ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (750)
Reactome (4)
Related By:
Pathway (2)
Organism (2)
Gene (0)
Org. Clust. (5)
ChEMBL (106)
Rings (9)

Glutamate (NMDA) Receptor Subunit Zeta 1, Rat (750 Compounds)

Swissprot:: NMDZ1_RAT
Stitch:: NMDZ1_RAT
UniProt:: P35439
ChEMBL:: CHEMBL330
Reactome:: REACT_196392; REACT_241561; REACT_196389; REACT_258198
PDB:: 1PB7 (DOCK); 1PB8 (DOCK); 1PB9 (DOCK); 1PBQ (DOCK); 1Y1M (DOCK); 1Y1Z (DOCK); 1Y20 (DOCK); 2A5T (DOCK); 3Q41 (DOCK); Grin1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	750	48	16	15
Binding ≤ 1μM	537	31	11	14
Functional ≤ 10μM	138	27	6	7

Reactome ID	Description	Species
REACT_196392	CREB phosphorylation through the activation of CaMKII	Rattus norvegicus
REACT_241561	EPHB-mediated forward signaling	Rattus norvegicus
REACT_196389	Ras activation uopn Ca2+ infux through NMDA receptor	Rattus norvegicus
REACT_258198	Unblocking of NMDA receptor, glutamate binding and activation	Rattus norvegicus

Uniprot	Swissprot	Chembl	Description	Number Shared
NMDE3_RAT	Q00961	CHEMBL401	Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat	170

Ras activation uopn Ca2+ infux through NMDA receptor

Uniprot	Swissprot	Chembl	Description	Number Shared
NMDE3_RAT	Q00961	CHEMBL401	Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat	170

Unblocking of NMDA receptor, glutamate binding and activation

Uniprot	Swissprot	Chembl	Description	Number Shared
NMDE3_RAT	Q00961	CHEMBL401	Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat	170

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
NMDZ1_HUMAN	Q05586	CHEMBL2015	Glutamate (NMDA) Receptor Subunit Zeta 1, Human	412	60	22	20
NMDZ1_MOUSE	P35438	CHEMBL2895	Glutamate (NMDA) Receptor Subunit Zeta 1, Mouse	16	7	4	3

Clustered By Gene (0)

Clustered By Organism (5)

Code	Description	Substances	Purchasable	Natural	In Man
NMDZ1-1-E	Glutamate (NMDA) Receptor Subunit Zeta 1 (cluster #1 Of 6), Eukaryotic	47	7	2	1
NMDZ1-2-E	Glutamate (NMDA) Receptor Subunit Zeta 1 (cluster #2 Of 6), Eukaryotic	504	41	19	21
NMDZ1-3-E	Glutamate (NMDA) Receptor Subunit Zeta 1 (cluster #3 Of 6), Eukaryotic	464	17	2	3
NMDZ1-4-E	Glutamate (NMDA) Receptor Subunit Zeta 1 (cluster #4 Of 6), Eukaryotic	40	18	9	4
NMDZ1-5-E	Glutamate (NMDA) Receptor Subunit Zeta 1 (cluster #5 Of 6), Eukaryotic	5	4	1	0
NMDZ1-6-E	Glutamate (NMDA) Receptor Subunit Zeta 1 (cluster #6 Of 6), Eukaryotic	30	6	1	1

