UCSF

Serine/threonine-protein Kinase AKT, Human (1,046 Compounds)

Swissprot:
AKT1_HUMAN
Stitch:
AKT1_HUMAN
UniProt:
P31749
ChEMBL:
CHEMBL4282
Reactome:
REACT_549
REACT_12564
REACT_12442
REACT_13655
REACT_24915
REACT_19358
REACT_147727
REACT_19405
REACT_200731
REACT_115662
REACT_12477
REACT_19290
REACT_1695
REACT_15523
REACT_25042
REACT_12447
REACT_75829
REACT_111176
REACT_147867
REACT_228016
PDB:
1H10 (DOCK)
1UNP (DOCK)
1UNQ (DOCK)
1UNR (DOCK)
2UVM (DOCK)
2UZR (DOCK)
2UZS (DOCK)
3CQU (DOCK)
3CQW (DOCK)
3MV5 (DOCK)
3MVH (DOCK)
3O96 (DOCK)
3OCB (DOCK)
3OW4 (DOCK)
3QKK (DOCK)
3QKL (DOCK)
3QKM (DOCK)
AKT1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1,046 20 3 13
Binding ≤ 1μM 877 11 3 12
Functional ≤ 10μM 14 1 1 4

Reactome Network (20)

Reactome ID Description Species
REACT_549 Activation of BAD and translocation to mitochondria Homo sapiens
REACT_12564 AKT phosphorylates targets in the cytosol Homo sapiens
REACT_12442 AKT phosphorylates targets in the nucleus Homo sapiens
REACT_13655 AKT-mediated inactivation of FOXO1A Homo sapiens
REACT_24915 Butyrate Response Factor 1 (BRF1) destabilizes mRNA Homo sapiens
REACT_19358 CD28 dependent PI3K/Akt signaling Homo sapiens
REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Homo sapiens
REACT_19405 CTLA4 inhibitory signaling Homo sapiens
REACT_200731 deactivation of the beta-catenin transactivating complex Homo sapiens
REACT_115662 Downregulation of ERBB2:ERBB3 signaling Homo sapiens
REACT_12477 eNOS activation Homo sapiens
REACT_19290 G beta:gamma signalling through PI3Kgamma Homo sapiens
REACT_1695 GPVI-mediated activation cascade Homo sapiens
REACT_15523 Integrin alphaIIb beta3 signaling Homo sapiens
REACT_25042 KSRP destabilizes mRNA Homo sapiens
REACT_12447 Negative regulation of the PI3K/AKT network Homo sapiens
REACT_75829 PIP3 activates AKT signaling Homo sapiens
REACT_111176 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation Homo sapiens
REACT_147867 Translocation of GLUT4 to the plasma membrane Homo sapiens
REACT_228016 VEGFR2 mediated vascular permeability Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120

AKT phosphorylates targets in the cytosol

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120
AKTS1_HUMAN Q96B36 CHEMBL1255161 Proline-rich AKT1 Substrate 1, Human 3
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 3
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 36
IKKA_HUMAN O15111 CHEMBL3476 Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, Human 5

AKT phosphorylates targets in the nucleus

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120
KS6B2_HUMAN Q9UBS0 CHEMBL3111 Ribosomal Protein S6 Kinase 2, Human 1

AKT-mediated inactivation of FOXO1A

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120

Butyrate Response Factor 1 (BRF1) destabilizes mRNA

Uniprot Swissprot Chembl Description Number Shared
MAPK2_HUMAN P49137 CHEMBL2208 MAP Kinase-activated Protein Kinase 2, Human 7

CD28 dependent PI3K/Akt signaling

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 2
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 3
M3K14_HUMAN Q99558 CHEMBL5888 Mitogen-activated Protein Kinase Kinase Kinase 14, Human 1
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 41
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 2
P85B_HUMAN O00459 CHEMBL4437 PI3-kinase P85-beta Subunit, Human 2
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 25
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 43

Constitutive PI3K/AKT Signaling in Cancer

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120
AKTS1_HUMAN Q96B36 CHEMBL1255161 Proline-rich AKT1 Substrate 1, Human 3
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 8
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 1
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 2
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 3
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 36
IKKA_HUMAN O15111 CHEMBL3476 Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, Human 5
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 9
KS6B2_HUMAN Q9UBS0 CHEMBL3111 Ribosomal Protein S6 Kinase 2, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 3
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 41
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 2
P85B_HUMAN O00459 CHEMBL4437 PI3-kinase P85-beta Subunit, Human 2
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 25
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 2
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 2
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 43
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 7
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 7

CTLA4 inhibitory signaling

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 2
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 3
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 2
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 25
YES_HUMAN P07947 CHEMBL2073 Tyrosine-protein Kinase YES, Human 1

deactivation of the beta-catenin transactivating complex

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265

Downregulation of ERBB2:ERBB3 signaling

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 1

G beta:gamma signalling through PI3Kgamma

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 25
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 7

GPVI-mediated activation cascade

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 2
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 1
KSYK_HUMAN P43405 CHEMBL2599 Tyrosine-protein Kinase SYK, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 3
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 2
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 2
P85B_HUMAN O00459 CHEMBL4437 PI3-kinase P85-beta Subunit, Human 2
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 25
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 43
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 7
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 7

