CNR2_HUMAN - Cannabinoid CB2 Receptor, Human | ZINC Is Not Commercial - A database of commercially-available compounds

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	2,540	143	15	10
Binding ≤ 1μM	1,897	95	14	10
Functional ≤ 10μM	602	42	2	1

Reactome ID	Description	Species
REACT_14828	Class A/1 (Rhodopsin-like receptors)	Homo sapiens
REACT_19231	G alpha (i) signalling events	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
CNR1_HUMAN	P21554	CHEMBL218	Cannabinoid CB1 Receptor, Human	1694
GPR55_HUMAN	Q9Y2T6	CHEMBL1075322	G-protein Coupled Receptor 55, Human	1

G alpha (i) signalling events

Uniprot	Swissprot	Chembl	Description	Number Shared
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	1
CNR1_HUMAN	P21554	CHEMBL218	Cannabinoid CB1 Receptor, Human	1694
GPR55_HUMAN	Q9Y2T6	CHEMBL1075322	G-protein Coupled Receptor 55, Human	1
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	3
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
CNR2_MOUSE	P47936	CHEMBL5373	Cannabinoid CB2 Receptor, Mouse	293	28	11	5
CNR2_RAT	Q9QZN9	CHEMBL2470	Cannabinoid CB2 Receptor, Rat	130	21	8	3

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
CNR1_HUMAN	P21554	CHEMBL218	Cannabinoid CB1 Receptor, Human	2,791	161	19	12
CNRG_HUMAN	P18545	CHEMBL2415	Phosphodiesterase 6G, Human	33	5	5	5

Clustered By Gene (0)

Clustered By Organism (2)

Code	Description	Substances	Purchasable	Natural	In Man
CNR2-1-E	Cannabinoid CB2 Receptor (cluster #1 Of 3), Eukaryotic	2,141	115	6	6
CNR2-2-E	Cannabinoid CB2 Receptor (cluster #2 Of 3), Eukaryotic	83	15	5	0
CNR2-3-E	Cannabinoid CB2 Receptor (cluster #3 Of 3), Eukaryotic	631	46	16	10

Uniprot	Swissprot	Chembl	Description	Number Shared
CNR1_HUMAN	P21554	CHEMBL218	Cannabinoid CB1 Receptor, Human	1669
CNR1_RAT	P20272	CHEMBL3571	Cannabinoid CB1 Receptor, Rat	389
CNR2_MOUSE	P47936	CHEMBL5373	Cannabinoid CB2 Receptor, Mouse	112
CNR2_RAT	Q9QZN9	CHEMBL2470	Cannabinoid CB2 Receptor, Rat	81
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	38
CNR1_MOUSE	P47746	CHEMBL3037	Cannabinoid CB1 Receptor, Mouse	22
TSPO_RAT	P16257	CHEMBL4552	Peripheral-type Benzodiazepine Receptor, Rat	9
FAAH1_HUMAN	O00519	CHEMBL2243	Anandamide Amidohydrolase, Human	5
FAAH1_RAT	P97612	CHEMBL3229	Anandamide Amidohydrolase, Rat	5
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	3
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	3
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	2
CCKAR_HUMAN	P32238	CHEMBL1901	Cholecystokinin A Receptor, Human	2
CCKAR_MOUSE	O08786	CHEMBL2798	Cholecystokinin A Receptor, Mouse	2
DGLA_HUMAN	Q9Y4D2	CHEMBL5545	Sn1-specific Diacylglycerol Lipase Alpha, Human	2
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	2
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	2
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	1
ADCY5_RAT	Q04400	CHEMBL2880	Adenylate Cyclase Type V, Rat	1
GPR55_HUMAN	Q9Y2T6	CHEMBL1075322	G-protein Coupled Receptor 55, Human	1
NR1I2_HUMAN	O75469	CHEMBL3401	Pregnane X Receptor, Human	1
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	1
PAR1_HUMAN	P25116	CHEMBL3974	Proteinase Activated Receptor 1, Human	1
PGH2_HUMAN	P35354	CHEMBL230	Cyclooxygenase-2, Human	1
PTGDS_MOUSE	O09114	CHEMBL4334	Prostaglandin-H2 D-isomerase, Mouse	1
TRPV1_HUMAN	Q8NER1	CHEMBL4794	Vanilloid Receptor, Human	1
TRPV1_RAT	O35433	CHEMBL5102	Vanilloid Receptor, Rat	1
TSPOA_HUMAN	P30536	CHEMBL5742	Translocator Protein, Human	1
Z50512	Z50512	CHEMBL369	Cavia Porcellus	1
Z50594	Z50594	CHEMBL375	Mus Musculus	1
Z81072	Z81072	CHEMBL397	Jurkat (Acute Leukemic T-cells)	1