UCSF

HERG, Human (2,874 Compounds)

Swissprot:
KCNH2_HUMAN
Stitch:
KCNH2_HUMAN
UniProt:
Q12809
ChEMBL:
CHEMBL240
Reactome:
REACT_75770
PDB:
1BYW (DOCK)
1UJL (DOCK)
2L0W (DOCK)
2L1M (DOCK)
2L4R (DOCK)
KCNH2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 2,874 203 156 161
Binding ≤ 1μM 1,069 78 69 71
Functional ≤ 10μM 79 37 36 34

Reactome Network (1)

Reactome ID Description Species
REACT_75770 Voltage gated Potassium channels Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
KCNA1_HUMAN Q09470 CHEMBL2309 Voltage-gated Potassium Channel Subunit Kv1.1, Human 2
KCNA2_HUMAN P16389 CHEMBL2086 Voltage-gated Potassium Channel Subunit Kv1.2, Human 2
KCNA3_HUMAN P22001 CHEMBL4633 Voltage-gated Potassium Channel Subunit Kv1.3, Human 24
KCNA4_HUMAN P22459 CHEMBL4205 Voltage-gated Potassium Channel Subunit Kv1.4, Human 2
KCNA5_HUMAN P22460 CHEMBL4306 Voltage-gated Potassium Channel Subunit Kv1.5, Human 26
KCND3_HUMAN Q9UK17 CHEMBL1964 Voltage-gated Potassium Channel Subunit Kv4.3, Human 47
KCNH1_HUMAN O95259 CHEMBL3841 Voltage-gated Potassium Channel Subunit Kv10.1, Human 1
KCNQ1_HUMAN P51787 CHEMBL1866 Voltage-gated Potassium Channel Subunit Kv7.1, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
KCNH2_CAVPO O08703 CHEMBL5557 Potassium Voltage-gated Channel Subfamily H Member 2, Guinea Pig 16 1 1 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
KCNH1_HUMAN O95259 CHEMBL3841 Voltage-gated Potassium Channel Subunit Kv10.1, Human 1 1 1 0

Clustered By Gene (0)

Clustered By Organism (4)

Code Description Substances Purchasable Natural In Man
KCNH2-1-E HERG (cluster #1 Of 5), Eukaryotic 1,730 79 64 65
KCNH2-2-E HERG (cluster #2 Of 5), Eukaryotic 112 19 10 13
KCNH2-3-E HERG (cluster #3 Of 5), Eukaryotic 141 7 6 6
KCNH2-4-E HERG (cluster #4 Of 5), Eukaryotic 136 7 4 4
KCNH2-5-E HERG (cluster #5 Of 5), Eukaryotic 807 98 78 79
Uniprot Swissprot Chembl Description Number Shared
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 298
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 278
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 259
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 255
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 189
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 188
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 134
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 132
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 121
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 104
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 101
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 95
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 81
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 79
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 72
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 69
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 60
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 60
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 55
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 55
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 53
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 51
HDAC1_HUMAN Q13547 CHEMBL325 Histone Deacetylase 1, Human 51
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 50
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 50
SC6A9_HUMAN P48067 CHEMBL2337 Glycine Transporter 1, Human 50
KCND3_HUMAN Q9UK17 CHEMBL1964 Voltage-gated Potassium Channel Subunit Kv4.3, Human 47
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 43
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 42
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 40
OPRX_HUMAN P41146 CHEMBL2014 Nociceptin Receptor, Human 39
CNR2_HUMAN P34972 CHEMBL253 Cannabinoid CB2 Receptor, Human 38
ACHA7_RAT Q05941 CHEMBL4980 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat 33
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 32
FNTA_HUMAN P49354 CHEMBL271 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human 31
FNTB_HUMAN P49356 CHEMBL272 Protein Farnesyltransferase Beta Subunit, Human 31
HYES_HUMAN P34913 CHEMBL2409 Epoxide Hydratase, Human 31
HYES_RAT P80299 CHEMBL5669 Epoxide Hydrolase 2, Rat 31
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 27
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 27
CAC1I_HUMAN Q9P0X4 CHEMBL5558 Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Human 26
KIF11_HUMAN P52732 CHEMBL4581 Kinesin-like Protein 1, Human 26
SCN5A_HUMAN Q14524 CHEMBL1980 Sodium Channel Protein Type V Alpha Subunit, Human 26
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 25
KCNQ1_CAVPO O70344 CHEMBL5135 Voltage-gated Potassium Channel Subunit Kv7.1, Guinea Pig 25
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 24
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 24
KCNA3_HUMAN P22001 CHEMBL4633 Voltage-gated Potassium Channel Subunit Kv1.3, Human 24
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 23
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 22
