UCSF

Delta Opioid Receptor, Rat (1,915 Compounds)

Swissprot:
OPRD_RAT
Stitch:
OPRD_RAT
UniProt:
P33533
ChEMBL:
CHEMBL269
Reactome:
REACT_233455
REACT_250028
PDB:
Oprd1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1,915 66 39 51
Binding ≤ 1μM 1,613 56 31 46
Functional ≤ 10μM 34 1 0 0

Reactome Network (2)

Reactome ID Description Species
REACT_233455 G alpha (i) signalling events Rattus norvegicus
REACT_250028 Peptide ligand-binding receptors Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 3
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 3
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 3
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 4
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 4
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 4
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
D4A3N4_RAT D4A3N4 CHEMBL2679 Brain Adenylate Cyclase 1, Rat 1
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 10
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 3
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 3
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 513
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 1757
OPRX_RAT P35370 CHEMBL4503 Nociceptin Receptor, Rat 14
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1

Peptide ligand-binding receptors

Uniprot Swissprot Chembl Description Number Shared
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 513
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 1757
OPRX_RAT P35370 CHEMBL4503 Nociceptin Receptor, Rat 14
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 2,756 80 45 46
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 359 21 12 16
OPRD_PIG P79291 CHEMBL4103 Delta Opioid Receptor, Pig 187 4 4 1

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
OPRD-1-E Delta Opioid Receptor (cluster #1 Of 3), Eukaryotic 4,915 142 74 93
OPRD-2-E Delta Opioid Receptor (cluster #2 Of 3), Eukaryotic 1 0 1 1
OPRD-3-E Delta Opioid Receptor (cluster #3 Of 3), Eukaryotic 4 2 0 0
Uniprot Swissprot Chembl Description Number Shared
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 1757
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 513
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 353
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 291
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 158
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 139
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 134
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 107
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 85
OPRD_PIG P79291 CHEMBL4103 Delta Opioid Receptor, Pig 84
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 54
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 37
Z50512 Z50512 CHEMBL369 Cavia Porcellus 32
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 26
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 26
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 26
CCKAR_RAT P30551 CHEMBL2871 Cholecystokinin A Receptor, Rat 25
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 24
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 19
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 19
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 17
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 16
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 15
OPRX_RAT P35370 CHEMBL4503 Nociceptin Receptor, Rat 14
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 10
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 9
OPRM_BOVIN P79350 CHEMBL3041 Mu Opioid Receptor, Bovin 8
OPRX_HUMAN P41146 CHEMBL2014 Nociceptin Receptor, Human 8
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 5
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 4
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 4
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 4
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 4
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 4
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 4
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 4
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 4
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 4
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 3
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 3
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 3
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 3
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 3
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 3
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 3
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 3
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 3
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 3
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 3
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 3
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 3
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 3
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 3
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 3
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 3
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 3
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 3
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 2
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 2
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 2
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 2
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 2
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 2
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 2
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 2
GASR_HUMAN P32239 CHEMBL298 Cholecystokinin B Receptor, Human 2
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 2
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 2
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 2
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 2
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 2
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 2
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 2
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 2
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 2
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 2
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 2
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 2
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 2
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 2
Z100254 Z100254 CHEMBL613295 Monoclonal Antibody (mAb) 3E7 2
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 1
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 1
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 1
5HT2A_PIG P50129 CHEMBL2490 Serotonin 2a (5-HT2a) Receptor, Pig 1
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 1
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 1
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 1
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 1
5HT5B_RAT P35365 CHEMBL2619 Serotonin 5b (5-HT5b) Receptor, Rat 1
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1
5HT6R_RAT P31388 CHEMBL3372 Serotonin 6 (5-HT6) Receptor, Rat 1
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 1
ACES_ELEEL O42275 CHEMBL4078 Acetylcholinesterase, Eleel 1
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 1
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 1
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 1
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 1
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 1
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 1
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 1
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 1
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 1
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 1
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 1
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 1
ADRB2_CANFA P54833 CHEMBL2289 Beta-2 Adrenergic Receptor, Canine 1
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 1
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 1
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 1
AP2S1_RAT P62744 CHEMBL1697667 AP-2 Complex Subunit Sigma, Rat 1
CCKAR_HUMAN P32238 CHEMBL1901 Cholecystokinin A Receptor, Human 1
CCR5_MOUSE P51682 CHEMBL3676 C-C Chemokine Receptor Type 5, Mouse 1
D4A3N4_RAT D4A3N4 CHEMBL2679 Brain Adenylate Cyclase 1, Rat 1
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 1
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 1
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 1
EBP_CAVPO Q60490 CHEMBL5525 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Guinea Pig 1
GASR_MOUSE P56481 CHEMBL2854 Cholecystokinin B Receptor, Mouse 1
GASR_RAT P30553 CHEMBL3508 Cholecystokinin B Receptor, Rat 1
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 1
MTR1B_HUMAN P49286 CHEMBL1946 Melatonin Receptor 1B, Human 1
NK1R_RAT P14600 CHEMBL4027 Neurokinin 1 Receptor, Rat 1
OPRM_MACMU Q9MYW9 CHEMBL5799 Mu-type Opioid Receptor, Macmu 1
PDYN_HUMAN P01213 CHEMBL2227 Proenkephalin B, Human 1
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 1
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 1
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 1
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 1
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 1
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 1
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 1
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 1
Z50594 Z50594 CHEMBL375 Mus Musculus 1