Uniprot	Swissprot	Chembl	Description	Number Shared
NMDE2_RAT	Q00960	CHEMBL311	Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat	307
NMDE3_RAT	Q00961	CHEMBL401	Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat	167
NMDE4_RAT	Q62645	CHEMBL303	Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat	162
NMD3B_RAT	Q8VHN2	CHEMBL282	Glutamate [NMDA] Receptor Subunit 3B, Rat	156
GRIA1_MOUSE	P23818	CHEMBL3502	Glutamate Receptor Ionotropic, AMPA 1, Mouse	152
GRIA2_RAT	P19491	CHEMBL3503	Glutamate Receptor Ionotropic, AMPA 2, Rat	152
GRIA3_RAT	P19492	CHEMBL3504	Glutamate Receptor Ionotropic, AMPA 3, Rat	152
GRIA4_RAT	P19493	CHEMBL3505	Glutamate Receptor Ionotropic, AMPA 4, Rat	152
NMDE1_RAT	Q00959	CHEMBL310	Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat	134
NMD3A_RAT	Q9R1M7	CHEMBL342	Glutamate [NMDA] Receptor Subunit 3A, Rat	133
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	105
NMDZ1_HUMAN	Q05586	CHEMBL2015	Glutamate (NMDA) Receptor Subunit Zeta 1, Human	91
NMDE2_HUMAN	Q13224	CHEMBL1904	Glutamate [NMDA] Receptor Subunit Epsilon 2, Human	89
NMD3A_HUMAN	Q8TCU5	CHEMBL4787	Glutamate [NMDA] Receptor Subunit 3A, Human	88
NMD3B_HUMAN	O60391	CHEMBL2913	Glutamate [NMDA] Receptor Subunit 3B, Human	88
NMDE1_HUMAN	Q12879	CHEMBL1972	Glutamate [NMDA] Receptor Subunit Epsilon 1, Human	88
NMDE3_HUMAN	Q14957	CHEMBL4109	Glutamate [NMDA] Receptor Subunit Epsilon 3, Human	88
NMDE4_HUMAN	O15399	CHEMBL2591	Glutamate [NMDA] Receptor Subunit Epsilon 4, Human	88
GRID1_HUMAN	Q9ULK0	CHEMBL2936	Glutamate Receptor Delta-1 Subunit, Human	46
GRIK1_RAT	P22756	CHEMBL2919	Glutamate Receptor Ionotropic Kainate 1, Rat	27
GRIK2_RAT	P42260	CHEMBL3607	Glutamate Receptor Ionotropic Kainate 2, Rat	27
GRIK3_RAT	P42264	CHEMBL3744	Glutamate Receptor Ionotropic Kainate 3, Rat	27
GRIK4_RAT	Q01812	CHEMBL3044	Glutamate Receptor Ionotropic Kainate 4, Rat	27
GRIK5_RAT	Q63273	CHEMBL4041	Glutamate Receptor Ionotropic Kainate 5, Rat	27
GRINA_HUMAN	Q7Z429	CHEMBL4704	Glutamate [NMDA] Receptor Associated Protein 1, Human	27
Z104304	Z104304	CHEMBL1907610	Adrenergic Receptor Alpha-1	23
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	20
GRL1A_RAT	Q91XQ4	CHEMBL3059	Glutamate [NMDA] Receptor-like 1A, Rat	13
ACM1_RAT	P08482	CHEMBL276	Muscarinic Acetylcholine Receptor M1, Rat	11
GRIA1_HUMAN	P42261	CHEMBL2009	Glutamate Receptor Ionotropic, AMPA 1, Human	10
GRIA1_RAT	P19490	CHEMBL3753	Glutamate Receptor Ionotropic, AMPA 1, Rat	10
GRIA2_HUMAN	P42262	CHEMBL4016	Glutamate Receptor Ionotropic, AMPA 2, Human	10
GRIA3_HUMAN	P42263	CHEMBL3595	Glutamate Receptor Ionotropic, AMPA 3, Human	10
GRIA4_HUMAN	P48058	CHEMBL3190	Glutamate Receptor Ionotropic, AMPA 4, Human	10
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	6
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	6
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	6
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	6
A2AIR5_MOUSE	A2AIR5	CHEMBL2562	Glutamate [NMDA] Receptor Subunit 3A, Mouse	5
NMD3B_MOUSE	Q91ZU9	CHEMBL2557	Glutamate [NMDA] Receptor Subunit 3B, Mouse	5
NMDE1_MOUSE	P35436	CHEMBL2521	Glutamate [NMDA] Receptor Subunit Epsilon 1, Mouse	5
NMDE2_MOUSE	Q01097	CHEMBL3442	Glutamate [NMDA] Receptor Subunit Epsilon 2, Mouse	5
NMDE3_MOUSE	Q01098	CHEMBL3555	Glutamate [NMDA] Receptor Subunit Epsilon 3, Mouse	5
NMDE4_MOUSE	Q03391	CHEMBL2893	Glutamate [NMDA] Receptor Subunit Epsilon 4, Mouse	5
NMDZ1_MOUSE	P35438	CHEMBL2895	Glutamate (NMDA) Receptor Subunit Zeta 1, Mouse	5
Z104297	Z104297	CHEMBL1907603	Glutamate NMDA Receptor; GRIN1/GRIN2B	5
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	4
GLRA1_RAT	P07727	CHEMBL3246	Glycine Receptor Alpha-1 Chain, Rat	4
GLRA2_RAT	P22771	CHEMBL2328	Glycine Receptor Alpha-2 Chain, Rat	4
GLRA3_RAT	P24524	CHEMBL2677	Glycine Receptor Alpha-3 Chain, Rat	4
