UCSF

Tryptase Beta-1, Human (397 Compounds)

Swissprot:
TRYB1_HUMAN
Stitch:
TRYB1_HUMAN
UniProt:
Q15661
ChEMBL:
CHEMBL2617
Reactome:
REACT_118682
PDB:
1LTO (DOCK)
2F9N (DOCK)
2F9O (DOCK)
2F9P (DOCK)
2ZEB (DOCK)
2ZEC (DOCK)
4A6L (DOCK)
TPSAB1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 397 1 0 2
Binding ≤ 1μM 339 1 0 2

Reactome Network (1)

Reactome ID Description Species
REACT_118682 Activation of Matrix Metalloproteinases Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ELNE_HUMAN P08246 CHEMBL248 Leukocyte Elastase, Human 3
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 5
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 87
TRY2_HUMAN P07478 CHEMBL3159 Trypsin II, Human 38
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
TRYB1_MOUSE Q02844 CHEMBL4749 Tryptase Alpha/beta-1, Mouse 1 0 0 0
TRYB1_RAT P27435 CHEMBL3320 Tryptase Alpha/beta-1, Rat 1 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
TRYD_HUMAN Q9BZJ3 CHEMBL2402 Tryptase Delta, Human 231
TRYG1_HUMAN Q9NRR2 CHEMBL4955 Tryptase Gamma, Human 224
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 87
TRY3_HUMAN P35030 CHEMBL4551 Trypsin III, Human 41
TRY2_HUMAN P07478 CHEMBL3159 Trypsin II, Human 38
PLMN_RAT Q01177 CHEMBL3204 Plasminogen, Rat 7
UROK_HUMAN P00749 CHEMBL3286 Urokinase-type Plasminogen Activator, Human 6
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 5
TRY1_BOVIN P00760 CHEMBL3769 Trypsin I, Bovin 4
ELNE_HUMAN P08246 CHEMBL248 Leukocyte Elastase, Human 3
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
THRB_BOVIN P00735 CHEMBL4471 Thrombin, Bovin 1
TRYB1_MOUSE Q02844 CHEMBL4749 Tryptase Alpha/beta-1, Mouse 1
TRYB1_RAT P27435 CHEMBL3320 Tryptase Alpha/beta-1, Rat 1
TRYT_CANFA P15944 CHEMBL4700 Tryptase, Canine 1