UCSF
Image of Pyrrole

Identity 99% 90% 80% 70% Substructure

Pyrrole

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Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
1 1 5 4 1 0 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 797 99,713 1,558 11,931 30 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 99 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 88 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 82 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADK_HUMAN P55263 CHEMBL3589 Adenosine Kinase, Human 75 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 55 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADK_HUMAN P55263 CHEMBL3589 Adenosine Kinase, Human 51 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 51 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC1_HUMAN Q13547 CHEMBL325 Histone Deacetylase 1, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 42 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 41 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 41 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 40 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 40 Annotations Catalogs SMILES SDF Mol2 Flexibase
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 39 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC1_HUMAN Q13547 CHEMBL325 Histone Deacetylase 1, Human 37 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 36 Annotations Catalogs SMILES SDF Mol2 Flexibase
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 35 Annotations Catalogs SMILES SDF Mol2 Flexibase
DGAT1_HUMAN O75907 CHEMBL6009 Diacylglycerol O-acyltransferase 1, Human 35 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 35 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 34 Annotations Catalogs SMILES SDF Mol2 Flexibase
CNR1_RAT P20272 CHEMBL3571 Cannabinoid CB1 Receptor, Rat 34 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 34 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 34 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_HUMAN P35610 CHEMBL2782 Acyl Coenzyme A:cholesterol Acyltransferase 1, Human 33 Annotations Catalogs SMILES SDF Mol2 Flexibase
DGAT1_HUMAN O75907 CHEMBL6009 Diacylglycerol O-acyltransferase 1, Human 32 Annotations Catalogs SMILES SDF Mol2 Flexibase
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 32 Annotations Catalogs SMILES SDF Mol2 Flexibase
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 32 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNPH_BOVIN P55859 CHEMBL2935 Purine Nucleoside Phosphorylase, Bovin 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNPH_BOVIN P55859 CHEMBL2935 Purine Nucleoside Phosphorylase, Bovin 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8MMZ8_EIMTE Q8MMZ8 CHEMBL5036 CGMP-dependent Protein Kinase, Eimte 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8MMZ8_EIMTE Q8MMZ8 CHEMBL5036 CGMP-dependent Protein Kinase, Eimte 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 30 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 30 Annotations Catalogs SMILES SDF Mol2 Flexibase
CNR1_RAT P20272 CHEMBL3571 Cannabinoid CB1 Receptor, Rat 30 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 30 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 29 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 28 Annotations Catalogs SMILES SDF Mol2 Flexibase
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 28 Annotations Catalogs SMILES SDF Mol2 Flexibase
ICMT_HUMAN O60725 CHEMBL4699 Isoprenylcysteine Carboxyl Methyltransferase, Human 27 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_BOVIN P23795 CHEMBL4768 Acetylcholinesterase, Bovin 26 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_BOVIN P23795 CHEMBL4768 Acetylcholinesterase, Bovin 26 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 26 Annotations Catalogs SMILES SDF Mol2 Flexibase
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 25 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 25 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 25 Annotations Catalogs SMILES SDF Mol2 Flexibase
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA1_HUMAN P42261 CHEMBL2009 Glutamate Receptor Ionotropic, AMPA 1, Human 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate Receptor Ionotropic, AMPA 2, Human 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA3_HUMAN P42263 CHEMBL3595 Glutamate Receptor Ionotropic, AMPA 3, Human 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA4_HUMAN P48058 CHEMBL3190 Glutamate Receptor Ionotropic, AMPA 4, Human 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 23 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 23 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 23 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 23 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_HUMAN P35610 CHEMBL2782 Acyl Coenzyme A:cholesterol Acyltransferase 1, Human 23 Annotations Catalogs SMILES SDF Mol2 Flexibase
IMDH2_HUMAN P12268 CHEMBL2002 Inosine-5'-monophosphate Dehydrogenase 2, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
PTAFR_HUMAN P25105 CHEMBL250 Platelet Activating Factor Receptor, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA1_HUMAN P42261 CHEMBL2009 Glutamate Receptor Ionotropic, AMPA 1, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate Receptor Ionotropic, AMPA 2, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA3_HUMAN P42263 CHEMBL3595 Glutamate Receptor Ionotropic, AMPA 3, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA4_HUMAN P48058 CHEMBL3190 Glutamate Receptor Ionotropic, AMPA 4, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC6_HUMAN Q9UBN7 CHEMBL1865 Histone Deacetylase 6, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARD_HUMAN Q03181 CHEMBL3979 Peroxisome Proliferator-activated Receptor Delta, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC2_HUMAN Q92769 CHEMBL1937 Histone Deacetylase 2, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC3_HUMAN O15379 CHEMBL1829 Histone Deacetylase 3, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC4_HUMAN P56524 CHEMBL3524 Histone Deacetylase 4, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC5_HUMAN Q9UQL6 CHEMBL2563 Histone Deacetylase 5, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC7_HUMAN Q8WUI4 CHEMBL2716 Histone Deacetylase 7, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC8_HUMAN Q9BY41 CHEMBL3192 Histone Deacetylase 8, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARA_HUMAN Q07869 CHEMBL239 Peroxisome Proliferator-activated Receptor Alpha, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 17 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDA10_HUMAN Q969S8 CHEMBL5103 Histone Deacetylase 10, Human 17 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDA11_HUMAN Q96DB2 CHEMBL3310 Histone Deacetylase 11, Human 17 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC6_HUMAN Q9UBN7 CHEMBL1865 Histone Deacetylase 6, Human 17 Annotations Catalogs SMILES SDF Mol2 Flexibase