DPP4_HUMAN P27487 CHEMBL284 Dipeptidyl Peptidase IV, Human 22
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 22
FNTA_RAT Q04631 CHEMBL4432 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat 22
FNTB_RAT Q02293 CHEMBL4890 Protein Farnesyltransferase Beta Subunit, Rat 22
KCNA5_HUMAN P22460 CHEMBL4306 Voltage-gated Potassium Channel Subunit Kv1.5, Human 22
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 21
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 21
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 21
SC6A5_HUMAN Q9Y345 CHEMBL3060 Glycine Transporter 2, Human 21
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 21
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 21
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 20
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 20
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 20
CATK_HUMAN P43235 CHEMBL268 Cathepsin K, Human 19
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 19
PGTB1_HUMAN P53609 CHEMBL4135 Geranylgeranyl Transferase Type I Beta Subunit, Human 19
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 19
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 19
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 19
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 18
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 18
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 18
CAC1C_HUMAN Q13936 CHEMBL1940 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human 18
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 17
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 17
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 17
RENI_HUMAN P00797 CHEMBL286 Renin, Human 17
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 16
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 16
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 16
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 16
NK3R_HUMAN P29371 CHEMBL4429 Neurokinin 3 Receptor, Human 16
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 15
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 15
NPY1R_HUMAN P25929 CHEMBL4777 Neuropeptide Y Receptor Type 1, Human 15
PDE5A_HUMAN O76074 CHEMBL1827 Phosphodiesterase 5A, Human 15
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 15
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 14
CAC1G_HUMAN O43497 CHEMBL4641 Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Human 14
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 14
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 14
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 14
CATS_HUMAN P25774 CHEMBL2954 Cathepsin S, Human 13
PDE4A_HUMAN P27815 CHEMBL254 Phosphodiesterase 4A, Human 13
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 12
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 12
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 12
NPY5R_HUMAN Q15761 CHEMBL4561 Neuropeptide Y Receptor Type 5, Human 12
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 12
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 12
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 11
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 11
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 11
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 11
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 11
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate Receptor Ionotropic, AMPA 2, Human 11
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 11
SCN9A_HUMAN Q15858 CHEMBL4296 Sodium Channel Protein Type IX Alpha Subunit, Human 11
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 10
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 10
CASR_HUMAN P41180 CHEMBL1878 Calcium Sensing Receptor, Human 10
DPP2_HUMAN Q9UHL4 CHEMBL3976 Dipeptidyl Peptidase II, Human 10
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 10
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 10
CCR5_MACFA P61814 CHEMBL1075263 C-C Chemokine Receptor Type 5, Macfa 9
LKHA4_HUMAN P09960 CHEMBL4618 Leukotriene A4 Hydrolase, Human 9
LKHA4_MOUSE P24527 CHEMBL3738 Leukotriene A4 Hydrolase, Mouse 9
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 9
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 8
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 8
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 8
MC4R_HUMAN P32245 CHEMBL259 Melanocortin Receptor 4, Human 8
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 8
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 8
PPARA_HUMAN Q07869 CHEMBL239 Peroxisome Proliferator-activated Receptor Alpha, Human 8
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 8
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 7
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 7
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 7
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 7
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 7
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 7
