UCSF

Kappa Opioid Receptor, Mouse (125 Compounds)

Swissprot:
OPRK_MOUSE
Stitch:
OPRK_MOUSE
UniProt:
P33534
ChEMBL:
CHEMBL4329
Reactome:
REACT_250376
REACT_235286
PDB:
Oprk1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 125 13 9 8
Binding ≤ 1μM 107 10 7 6
Functional ≤ 10μM 35 2 2 1

Reactome Network (2)

Uniprot Swissprot Chembl Description Number Shared
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 88
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 103

Peptide ligand-binding receptors

Uniprot Swissprot Chembl Description Number Shared
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 88
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 103
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 482 25 19 19
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 3,585 110 54 58
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 568 51 34 45

Clustered By Gene (0)

Clustered By Organism (5)

Code Description Substances Purchasable Natural In Man
OPRK-1-E Kappa Opioid Receptor (cluster #1 Of 6), Eukaryotic 4,070 135 65 88
OPRK-2-E Kappa Opioid Receptor (cluster #2 Of 6), Eukaryotic 3 3 1 1
OPRK-3-E Kappa Opioid Receptor (cluster #3 Of 6), Eukaryotic 269 8 8 5
OPRK-4-E Kappa Opioid Receptor (cluster #4 Of 6), Eukaryotic 265 14 5 9
OPRK-5-E Kappa Opioid Receptor (cluster #5 Of 6), Eukaryotic 10 1 4 0
OPRK-6-E Kappa Opioid Receptor (cluster #6 Of 6), Eukaryotic 1 0 1 1
Uniprot Swissprot Chembl Description Number Shared
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 103
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 88
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 68
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 27
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 23
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 22
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 20
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 20
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 17
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 15
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 12
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 9
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 8
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 7
OPRM_BOVIN P79350 CHEMBL3041 Mu Opioid Receptor, Bovin 5
Z50512 Z50512 CHEMBL369 Cavia Porcellus 5
Z50594 Z50594 CHEMBL375 Mus Musculus 4
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 2
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 2
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 2
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 2
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 2
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 2
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 2
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 2
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 2
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 2
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 2
OPRX_HUMAN P41146 CHEMBL2014 Nociceptin Receptor, Human 2
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 2
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 1
OPRD_PIG P79291 CHEMBL4103 Delta Opioid Receptor, Pig 1
PDYN_HUMAN P01213 CHEMBL2227 Proenkephalin B, Human 1
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 1
SCN1A_RAT P04774 CHEMBL4906 Sodium Channel Protein Type I Alpha Subunit, Rat 1
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 1
SCN3A_RAT P08104 CHEMBL4966 Sodium Channel Protein Type III Alpha Subunit, Rat 1
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 1
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 1
UR2R_HUMAN Q9UKP6 CHEMBL3764 Urotensin II Receptor, Human 1
Z100254 Z100254 CHEMBL613295 Monoclonal Antibody (mAb) 3E7 1
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 1