine Oxidase A, Human	1
AOFB_HUMAN	P27338	CHEMBL2039	Monoamine Oxidase B, Human	1
AP2S1_RAT	P62744	CHEMBL1697667	AP-2 Complex Subunit Sigma, Rat	1
CCKAR_HUMAN	P32238	CHEMBL1901	Cholecystokinin A Receptor, Human	1
CCR5_MOUSE	P51682	CHEMBL3676	C-C Chemokine Receptor Type 5, Mouse	1
D4A3N4_RAT	D4A3N4	CHEMBL2679	Brain Adenylate Cyclase 1, Rat	1
DRD1_MOUSE	Q61616	CHEMBL3071	Dopamine D1 Receptor, Mouse	1
DRD1_PIG	P50130	CHEMBL5067	Dopamine D1 Receptor, Pig	1
DRD2_CHLAE	P52702	CHEMBL5456	Dopamine D2 Receptor, Chlae	1
EBP_CAVPO	Q60490	CHEMBL5525	3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Guinea Pig	1
GASR_MOUSE	P56481	CHEMBL2854	Cholecystokinin B Receptor, Mouse	1
GASR_RAT	P30553	CHEMBL3508	Cholecystokinin B Receptor, Rat	1
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	1
MDR1_HUMAN	P08183	CHEMBL4302	P-glycoprotein 1, Human	1
MTR1A_HUMAN	P48039	CHEMBL1945	Melatonin Receptor 1A, Human	1
MTR1B_HUMAN	P49286	CHEMBL1946	Melatonin Receptor 1B, Human	1
NK1R_RAT	P14600	CHEMBL4027	Neurokinin 1 Receptor, Rat	1
OPRM_MACMU	Q9MYW9	CHEMBL5799	Mu-type Opioid Receptor, Macmu	1
PDYN_HUMAN	P01213	CHEMBL2227	Proenkephalin B, Human	1
Q4U254_9ENTO	Q4U254	CHEMBL2857	Human Rhinovirus A Protease, 9ento	1
Q63380_RAT	Q63380	CHEMBL6184	Transporter, Rat	1
Q72874_9HIV1	Q72874	CHEMBL243	Human Immunodeficiency Virus Type 1 Protease, 9hiv1	1
Q8CFM9_RAT	Q8CFM9	CHEMBL3940	Adenylate Cyclase Type VII, Rat	1
Q9WTR4_RAT	Q9WTR4	CHEMBL304	Norepinephrine Transporter, Rat	1
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	1
SC6A3_RAT	P23977	CHEMBL338	Dopamine Transporter, Rat	1
SC6A4_RAT	P31652	CHEMBL313	Serotonin Transporter, Rat	1
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	1
Z50594	Z50594	CHEMBL375	Mus Musculus	1