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 7
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 7
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 7
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 7
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 7
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 7
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 7
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 7
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 7
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 7
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 7
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 7
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 7
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 7
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 7
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 7
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 6
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 6
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 6
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 6
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 6
HDAC3_HUMAN O15379 CHEMBL1829 Histone Deacetylase 3, Human 6
HRH3_MOUSE P58406 CHEMBL3263 Histamine H3 Receptor, Mouse 6
NR1H4_HUMAN Q96RI1 CHEMBL2047 Bile Acid Receptor FXR, Human 6
SSR5_HUMAN P35346 CHEMBL1792 Somatostatin Receptor 5, Human 6
Z50594 Z50594 CHEMBL375 Mus Musculus 6
5HT3B_HUMAN O95264 CHEMBL3895 Serotonin 3b (5-HT3b) Receptor, Human 5
5HT3C_HUMAN Q8WXA8 CHEMBL4795 Serotonin 3c (5-HT3c) Receptor, Human 5
5HT3D_HUMAN Q70Z44 CHEMBL4673 Serotonin 3d (5-HT3d) Receptor, Human 5
5HT3E_HUMAN A5X5Y0 CHEMBL3812 Serotonin 3e (5-HT3e) Receptor, Human 5
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 5
5HT5B_RAT P35365 CHEMBL2619 Serotonin 5b (5-HT5b) Receptor, Rat 5
5HT6R_RAT P31388 CHEMBL3372 Serotonin 6 (5-HT6) Receptor, Rat 5
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 5
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 5
BRS3_HUMAN P32247 CHEMBL4080 Bombesin Like Receptor 3, Human 5
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 5
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 5
CAC1D_RAT P27732 CHEMBL4132 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat 5
CETP_HUMAN P11597 CHEMBL3572 Cholesteryl Ester Transfer Protein, Human 5
CNR1_RAT P20272 CHEMBL3571 Cannabinoid CB1 Receptor, Rat 5
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 5
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 5
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 5
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 5
HDAC2_HUMAN Q92769 CHEMBL1937 Histone Deacetylase 2, Human 5
HS90A_HUMAN P07900 CHEMBL3880 Heat Shock Protein HSP 90-alpha, Human 5
MDR1_MOUSE P06795 CHEMBL3467 P-glycoprotein 1, Mouse 5
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 5
PRGR_HUMAN P06401 CHEMBL208 Progesterone Receptor, Human 5
SC6A3_MOUSE Q61327 CHEMBL2799 Dopamine Transporter, Mouse 5
SMO_HUMAN Q99835 CHEMBL5971 Smoothened Homolog, Human 5
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 4
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 4
BACE1_HUMAN P56817 CHEMBL4822 Beta-secretase 1, Human 4
CAC1F_HUMAN O60840 CHEMBL5593 Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human 4
CAC1S_HUMAN Q13698 CHEMBL3805 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human 4
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 4
DPP8_HUMAN Q6V1X1 CHEMBL4657 Dipeptidyl Peptidase VIII, Human 4
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 4
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 Receptor, Guinea Pig 4
HYEP_HUMAN P07099 CHEMBL1968 Epoxide Hydrolase 1, Human 4
KCND2_RAT Q63881 CHEMBL1075227 Potassium Voltage-gated Channel Subfamily D Member 2, Rat 4
MDR3_MOUSE P21447 CHEMBL2573 P-glycoprotein 3, Mouse 4
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 4
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 4
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 4
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 4
Z104288 Z104288 CHEMBL1907594 Neuronal Acetylcholine Receptor; Alpha3/beta4 4
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 3
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 3
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 3
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 3
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 3
ACES_TORCA P04058 CHEMBL4780 Acetylcholinesterase, Torca 3
ACHA7_HUMAN P36544 CHEMBL2492 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human 3
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 3
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 3
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 3
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 3
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 3
ADRB2_RAT P10608 CHEMBL3754 Beta-2 Adrenergic Receptor, Rat 3
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 3
BKRB1_HUMAN P46663 CHEMBL4308 Bradykinin B1 Receptor, Human 3
