UCSF

Cavia Porcellus (8 Compounds)

Swissprot:
Z50512
Stitch:
Z50512
UniProt:
Z50512
ChEMBL:
CHEMBL369

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 8 2 0 2
Binding ≤ 1μM 8 2 0 2
Functional ≤ 10μM 2,298 165 101 95
ADME/T ≤ 10μM 0 0 0 0

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z50594 Z50594 CHEMBL375 Mus Musculus 265
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 148
Z50587 Z50587 CHEMBL372 Homo Sapiens 83
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 82
ABCC8_HUMAN Q09428 CHEMBL2071 Sulfonylurea Receptor 1, Human 77
ABCC9_HUMAN O60706 CHEMBL1971 Sulfonylurea Receptor 2, Human 77
IRK11_HUMAN Q14654 CHEMBL1886 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 11, Human 77
IRK8_HUMAN Q15842 CHEMBL4770 Potassium Channel, Inwardly Rectifying, Subfamily J, Member 8, Human 77
CLTR1_HUMAN Q9Y271 CHEMBL1798 Cysteinyl Leukotriene Receptor 1, Human 48
CLTR2_HUMAN Q9NS75 CHEMBL4330 Cysteinyl Leukotriene Receptor 2, Human 38
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 38
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 35
CAC1C_HUMAN Q13936 CHEMBL1940 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human 32
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 32
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 32
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 32
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 30
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 27
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 27
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 27
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 20
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 19
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 19
BKRB2_HUMAN P30411 CHEMBL3157 Bradykinin B2 Receptor, Human 18
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 16
THAS_RAT P49430 CHEMBL4028 Thromboxane-A Synthase, Rat 15
Z80141 Z80141 CHEMBL614571 GH3 (Pituitary Adenoma Cells) 15
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 14
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 14
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 14
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 13
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 13
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 13
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 13
TRPV1_RAT O35433 CHEMBL5102 Vanilloid Receptor, Rat 13
TRPV2_RAT Q9WUD2 CHEMBL2863 Transient Receptor Potential Cation Channel Subfamily V Member 2, Rat 13
TRPV4_RAT Q9ERZ8 CHEMBL2775 Transient Receptor Potential Cation Channel Subfamily V Member 4, Rat 13
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 12
PDE4A_HUMAN P27815 CHEMBL254 Phosphodiesterase 4A, Human 12
PDE4C_HUMAN Q08493 CHEMBL291 Phosphodiesterase 4C, Human 12
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 9
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 8
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 7
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 7
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 7
PTAFR_HUMAN P25105 CHEMBL250 Platelet Activating Factor Receptor, Human 7
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 7
TA2R_RAT P34978 CHEMBL3156 Thromboxane A2 Receptor, Rat 7
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 6
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 6
ADRB2_RAT P10608 CHEMBL3754 Beta-2 Adrenergic Receptor, Rat 6
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 6
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 6
Z102306 Z102306 CHEMBL613606 Aorta 6
Z50590 Z50590 CHEMBL613488 Sus Scrofa 6
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 5
ADRB2_CANFA P54833 CHEMBL2289 Beta-2 Adrenergic Receptor, Canine 5
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 5
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 5
Z50588 Z50588 CHEMBL373 Canis Familiaris 5
Z80566 Z80566 CHEMBL612794 U-937 (Histiocytic Lymphoma Cells) 5
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 4
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 4
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 4
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 4
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 4
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 4
Z50466 Z50466 CHEMBL368 Trypanosoma Cruzi 4
AA2BR_RAT P29276 CHEMBL2592 Adenosine A2b Receptor, Rat 3
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 3
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 3
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 3
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 3
CAC1D_RAT P27732 CHEMBL4132 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat 3
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 3
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase, Rat 3
NK3R_HUMAN P29371 CHEMBL4429 Neurokinin 3 Receptor, Human 3
TRPA1_MOUSE Q8BLA8 CHEMBL1075310 Transient Receptor Potential Cation Channel Subfamily A Member 1, Mouse 3
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 3
AA2AR_CAVPO P46616 CHEMBL2605 Adenosine A2a Receptor, Guinea Pig 2
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 2
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 2
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 2
ADRB1_MOUSE P34971 CHEMBL3440 Beta-1 Adrenergic Receptor, Mouse 2
