ZINC 12

User Information

Not Authenticated — sign in

Active cart: Temporary Cart (0 items)

Navigation

About
- ZINC
- BCIRC
- Irwin Lab
- Shoichet Lab
- UCSF
- Acknowledgements
- Facts
- Usage
Search
- By:
- Text
- Structure
- Properties
- Catalogs
- ZINC
- Targets
- Rings
- Combination
Subsets
- By:
- Catalog
- Property
- Target
- Ring
- Cart
Help
- Introduction
- FAQ
- Scripting/API
- Quick Search
- Problems
- Filtering
- History
Social
- ZINC Fans
- Decoy Club
- DOCK Fans
- Facebook
- Twitter
- Blog
- Linkedin
Quick Search ZINC ID or SMILES

Names
Compounds (132)
Reactome (2)
Related By:
Pathway (2)
Organism (1)
Gene (4)
Org. Clust. (2)
ChEMBL (72)
Rings (10)

Glutamate Receptor Ionotropic Kainate 1, Rat (132 Compounds)

Swissprot:: GRIK1_RAT
Stitch:: GRIK1_RAT
UniProt:: P22756
ChEMBL:: CHEMBL2919
Reactome:: REACT_196422; REACT_196426
PDB:: 1TXF (DOCK); 1VSO (DOCK); 1YCJ (DOCK); 2F34 (DOCK); 2F35 (DOCK); 2F36 (DOCK); 2OJT (DOCK); 2PBW (DOCK); 2QS1 (DOCK); 2QS2 (DOCK); 2QS3 (DOCK); 2QS4 (DOCK); 2WKY (DOCK); 3C31 (DOCK); 3C32 (DOCK); 3C33 (DOCK); 3C34 (DOCK); 3C35 (DOCK); 3C36 (DOCK); 3GBA (DOCK); 3GBB (DOCK); 3S2V (DOCK); Grik1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	132	28	16	19
Binding ≤ 1μM	66	16	13	17
Functional ≤ 10μM	57	13	4	3

Reactome ID	Description	Species
REACT_196422	Activation of Ca-permeable Kainate Receptor	Rattus norvegicus
REACT_196426	Activation of Na-permeable Kainate Receptors	Rattus norvegicus

Uniprot	Swissprot	Chembl	Description	Number Shared
GRIK4_RAT	Q01812	CHEMBL3044	Glutamate Receptor Ionotropic Kainate 4, Rat	108
GRIK5_RAT	Q63273	CHEMBL4041	Glutamate Receptor Ionotropic Kainate 5, Rat	111

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
GRIK1_HUMAN	P39086	CHEMBL1918	Glutamate Receptor Ionotropic Kainate 1, Human	135	26	10	8

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
GRIK2_RAT	P42260	CHEMBL3607	Glutamate Receptor Ionotropic Kainate 2, Rat	121	20	15	13
GRIK3_RAT	P42264	CHEMBL3744	Glutamate Receptor Ionotropic Kainate 3, Rat	105	24	16	14
GRIK4_RAT	Q01812	CHEMBL3044	Glutamate Receptor Ionotropic Kainate 4, Rat	91	19	14	13
GRIK5_RAT	Q63273	CHEMBL4041	Glutamate Receptor Ionotropic Kainate 5, Rat	90	19	14	13

Clustered By Gene (0)

Clustered By Organism (2)

Code	Description	Substances	Purchasable	Natural	In Man
GRIK1-1-E	Glutamate Receptor Ionotropic Kainate 1 (cluster #1 Of 3), Eukaryotic	37	9	6	6
GRIK1-2-E	Glutamate Receptor Ionotropic Kainate 1 (cluster #2 Of 3), Eukaryotic	115	21	2	1
GRIK1-3-E	Glutamate Receptor Ionotropic Kainate 1 (cluster #3 Of 3), Eukaryotic	100	14	12	14