CA2D1_HUMAN P54289 CHEMBL1919 Voltage-gated Calcium Channel Alpha2/delta Subunit 1, Human 3
CA2D2_HUMAN Q9NY47 CHEMBL3896 Voltage-gated Calcium Channel Alpha2/delta Subunit 2, Human 3
CCR2_MOUSE P51683 CHEMBL5412 C-C Chemokine Receptor Type 2, Mouse 3
CCR4_HUMAN P51679 CHEMBL2414 C-C Chemokine Receptor Type 4, Human 3
CDK1_MOUSE P11440 CHEMBL4084 Cyclin-dependent Kinase 1, Mouse 3
DPP9_HUMAN Q86TI2 CHEMBL4793 Dipeptidyl Peptidase IX, Human 3
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 3
GASR_RAT P30553 CHEMBL3508 Cholecystokinin B Receptor, Rat 3
GYRA_ECOLI P0AES4 CHEMBL1858 DNA Gyrase Subunit A, Ecoli 3
GYRB_ECOLI P0AES6 CHEMBL1826 DNA Gyrase Subunit B, Ecoli 3
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 Receptor, Human 3
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 3
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 3
KPCE_RAT P09216 CHEMBL3424 Protein Kinase C Epsilon, Rat 3
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 3
LEF_BACAN P15917 CHEMBL4372 Anthrax Lethal Factor, Bacan 3
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 3
NOS2_HUMAN P35228 CHEMBL4481 Nitric Oxide Synthase, Inducible, Human 3
O77823_PIG O77823 CHEMBL3333 Phosphodiesterase 4A, Pig 3
P97706_RAT P97706 CHEMBL4957 Sodium Channel Protein Type VI Alpha Subunit, Rat 3
PARC_STAAU P0C1U9 CHEMBL4088 Topoisomerase IV Subunit A, Staau 3
PDE11_HUMAN Q9HCR9 CHEMBL2717 Phosphodiesterase 11A, Human 3
PDE1A_HUMAN P54750 CHEMBL3421 Phosphodiesterase 1A, Human 3
PDE1B_HUMAN Q01064 CHEMBL4425 Phosphodiesterase 1B, Human 3
PDE1C_HUMAN Q14123 CHEMBL4619 Phosphodiesterase 1C, Human 3
PDE3A_HUMAN Q14432 CHEMBL241 Phosphodiesterase 3A, Human 3
PDE3B_HUMAN Q13370 CHEMBL290 Phosphodiesterase 3B, Human 3
PDR5_YEAST P33302 CHEMBL1697658 Pleiotropic ABC Efflux Transporter Of Multiple Drugs, Yeast 3
PGFRA_MOUSE P26618 CHEMBL3466 Platelet-derived Growth Factor Receptor Alpha, Mouse 3
PGFRB_MOUSE P05622 CHEMBL2749 Platelet-derived Growth Factor Receptor Beta, Mouse 3
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 3
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 3
S22A1_HUMAN O15245 CHEMBL5685 Solute Carrier Family 22 Member 1, Human 3
SC6A2_MOUSE O55192 CHEMBL2370 Norepinephrine Transporter, Mouse 3
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 3
SCN5A_RAT P15389 CHEMBL3866 Sodium Channel Protein Type V Alpha Subunit, Rat 3
SCNAA_HUMAN Q9Y5Y9 CHEMBL5451 Sodium Channel Protein Type X Alpha Subunit, Human 3
SCNAA_MOUSE Q6QIY3 CHEMBL5158 Sodium Channel Protein Type 10 Subunit Alpha, Mouse 3
VGFR2_MOUSE P35918 CHEMBL3337 Vascular Endothelial Growth Factor Receptor 2, Mouse 3
Z104282 Z104282 CHEMBL1907588 Acetylcholine Receptor; Alpha1/beta1/delta/gamma 3
Z104283 Z104283 CHEMBL1907589 Neuronal Acetylcholine Receptor; Alpha4/beta2 3
Z104297 Z104297 CHEMBL1907603 Glutamate NMDA Receptor; GRIN1/GRIN2B 3
Z50512 Z50512 CHEMBL369 Cavia Porcellus 3
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 3
5HT2A_PIG P50129 CHEMBL2490 Serotonin 2a (5-HT2a) Receptor, Pig 2
5HT3A_CAVPO O70212 CHEMBL3666 Serotonin 3a (5-HT3a) Receptor, Guinea Pig 2
5HT3B_MOUSE Q9JHJ5 CHEMBL3781 Serotonin 3b (5-HT3b) Receptor, Mouse 2
5HT4R_CAVPO O70528 CHEMBL5017 Serotonin 4 (5-HT4) Receptor, Guinea Pig 2
6PGD_HUMAN P52209 CHEMBL3404 6-phosphogluconate Dehydrogenase, Human 2
ACES_BOVIN P23795 CHEMBL4768 Acetylcholinesterase, Bovin 2
ACES_ELEEL O42275 CHEMBL4078 Acetylcholinesterase, Eleel 2
ACES_MOUSE P21836 CHEMBL3198 Acetylcholinesterase, Mouse 2
ACES_RAT P37136 CHEMBL3199 Acetylcholinesterase, Rat 2
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 2
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 2
ADA1B_MESAU P18841 CHEMBL3122 Alpha-1b Adrenergic Receptor, Mesau 2
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 2
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 2
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 2
ATS4_HUMAN O75173 CHEMBL2318 ADAMTS4, Human 2
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 2
C3SLN2_ECOLX C3SLN2 CHEMBL1287603 DNA Gyrase Subunit B, Ecolx 2
CAC1C_RABIT P15381 CHEMBL2830 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rabit 2
CAC1E_RAT Q07652 CHEMBL4115 Voltage-gated R-type Calcium Channel Alpha-1E Subunit, Rat 2
CAC1S_RAT Q02485 CHEMBL4108 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat 2
CCR3_HUMAN P51677 CHEMBL3473 C-C Chemokine Receptor Type 3, Human 2
CCR3_MOUSE P51678 CHEMBL3406 C-C Chemokine Receptor Type 3, Mouse 2
CHLE_HORSE P81908 CHEMBL5763 Cholinesterase, Horse 2
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 2
CLAT_RAT P32738 CHEMBL3945 Choline Acetylase, Rat 2
CP17A_HUMAN P05093 CHEMBL3522 Cytochrome P450 17A1, Human 2
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 2
CP2J2_HUMAN P51589 CHEMBL3491 Cytochrome P450 2J2, Human 2
CP51A_HUMAN Q16850 CHEMBL3849 Cytochrome P450 51, Human 2
DHI1_HUMAN P28845 CHEMBL4235 11-beta-hydroxysteroid Dehydrogenase 1, Human 2
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 2
ERG_HUMAN P11308 CHEMBL1293191 Transcriptional Regulator ERG, Human 2