Integrin alphaIIb beta3 signaling

Uniprot Swissprot Chembl Description Number Shared
CSK_HUMAN P41240 CHEMBL2634 Tyrosine-protein Kinase CSK, Human 1
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 2
KSYK_HUMAN P43405 CHEMBL2599 Tyrosine-protein Kinase SYK, Human 1
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 25

KSRP destabilizes mRNA

Uniprot Swissprot Chembl Description Number Shared
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1

Negative regulation of the PI3K/AKT network

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120

PIP3 activates AKT signaling

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 8
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 1
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 2
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 9
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 3
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 41
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 2
P85B_HUMAN O00459 CHEMBL4437 PI3-kinase P85-beta Subunit, Human 2
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 25
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 2
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 2
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 43
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 7
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 7

Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation

Uniprot Swissprot Chembl Description Number Shared
KGP2_HUMAN Q13237 CHEMBL2896 CGMP-dependent Protein Kinase 2, Human 2

Translocation of GLUT4 to the plasma membrane

Uniprot Swissprot Chembl Description Number Shared
AAKB1_HUMAN Q9Y478 CHEMBL3847 AMP-activated Protein Kinase, Beta-1 Subunit, Human 1
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 1
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265

VEGFR2 mediated vascular permeability

Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 41
PAK1_HUMAN Q13153 CHEMBL4600 Serine/threonine-protein Kinase PAK 1, Human 3
PAK2_HUMAN Q13177 CHEMBL4487 Serine/threonine-protein Kinase PAK 2, Human 1
PAK3_HUMAN O75914 CHEMBL2999 Serine/threonine-protein Kinase PAK 3, Human 1
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 25
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
AKT1_MOUSE P31750 CHEMBL5859 RAC-alpha Serine/threonine-protein Kinase, Mouse 16 2 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 390 13 2 14
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 152 9 1 7
AKTS1_HUMAN Q96B36 CHEMBL1255161 Proline-rich AKT1 Substrate 1, Human 3 0 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
AKT1-1-E RAC-alpha Serine/threonine-protein Kinase (cluster #1 Of 3), Eukaryotic 32 1 1 1
AKT1-2-E RAC-alpha Serine/threonine-protein Kinase (cluster #2 Of 3), Eukaryotic 1,037 20 2 12
AKT1-3-E RAC-alpha Serine/threonine-protein Kinase (cluster #3 Of 3), Eukaryotic 1 0 0 0
Uniprot Swissprot Chembl Description Number Shared
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 265
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 120
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 46
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 43
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 42
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 41
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 36
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 34
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 34
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 34
KS6B1_HUMAN P23443 CHEMBL4501 Ribosomal Protein S6 Kinase 1, Human 25
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 25
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 24
KS6A1_HUMAN Q15418 CHEMBL2553 Ribosomal Protein S6 Kinase Alpha 1, Human 20
KS6A5_HUMAN O75582 CHEMBL4237 Ribosomal Protein S6 Kinase Alpha 5, Human 17
CHK1_HUMAN O14757 CHEMBL4630 Serine/threonine-protein Kinase Chk1, Human 12
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 12
KAP2_BOVIN P00515 CHEMBL3654 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Bovin 10
KAPCA_BOVIN P00517 CHEMBL2654 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Bovin 10
KAPCB_BOVIN P05131 CHEMBL3279 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Bovin 10
MK01_HUMAN P28482 CHEMBL4040 MAP Kinase ERK2, Human 10
