ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (52)
Reactome (1)
Related By:
Pathway (1)
Organism (1)
Gene (0)
Org. Clust. (0)
ChEMBL (110)
Rings (5)

3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human (52 Compounds)

Swissprot:: EBP_HUMAN
Stitch:: EBP_HUMAN
UniProt:: Q15125
ChEMBL:: CHEMBL4931
Reactome:: REACT_9405
PDB:: EBP

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	52	26	22	21
Binding ≤ 1μM	44	23	21	19

Reactome ID	Description	Species
REACT_9405	Cholesterol biosynthesis	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
FDFT_HUMAN	P37268	CHEMBL3338	Squalene Synthetase, Human	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
EBP_CAVPO	Q60490	CHEMBL5525	3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Guinea Pig	116	9	1	1

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	49
ERG2_YEAST	P32352	CHEMBL3224	C-8 Sterol Isomerase, Yeast	47
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	7
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	6
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	5
MDR1_HUMAN	P08183	CHEMBL4302	P-glycoprotein 1, Human	4
5HT1A_RAT	P19327	CHEMBL273	Serotonin 1a (5-HT1a) Receptor, Rat	3
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	3
EBP_CAVPO	Q60490	CHEMBL5525	3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Guinea Pig	3
Z100491	Z100491	CHEMBL613288	Sigma 2 Receptor	3
5HT2A_RAT	P14842	CHEMBL322	Serotonin 2a (5-HT2a) Receptor, Rat	2
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	2
5HT2B_RAT	P30994	CHEMBL323	Serotonin 2b (5-HT2b) Receptor, Rat	2
5HT2C_RAT	P08909	CHEMBL324	Serotonin 2c (5-HT2c) Receptor, Rat	2
ACM1_RAT	P08482	CHEMBL276	Muscarinic Acetylcholine Receptor M1, Rat	2
ACM2_RAT	P10980	CHEMBL309	Muscarinic Acetylcholine Receptor M2, Rat	2
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a Adrenergic Receptor, Human	2
DRD1_RAT	P18901	CHEMBL265	Dopamine D1 Receptor, Rat	2
DRD2_BOVIN	P20288	CHEMBL3998	Dopamine D2 Receptor, Bovin	2
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	2
DRD3_RAT	P19020	CHEMBL3138	Dopamine D3 Receptor, Rat	2
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	2
DRD4_RAT	P30729	CHEMBL3361	Dopamine D4 Receptor, Rat	2
DRD5_RAT	P25115	CHEMBL2281	Dopamine D5 Receptor, Rat	2
ERG7_RAT	P48450	CHEMBL3262	Lanosterol Synthase, Rat	2
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	2
ESR1_RAT	P06211	CHEMBL2724	Estrogen Receptor Alpha, Rat	2
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	2
ESR2_RAT	Q62986	CHEMBL3021	Estrogen Receptor Beta, Rat	2
OPRD_RAT	P33533	CHEMBL269	Delta Opioid Receptor, Rat	2
OPRK_RAT	P34975	CHEMBL3614	Kappa Opioid Receptor, Rat	2
OPRM_RAT	P33535	CHEMBL270	Mu Opioid Receptor, Rat	2
SCN1A_HUMAN	P35498	CHEMBL1845	Sodium Channel Protein Type I Alpha Subunit, Human	2
SCN2A_HUMAN	Q99250	CHEMBL4187	Sodium Channel Protein Type II Alpha Subunit, Human	2
SCN3A_HUMAN	Q9NY46	CHEMBL5163	Sodium Channel Protein Type III Alpha Subunit, Human	2
SCN8A_HUMAN	Q9UQD0	CHEMBL5202	Sodium Channel Protein Type VIII Alpha Subunit, Human	2
Z104304	Z104304	CHEMBL1907610	Adrenergic Receptor Alpha-1	2
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	1
5HT1B_RAT	P28564	CHEMBL3459	Serotonin 1b (5-HT1b) Receptor, Rat	1
5HT1D_RAT	P28565	CHEMBL5450	Serotonin 1d (5-HT1d) Receptor, Rat	1
5HT1E_HUMAN	P28566	CHEMBL2182	Serotonin 1e (5-HT1e) Receptor, Human	1
5HT1F_RAT	P30940	CHEMBL4646	Serotonin 1f (5-HT1f) Receptor, Rat	1
5HT2A_BOVIN	Q75Z89	CHEMBL3446	Serotonin 2a (5-HT2a) Receptor, Bovin	1
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	1
5HT2A_MOUSE	P35363	CHEMBL5377	Serotonin 2a (5-HT2a) Receptor, Mouse	1
5HT2A_PIG	P50129	CHEMBL2490	Serotonin 2a (5-HT2a) Receptor, Pig	1
5HT2B_MOUSE	Q02152	CHEMBL2583	Serotonin 2b (5-HT2b) Receptor, Mouse	1
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	1
5HT2C_MOUSE	P34968	CHEMBL3006	Serotonin 2c (5-HT2c) Receptor, Mouse	1
5HT6R_HUMAN	P50406	CHEMBL3371	Serotonin 6 (5-HT6) Receptor, Human	1