G6PD_YEAST P11412 CHEMBL1075249 Glucose-6-phosphate 1-dehydrogenase, Yeast 2
GHSR_HUMAN Q92847 CHEMBL4616 Ghrelin Receptor, Human 2
GHSR_MOUSE Q99P50 CHEMBL3428 Ghrelin Receptor, Mouse 2
GLR_HUMAN P47871 CHEMBL1985 Glucagon Receptor, Human 2
GYRA_MYCTU Q07702 CHEMBL4165 DNA Gyrase Subunit A, Myctu 2
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 2
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 2
HRP1_PLAFA P05227 CHEMBL1923 Histidine-rich Protein, Plafa 2
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 2
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 2
KCC2A_MOUSE P11798 CHEMBL3347 CaM Kinase II Alpha, Mouse 2
KCC2B_MOUSE P28652 CHEMBL4735 CaM Kinase II Beta, Mouse 2
KCC2G_MOUSE Q923T9 CHEMBL4456 CaM Kinase II Gamma, Mouse 2
KCNA1_HUMAN Q09470 CHEMBL2309 Voltage-gated Potassium Channel Subunit Kv1.1, Human 2
KCNA2_HUMAN P16389 CHEMBL2086 Voltage-gated Potassium Channel Subunit Kv1.2, Human 2
KCNA3_MOUSE P16390 CHEMBL4818 Voltage-gated Potassium Channel Subunit Kv1.3, Mouse 2
KCNA4_HUMAN P22459 CHEMBL4205 Voltage-gated Potassium Channel Subunit Kv1.4, Human 2
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 2
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 2
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 2
NMD3A_RAT Q9R1M7 CHEMBL342 Glutamate [NMDA] Receptor Subunit 3A, Rat 2
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 2
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 2
NOS1_HUMAN P29475 CHEMBL3568 Nitric-oxide Synthase, Brain, Human 2
NQO2_HUMAN P16083 CHEMBL3959 Quinone Reductase 2, Human 2
NR1I2_HUMAN O75469 CHEMBL3401 Pregnane X Receptor, Human 2
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 2
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 2
PDE10_HUMAN Q9Y233 CHEMBL4409 Phosphodiesterase 10A, Human 2
PDE1B_RAT Q01066 CHEMBL3665 Phosphodiesterase 1B, Rat 2
PDE4A_RAT P54748 CHEMBL4964 Phosphodiesterase 4A, Rat 2
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 2
PDE4B_RAT P14646 CHEMBL3382 Phosphodiesterase 4B, Rat 2
PDE4C_HUMAN Q08493 CHEMBL291 Phosphodiesterase 4C, Human 2
PDE4C_RAT P14644 CHEMBL4562 Phosphodiesterase 4C, Rat 2
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 2
PDE4D_RAT P14270 CHEMBL2712 Phosphodiesterase 4D, Rat 2
PDE6A_HUMAN P16499 CHEMBL3878 Phosphodiesterase 6A, Human 2
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 2
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 2
Q47245_ECOLX Q47245 CHEMBL1287602 DNA Gyrase Subunit A, Ecolx 2
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 2
Q864F1_PIG Q864F1 CHEMBL3634 Phosphodiesterase 5, Pig 2
Q965D5_PLAFA Q965D5 CHEMBL4150 Enoyl-acyl-carrier Protein Reductase, Plafa 2
Q965D6_PLAFA Q965D6 CHEMBL4513 3-oxoacyl-acyl-carrier Protein Reductase, Plafa 2
Q965D7_PLAFA Q965D7 CHEMBL4512 Fatty Acid Synthase, Plafa 2
Q9JKC1_RAT Q9JKC1 CHEMBL3403 Butyrylcholinesterase, Rat 2
Q9N1N9_HORSE Q9N1N9 CHEMBL5077 Butyrylcholinesterase, Horse 2
SC6A3_BOVIN P27922 CHEMBL2986 Dopamine Transporter, Bovin 2
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 2
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 2
TOP2A_HUMAN P11388 CHEMBL1806 DNA Topoisomerase II Alpha, Human 2
TOP2B_HUMAN Q02880 CHEMBL3396 DNA Topoisomerase II Beta, Human 2
VGFR1_MOUSE P35969 CHEMBL3516 Vascular Endothelial Growth Factor Receptor 1, Mouse 2
VGFR3_MOUSE P35917 CHEMBL4758 Vascular Endothelial Growth Factor Receptor 3, Mouse 2
Z100251 Z100251 CHEMBL612442 Monoclonal Antibody (mAb) 2E2 2
Z100275 Z100275 CHEMBL613898 Hemozoin 2
Z100759 Z100759 CHEMBL614167 T-lymphocytes 2
Z104290 Z104290 CHEMBL1907596 Neuronal Acetylcholine Receptor; Alpha4/beta2 2
Z50466 Z50466 CHEMBL368 Trypanosoma Cruzi 2
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 2
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 1
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 1
ACCN3_HUMAN Q9UHC3 CHEMBL5368 Amiloride-sensitive Cation Channel 3, Human 1
ACH10_RAT Q9JLB5 CHEMBL3461 Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Rat 1
ACHA2_HUMAN Q15822 CHEMBL1794 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human 1
ACHA2_RAT P12389 CHEMBL2584 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat 1
ACHA3_HUMAN P32297 CHEMBL3068 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human 1
ACHA3_RAT P04757 CHEMBL3818 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat 1
ACHA4_HUMAN P43681 CHEMBL1882 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human 1
ACHA4_MOUSE O70174 CHEMBL4457 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Mouse 1
ACHA4_RAT P09483 CHEMBL307 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat 1
ACHA5_RAT P20420 CHEMBL4960 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Rat 1
ACHA6_RAT P43143 CHEMBL4747 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Rat 1
ACHA7_MOUSE P49582 CHEMBL3365 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Mouse 1
ACHA9_RAT P43144 CHEMBL2585 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Rat 1
ACHA_RAT P25108 CHEMBL3599 Acetylcholine Receptor Protein Alpha Chain, Rat 1