KAP3_BOVIN P31322 CHEMBL3280 CAMP-dependent Protein Kinase Type II-beta Regulatory Subunit, Bovin 9
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 9
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 9
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 9
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 9
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 8
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 8
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 8
Z80800 Z80800 CHEMBL614725 MIA PaCa-2 (Pancreatic Carcinoma Cells) 8
IKKB_HUMAN O14920 CHEMBL1991 Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human 7
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 7
MAPK2_HUMAN P49137 CHEMBL2208 MAP Kinase-activated Protein Kinase 2, Human 7
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 7
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 7
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 7
Q95J97_RABIT Q95J97 CHEMBL4885 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rabit 7
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 6
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 6
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 6
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 6
IKKA_HUMAN O15111 CHEMBL3476 Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit, Human 5
Z100089 Z100089 CHEMBL614948 F5.12 (IL3-dependent Haematopoietic Cells) 5
CHK2_HUMAN O96017 CHEMBL2527 Serine/threonine-protein Kinase Chk2, Human 4
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 4
MARK2_HUMAN Q7KZI7 CHEMBL3831 MAP/microtubule Affinity-regulating Kinase 2, Human 4
PLK3_HUMAN Q9H4B4 CHEMBL4897 Serine/threonine-protein Kinase PLK3, Human 4
SGK1_HUMAN O00141 CHEMBL2343 Serine/threonine-protein Kinase Sgk1, Human 4
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 4
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 3
AKTS1_HUMAN Q96B36 CHEMBL1255161 Proline-rich AKT1 Substrate 1, Human 3
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 3
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 3
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 3
CSK22_HUMAN P19784 CHEMBL4070 Casein Kinase II Alpha (prime), Human 3
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 3
DAPK3_HUMAN O43293 CHEMBL2468 Death-associated Protein Kinase 3, Human 3
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 3
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 3
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 3
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 3
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 3
KCC2A_HUMAN Q9UQM7 CHEMBL4147 CaM Kinase II Alpha, Human 3
KGP1_HUMAN Q13976 CHEMBL4273 CGMP-dependent Protein Kinase 1 Beta, Human 3
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 3
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 3
KS6A3_HUMAN P51812 CHEMBL2345 Ribosomal Protein S6 Kinase Alpha 3, Human 3
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 3
MARK3_HUMAN P27448 CHEMBL5600 Serine/threonine-protein Kinase C-TAK1, Human 3
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 3
MK09_HUMAN P45984 CHEMBL4179 C-Jun N-terminal Kinase 2, Human 3
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 3
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 3
PAK1_HUMAN Q13153 CHEMBL4600 Serine/threonine-protein Kinase PAK 1, Human 3
PAK4_HUMAN O96013 CHEMBL4482 Serine/threonine-protein Kinase PAK 4, Human 3
SRPK1_HUMAN Q96SB4 CHEMBL4375 Serine/threonine-protein Kinase SRPK1, Human 3
BLK_HUMAN P51451 CHEMBL2250 Tyrosine-protein Kinase BLK, Human 2
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 2
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 2
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 2
CSF1R_HUMAN P07333 CHEMBL1844 Macrophage Colony Stimulating Factor Receptor, Human 2
EPHA2_HUMAN P29317 CHEMBL2068 Ephrin Type-A Receptor 2, Human 2
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin Type-A Receptor 3, Human 2
EPHB4_HUMAN P54760 CHEMBL5147 Ephrin Type-B Receptor 4, Human 2
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 2
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 2
HCK_HUMAN P08631 CHEMBL3234 Tyrosine-protein Kinase HCK, Human 2
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 2
