UCSF

Excitatory Amino Acid Transporter 3, Human (70 Compounds)

Swissprot:
EAA3_HUMAN
Stitch:
EAA3_HUMAN
UniProt:
P43005
ChEMBL:
CHEMBL2721
Reactome:
REACT_12591
REACT_19397
PDB:
SLC1A1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 70 8 1 1
Binding ≤ 1μM 33 2 1 1
Functional ≤ 10μM 2 1 1 1

Reactome Network (2)

Reactome ID Description Species
REACT_12591 Glutamate Neurotransmitter Release Cycle Homo sapiens
REACT_19397 Transport of inorganic cations/anions and amino acids/oligopeptides Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
EAA4_HUMAN P48664 CHEMBL3173 Excitatory Amino Acid Transporter 4, Human 2
EAA5_HUMAN O00341 CHEMBL4390 Excitatory Amino Acid Transporter 5, Human 2

Transport of inorganic cations/anions and amino acids/oligopeptides

Uniprot Swissprot Chembl Description Number Shared
EAA1_HUMAN P43003 CHEMBL3085 Excitatory Amino Acid Transporter 1, Human 51
EAA2_HUMAN P43004 CHEMBL4973 Excitatory Amino Acid Transporter 2, Human 60
EAA4_HUMAN P48664 CHEMBL3173 Excitatory Amino Acid Transporter 4, Human 2
EAA5_HUMAN O00341 CHEMBL4390 Excitatory Amino Acid Transporter 5, Human 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
EAA3_RAT P51907 CHEMBL3113 Excitatory Amino Acid Transporter 3, Rat 11 2 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
EAA1_HUMAN P43003 CHEMBL3085 Excitatory Amino Acid Transporter 1, Human 129 66 0 0
EAA2_HUMAN P43004 CHEMBL4973 Excitatory Amino Acid Transporter 2, Human 66 9 1 0
EAA4_HUMAN P48664 CHEMBL3173 Excitatory Amino Acid Transporter 4, Human 2 1 0 0
EAA5_HUMAN O00341 CHEMBL4390 Excitatory Amino Acid Transporter 5, Human 2 1 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
EAA3-1-E Excitatory Amino Acid Transporter 3 (cluster #1 Of 2), Eukaryotic 76 10 0 0
EAA3-2-E Excitatory Amino Acid Transporter 3 (cluster #2 Of 2), Eukaryotic 8 1 1 1
Uniprot Swissprot Chembl Description Number Shared
EAA2_HUMAN P43004 CHEMBL4973 Excitatory Amino Acid Transporter 2, Human 60
EAA1_HUMAN P43003 CHEMBL3085 Excitatory Amino Acid Transporter 1, Human 51
GRIK1_RAT P22756 CHEMBL2919 Glutamate Receptor Ionotropic Kainate 1, Rat 3
EAA1_RAT P24942 CHEMBL4190 Excitatory Amino Acid Transporter 1, Rat 2
EAA2_RAT P31596 CHEMBL2900 Excitatory Amino Acid Transporter 2, Rat 2
EAA3_RAT P51907 CHEMBL3113 Excitatory Amino Acid Transporter 3, Rat 2
EAA4_HUMAN P48664 CHEMBL3173 Excitatory Amino Acid Transporter 4, Human 2
EAA5_HUMAN O00341 CHEMBL4390 Excitatory Amino Acid Transporter 5, Human 2
GRIK2_RAT P42260 CHEMBL3607 Glutamate Receptor Ionotropic Kainate 2, Rat 2
GRIK3_RAT P42264 CHEMBL3744 Glutamate Receptor Ionotropic Kainate 3, Rat 2
SATT_HUMAN P43007 CHEMBL2315 Neutral Amino Acid Transporter A, Human 2
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 1
GRIA1_HUMAN P42261 CHEMBL2009 Glutamate Receptor Ionotropic, AMPA 1, Human 1
GRIA1_MOUSE P23818 CHEMBL3502 Glutamate Receptor Ionotropic, AMPA 1, Mouse 1
GRIA1_RAT P19490 CHEMBL3753 Glutamate Receptor Ionotropic, AMPA 1, Rat 1
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate Receptor Ionotropic, AMPA 2, Human 1
GRIA2_RAT P19491 CHEMBL3503 Glutamate Receptor Ionotropic, AMPA 2, Rat 1
GRIA3_RAT P19492 CHEMBL3504 Glutamate Receptor Ionotropic, AMPA 3, Rat 1
GRIA4_HUMAN P48058 CHEMBL3190 Glutamate Receptor Ionotropic, AMPA 4, Human 1
GRIA4_RAT P19493 CHEMBL3505 Glutamate Receptor Ionotropic, AMPA 4, Rat 1
GRIK1_HUMAN P39086 CHEMBL1918 Glutamate Receptor Ionotropic Kainate 1, Human 1
GRIK2_HUMAN Q13002 CHEMBL3683 Glutamate Receptor Ionotropic Kainate 2, Human 1
GRIK3_HUMAN Q13003 CHEMBL3684 Glutamate Receptor Ionotropic Kainate 3, Human 1
GRIK4_RAT Q01812 CHEMBL3044 Glutamate Receptor Ionotropic Kainate 4, Rat 1
GRIK5_HUMAN Q16478 CHEMBL2675 Glutamate Receptor Ionotropic Kainate 5, Human 1
GRIK5_RAT Q63273 CHEMBL4041 Glutamate Receptor Ionotropic Kainate 5, Rat 1
GRM1_HUMAN Q13255 CHEMBL3772 Metabotropic Glutamate Receptor 1, Human 1
GRM1_RAT P23385 CHEMBL4477 Metabotropic Glutamate Receptor 1, Rat 1
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic Glutamate Receptor 2, Human 1
GRM2_RAT P31421 CHEMBL2851 Metabotropic Glutamate Receptor 2, Rat 1
GRM3_RAT P31422 CHEMBL3067 Metabotropic Glutamate Receptor 3, Rat 1
GRM4_HUMAN Q14833 CHEMBL2736 Metabotropic Glutamate Receptor 4, Human 1
GRM4_RAT P31423 CHEMBL2787 Metabotropic Glutamate Receptor 4, Rat 1
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 1
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 1
GRM6_HUMAN O15303 CHEMBL4573 Metabotropic Glutamate Receptor 6, Human 1
GRM6_RAT P35349 CHEMBL3842 Metabotropic Glutamate Receptor 6, Rat 1
GRM8_HUMAN O00222 CHEMBL3228 Metabotropic Glutamate Receptor 8, Human 1
GRM8_MOUSE P47743 CHEMBL4626 Metabotropic Glutamate Receptor 8, Mouse 1
GRM8_RAT P70579 CHEMBL2718 Metabotropic Glutamate Receptor 8, Rat 1
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1

Most Common Rings