GLRB_RAT	P20781	CHEMBL4126	Glycine Receptor Beta Chain, Rat	4
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	3
TRPV1_RAT	O35433	CHEMBL5102	Vanilloid Receptor, Rat	3
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a Adrenergic Receptor, Human	2
EGFR_HUMAN	P00533	CHEMBL203	Epidermal Growth Factor Receptor ErbB1, Human	2
F16P1_HUMAN	P09467	CHEMBL3975	Fructose-1,6-bisphosphatase, Human	2
F16P2_HUMAN	O00757	CHEMBL3877	Fructose-1,6-bisphosphatase 2, Human	2
GLRA4_MOUSE	Q61603	CHEMBL3500	Glycine Receptor Alpha-4 Chain, Mouse	2
GRIK1_HUMAN	P39086	CHEMBL1918	Glutamate Receptor Ionotropic Kainate 1, Human	2
GRIK2_HUMAN	Q13002	CHEMBL3683	Glutamate Receptor Ionotropic Kainate 2, Human	2
GRIK3_HUMAN	Q13003	CHEMBL3684	Glutamate Receptor Ionotropic Kainate 3, Human	2
GRIK5_HUMAN	Q16478	CHEMBL2675	Glutamate Receptor Ionotropic Kainate 5, Human	2
PCP_HUMAN	P42785	CHEMBL2335	Lysosomal Pro-X Carboxypeptidase, Human	2
Z104298	Z104298	CHEMBL1907604	Glutamate NMDA Receptor; GRIN1/GRIN2A	2
Z50594	Z50594	CHEMBL375	Mus Musculus	2
Z80951	Z80951	CHEMBL614822	NIH3T3 (Fibroblasts)	2
5HT1A_MOUSE	Q64264	CHEMBL3737	Serotonin 1a (5-HT1a) Receptor, Mouse	1
5HT2A_BOVIN	Q75Z89	CHEMBL3446	Serotonin 2a (5-HT2a) Receptor, Bovin	1
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic Acetylcholine Receptor M1, Human	1
ACM1_MOUSE	P12657	CHEMBL3733	Muscarinic Acetylcholine Receptor M1, Mouse	1
ACM2_MOUSE	Q9ERZ4	CHEMBL3197	Muscarinic Acetylcholine Receptor M2, Mouse	1
ACM3_MOUSE	Q9ERZ3	CHEMBL5105	Muscarinic Acetylcholine Receptor M3, Mouse	1
ACM4_MOUSE	P32211	CHEMBL4572	Muscarinic Acetylcholine Receptor M4, Mouse	1
ACM5_MOUSE	Q920H4	CHEMBL2324	Muscarinic Acetylcholine Receptor M5, Mouse	1
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	1
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	1
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	1
CHLE_MOUSE	Q03311	CHEMBL2528	Butyrylcholinesterase, Mouse	1
DRD2_BOVIN	P20288	CHEMBL3998	Dopamine D2 Receptor, Bovin	1
EAA3_HUMAN	P43005	CHEMBL2721	Excitatory Amino Acid Transporter 3, Human	1
EBP_CAVPO	Q60490	CHEMBL5525	3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Guinea Pig	1
EBP_HUMAN	Q15125	CHEMBL4931	3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human	1
ERG2_YEAST	P32352	CHEMBL3224	C-8 Sterol Isomerase, Yeast	1
F16P1_PIG	P00636	CHEMBL2263	Fructose-1,6-bisphosphatase, Pig	1
GNRHR_RAT	P30969	CHEMBL3066	Gonadotropin-releasing Hormone Receptor, Rat	1
GRIK4_HUMAN	Q16099	CHEMBL2829	Glutamate Receptor Ionotropic Kainate 4, Human	1
GRM1_HUMAN	Q13255	CHEMBL3772	Metabotropic Glutamate Receptor 1, Human	1
GRM1_RAT	P23385	CHEMBL4477	Metabotropic Glutamate Receptor 1, Rat	1
GRM2_HUMAN	Q14416	CHEMBL5137	Metabotropic Glutamate Receptor 2, Human	1
GRM2_RAT	P31421	CHEMBL2851	Metabotropic Glutamate Receptor 2, Rat	1
GRM3_HUMAN	Q14832	CHEMBL2888	Metabotropic Glutamate Receptor 3, Human	1
GRM3_RAT	P31422	CHEMBL3067	Metabotropic Glutamate Receptor 3, Rat	1
GRM4_HUMAN	Q14833	CHEMBL2736	Metabotropic Glutamate Receptor 4, Human	1
GRM4_RAT	P31423	CHEMBL2787	Metabotropic Glutamate Receptor 4, Rat	1
GRM5_HUMAN	P41594	CHEMBL3227	Metabotropic Glutamate Receptor 5, Human	1
GRM5_RAT	P31424	CHEMBL2564	Metabotropic Glutamate Receptor 5, Rat	1
GRM6_RAT	P35349	CHEMBL3842	Metabotropic Glutamate Receptor 6, Rat	1
GRM8_HUMAN	O00222	CHEMBL3228	Metabotropic Glutamate Receptor 8, Human	1
GRM8_MOUSE	P47743	CHEMBL4626	Metabotropic Glutamate Receptor 8, Mouse	1
GRM8_RAT	P70579	CHEMBL2718	Metabotropic Glutamate Receptor 8, Rat	1
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	1
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	1
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	1
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	1
Z50587	Z50587	CHEMBL372	Homo Sapiens	1
Z80390	Z80390	CHEMBL390	PC-3 (Prostate Carcinoma Cells)	1