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 2
KCC2B_HUMAN Q13554 CHEMBL4121 CaM Kinase II Beta, Human 2
KCC2D_HUMAN Q13557 CHEMBL2801 CaM Kinase II Delta, Human 2
KCC2G_HUMAN Q13555 CHEMBL3829 CaM Kinase II Gamma, Human 2
KGP2_HUMAN Q13237 CHEMBL2896 CGMP-dependent Protein Kinase 2, Human 2
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 2
KPCD2_HUMAN Q9BZL6 CHEMBL4900 Serine/threonine-protein Kinase D2, Human 2
KS6A4_HUMAN O75676 CHEMBL3125 Ribosomal Protein S6 Kinase Alpha 4, Human 2
LIMK1_HUMAN P53667 CHEMBL3836 LIM Domain Kinase 1, Human 2
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 2
MK03_HUMAN P27361 CHEMBL3385 MAP Kinase ERK1, Human 2
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 2
MYLK_HUMAN Q15746 CHEMBL2428 Myosin Light Chain Kinase, Smooth Muscle, Human 2
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 2
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 2
P85B_HUMAN O00459 CHEMBL4437 PI3-kinase P85-beta Subunit, Human 2
PAK6_HUMAN Q9NQU5 CHEMBL4311 Serine/threonine-protein Kinase PAK6, Human 2
PAK7_HUMAN Q9P286 CHEMBL4524 Serine/threonine-protein Kinase PAK7, Human 2
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 2
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 2
PK3CA_BOVIN P32871 CHEMBL2498 PI3-kinase P110-alpha Subunit, Bovin 2
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 2
PRKDC_HUMAN P78527 CHEMBL3142 DNA-dependent Protein Kinase, Human 2
PRKX_HUMAN P51817 CHEMBL5818 Serine/threonine-protein Kinase PRKX, Human 2
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 2
RET_HUMAN P07949 CHEMBL2041 Tyrosine-protein Kinase Receptor RET, Human 2
ROCK1_RAT Q63644 CHEMBL5509 Rho-associated Protein Kinase 1, Rat 2
ST17B_HUMAN O94768 CHEMBL3980 Serine/threonine-protein Kinase 17B, Human 2
STK3_HUMAN Q13188 CHEMBL4708 Serine/threonine-protein Kinase MST2, Human 2
TYK2_HUMAN P29597 CHEMBL3553 Tyrosine-protein Kinase TYK2, Human 2
UFO_HUMAN P30530 CHEMBL4895 Tyrosine-protein Kinase Receptor UFO, Human 2
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 2
VGFR1_MOUSE P35969 CHEMBL3516 Vascular Endothelial Growth Factor Receptor 1, Mouse 2
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 2
AAK1_HUMAN Q2M2I8 CHEMBL3830 Adaptor-associated Kinase, Human 1
AAKB1_HUMAN Q9Y478 CHEMBL3847 AMP-activated Protein Kinase, Beta-1 Subunit, Human 1
AAPK1_HUMAN Q13131 CHEMBL4045 AMP-activated Protein Kinase, Alpha-1 Subunit, Human 1
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 1
AAPK2_RAT Q09137 CHEMBL4637 AMP-activated Protein Kinase, Alpha-2 Subunit, Rat 1
ABL2_HUMAN P42684 CHEMBL4014 Tyrosine-protein Kinase ABL2, Human 1
ACH10_RAT Q9JLB5 CHEMBL3461 Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Rat 1
ACHA2_RAT P12389 CHEMBL2584 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat 1
ACHA3_RAT P04757 CHEMBL3818 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat 1
ACHA4_RAT P09483 CHEMBL307 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat 1
ACHA5_RAT P20420 CHEMBL4960 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Rat 1
ACHA6_RAT P43143 CHEMBL4747 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Rat 1
ACHA7_RAT Q05941 CHEMBL4980 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat 1
ACHA9_RAT P43144 CHEMBL2585 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Rat 1
ACHA_RAT P25108 CHEMBL3599 Acetylcholine Receptor Protein Alpha Chain, Rat 1
ACHB2_RAT P12390 CHEMBL3001 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat 1
ACHB3_RAT P12391 CHEMBL4568 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat 1
ACHB4_RAT P12392 CHEMBL2658 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat 1
ACHB_RAT P25109 CHEMBL2666 Acetylcholine Receptor Protein Beta Chain, Rat 1
ACK1_HUMAN Q07912 CHEMBL4599 Tyrosine Kinase Non-receptor Protein 2, Human 1
ACV1B_HUMAN P36896 CHEMBL5310 Activin Receptor Type-1B, Human 1
ACVR1_HUMAN Q04771 CHEMBL5903 Activin Receptor Type-1, Human 1
AKT1_MOUSE P31750 CHEMBL5859 RAC-alpha Serine/threonine-protein Kinase, Mouse 1
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 1
ANKK1_HUMAN Q8NFD2 CHEMBL5547 Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human 1
AURKC_HUMAN Q9UQB9 CHEMBL3935 Serine/threonine-protein Kinase Aurora-C, Human 1
AVR2B_HUMAN Q13705 CHEMBL5466 Activin Receptor Type-2B, Human 1
BLK_MOUSE P16277 CHEMBL3343 Tyrosine-protein Kinase BLK, Mouse 1