Uniprot	Swissprot	Chembl	Description	Number Shared
GRIK3_RAT	P42264	CHEMBL3744	Glutamate Receptor Ionotropic Kainate 3, Rat	122
GRIK2_RAT	P42260	CHEMBL3607	Glutamate Receptor Ionotropic Kainate 2, Rat	115
GRIK5_RAT	Q63273	CHEMBL4041	Glutamate Receptor Ionotropic Kainate 5, Rat	111
GRIK4_RAT	Q01812	CHEMBL3044	Glutamate Receptor Ionotropic Kainate 4, Rat	108
GRIA2_RAT	P19491	CHEMBL3503	Glutamate Receptor Ionotropic, AMPA 2, Rat	97
GRIA3_RAT	P19492	CHEMBL3504	Glutamate Receptor Ionotropic, AMPA 3, Rat	91
GRIA4_RAT	P19493	CHEMBL3505	Glutamate Receptor Ionotropic, AMPA 4, Rat	86
GRIA1_MOUSE	P23818	CHEMBL3502	Glutamate Receptor Ionotropic, AMPA 1, Mouse	64
GRIA1_RAT	P19490	CHEMBL3753	Glutamate Receptor Ionotropic, AMPA 1, Rat	43
GRIA2_HUMAN	P42262	CHEMBL4016	Glutamate Receptor Ionotropic, AMPA 2, Human	31
GRIA1_HUMAN	P42261	CHEMBL2009	Glutamate Receptor Ionotropic, AMPA 1, Human	29
GRIA4_HUMAN	P48058	CHEMBL3190	Glutamate Receptor Ionotropic, AMPA 4, Human	27
NMDZ1_RAT	P35439	CHEMBL330	Glutamate (NMDA) Receptor Subunit Zeta 1, Rat	27
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	23
GRIK1_HUMAN	P39086	CHEMBL1918	Glutamate Receptor Ionotropic Kainate 1, Human	21
GRIA3_HUMAN	P42263	CHEMBL3595	Glutamate Receptor Ionotropic, AMPA 3, Human	20
GRIK5_HUMAN	Q16478	CHEMBL2675	Glutamate Receptor Ionotropic Kainate 5, Human	17
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	14
GRIK2_HUMAN	Q13002	CHEMBL3683	Glutamate Receptor Ionotropic Kainate 2, Human	10
GRIK3_HUMAN	Q13003	CHEMBL3684	Glutamate Receptor Ionotropic Kainate 3, Human	8
GRIK4_HUMAN	Q16099	CHEMBL2829	Glutamate Receptor Ionotropic Kainate 4, Human	5
GRIA2_MOUSE	P23819	CHEMBL3205	Glutamate Receptor Ionotropic, AMPA 2, Mouse	4
GRIA3_MOUSE	Q9Z2W9	CHEMBL3624	Glutamate Receptor Ionotropic, AMPA 3, Mouse	4
GRIA4_MOUSE	Q9Z2W8	CHEMBL3615	Glutamate Receptor Ionotropic, AMPA 4, Mouse	4
GRM1_HUMAN	Q13255	CHEMBL3772	Metabotropic Glutamate Receptor 1, Human	4
GRM1_RAT	P23385	CHEMBL4477	Metabotropic Glutamate Receptor 1, Rat	4
GRM3_RAT	P31422	CHEMBL3067	Metabotropic Glutamate Receptor 3, Rat	4
GRM5_RAT	P31424	CHEMBL2564	Metabotropic Glutamate Receptor 5, Rat	4
EAA3_HUMAN	P43005	CHEMBL2721	Excitatory Amino Acid Transporter 3, Human	3
GRM2_RAT	P31421	CHEMBL2851	Metabotropic Glutamate Receptor 2, Rat	3
GRM5_HUMAN	P41594	CHEMBL3227	Metabotropic Glutamate Receptor 5, Human	3
Z50574	Z50574	CHEMBL612667	Xenopus Sp.	3
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	2
GLRA1_RAT	P07727	CHEMBL3246	Glycine Receptor Alpha-1 Chain, Rat	2
GLRA2_RAT	P22771	CHEMBL2328	Glycine Receptor Alpha-2 Chain, Rat	2
GLRA3_RAT	P24524	CHEMBL2677	Glycine Receptor Alpha-3 Chain, Rat	2