ACHA_TORCA P02710 CHEMBL3097 Acetylcholine Receptor Protein Alpha Chain, Torca 1
ACHB2_HUMAN P17787 CHEMBL1883 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human 1
ACHB2_RAT P12390 CHEMBL3001 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat 1
ACHB3_HUMAN Q05901 CHEMBL2586 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human 1
ACHB3_RAT P12391 CHEMBL4568 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat 1
ACHB4_HUMAN P30926 CHEMBL3002 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human 1
ACHB4_RAT P12392 CHEMBL2658 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat 1
ACHB_RAT P25109 CHEMBL2666 Acetylcholine Receptor Protein Beta Chain, Rat 1
ACHB_TORCA P02712 CHEMBL3803 Acetylcholine Receptor Protein Beta Chain, Torca 1
ACHD_HUMAN Q07001 CHEMBL3011 Acetylcholine Receptor Protein Delta Chain, Human 1
ACHD_TORCA P02718 CHEMBL3916 Acetylcholine Receptor Protein Delta Chain, Torca 1
ACHG_TORCA P02714 CHEMBL4019 Acetylcholine Receptor Protein Gamma Chain, Torca 1
ACHP_LYMST P58154 CHEMBL6084 Acetylcholine-binding Protein, Lymst 1
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 1
ADA2A_MOUSE Q01338 CHEMBL4075 Alpha-2a Adrenergic Receptor, Mouse 1
ADA2A_PIG P18871 CHEMBL2350 Alpha-2a Adrenergic Receptor, Pig 1
ADA2B_MOUSE P30545 CHEMBL2405 Alpha-2b Adrenergic Receptor, Mouse 1
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 1
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 1
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 1
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 1
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 1
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 1
AMPC_ECOLI P00811 CHEMBL2026 Beta-lactamase, Ecoli 1
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 1
AP2S1_RAT P62744 CHEMBL1697667 AP-2 Complex Subunit Sigma, Rat 1
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 1
AURKC_HUMAN Q9UQB9 CHEMBL3935 Serine/threonine-protein Kinase Aurora-C, Human 1
B0BL08_ECOLX B0BL08 CHEMBL5441 Dihydrofolate Reductase, Ecolx 1
BACE2_HUMAN Q9Y5Z0 CHEMBL2525 Beta Secretase 2, Human 1
BCL2_HUMAN P10415 CHEMBL4860 Apoptosis Regulator Bcl-2, Human 1
BRS3_MOUSE O54798 CHEMBL1075140 Bombesin Receptor Subtype-3, Mouse 1
BRS3_RAT Q8K418 CHEMBL1075111 Bombesin Receptor Subtype-3, Rat 1
C11B1_BOVIN P15150 CHEMBL2927 Cytochrome P450 11B1, Bovin 1
C11B1_HUMAN P15538 CHEMBL1908 Cytochrome P450 11B1, Human 1
C11B2_HUMAN P19099 CHEMBL2722 Cytochrome P450 11B2, Human 1
CAC1A_RAT P54282 CHEMBL4417 Voltage-gated P/Q-type Calcium Channel Alpha-1A Subunit, Rat 1
CAC1B_HUMAN Q00975 CHEMBL4478 Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Human 1
CAC1B_RAT Q02294 CHEMBL5107 Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Rat 1
CAC1G_RAT O54898 CHEMBL4257 Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Rat 1
CAC1H_HUMAN O95180 CHEMBL1859 Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Human 1
CAC1H_RAT Q9EQ60 CHEMBL5134 Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Rat 1
CAC1I_RAT Q9Z0Y8 CHEMBL5459 Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Rat 1
CALM_HUMAN P62158 CHEMBL6093 Calmodulin, Human 1
CALRL_HUMAN Q16602 CHEMBL3798 Calcitonin Gene-related Peptide Type 1 Receptor, Human 1
CASR_BOVIN P35384 CHEMBL1075316 Extracellular Calcium-sensing Receptor, Bovin 1
CATD_HUMAN P07339 CHEMBL2581 Cathepsin D, Human 1
CCKAR_HUMAN P32238 CHEMBL1901 Cholecystokinin A Receptor, Human 1
CCKAR_RAT P30551 CHEMBL2871 Cholecystokinin A Receptor, Rat 1
CCL2_HUMAN P13500 CHEMBL1649052 C-C Motif Chemokine 2, Human 1
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 1
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCND3_HUMAN P30281 CHEMBL2422 G1/S-specific Cyclin D3, Human 1
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 1
CCNT1_HUMAN O60563 CHEMBL2108 Cyclin T1, Human 1
CCR2_RAT O55193 CHEMBL1293204 C-C Chemokine Receptor Type 2, Rat 1
CCR3_RAT O54814 CHEMBL3928 C-C Chemokine Receptor Type 3, Rat 1
CCR5_MOUSE P51682 CHEMBL3676 C-C Chemokine Receptor Type 5, Mouse 1
CCR7_HUMAN P32248 CHEMBL4594 C-C Chemokine Receptor Type 7, Human 1
CCR8_HUMAN P51685 CHEMBL4596 C-C Chemokine Receptor Type 8, Human 1
CCR9_HUMAN P51686 CHEMBL5815 C-C Chemokine Receptor Type 9, Human 1
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 1
CHK1_HUMAN O14757 CHEMBL4630 Serine/threonine-protein Kinase Chk1, Human 1
CNCG_BOVIN P22571 CHEMBL4606 Phosphodiesterase 6H, Bovin 1
CNCG_HUMAN Q13956 CHEMBL2341 Phosphodiesterase 6H, Human 1
CNR1_MOUSE P47746 CHEMBL3037 Cannabinoid CB1 Receptor, Mouse 1
CNR2_MOUSE P47936 CHEMBL5373 Cannabinoid CB2 Receptor, Mouse 1
CNR2_RAT Q9QZN9 CHEMBL2470 Cannabinoid CB2 Receptor, Rat 1
CNRG_BOVIN P04972 CHEMBL5111 Phosphodiesterase 6G, Bovin 1
CNRG_HUMAN P18545 CHEMBL2415 Phosphodiesterase 6G, Human 1
CP11A_RAT P14137 CHEMBL5246 Cytochrome P450 11A1, Rat 1
CP17A_RAT P11715 CHEMBL4430 Cytochrome P450 17A1, Rat 1
CP21A_HUMAN P08686 CHEMBL2759 Cytochrome P450 21, Human 1
CP24A_HUMAN Q07973 CHEMBL4521 Cytochrome P450 24A1, Human 1