BMP2K_HUMAN Q9NSY1 CHEMBL4522 BMP-2-inducible Protein Kinase, Human 1
BMR1A_HUMAN P36894 CHEMBL5275 Bone Morphogenetic Protein Receptor Type-1A, Human 1
BMX_HUMAN P51813 CHEMBL3834 Tyrosine-protein Kinase BMX, Human 1
BRSK1_HUMAN Q8TDC3 CHEMBL5650 BR Serine/threonine-protein Kinase 1, Human 1
BRSK2_HUMAN Q8IWQ3 CHEMBL4574 BR Serine/threonine-protein Kinase 2, Human 1
BTK_HUMAN Q06187 CHEMBL5251 Tyrosine-protein Kinase BTK, Human 1
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1
CDK14_HUMAN O94921 CHEMBL6162 Serine/threonine-protein Kinase PFTAIRE-1, Human 1
CDK16_HUMAN Q00536 CHEMBL4597 Serine/threonine-protein Kinase PCTAIRE-1, Human 1
CDK17_HUMAN Q00537 CHEMBL5790 Serine/threonine-protein Kinase PCTAIRE-2, Human 1
CDK18_HUMAN Q07002 CHEMBL5316 Serine/threonine-protein Kinase PCTAIRE-3, Human 1
CDK19_HUMAN Q9BWU1 CHEMBL6002 Cell Division Cycle 2-like Protein Kinase 6, Human 1
CDK1_MOUSE P11440 CHEMBL4084 Cyclin-dependent Kinase 1, Mouse 1
CDK3_HUMAN Q00526 CHEMBL4442 Cyclin-dependent Kinase 3, Human 1
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 1
CDK6_HUMAN Q00534 CHEMBL2508 Cyclin-dependent Kinase 6, Human 1
CDK7_HUMAN P50613 CHEMBL3055 Cyclin-dependent Kinase 7, Human 1
CDK8_HUMAN P49336 CHEMBL5719 Cell Division Protein Kinase 8, Human 1
CDK9_HUMAN P50750 CHEMBL3116 Cyclin-dependent Kinase 9, Human 1
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 1
CLK2_HUMAN P49760 CHEMBL4225 Dual Specificity Protein Kinase CLK2, Human 1
CLK3_HUMAN P49761 CHEMBL4226 Dual Specificity Protein Kinase CLK3, Human 1
CLK4_HUMAN Q9HAZ1 CHEMBL4203 Dual Specificity Protein Kinase CLK4, Human 1
CSK21_RAT P19139 CHEMBL2661 Casein Kinase II Alpha, Rat 1
CSK2B_RAT P67874 CHEMBL2463 Casein Kinase II Beta, Rat 1
CSK_HUMAN P41240 CHEMBL2634 Tyrosine-protein Kinase CSK, Human 1
CTRO_HUMAN O14578 CHEMBL5579 Citron Rho-interacting Kinase, Human 1
DAPK1_HUMAN P53355 CHEMBL2558 Death-associated Protein Kinase 1, Human 1
DAPK2_HUMAN Q9UIK4 CHEMBL3123 Death-associated Protein Kinase 2, Human 1
DCLK1_HUMAN O15075 CHEMBL5683 Serine/threonine-protein Kinase DCLK1, Human 1
DCLK2_HUMAN Q8N568 CHEMBL5519 Serine/threonine-protein Kinase DCLK2, Human 1
DCLK3_HUMAN Q9C098 CHEMBL6123 Serine/threonine-protein Kinase DCLK3, Human 1
DDR1_HUMAN Q08345 CHEMBL5319 Epithelial Discoidin Domain-containing Receptor 1, Human 1
DDR2_HUMAN Q16832 CHEMBL5122 Discoidin Domain-containing Receptor 2, Human 1
DMPK_HUMAN Q09013 CHEMBL5320 Myotonin-protein Kinase, Human 1
DUS3_HUMAN P51452 CHEMBL2635 Dual Specificity Protein Phosphatase 3, Human 1
DYR1B_HUMAN Q9Y463 CHEMBL5543 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human 1
E2AK2_HUMAN P19525 CHEMBL5785 Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human 1
E2AK4_HUMAN Q9P2K8 CHEMBL5358 Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human 1
EPHA1_HUMAN P21709 CHEMBL5810 Ephrin Type-A Receptor 1, Human 1
EPHA4_HUMAN P54764 CHEMBL3988 Ephrin Type-A Receptor 4, Human 1
EPHA5_HUMAN P54756 CHEMBL3987 Ephrin Type-A Receptor 5, Human 1
EPHA6_HUMAN Q9UF33 CHEMBL4526 Ephrin Type-A Receptor 6, Human 1
EPHA7_HUMAN Q15375 CHEMBL4602 Ephrin Type-A Receptor 7, Human 1
EPHA8_HUMAN P29322 CHEMBL4134 Ephrin Type-A Receptor 8, Human 1
EPHB1_HUMAN P54762 CHEMBL5072 Ephrin Type-B Receptor 1, Human 1
EPHB2_HUMAN P29323 CHEMBL3290 Ephrin Type-B Receptor 2, Human 1
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 1
ERBB4_HUMAN Q15303 CHEMBL3009 Receptor Protein-tyrosine Kinase ErbB-4, Human 1
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 1
FER_HUMAN P16591 CHEMBL3982 Tyrosine-protein Kinase FER, Human 1
FES_HUMAN P07332 CHEMBL5455 Tyrosine-protein Kinase FES, Human 1
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 1
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 1
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 1
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 1
FGR_HUMAN P09769 CHEMBL4454 Tyrosine-protein Kinase FGR, Human 1
FRK_HUMAN P42685 CHEMBL4223 Tyrosine-protein Kinase FRK, Human 1
GAK_HUMAN O14976 CHEMBL4355 Serine/threonine-protein Kinase GAK, Human 1
HIPK1_HUMAN Q86Z02 CHEMBL5427 Homeodomain-interacting Protein Kinase 1, Human 1
IKKE_HUMAN Q14164 CHEMBL3529 Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human 1
INSRR_HUMAN P14616 CHEMBL5483 Insulin Receptor-related Protein, Human 1
