UCSF

Metabotropic Glutamate Receptor 6, Human (4 Compounds)

Swissprot:
GRM6_HUMAN
Stitch:
GRM6_HUMAN
UniProt:
O15303
ChEMBL:
CHEMBL4573
Reactome:
REACT_18319
REACT_19231
PDB:
GRM6

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 4 3 1 1
Binding ≤ 1μM 2 2 0 0
Functional ≤ 10μM 25 13 5 4

Reactome Network (2)

Reactome ID Description Species
REACT_18319 Class C/3 (Metabotropic glutamate/pheromone receptors) Homo sapiens
REACT_19231 G alpha (i) signalling events Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
GRM1_HUMAN Q13255 CHEMBL3772 Metabotropic Glutamate Receptor 1, Human 3
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic Glutamate Receptor 2, Human 9
GRM3_HUMAN Q14832 CHEMBL2888 Metabotropic Glutamate Receptor 3, Human 9
GRM4_HUMAN Q14833 CHEMBL2736 Metabotropic Glutamate Receptor 4, Human 7
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 4
GRM8_HUMAN O00222 CHEMBL3228 Metabotropic Glutamate Receptor 8, Human 11

G alpha (i) signalling events

Uniprot Swissprot Chembl Description Number Shared
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic Glutamate Receptor 2, Human 9
GRM3_HUMAN Q14832 CHEMBL2888 Metabotropic Glutamate Receptor 3, Human 9
GRM4_HUMAN Q14833 CHEMBL2736 Metabotropic Glutamate Receptor 4, Human 7
GRM8_HUMAN O00222 CHEMBL3228 Metabotropic Glutamate Receptor 8, Human 11
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GRM6_RAT P35349 CHEMBL3842 Metabotropic Glutamate Receptor 6, Rat 8 5 2 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GRM1_HUMAN Q13255 CHEMBL3772 Metabotropic Glutamate Receptor 1, Human 51 12 6 4
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic Glutamate Receptor 2, Human 293 14 4 3
GRM3_HUMAN Q14832 CHEMBL2888 Metabotropic Glutamate Receptor 3, Human 14 5 2 2
GRM4_HUMAN Q14833 CHEMBL2736 Metabotropic Glutamate Receptor 4, Human 137 45 3 3
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 523 45 4 4
GRM8_HUMAN O00222 CHEMBL3228 Metabotropic Glutamate Receptor 8, Human 5 3 1 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
GRM8_HUMAN O00222 CHEMBL3228 Metabotropic Glutamate Receptor 8, Human 11
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic Glutamate Receptor 2, Human 9
GRM3_HUMAN Q14832 CHEMBL2888 Metabotropic Glutamate Receptor 3, Human 9
GRM4_HUMAN Q14833 CHEMBL2736 Metabotropic Glutamate Receptor 4, Human 7
GRM4_RAT P31423 CHEMBL2787 Metabotropic Glutamate Receptor 4, Rat 4
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 4
GRM6_RAT P35349 CHEMBL3842 Metabotropic Glutamate Receptor 6, Rat 4
GRM8_RAT P70579 CHEMBL2718 Metabotropic Glutamate Receptor 8, Rat 4
GRM1_HUMAN Q13255 CHEMBL3772 Metabotropic Glutamate Receptor 1, Human 3
GRM2_RAT P31421 CHEMBL2851 Metabotropic Glutamate Receptor 2, Rat 3
GRM3_RAT P31422 CHEMBL3067 Metabotropic Glutamate Receptor 3, Rat 3
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 3
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 2
MDR1_MOUSE P06795 CHEMBL3467 P-glycoprotein 1, Mouse 2
MDR3_MOUSE P21447 CHEMBL2573 P-glycoprotein 3, Mouse 2
Z102121 Z102121 CHEMBL613162 Trichophyton Mentagrophytes 2
Z50038 Z50038 CHEMBL612328 Plasmodium Yoelii Yoelii 2
Z50046 Z50046 CHEMBL612334 Trichophyton Quinckeanum 2
Z50408 Z50408 CHEMBL612841 Issatchenkia Orientalis 2
Z50409 Z50409 CHEMBL612842 Kluyveromyces Marxianus 2
Z50416 Z50416 CHEMBL363 Aspergillus Fumigatus 2
Z50442 Z50442 CHEMBL366 Candida Albicans 2
Z50443 Z50443 CHEMBL612647 Candida Glabrata 2
Z50452 Z50452 CHEMBL612649 Trichophyton Rubrum 2
Z50459 Z50459 CHEMBL367 Leishmania Donovani 2
EAA3_HUMAN P43005 CHEMBL2721 Excitatory Amino Acid Transporter 3, Human 1
GRIA1_HUMAN P42261 CHEMBL2009 Glutamate Receptor Ionotropic, AMPA 1, Human 1
GRIA1_MOUSE P23818 CHEMBL3502 Glutamate Receptor Ionotropic, AMPA 1, Mouse 1
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate Receptor Ionotropic, AMPA 2, Human 1
GRIA2_RAT P19491 CHEMBL3503 Glutamate Receptor Ionotropic, AMPA 2, Rat 1
GRIA3_RAT P19492 CHEMBL3504 Glutamate Receptor Ionotropic, AMPA 3, Rat 1
GRIA4_HUMAN P48058 CHEMBL3190 Glutamate Receptor Ionotropic, AMPA 4, Human 1
GRIA4_RAT P19493 CHEMBL3505 Glutamate Receptor Ionotropic, AMPA 4, Rat 1
GRIK1_HUMAN P39086 CHEMBL1918 Glutamate Receptor Ionotropic Kainate 1, Human 1
GRIK1_RAT P22756 CHEMBL2919 Glutamate Receptor Ionotropic Kainate 1, Rat 1
GRIK2_HUMAN Q13002 CHEMBL3683 Glutamate Receptor Ionotropic Kainate 2, Human 1
GRIK2_RAT P42260 CHEMBL3607 Glutamate Receptor Ionotropic Kainate 2, Rat 1
GRIK3_HUMAN Q13003 CHEMBL3684 Glutamate Receptor Ionotropic Kainate 3, Human 1
GRIK3_RAT P42264 CHEMBL3744 Glutamate Receptor Ionotropic Kainate 3, Rat 1
GRIK4_RAT Q01812 CHEMBL3044 Glutamate Receptor Ionotropic Kainate 4, Rat 1
GRIK5_HUMAN Q16478 CHEMBL2675 Glutamate Receptor Ionotropic Kainate 5, Human 1
GRIK5_RAT Q63273 CHEMBL4041 Glutamate Receptor Ionotropic Kainate 5, Rat 1
GRM1_RAT P23385 CHEMBL4477 Metabotropic Glutamate Receptor 1, Rat 1
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 1
GRM8_MOUSE P47743 CHEMBL4626 Metabotropic Glutamate Receptor 8, Mouse 1
MURI_HELPY P56068 CHEMBL6078 Glutamate Racemase, Helpy 1
NMDE1_RAT Q00959 CHEMBL310 Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat 1
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 1
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 1
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1