UCSF

Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat (163 Compounds)

Swissprot:
NMDE4_RAT
Stitch:
NMDE4_RAT
UniProt:
Q62645
ChEMBL:
CHEMBL303
PDB:
3OEK (DOCK)
3OEL (DOCK)
3OEM (DOCK)
3OEN (DOCK)
Grin2d

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 163 25 10 12
Binding ≤ 1μM 127 23 8 9
Functional ≤ 10μM 37 11 0 1

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 358 58 22 20
NMDE4_MOUSE Q03391 CHEMBL2893 Glutamate [NMDA] Receptor Subunit Epsilon 4, Mouse 16 7 4 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
NMDE1_RAT Q00959 CHEMBL310 Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat 139 16 6 5
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 473 39 15 17
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 245 35 12 13

Clustered By Gene (0)

Clustered By Organism (5)

Code Description Substances Purchasable Natural In Man
NMDE4-1-E Glutamate [NMDA] Receptor Subunit Epsilon 4 (cluster #1 Of 6), Eukaryotic 8 3 1 0
NMDE4-2-E Glutamate [NMDA] Receptor Subunit Epsilon 4 (cluster #2 Of 6), Eukaryotic 87 25 11 7
NMDE4-3-E Glutamate [NMDA] Receptor Subunit Epsilon 4 (cluster #3 Of 6), Eukaryotic 163 27 14 17
NMDE4-4-E Glutamate [NMDA] Receptor Subunit Epsilon 4 (cluster #4 Of 6), Eukaryotic 5 3 2 3
NMDE4-5-E Glutamate [NMDA] Receptor Subunit Epsilon 4 (cluster #5 Of 6), Eukaryotic 208 15 3 4
NMDE4-6-E Glutamate [NMDA] Receptor Subunit Epsilon 4 (cluster #6 Of 6), Eukaryotic 30 5 0 0
Uniprot Swissprot Chembl Description Number Shared
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 181
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 170
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 162
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 140
NMDE1_RAT Q00959 CHEMBL310 Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat 135
NMD3A_RAT Q9R1M7 CHEMBL342 Glutamate [NMDA] Receptor Subunit 3A, Rat 82
GRIA1_MOUSE P23818 CHEMBL3502 Glutamate Receptor Ionotropic, AMPA 1, Mouse 38
GRIA2_RAT P19491 CHEMBL3503 Glutamate Receptor Ionotropic, AMPA 2, Rat 38
GRIA3_RAT P19492 CHEMBL3504 Glutamate Receptor Ionotropic, AMPA 3, Rat 38
GRIA4_RAT P19493 CHEMBL3505 Glutamate Receptor Ionotropic, AMPA 4, Rat 38
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 36
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 36
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 36
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 36
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 36
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 36
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 36
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 29
GRINA_HUMAN Q7Z429 CHEMBL4704 Glutamate [NMDA] Receptor Associated Protein 1, Human 27
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 20
GRL1A_RAT Q91XQ4 CHEMBL3059 Glutamate [NMDA] Receptor-like 1A, Rat 13
GRIA1_RAT P19490 CHEMBL3753 Glutamate Receptor Ionotropic, AMPA 1, Rat 7
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 7
A2AIR5_MOUSE A2AIR5 CHEMBL2562 Glutamate [NMDA] Receptor Subunit 3A, Mouse 6
NMD3B_MOUSE Q91ZU9 CHEMBL2557 Glutamate [NMDA] Receptor Subunit 3B, Mouse 6
NMDE1_MOUSE P35436 CHEMBL2521 Glutamate [NMDA] Receptor Subunit Epsilon 1, Mouse 6
NMDE2_MOUSE Q01097 CHEMBL3442 Glutamate [NMDA] Receptor Subunit Epsilon 2, Mouse 6
NMDE3_MOUSE Q01098 CHEMBL3555 Glutamate [NMDA] Receptor Subunit Epsilon 3, Mouse 6
NMDE4_MOUSE Q03391 CHEMBL2893 Glutamate [NMDA] Receptor Subunit Epsilon 4, Mouse 6
NMDZ1_MOUSE P35438 CHEMBL2895 Glutamate (NMDA) Receptor Subunit Zeta 1, Mouse 6
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 6
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 6
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 5
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 4
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 4
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 4
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 4
GRIA1_HUMAN P42261 CHEMBL2009 Glutamate Receptor Ionotropic, AMPA 1, Human 3
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate Receptor Ionotropic, AMPA 2, Human 3
GRIA4_HUMAN P48058 CHEMBL3190 Glutamate Receptor Ionotropic, AMPA 4, Human 3
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 3
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 3
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 3
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 3
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 2
GRIA3_HUMAN P42263 CHEMBL3595 Glutamate Receptor Ionotropic, AMPA 3, Human 2
GRIK1_HUMAN P39086 CHEMBL1918 Glutamate Receptor Ionotropic Kainate 1, Human 2
GRIK1_RAT P22756 CHEMBL2919 Glutamate Receptor Ionotropic Kainate 1, Rat 2
GRIK2_HUMAN Q13002 CHEMBL3683 Glutamate Receptor Ionotropic Kainate 2, Human 2
GRIK2_RAT P42260 CHEMBL3607 Glutamate Receptor Ionotropic Kainate 2, Rat 2
GRIK3_HUMAN Q13003 CHEMBL3684 Glutamate Receptor Ionotropic Kainate 3, Human 2
GRIK3_RAT P42264 CHEMBL3744 Glutamate Receptor Ionotropic Kainate 3, Rat 2
GRIK4_RAT Q01812 CHEMBL3044 Glutamate Receptor Ionotropic Kainate 4, Rat 2
GRIK5_HUMAN Q16478 CHEMBL2675 Glutamate Receptor Ionotropic Kainate 5, Human 2
GRIK5_RAT Q63273 CHEMBL4041 Glutamate Receptor Ionotropic Kainate 5, Rat 2
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 2
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 2
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 2
Z104298 Z104298 CHEMBL1907604 Glutamate NMDA Receptor; GRIN1/GRIN2A 2
Z50594 Z50594 CHEMBL375 Mus Musculus 2
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
GRIK4_HUMAN Q16099 CHEMBL2829 Glutamate Receptor Ionotropic Kainate 4, Human 1
GRM1_HUMAN Q13255 CHEMBL3772 Metabotropic Glutamate Receptor 1, Human 1
GRM1_RAT P23385 CHEMBL4477 Metabotropic Glutamate Receptor 1, Rat 1
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic Glutamate Receptor 2, Human 1
GRM2_RAT P31421 CHEMBL2851 Metabotropic Glutamate Receptor 2, Rat 1
GRM3_HUMAN Q14832 CHEMBL2888 Metabotropic Glutamate Receptor 3, Human 1
GRM3_RAT P31422 CHEMBL3067 Metabotropic Glutamate Receptor 3, Rat 1
GRM4_HUMAN Q14833 CHEMBL2736 Metabotropic Glutamate Receptor 4, Human 1
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 1
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 1
GRM6_HUMAN O15303 CHEMBL4573 Metabotropic Glutamate Receptor 6, Human 1
MURI_HELPY P56068 CHEMBL6078 Glutamate Racemase, Helpy 1
PCP_HUMAN P42785 CHEMBL2335 Lysosomal Pro-X Carboxypeptidase, Human 1
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 1

Most Common Rings