INSR_MOUSE P15208 CHEMBL3187 Insulin Receptor, Mouse 1
IRAK1_HUMAN P51617 CHEMBL3357 Interleukin-1 Receptor-associated Kinase 1, Human 1
IRAK3_HUMAN Q9Y616 CHEMBL5081 Interleukin-1 Receptor-associated Kinase 3, Human 1
IRAK4_HUMAN Q9NWZ3 CHEMBL3778 Interleukin-1 Receptor-associated Kinase 4, Human 1
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 1
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 1
KAPCA_MOUSE P05132 CHEMBL4991 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Mouse 1
KAPCA_RAT P27791 CHEMBL3390 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rat 1
KAPCB_MOUSE P68181 CHEMBL2481 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Mouse 1
KC1AL_HUMAN Q8N752 CHEMBL5520 Casein Kinase I Isoform Alpha-like, Human 1
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 1
KC1A_MOUSE Q8BK63 CHEMBL5148 Casein Kinase I Alpha, Mouse 1
KC1D_MOUSE Q9DC28 CHEMBL5175 Casein Kinase I Delta, Mouse 1
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 1
KC1E_MOUSE Q9JMK2 CHEMBL5140 Casein Kinase I Epsilon, Mouse 1
KC1G1_HUMAN Q9HCP0 CHEMBL2426 Casein Kinase I Gamma 1, Human 1
KC1G1_MOUSE Q8BTH8 CHEMBL4455 Casein Kinase I Gamma 1, Mouse 1
KC1G2_HUMAN P78368 CHEMBL2543 Casein Kinase I Gamma 2, Human 1
KCC1A_HUMAN Q14012 CHEMBL2493 CaM Kinase I Alpha, Human 1
KCC1D_HUMAN Q8IU85 CHEMBL5073 CaM Kinase I Delta, Human 1
KCC1G_HUMAN Q96NX5 CHEMBL5258 CaM Kinase I Gamma, Human 1
KCC2A_MOUSE P11798 CHEMBL3347 CaM Kinase II Alpha, Mouse 1
KCC2A_RAT P11275 CHEMBL2359 CaM Kinase II Alpha, Rat 1
KCC2B_MOUSE P28652 CHEMBL4735 CaM Kinase II Beta, Mouse 1
KCC2G_MOUSE Q923T9 CHEMBL4456 CaM Kinase II Gamma, Mouse 1
KCC4_HUMAN Q16566 CHEMBL2494 CaM Kinase IV, Human 1
KGP1_BOVIN P00516 CHEMBL3183 CGMP-dependent Protein Kinase 1 Alpha, Bovin 1
KKCC1_HUMAN Q8N5S9 CHEMBL5256 CaM-kinase Kinase Alpha, Human 1
KKCC2_HUMAN Q96RR4 CHEMBL5284 CaM-kinase Kinase Beta, Human 1
KPB1_HUMAN P46020 CHEMBL2905 Phosphorylase Kinase Alpha M Subunit, Human 1
KPB2_HUMAN P46019 CHEMBL2906 Phosphorylase Kinase Alpha L Subunit, Human 1
KPBB_HUMAN Q93100 CHEMBL3844 Phosphorylase Kinase Beta Subunit, Human 1
KPCA_RAT P05696 CHEMBL2855 Protein Kinase C Alpha, Rat 1
KPCB_RAT P68403 CHEMBL3020 Protein Kinase C Beta, Rat 1
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 1
KPCD3_HUMAN O94806 CHEMBL2595 Protein Kinase C Nu, Human 1
KPCD_RAT P09215 CHEMBL3633 Protein Kinase C Delta, Rat 1
KPCE_RAT P09216 CHEMBL3424 Protein Kinase C Epsilon, Rat 1
KPCG_RAT P63319 CHEMBL3604 Protein Kinase C Gamma, Rat 1
KPCI_HUMAN P41743 CHEMBL2598 Protein Kinase C Iota, Human 1
KPCL_RAT Q64617 CHEMBL3990 Protein Kinase C Eta, Rat 1
KPCT_RAT Q9WTQ0 CHEMBL4563 Protein Kinase C Theta, Rat 1
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 1
KPCZ_RAT P09217 CHEMBL5379 Protein Kinase C Zeta, Rat 1
KS6A2_HUMAN Q15349 CHEMBL3906 Ribosomal Protein S6 Kinase Alpha 2, Human 1
KS6A6_HUMAN Q9UK32 CHEMBL4924 Ribosomal Protein S6 Kinase Alpha 6, Human 1
KS6B2_HUMAN Q9UBS0 CHEMBL3111 Ribosomal Protein S6 Kinase 2, Human 1
KSYK_HUMAN P43405 CHEMBL2599 Tyrosine-protein Kinase SYK, Human 1
LATS1_HUMAN O95835 CHEMBL6167 Serine/threonine-protein Kinase LATS1, Human 1
LATS2_HUMAN Q9NRM7 CHEMBL5907 Serine/threonine-protein Kinase LATS2, Human 1
LIMK2_HUMAN P53671 CHEMBL5932 LIM Domain Kinase 2, Human 1
LTK_HUMAN P29376 CHEMBL5627 Leukocyte Tyrosine Kinase Receptor, Human 1
M3K10_HUMAN Q02779 CHEMBL2873 Mitogen-activated Protein Kinase Kinase Kinase 10, Human 1
M3K11_HUMAN Q16584 CHEMBL2708 Mitogen-activated Protein Kinase Kinase Kinase 11, Human 1
M3K14_HUMAN Q99558 CHEMBL5888 Mitogen-activated Protein Kinase Kinase Kinase 14, Human 1
M3K4_HUMAN Q9Y6R4 CHEMBL4853 Mitogen-activated Protein Kinase Kinase Kinase 4, Human 1
M3K5_HUMAN Q99683 CHEMBL5285 Mitogen-activated Protein Kinase Kinase Kinase 5, Human 1
M3K7_HUMAN O43318 CHEMBL5776 Mitogen-activated Protein Kinase Kinase Kinase 7, Human 1
M3K9_HUMAN P80192 CHEMBL2872 Mitogen-activated Protein Kinase Kinase Kinase 9, Human 1
M4K1_HUMAN Q92918 CHEMBL5749 Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human 1
M4K2_HUMAN Q12851 CHEMBL5330 Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, Human 1
M4K3_HUMAN Q8IVH8 CHEMBL5432 Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human 1
M4K4_HUMAN O95819 CHEMBL6166 Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human 1
