UCSF
Image of 1,2,3,6-tetrahydropyridine

Identity 99% 90% 80% 70% Substructure

1,2,3,6-tetrahydropyridine

PubMed — Wikipedia — Google

Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
1 1 6 5 1 0 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 423 45,436 392 2,210 28 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 71 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 71 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 66 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 65 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 62 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 61 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 58 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 52 Annotations Catalogs SMILES SDF Mol2 Flexibase
FKB1A_HUMAN P62942 CHEMBL1902 FK506-binding Protein 1A, Human 49 Annotations Catalogs SMILES SDF Mol2 Flexibase
FKB1A_HUMAN P62942 CHEMBL1902 FK506-binding Protein 1A, Human 47 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 27 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_ELEEL O42275 CHEMBL4078 Acetylcholinesterase, Eleel 17 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 17 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP4_HUMAN P27487 CHEMBL284 Dipeptidyl Peptidase IV, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP4_HUMAN P27487 CHEMBL284 Dipeptidyl Peptidase IV, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITA3_HUMAN P26006 CHEMBL3525 Integrin Alpha-3, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_ELEEL O42275 CHEMBL4078 Acetylcholinesterase, Eleel 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP8_HUMAN Q6V1X1 CHEMBL4657 Dipeptidyl Peptidase VIII, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNMT_BOVIN P10938 CHEMBL2331 Phenylethanolamine N-methyltransferase, Bovin 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
OXYR_HUMAN P30559 CHEMBL2049 Oxytocin Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNMT_BOVIN P10938 CHEMBL2331 Phenylethanolamine N-methyltransferase, Bovin 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNMT_HUMAN P11086 CHEMBL4617 Phenylethanolamine N-methyltransferase, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
V1AR_HUMAN P37288 CHEMBL1889 Vasopressin V1a Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
TRY2_HUMAN P07478 CHEMBL3159 Trypsin II, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
VMAT2_RAT Q01827 CHEMBL4828 Synaptic Vesicular Amine Transporter, Rat 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase