ZINC 12

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Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	415	34	2	6
Binding ≤ 1μM	177	3	1	5

Reactome ID	Description	Species
REACT_118682	Activation of Matrix Metalloproteinases	Homo sapiens
REACT_115574	Alpha-defensins	Homo sapiens
REACT_150401	Collagen degradation	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
KLKB1_HUMAN	P03952	CHEMBL2000	Plasma Kallikrein, Human	1
PLMN_HUMAN	P00747	CHEMBL1801	Plasminogen, Human	12
TRY1_HUMAN	P07477	CHEMBL209	Trypsin I, Human	414
TRYB1_HUMAN	Q15661	CHEMBL2617	Tryptase Beta-1, Human	38

Uniprot	Swissprot	Chembl	Description	Number Shared
TRY3_HUMAN	P35030	CHEMBL4551	Trypsin III, Human	88

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
TRY2_BOVIN	Q29463	CHEMBL4472	Trypsin II, Bovin	234	1	1	8
TRY2_RAT	P00763	CHEMBL4290	Trypsin II, Rat	17	0	0	0

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
TRY1_HUMAN	P07477	CHEMBL209	Trypsin I, Human	1,764	48	13	44
TRY3_HUMAN	P35030	CHEMBL4551	Trypsin III, Human	101	1	0	0
TRYB1_HUMAN	Q15661	CHEMBL2617	Tryptase Beta-1, Human	397	1	0	2
TRYD_HUMAN	Q9BZJ3	CHEMBL2402	Tryptase Delta, Human	231	1	0	1
TRYG1_HUMAN	Q9NRR2	CHEMBL4955	Tryptase Gamma, Human	225	1	0	1

Code	Description	Substances	Purchasable	Natural	In Man
TRY2-1-E	Trypsin II (cluster #1 Of 3), Eukaryotic	584	3	2	14
TRY2-2-E	Trypsin II (cluster #2 Of 3), Eukaryotic	6	0	0	0
TRY2-3-E	Trypsin II (cluster #3 Of 3), Eukaryotic	83	31	1	1

Uniprot	Swissprot	Chembl	Description	Number Shared
TRY1_HUMAN	P07477	CHEMBL209	Trypsin I, Human	414
THRB_HUMAN	P00734	CHEMBL204	Thrombin, Human	311
FA10_HUMAN	P00742	CHEMBL244	Coagulation Factor X, Human	201
TRY3_HUMAN	P35030	CHEMBL4551	Trypsin III, Human	88
TRYB1_HUMAN	Q15661	CHEMBL2617	Tryptase Beta-1, Human	38
FA7_HUMAN	P08709	CHEMBL3991	Coagulation Factor VII, Human	36
TPA_HUMAN	P00750	CHEMBL1873	Tissue-type Plasminogen Activator, Human	32
TF_HUMAN	P13726	CHEMBL4081	Coagulation Factor III, Human	30
FA9_HUMAN	P00740	CHEMBL2016	Coagulation Factor IX, Human	17
PLMN_HUMAN	P00747	CHEMBL1801	Plasminogen, Human	12
TRY1_BOVIN	P00760	CHEMBL3769	Trypsin I, Bovin	7
UROK_HUMAN	P00749	CHEMBL3286	Urokinase-type Plasminogen Activator, Human	6
THRB_BOVIN	P00735	CHEMBL4471	Thrombin, Bovin	3
TRY2_BOVIN	Q29463	CHEMBL4472	Trypsin II, Bovin	2
TRYD_HUMAN	Q9BZJ3	CHEMBL2402	Tryptase Delta, Human	2
TRYG1_HUMAN	Q9NRR2	CHEMBL4955	Tryptase Gamma, Human	2
ANT3_HUMAN	P01008	CHEMBL1950	Antithrombin-III Precursor, Human	1
FA10_BOVIN	P00743	CHEMBL3656	Coagulation Factor X, Bovin	1
KLK1_HUMAN	P06870	CHEMBL2319	Kallikrein 1, Human	1
KLKB1_HUMAN	P03952	CHEMBL2000	Plasma Kallikrein, Human	1
PLMN_RAT	Q01177	CHEMBL3204	Plasminogen, Rat	1
PROC_HUMAN	P04070	CHEMBL4444	Vitamin K-dependent Protein C, Human	1
THRB_RAT	P18292	CHEMBL3078	Thrombin, Rat	1
TRYB1_MOUSE	Q02844	CHEMBL4749	Tryptase Alpha/beta-1, Mouse	1
TRYB1_RAT	P27435	CHEMBL3320	Tryptase Alpha/beta-1, Rat	1
TRYT_CANFA	P15944	CHEMBL4700	Tryptase, Canine	1