GLRB_RAT	P20781	CHEMBL4126	Glycine Receptor Beta Chain, Rat	2
GRM2_HUMAN	Q14416	CHEMBL5137	Metabotropic Glutamate Receptor 2, Human	2
GRM4_HUMAN	Q14833	CHEMBL2736	Metabotropic Glutamate Receptor 4, Human	2
GRM8_MOUSE	P47743	CHEMBL4626	Metabotropic Glutamate Receptor 8, Mouse	2
NMDE1_RAT	Q00959	CHEMBL310	Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat	2
NMDE2_RAT	Q00960	CHEMBL311	Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat	2
NMDE4_RAT	Q62645	CHEMBL303	Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat	2
FOLH1_HUMAN	Q04609	CHEMBL1892	Glutamate Carboxypeptidase II, Human	1
GLRA4_MOUSE	Q61603	CHEMBL3500	Glycine Receptor Alpha-4 Chain, Mouse	1
GRIK2_XENLA	Q91755	CHEMBL3395	Glutamate Receptor Ionotropic Kainate 2, Xenla	1
GRM1_MOUSE	P97772	CHEMBL2892	Metabotropic Glutamate Receptor 1, Mouse	1
GRM3_HUMAN	Q14832	CHEMBL2888	Metabotropic Glutamate Receptor 3, Human	1
GRM3_MOUSE	Q9QYS2	CHEMBL3824	Metabotropic Glutamate Receptor 3, Mouse	1
GRM4_RAT	P31423	CHEMBL2787	Metabotropic Glutamate Receptor 4, Rat	1
GRM6_HUMAN	O15303	CHEMBL4573	Metabotropic Glutamate Receptor 6, Human	1
GRM6_RAT	P35349	CHEMBL3842	Metabotropic Glutamate Receptor 6, Rat	1
GRM7_MOUSE	Q68ED2	CHEMBL3966	Metabotropic Glutamate Receptor 7, Mouse	1
GRM8_HUMAN	O00222	CHEMBL3228	Metabotropic Glutamate Receptor 8, Human	1
GRM8_RAT	P70579	CHEMBL2718	Metabotropic Glutamate Receptor 8, Rat	1
MURI_HELPY	P56068	CHEMBL6078	Glutamate Racemase, Helpy	1
NMD3A_HUMAN	Q8TCU5	CHEMBL4787	Glutamate [NMDA] Receptor Subunit 3A, Human	1
NMD3A_RAT	Q9R1M7	CHEMBL342	Glutamate [NMDA] Receptor Subunit 3A, Rat	1
NMD3B_HUMAN	O60391	CHEMBL2913	Glutamate [NMDA] Receptor Subunit 3B, Human	1
NMD3B_RAT	Q8VHN2	CHEMBL282	Glutamate [NMDA] Receptor Subunit 3B, Rat	1
NMDE1_HUMAN	Q12879	CHEMBL1972	Glutamate [NMDA] Receptor Subunit Epsilon 1, Human	1
NMDE2_HUMAN	Q13224	CHEMBL1904	Glutamate [NMDA] Receptor Subunit Epsilon 2, Human	1
NMDE3_HUMAN	Q14957	CHEMBL4109	Glutamate [NMDA] Receptor Subunit Epsilon 3, Human	1
NMDE3_RAT	Q00961	CHEMBL401	Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat	1
NMDE4_HUMAN	O15399	CHEMBL2591	Glutamate [NMDA] Receptor Subunit Epsilon 4, Human	1
NMDZ1_HUMAN	Q05586	CHEMBL2015	Glutamate (NMDA) Receptor Subunit Zeta 1, Human	1
Q80T35_MOUSE	Q80T35	CHEMBL3033	Metabotropic Glutamate Receptor 6, Mouse	1
Q80T43_MOUSE	Q80T43	CHEMBL3779	Metabotropic Glutamate Receptor 2, Mouse	1
Q80T47_MOUSE	Q80T47	CHEMBL2832	Metabotropic Glutamate Receptor 5, Mouse	1
XCT_HUMAN	Q9UPY5	CHEMBL1075149	Cystine/glutamate Transporter, Human	1
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	1
Z50594	Z50594	CHEMBL375	Mus Musculus	1