M4K5_HUMAN Q9Y4K4 CHEMBL4852 Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human 1
MAPK3_HUMAN Q16644 CHEMBL4670 MAP Kinase-activated Protein Kinase 3, Human 1
MARK1_HUMAN Q9P0L2 CHEMBL5940 Serine/threonine-protein Kinase MARK1, Human 1
MARK4_HUMAN Q96L34 CHEMBL5754 MAP/microtubule Affinity-regulating Kinase 4, Human 1
MELK_HUMAN Q14680 CHEMBL4578 Maternal Embryonic Leucine Zipper Kinase, Human 1
MERTK_HUMAN Q12866 CHEMBL5331 Proto-oncogene Tyrosine-protein Kinase MER, Human 1
MINK1_HUMAN Q8N4C8 CHEMBL5518 Misshapen-like Kinase 1, Human 1
MK07_HUMAN Q13164 CHEMBL5332 Mitogen-activated Protein Kinase 7, Human 1
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 1
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 1
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1
MK15_HUMAN Q8TD08 CHEMBL5198 Mitogen-activated Protein Kinase 15, Human 1
MKNK1_HUMAN Q9BUB5 CHEMBL4718 MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human 1
MKNK2_HUMAN Q9HBH9 CHEMBL4204 MAP Kinase Signal-integrating Kinase 2, Human 1
MLTK_HUMAN Q9NYL2 CHEMBL3886 Mixed Lineage Kinase 7, Human 1
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 1
MP2K2_HUMAN P36507 CHEMBL2964 Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human 1
MP2K3_HUMAN P46734 CHEMBL2109 Dual Specificity Mitogen-activated Protein Kinase Kinase 3, Human 1
MP2K4_HUMAN P45985 CHEMBL2897 Dual Specificity Mitogen-activated Protein Kinase Kinase 4, Human 1
MP2K6_HUMAN P52564 CHEMBL2171 Dual Specificity Mitogen-activated Protein Kinase Kinase 6, Human 1
MRCKB_HUMAN Q9Y5S2 CHEMBL5052 Serine/threonine-protein Kinase MRCK Beta, Human 1
MRCKG_HUMAN Q6DT37 CHEMBL5615 Serine/threonine-protein Kinase MRCK Gamma, Human 1
MST4_HUMAN Q9P289 CHEMBL5941 Serine/threonine-protein Kinase MST4, Human 1
MUSK_HUMAN O15146 CHEMBL5684 Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human 1
MYLK2_HUMAN Q9H1R3 CHEMBL2777 Myosin Light Chain Kinase 2, Human 1
MYLK4_HUMAN Q86YV6 CHEMBL5426 Myosin Light Chain Kinase Family Member 4, Human 1
MYLK_CHICK P11799 CHEMBL3062 Myosin Light Chain Kinase, Smooth Muscle, Chick 1
MYO3A_HUMAN Q8NEV4 CHEMBL5546 Myosin IIIA, Human 1
MYO3B_HUMAN Q8WXR4 CHEMBL5654 Myosin-IIIB, Human 1
NEK1_HUMAN Q96PY6 CHEMBL5855 Serine/threonine-protein Kinase Nek1, Human 1
NEK2_HUMAN P51955 CHEMBL3835 Serine/threonine-protein Kinase NEK2, Human 1
NEK5_HUMAN Q6P3R8 CHEMBL5044 Serine/threonine-protein Kinase Nek5, Human 1
NEK7_HUMAN Q8TDX7 CHEMBL4849 Serine/threonine-protein Kinase NEK7, Human 1
NEK9_HUMAN Q8TD19 CHEMBL5257 Serine/threonine-protein Kinase NEK9, Human 1
NLK_HUMAN Q9UBE8 CHEMBL5364 Serine/threonine Protein Kinase NLK, Human 1
NTRK2_HUMAN Q16620 CHEMBL4898 Neurotrophic Tyrosine Kinase Receptor Type 2, Human 1
NTRK3_HUMAN Q16288 CHEMBL5608 NT-3 Growth Factor Receptor, Human 1
NUAK1_HUMAN O60285 CHEMBL5784 NUAK Family SNF1-like Kinase 1, Human 1
NUAK2_HUMAN Q9H093 CHEMBL5698 NUAK Family SNF1-like Kinase 2, Human 1
P3C2B_HUMAN O00750 CHEMBL5554 Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Beta Polypeptide, Human 1
P90584_PLAFA P90584 CHEMBL4090 Protein Kinase Pfmrk, Plafa 1
PAK2_HUMAN Q13177 CHEMBL4487 Serine/threonine-protein Kinase PAK 2, Human 1
PAK3_HUMAN O75914 CHEMBL2999 Serine/threonine-protein Kinase PAK 3, Human 1
PGFRA_MOUSE P26618 CHEMBL3466 Platelet-derived Growth Factor Receptor Alpha, Mouse 1
PGFRB_MOUSE P05622 CHEMBL2749 Platelet-derived Growth Factor Receptor Beta, Mouse 1
PHKG1_HUMAN Q16816 CHEMBL4004 Phosphorylase Kinase Gamma Subunit 1, Human 1
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase Kinase Gamma Subunit 2, Human 1
PI42B_HUMAN P78356 CHEMBL5667 Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta, Human 1
PI51A_HUMAN Q99755 CHEMBL5969 Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha, Human 1
PIM2_HUMAN Q9P1W9 CHEMBL4523 Serine/threonine-protein Kinase PIM2, Human 1
PIM3_HUMAN Q86V86 CHEMBL5407 Serine/threonine-protein Kinase PIM3, Human 1
PK3C3_HUMAN Q8NEB9 CHEMBL1075165 Phosphatidylinositol 3-kinase Catalytic Subunit Type 3, Human 1
PKN1_HUMAN Q16512 CHEMBL3384 Protein Kinase N1, Human 1
PKN2_HUMAN Q16513 CHEMBL3032 Protein Kinase N2, Human 1
PLK2_HUMAN Q9NYY3 CHEMBL5938 Serine/threonine-protein Kinase PLK2, Human 1
PTK6_HUMAN Q13882 CHEMBL4601 Tyrosine-protein Kinase BRK, Human 1