ADRB2_CAVPO Q8K4Z4 CHEMBL5414 Beta-2 Adrenergic Receptor, Guinea Pig 2
ADRB2_MESAU P04274 CHEMBL5943 Beta-2 Adrenergic Receptor, Mesau 2
ADRB2_MOUSE P18762 CHEMBL3707 Beta-2 Adrenergic Receptor, Mouse 2
ADRB3_MOUSE P25962 CHEMBL4030 Beta-3 Adrenergic Receptor, Mouse 2
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 2
CNR1_MOUSE P47746 CHEMBL3037 Cannabinoid CB1 Receptor, Mouse 2
FFAR1_HUMAN O14842 CHEMBL4422 Free Fatty Acid Receptor 1, Human 2
GBRR1_HUMAN P24046 CHEMBL3561 GABA Receptor Rho-1 Subunit, Human 2
THAS_HUMAN P24557 CHEMBL1835 Thromboxane-A Synthase, Human 2
Z100489 Z100489 CHEMBL614636 Eosinophils (Eosinophils) 2
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 2
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 2
Z50038 Z50038 CHEMBL612328 Plasmodium Yoelii Yoelii 2
Z80024 Z80024 CHEMBL614518 A9 (Fibroblast Cells) 2
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 2
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 2
Z80492 Z80492 CHEMBL614924 SK-N-SH (Neuroblastoma Cells) 2
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 2
Z81011 Z81011 CHEMBL614840 Human Cell Lines 2
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 1
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 1
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
ACM3_MOUSE Q9ERZ3 CHEMBL5105 Muscarinic Acetylcholine Receptor M3, Mouse 1
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 1
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 1
ADA1A_RABIT O02824 CHEMBL3637 Alpha-1a Adrenergic Receptor, Rabit 1
ADA1D_RABIT O02666 CHEMBL4407 Alpha-1d Adrenergic Receptor, Rabit 1
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 1
ARP19_RAT Q712U5 CHEMBL2170 Cyclic AMP Phosphoprotein, Rat 1
CAC1C_RABIT P15381 CHEMBL2830 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rabit 1
CNR1_RAT P20272 CHEMBL3571 Cannabinoid CB1 Receptor, Rat 1
CNR2_HUMAN P34972 CHEMBL253 Cannabinoid CB2 Receptor, Human 1
CNR2_RAT Q9QZN9 CHEMBL2470 Cannabinoid CB2 Receptor, Rat 1
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
GASR_RAT P30553 CHEMBL3508 Cholecystokinin B Receptor, Rat 1
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 Receptor, Guinea Pig 1
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 Receptor, Human 1
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 1
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 1
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 1
KCND3_HUMAN Q9UK17 CHEMBL1964 Voltage-gated Potassium Channel Subunit Kv4.3, Human 1
KCNQ1_CAVPO O70344 CHEMBL5135 Voltage-gated Potassium Channel Subunit Kv7.1, Guinea Pig 1
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 1
LT4R1_HUMAN Q15722 CHEMBL3911 Leukotriene B4 Receptor 1, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
MDR1_MOUSE P06795 CHEMBL3467 P-glycoprotein 1, Mouse 1
MDR3_MOUSE P21447 CHEMBL2573 P-glycoprotein 3, Mouse 1
P97706_RAT P97706 CHEMBL4957 Sodium Channel Protein Type VI Alpha Subunit, Rat 1
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 1
PDK2_HUMAN Q15119 CHEMBL3861 Pyruvate Dehydrogenase Kinase Isoform 2, Human 1
PDK3_HUMAN Q15120 CHEMBL3893 Pyruvate Dehydrogenase Kinase Isoform 3, Human 1
PDK4_HUMAN Q16654 CHEMBL4141 Pyruvate Dehydrogenase Kinase Isoform 4, Human 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
Q8CGM4_CAVPO Q8CGM4 CHEMBL5430 Mu-opioid Receptor, Guinea Pig 1
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 1
SCN5A_RAT P15389 CHEMBL3866 Sodium Channel Protein Type V Alpha Subunit, Rat 1
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1
TRPV1_HUMAN Q8NER1 CHEMBL4794 Vanilloid Receptor, Human 1
Z100201 Z100201 CHEMBL612422 Splenocytes (Spleen Cells) 1
Z102213 Z102213 CHEMBL613416 Blood 1
Z102372 Z102372 CHEMBL613672 Aorta 1
Z102380 Z102380 CHEMBL613680 Ileum 1
Z50501 Z50501 CHEMBL613109 Gallus Gallus 1
Z50589 Z50589 CHEMBL612670 Felis Catus 1
Z50740 Z50740 CHEMBL612361 Cricetinae Gen. Sp. 1
Z80051 Z80051 CHEMBL614532 C6-BU-1 1
Z80120 Z80120 CHEMBL614285 DLD-1 (Colon Adenocarcinoma Cells) 1
Z80133 Z80133 CHEMBL614294 EMT6 (Mammary Carcinoma Cells) 1
Z80164 Z80164 CHEMBL614580 HT-1080 (Fibrosarcoma Cells) 1
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 1
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 1
Z80232 Z80232 CHEMBL614128 MCF7-VP 1
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 1
Z80364 Z80364 CHEMBL614218 P388/ADR (Lymphoma Cells) 1
Z80420 Z80420 CHEMBL614632 RBL-2H3 (Basophilic Leukemia Cells) 1
Z80532 Z80532 CHEMBL614774 T-24 (Bladder Carcinoma Cells) 1
Z80558 Z80558 CHEMBL615020 U11 MG 1
Z80563 Z80563 CHEMBL615025 U-373 MG ( Glioblastoma Cells) 1
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 1
Z80711 Z80711 CHEMBL613829 NCI/ADR-RES (Breast Carcinoma Cells) 1
Z80773 Z80773 CHEMBL614456 CHRC/5 Cell Line 1
Z80774 Z80774 CHEMBL614457 CHRC5 Cell Line 1
Z80800 Z80800 CHEMBL614725 MIA PaCa-2 (Pancreatic Carcinoma Cells) 1
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 1
Z81008 Z81008 CHEMBL614788 Human Breast Cancer Cell Lines 1
Z81047 Z81047 CHEMBL614685 Human T-cell Line 1
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 1
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 1
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 1
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 1
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 1

Most Common Rings