5HT7R_RAT	P32305	CHEMBL3223	Serotonin 7 (5-HT7) Receptor, Rat	1
A3EZI9_9HEPC	A3EZI9	CHEMBL4893	Hepatitis C Virus NS3 Protease/helicase, 9hepc	1
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic Acetylcholine Receptor M1, Human	1
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic Acetylcholine Receptor M2, Human	1
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	1
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	1
ACM5_HUMAN	P08912	CHEMBL2035	Muscarinic Acetylcholine Receptor M5, Human	1
ADA1A_BOVIN	P18130	CHEMBL4892	Alpha-1a Adrenergic Receptor, Bovin	1
ADA1A_RAT	P43140	CHEMBL319	Alpha-1a Adrenergic Receptor, Rat	1
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	1
ADA1B_RAT	P15823	CHEMBL315	Alpha-1b Adrenergic Receptor, Rat	1
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	1
ADA1D_RAT	P23944	CHEMBL326	Alpha-1d Adrenergic Receptor, Rat	1
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	1
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	1
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	1
AP2S1_RAT	P62744	CHEMBL1697667	AP-2 Complex Subunit Sigma, Rat	1
BGLR_RAT	P06760	CHEMBL4814	Beta-glucuronidase, Rat	1
CALM_HUMAN	P62158	CHEMBL6093	Calmodulin, Human	1
CYSP_TRYCR	P25779	CHEMBL3563	Cruzipain, Trycr	1
DRD1_BOVIN	Q95136	CHEMBL2967	Dopamine D1 Receptor, Bovin	1
DRD1_HUMAN	P21728	CHEMBL2056	Dopamine D1 Receptor, Human	1
DRD1_PIG	P50130	CHEMBL5067	Dopamine D1 Receptor, Pig	1
DRD2_CHLAE	P52702	CHEMBL5456	Dopamine D2 Receptor, Chlae	1
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	1
DRD5_HUMAN	P21918	CHEMBL1850	Dopamine D5 Receptor, Human	1
FDFT_HUMAN	P37268	CHEMBL3338	Squalene Synthetase, Human	1
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	1
HRH1_RAT	P31390	CHEMBL4701	Histamine H1 Receptor, Rat	1
LEF_BACAN	P15917	CHEMBL4372	Anthrax Lethal Factor, Bacan	1
LYSC1_RAT	P00697	CHEMBL2297	Lysozyme C, Rat	1
NMD3A_HUMAN	Q8TCU5	CHEMBL4787	Glutamate [NMDA] Receptor Subunit 3A, Human	1
NMD3B_HUMAN	O60391	CHEMBL2913	Glutamate [NMDA] Receptor Subunit 3B, Human	1
NMDE1_HUMAN	Q12879	CHEMBL1972	Glutamate [NMDA] Receptor Subunit Epsilon 1, Human	1
NMDE2_HUMAN	Q13224	CHEMBL1904	Glutamate [NMDA] Receptor Subunit Epsilon 2, Human	1
NMDE2_RAT	Q00960	CHEMBL311	Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat	1
NMDE3_HUMAN	Q14957	CHEMBL4109	Glutamate [NMDA] Receptor Subunit Epsilon 3, Human	1
NMDE4_HUMAN	O15399	CHEMBL2591	Glutamate [NMDA] Receptor Subunit Epsilon 4, Human	1
NMDZ1_HUMAN	Q05586	CHEMBL2015	Glutamate (NMDA) Receptor Subunit Zeta 1, Human	1
NMDZ1_RAT	P35439	CHEMBL330	Glutamate (NMDA) Receptor Subunit Zeta 1, Rat	1
O77823_PIG	O77823	CHEMBL3333	Phosphodiesterase 4A, Pig	1
PDE1A_HUMAN	P54750	CHEMBL3421	Phosphodiesterase 1A, Human	1
PDE1B_HUMAN	Q01064	CHEMBL4425	Phosphodiesterase 1B, Human	1
PDE1B_RAT	Q01066	CHEMBL3665	Phosphodiesterase 1B, Rat	1
PDE1C_HUMAN	Q14123	CHEMBL4619	Phosphodiesterase 1C, Human	1
PDR5_YEAST	P33302	CHEMBL1697658	Pleiotropic ABC Efflux Transporter Of Multiple Drugs, Yeast	1
PLD1_HUMAN	Q13393	CHEMBL2536	Phospholipase D1, Human	1
PLD2_HUMAN	O14939	CHEMBL2734	Phospholipase D2, Human	1
Q4U254_9ENTO	Q4U254	CHEMBL2857	Human Rhinovirus A Protease, 9ento	1
Q63380_RAT	Q63380	CHEMBL6184	Transporter, Rat	1
Q72874_9HIV1	Q72874	CHEMBL243	Human Immunodeficiency Virus Type 1 Protease, 9hiv1	1
Q8AWE3_CHICK	Q8AWE3	CHEMBL2669	Serine-threonine Protein Phosphatase 2A Regulatory Subunit, Chick	1
SC6A3_RAT	P23977	CHEMBL338	Dopamine Transporter, Rat	1
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	1
THA_HUMAN	P10827	CHEMBL1860	Thyroid Hormone Receptor Alpha, Human	1
THB_HUMAN	P10828	CHEMBL1947	Thyroid Hormone Receptor Beta-1, Human	1
Z100267	Z100267	CHEMBL612409	Anti-estrogen Binding Site (AEBS)	1
Z104297	Z104297	CHEMBL1907603	Glutamate NMDA Receptor; GRIN1/GRIN2B	1
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	1
Z104303	Z104303	CHEMBL1907609	Muscarinic Acetylcholine Receptor	1