CP3A4_HUMAN P08684 CHEMBL340 Cytochrome P450 3A4, Human 1
CP51A_RAT Q64654 CHEMBL4981 Cytochrome P450 51, Rat 1
CP51_MYCTU P0A512 CHEMBL5090 Lanosterol 14-alpha Demethylase, Myctu 1
CP7A1_RAT P18125 CHEMBL2339 Cytochrome P450 7A1, Rat 1
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 1
CXCR4_HUMAN P61073 CHEMBL2107 C-X-C Chemokine Receptor Type 4, Human 1
CXCR4_RAT O08565 CHEMBL5556 C-X-C Chemokine Receptor Type 4, Rat 1
CYSP_TRYCR P25779 CHEMBL3563 Cruzipain, Trycr 1
D4A3N4_RAT D4A3N4 CHEMBL2679 Brain Adenylate Cyclase 1, Rat 1
DPP4_MOUSE P28843 CHEMBL3883 Dipeptidyl Peptidase IV, Mouse 1
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 1
DRTS_PLAFK P13922 CHEMBL1939 Dihydrofolate Reductase, Plafk 1
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 1
DYR1_ECOLX P00382 CHEMBL2627 Dihydrofolate Reductase Type 1, Ecolx 1
DYR_ECOLI P0ABQ4 CHEMBL1809 Dihydrofolate Reductase, Ecoli 1
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 1
DYR_LACCA P00381 CHEMBL2902 Dihydrofolate Reductase, Lacca 1
DYR_MOUSE P00375 CHEMBL4564 Dihydrofolate Reductase, Mouse 1
DYR_PNECA P16184 CHEMBL1926 Dihydrofolate Reductase, Pneca 1
DYR_STAAU P0A017 CHEMBL1681620 Dihydrofolate Reductase, Staau 1
E1BN64_BOVIN E1BN64 CHEMBL5129 Phosphodiesterase 3B, Bovin 1
EBP_CAVPO Q60490 CHEMBL5525 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Guinea Pig 1
ERBB4_HUMAN Q15303 CHEMBL3009 Receptor Protein-tyrosine Kinase ErbB-4, Human 1
ERG1_RAT P52020 CHEMBL4241 Squalene Monooxygenase, Rat 1
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 1
ESR2_HUMAN Q92731 CHEMBL242 Estrogen Receptor Beta, Human 1
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 1
FDFT_HUMAN P37268 CHEMBL3338 Squalene Synthetase, Human 1
FFAR1_HUMAN O14842 CHEMBL4422 Free Fatty Acid Receptor 1, Human 1
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 1
FNTA_BOVIN P29702 CHEMBL2377 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Bovin 1
FNTB_BOVIN P49355 CHEMBL4671 Protein Farnesyltransferase Beta Subunit, Bovin 1
GASR_HUMAN P32239 CHEMBL298 Cholecystokinin B Receptor, Human 1
GASR_MOUSE P56481 CHEMBL2854 Cholecystokinin B Receptor, Mouse 1
GNRHR_RAT P30969 CHEMBL3066 Gonadotropin-releasing Hormone Receptor, Rat 1
GRPR_HUMAN P30550 CHEMBL4959 Gastrin Releasing Peptide Receptor, Human 1
HDA10_HUMAN Q969S8 CHEMBL5103 Histone Deacetylase 10, Human 1
HDA11_HUMAN Q96DB2 CHEMBL3310 Histone Deacetylase 11, Human 1
HDAC4_HUMAN P56524 CHEMBL3524 Histone Deacetylase 4, Human 1
HDAC5_HUMAN Q9UQL6 CHEMBL2563 Histone Deacetylase 5, Human 1
HDAC6_HUMAN Q9UBN7 CHEMBL1865 Histone Deacetylase 6, Human 1
HDAC7_HUMAN Q8WUI4 CHEMBL2716 Histone Deacetylase 7, Human 1
HDAC8_HUMAN Q9BY41 CHEMBL3192 Histone Deacetylase 8, Human 1
HDAC9_HUMAN Q9UKV0 CHEMBL4145 Histone Deacetylase 9, Human 1
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 1
KCNH1_HUMAN O95259 CHEMBL3841 Voltage-gated Potassium Channel Subunit Kv10.1, Human 1
KCNH2_CAVPO O08703 CHEMBL5557 Potassium Voltage-gated Channel Subfamily H Member 2, Guinea Pig 1
KCNN4_HUMAN O15554 CHEMBL4305 Intermediate Conductance Calcium-activated Potassium Channel Protein 4, Human 1
KCNQ1_HUMAN P51787 CHEMBL1866 Voltage-gated Potassium Channel Subunit Kv7.1, Human 1
KHK_HUMAN P50053 CHEMBL1275212 Ketohexokinase, Human 1
MCHR1_MOUSE Q8JZL2 CHEMBL4730 Melanin-concentrating Hormone Receptor 1, Mouse 1
MCHR1_RAT P97639 CHEMBL1075228 Melanin-concentrating Hormone Receptor 1, Rat 1
MCHR2_HUMAN Q969V1 CHEMBL5038 Melanin-concentrating Hormone Receptor 2, Human 1
MDHM_PIG P00346 CHEMBL3444 Malate Dehydrogenase Mitochondrial, Pig 1
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 1
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 1
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 1
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 1
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 1
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 1
MT3_HUMAN P25713 CHEMBL1250357 Metallothionein-3, Human 1
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 1
NMBR_HUMAN P28336 CHEMBL3636 Neuromedin B Receptor, Human 1
NOS2_MOUSE P29477 CHEMBL3464 Nitric Oxide Synthase, Inducible, Mouse 1
NOS3_HUMAN P29474 CHEMBL4803 Nitric-oxide Synthase, Endothelial, Human 1
NPM_HUMAN P06748 CHEMBL5178 Nucleophosmin, Human 1
O30463_MYCAV O30463 CHEMBL5457 Dihydrofolate Reductase, Mycav 1
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 1
PARP1_HUMAN P09874 CHEMBL3105 Poly [ADP-ribose] Polymerase-1, Human 1
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 1
PDE10_RAT Q9QYJ6 CHEMBL6140 CAMP And CAMP-inhibited CGMP 3',5'-cyclic Phosphodiesterase 10A, Rat 1
PDE1A_BOVIN P14100 CHEMBL3774 Phosphodiesterase 1A, Bovin 1
PDE1B_BOVIN Q01061 CHEMBL2650 Phosphodiesterase 1B, Bovin 1
PDE1C_RAT Q63421 CHEMBL2651 Phosphodiesterase 1C, Rat 1
PDE2A_HUMAN O00408 CHEMBL2652 Phosphodiesterase 2A, Human 1
PDE5A_BOVIN Q28156 CHEMBL3478 Phosphodiesterase 5A, Bovin 1
PDE5A_RAT O54735 CHEMBL4567 Phosphodiesterase 5A, Rat 1
PDE6A_BOVIN P11541 CHEMBL3741 Phosphodiesterase 6A, Bovin 1
