UCSF

Trypsin II, Human (415 Compounds)

Swissprot:
TRY2_HUMAN
Stitch:
TRY2_HUMAN
UniProt:
P07478
ChEMBL:
CHEMBL3159
Reactome:
REACT_118682
REACT_115574
REACT_150401
PDB:
PRSS2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 415 34 2 6
Binding ≤ 1μM 177 3 1 5

Reactome Network (3)

Uniprot Swissprot Chembl Description Number Shared
KLKB1_HUMAN P03952 CHEMBL2000 Plasma Kallikrein, Human 1
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 12
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 414
TRYB1_HUMAN Q15661 CHEMBL2617 Tryptase Beta-1, Human 38

Alpha-defensins

Uniprot Swissprot Chembl Description Number Shared
TRY3_HUMAN P35030 CHEMBL4551 Trypsin III, Human 88
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
TRY2_BOVIN Q29463 CHEMBL4472 Trypsin II, Bovin 234 1 1 8
TRY2_RAT P00763 CHEMBL4290 Trypsin II, Rat 17 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 1,764 48 13 44
TRY3_HUMAN P35030 CHEMBL4551 Trypsin III, Human 101 1 0 0
TRYB1_HUMAN Q15661 CHEMBL2617 Tryptase Beta-1, Human 397 1 0 2
TRYD_HUMAN Q9BZJ3 CHEMBL2402 Tryptase Delta, Human 231 1 0 1
TRYG1_HUMAN Q9NRR2 CHEMBL4955 Tryptase Gamma, Human 225 1 0 1

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
TRY2-1-E Trypsin II (cluster #1 Of 3), Eukaryotic 584 3 2 14
TRY2-2-E Trypsin II (cluster #2 Of 3), Eukaryotic 6 0 0 0
TRY2-3-E Trypsin II (cluster #3 Of 3), Eukaryotic 83 31 1 1
Uniprot Swissprot Chembl Description Number Shared
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 414
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 311
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 201
TRY3_HUMAN P35030 CHEMBL4551 Trypsin III, Human 88
TRYB1_HUMAN Q15661 CHEMBL2617 Tryptase Beta-1, Human 38
FA7_HUMAN P08709 CHEMBL3991 Coagulation Factor VII, Human 36
TPA_HUMAN P00750 CHEMBL1873 Tissue-type Plasminogen Activator, Human 32
TF_HUMAN P13726 CHEMBL4081 Coagulation Factor III, Human 30
FA9_HUMAN P00740 CHEMBL2016 Coagulation Factor IX, Human 17
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 12
TRY1_BOVIN P00760 CHEMBL3769 Trypsin I, Bovin 7
UROK_HUMAN P00749 CHEMBL3286 Urokinase-type Plasminogen Activator, Human 6
THRB_BOVIN P00735 CHEMBL4471 Thrombin, Bovin 3
TRY2_BOVIN Q29463 CHEMBL4472 Trypsin II, Bovin 2
TRYD_HUMAN Q9BZJ3 CHEMBL2402 Tryptase Delta, Human 2
TRYG1_HUMAN Q9NRR2 CHEMBL4955 Tryptase Gamma, Human 2
ANT3_HUMAN P01008 CHEMBL1950 Antithrombin-III Precursor, Human 1
FA10_BOVIN P00743 CHEMBL3656 Coagulation Factor X, Bovin 1
KLK1_HUMAN P06870 CHEMBL2319 Kallikrein 1, Human 1
KLKB1_HUMAN P03952 CHEMBL2000 Plasma Kallikrein, Human 1
PLMN_RAT Q01177 CHEMBL3204 Plasminogen, Rat 1
PROC_HUMAN P04070 CHEMBL4444 Vitamin K-dependent Protein C, Human 1
THRB_RAT P18292 CHEMBL3078 Thrombin, Rat 1
TRYB1_MOUSE Q02844 CHEMBL4749 Tryptase Alpha/beta-1, Mouse 1
TRYB1_RAT P27435 CHEMBL3320 Tryptase Alpha/beta-1, Rat 1
TRYT_CANFA P15944 CHEMBL4700 Tryptase, Canine 1