RIOK1_HUMAN Q9BRS2 CHEMBL5975 Serine/threonine-protein Kinase RIO1, Human 1
RIOK3_HUMAN O14730 CHEMBL5659 Serine/threonine-protein Kinase RIO3, Human 1
RIPK2_HUMAN O43353 CHEMBL5014 Serine/threonine-protein Kinase RIPK2, Human 1
ROCK2_RAT Q62868 CHEMBL5490 Rho-associated Protein Kinase 2, Rat 1
ROS1_HUMAN P08922 CHEMBL5568 Proto-oncogene Tyrosine-protein Kinase ROS, Human 1
SIK1_HUMAN P57059 CHEMBL6082 Serine/threonine-protein Kinase SIK1, Human 1
SIK2_HUMAN Q9H0K1 CHEMBL5699 Serine/threonine-protein Kinase SIK2, Human 1
SLK_HUMAN Q9H2G2 CHEMBL4202 Serine/threonine-protein Kinase 2, Human 1
SRMS_HUMAN Q9H3Y6 CHEMBL5703 Tyrosine-protein Kinase Srms, Human 1
SRPK2_HUMAN P78362 CHEMBL5668 Serine/threonine-protein Kinase SRPK2, Human 1
ST17A_HUMAN Q9UEE5 CHEMBL4525 Serine/threonine-protein Kinase 17A, Human 1
ST32B_HUMAN Q9NY57 CHEMBL5912 Serine/threonine-protein Kinase 32B, Human 1
ST32C_HUMAN Q86UX6 CHEMBL5405 Serine/threonine-protein Kinase 32C, Human 1
ST38L_HUMAN Q9Y2H1 CHEMBL4851 Serine/threonine-protein Kinase 38-like, Human 1
STK10_HUMAN O94804 CHEMBL3981 Serine/threonine-protein Kinase 10, Human 1
STK11_HUMAN Q15831 CHEMBL5606 Serine/threonine-protein Kinase 11, Human 1
STK16_HUMAN O75716 CHEMBL3938 Serine/threonine-protein Kinase 16, Human 1
STK24_HUMAN Q9Y6E0 CHEMBL5082 Serine/threonine-protein Kinase 24, Human 1
STK25_HUMAN O00506 CHEMBL5552 Serine/threonine-protein Kinase 25, Human 1
STK33_HUMAN Q9BYT3 CHEMBL6005 Serine/threonine-protein Kinase 33, Human 1
STK36_HUMAN Q9NRP7 CHEMBL4312 Serine/threonine-protein Kinase 36, Human 1
STK3_MOUSE Q9JI10 CHEMBL4310 Serine/threonine-protein Kinase MST2, Mouse 1
STK4_HUMAN Q13043 CHEMBL4598 Serine/threonine-protein Kinase MST1, Human 1
SYK_HUMAN Q15046 CHEMBL5575 Lysyl-tRNA Synthetase, Human 1
TAB1_HUMAN Q15750 CHEMBL5605 Mitogen-activated Protein Kinase Kinase Kinase 7-interacting Protein 1, Human 1
TBA1A_RAT P68370 CHEMBL4139 Tubulin Alpha-1 Chain, Rat 1
TEC_HUMAN P42680 CHEMBL4246 Tyrosine-protein Kinase TEC, Human 1
TESK1_HUMAN Q15569 CHEMBL5604 Dual Specificity Testis-specific Protein Kinase 1, Human 1
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 1
TIE1_HUMAN P35590 CHEMBL5274 Tyrosine-protein Kinase Receptor Tie-1, Human 1
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 1
TLK1_HUMAN Q9UKI8 CHEMBL5388 Serine/threonine-protein Kinase Tousled-like 1, Human 1
TLK2_HUMAN Q86UE8 CHEMBL5404 Serine/threonine-protein Kinase Tousled-like 2, Human 1
TNI3K_HUMAN Q59H18 CHEMBL5260 Serine/threonine-protein Kinase TNNI3K, Human 1
TNIK_HUMAN Q9UKE5 CHEMBL4527 TRAF2- And NCK-interacting Kinase, Human 1
TNK1_HUMAN Q13470 CHEMBL5334 Non-receptor Tyrosine-protein Kinase TNK1, Human 1
TOPK_HUMAN Q96KB5 CHEMBL4896 PDZ-binding Kinase, Human 1
TSSK1_HUMAN Q9BXA7 CHEMBL6003 Testis-specific Serine/threonine-protein Kinase 1, Human 1
TTK_HUMAN P33981 CHEMBL3983 Dual Specificity Protein Kinase TTK, Human 1
TXK_HUMAN P42681 CHEMBL4367 Tyrosine-protein Kinase TXK, Human 1
TYRO3_HUMAN Q06418 CHEMBL5314 Tyrosine-protein Kinase Receptor TYRO3, Human 1
ULK3_MOUSE Q3U3Q1 CHEMBL3832 ULK3 Kinase, Mouse 1
VGFR2_MOUSE P35918 CHEMBL3337 Vascular Endothelial Growth Factor Receptor 2, Mouse 1
VGFR3_MOUSE P35917 CHEMBL4758 Vascular Endothelial Growth Factor Receptor 3, Mouse 1
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 1
YES_HUMAN P07947 CHEMBL2073 Tyrosine-protein Kinase YES, Human 1
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 1
Z100201 Z100201 CHEMBL612422 Splenocytes (Spleen Cells) 1
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 1
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 1
Z50512 Z50512 CHEMBL369 Cavia Porcellus 1
Z80120 Z80120 CHEMBL614285 DLD-1 (Colon Adenocarcinoma Cells) 1
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 1
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 1
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 1
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 1
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 1
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 1
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 1
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 1
Z81289 Z81289 CHEMBL615004 DOV13 (Ovarian Carcinoma Cells) 1
ZAP70_HUMAN P43403 CHEMBL2803 Tyrosine-protein Kinase ZAP-70, Human 1

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