PDE6B_BOVIN P23439 CHEMBL2713 Phosphodiesterase 6B, Bovin 1
PDE6B_HUMAN P35913 CHEMBL3659 Phosphodiesterase 6B, Human 1
PDE6C_BOVIN P16586 CHEMBL3479 Phosphodiesterase 6C, Bovin 1
PDE6C_HUMAN P51160 CHEMBL3977 Phosphodiesterase 6C, Human 1
PDE6D_BOVIN Q95142 CHEMBL5110 Phosphodiesterase 6D, Bovin 1
PDE6D_HUMAN O43924 CHEMBL3860 Phosphodiesterase 6D, Human 1
PDE9A_HUMAN O76083 CHEMBL3535 Phosphodiesterase 9A, Human 1
PE2R1_HUMAN P34995 CHEMBL1811 Prostanoid EP1 Receptor, Human 1
PE2R2_HUMAN P43116 CHEMBL1881 Prostanoid EP2 Receptor, Human 1
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 1
PE2R3_RAT P34980 CHEMBL5674 Prostaglandin E2 Receptor EP3 Subtype, Rat 1
PI2R_HUMAN P43119 CHEMBL1995 Prostanoid IP Receptor, Human 1
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 1
Q4WNT5_ASPFU Q4WNT5 CHEMBL1681623 14-alpha Sterol Demethylase Cyp51A, Aspfu 1
Q533H1_FELCA Q533H1 CHEMBL5226 Urotensin II Receptor, Felca 1
Q5EI73_PLAFA Q5EI73 CHEMBL4737 Protein Farnesyltransferase Alpha Subunit, Plafa 1
Q5EI74_PLAFA Q5EI74 CHEMBL1741264 Protein Farnesyltransferase Beta Subunit, Plafa 1
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 1
Q865E1_MACMU Q865E1 CHEMBL5299 Histamine Receptor H3, Macmu 1
Q8AWE3_CHICK Q8AWE3 CHEMBL2669 Serine-threonine Protein Phosphatase 2A Regulatory Subunit, Chick 1
Q8BGP7_MOUSE Q8BGP7 CHEMBL2235 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Mouse 1
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1
Q96W81_ASPFM Q96W81 CHEMBL1681624 14-alpha Sterol Demethylase, Aspfm 1
Q9EPR9_RAT Q9EPR9 CHEMBL2740 Phosphodiesterase 1A, Rat 1
Q9XSW7_PIG Q9XSW7 CHEMBL3061 Phosphodiesterase 3A, Pig 1
S29A1_HUMAN Q99808 CHEMBL1997 Equilibrative Nucleoside Transporter 1, Human 1
SC6A3_MACFA Q9GJT6 CHEMBL5032 Dopamine Transporter, Macfa 1
SCN1A_RAT P04774 CHEMBL4906 Sodium Channel Protein Type I Alpha Subunit, Rat 1
SCN3A_RAT P08104 CHEMBL4966 Sodium Channel Protein Type III Alpha Subunit, Rat 1
SCN4A_HUMAN P35499 CHEMBL2072 Sodium Channel Protein Type IV Alpha Subunit, Human 1
SCN7A_HUMAN Q01118 CHEMBL3585 Sodium Channel Protein Type VII Alpha Subunit, Human 1
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 1
SCNBA_HUMAN Q9UI33 CHEMBL5167 Sodium Channel Protein Type XI Alpha Subunit, Human 1
THA_HUMAN P10827 CHEMBL1860 Thyroid Hormone Receptor Alpha, Human 1
THB_HUMAN P10828 CHEMBL1947 Thyroid Hormone Receptor Beta-1, Human 1
TRPV1_HUMAN Q8NER1 CHEMBL4794 Vanilloid Receptor, Human 1
TRPV1_RAT O35433 CHEMBL5102 Vanilloid Receptor, Rat 1
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 1
TRY2_RAT P00763 CHEMBL4290 Trypsin II, Rat 1
TRYB1_HUMAN Q15661 CHEMBL2617 Tryptase Beta-1, Human 1
TSPO_RAT P16257 CHEMBL4552 Peripheral-type Benzodiazepine Receptor, Rat 1
TYTR_TRYCR P28593 CHEMBL5131 Trypanothione Reductase, Trycr 1
UR2R_HUMAN Q9UKP6 CHEMBL3764 Urotensin II Receptor, Human 1
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 1
Z100267 Z100267 CHEMBL612409 Anti-estrogen Binding Site (AEBS) 1
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 1
Z101682 Z101682 CHEMBL613915 BK Polyomavirus 1
Z102275 Z102275 CHEMBL613575 Hypothalamus 1
Z102380 Z102380 CHEMBL613680 Ileum 1
Z103204 Z103204 CHEMBL1075389 A427 1
Z104281 Z104281 CHEMBL1907587 Neuronal Acetylcholine Receptor; Alpha3/beta2 1
Z104284 Z104284 CHEMBL1907590 Neuronal Acetylcholine Receptor; Alpha2/beta4 1
Z104285 Z104285 CHEMBL1907591 Neuronal Acetylcholine Receptor; Alpha4/beta4 1
Z104286 Z104286 CHEMBL1907592 Neuronal Acetylcholine Receptor; Alpha2/beta2 1
Z104287 Z104287 CHEMBL1907593 Neuronal Acetylcholine Receptor; Alpha3/beta4 1
Z104289 Z104289 CHEMBL1907595 Neuronal Acetylcholine Receptor; Alpha4/beta4 1
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1
Z50038 Z50038 CHEMBL612328 Plasmodium Yoelii Yoelii 1
Z50591 Z50591 CHEMBL613489 Bos Taurus 1
Z50636 Z50636 CHEMBL613725 Sindbis Virus 1
Z50796 Z50796 CHEMBL614874 Monkey 1
Z80091 Z80091 CHEMBL614557 CHO-hD3 1
Z80107 Z80107 CHEMBL614564 COS-7 (Kidney Cells) 1
Z80120 Z80120 CHEMBL614285 DLD-1 (Colon Adenocarcinoma Cells) 1
Z80133 Z80133 CHEMBL614294 EMT6 (Mammary Carcinoma Cells) 1
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 1
Z80232 Z80232 CHEMBL614128 MCF7-VP 1
Z80334 Z80334 CHEMBL613828 NG108-15 (Neuroblastoma-glioma Hybrid Cells) 1
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 1
Z80364 Z80364 CHEMBL614218 P388/ADR (Lymphoma Cells) 1
Z80532 Z80532 CHEMBL614774 T-24 (Bladder Carcinoma Cells) 1
Z80711 Z80711 CHEMBL613829 NCI/ADR-RES (Breast Carcinoma Cells) 1
Z80773 Z80773 CHEMBL614456 CHRC/5 Cell Line 1
Z80774 Z80774 CHEMBL614457 CHRC5 Cell Line 1
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 1
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 1
Z81008 Z81008 CHEMBL614788 Human Breast Cancer Cell Lines 1
Z81034 Z81034 CHEMBL614004 A2780 (Ovarian Carcinoma Cells) 1
Z81047 Z81047 CHEMBL614685 Human T-cell Line 1
Z81138 Z81138 CHEMBL613872 ScN2a (Scrapie-infected Neuroblastoma Cells) 1
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 1

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