UCSF

Acetylcholinesterase, Eleel (827 Compounds)

Swissprot:
ACES_ELEEL
Stitch:
ACES_ELEEL
UniProt:
O42275
ChEMBL:
CHEMBL4078

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 827 43 30 14
Binding ≤ 1μM 577 34 17 12

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACES_BOVIN P23795 CHEMBL4768 Acetylcholinesterase, Bovin 332 18 13 14
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 1,893 166 81 42
ACES_MOUSE P21836 CHEMBL3198 Acetylcholinesterase, Mouse 174 27 11 14
ACES_RAT P37136 CHEMBL3199 Acetylcholinesterase, Rat 712 37 13 17
ACES_TORCA P04058 CHEMBL4780 Acetylcholinesterase, Torca 144 38 13 18

Clustered By Gene (0)

Clustered By Organism (11)

Code Description Substances Purchasable Natural In Man
ACES-1-E Acetylcholinesterase (cluster #1 Of 12), Eukaryotic 1,833 54 43 24
ACES-10-E Acetylcholinesterase (cluster #10 Of 12), Eukaryotic 750 87 33 18
ACES-11-E Acetylcholinesterase (cluster #11 Of 12), Eukaryotic 0 0 0 0
ACES-12-E Acetylcholinesterase (cluster #12 Of 12), Eukaryotic 4 3 2 0
ACES-2-E Acetylcholinesterase (cluster #2 Of 12), Eukaryotic 427 36 9 6
ACES-3-E Acetylcholinesterase (cluster #3 Of 12), Eukaryotic 24 1 4 0
ACES-4-E Acetylcholinesterase (cluster #4 Of 12), Eukaryotic 9 3 5 1
ACES-5-E Acetylcholinesterase (cluster #5 Of 12), Eukaryotic 336 29 9 8
ACES-6-E Acetylcholinesterase (cluster #6 Of 12), Eukaryotic 62 1 1 1
ACES-7-E Acetylcholinesterase (cluster #7 Of 12), Eukaryotic 1 1 0 0
ACES-8-E Acetylcholinesterase (cluster #8 Of 12), Eukaryotic 36 5 3 1
ACES-9-E Acetylcholinesterase (cluster #9 Of 12), Eukaryotic 18 10 3 4
Uniprot Swissprot Chembl Description Number Shared
CHLE_HORSE P81908 CHEMBL5763 Cholinesterase, Horse 250
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 187
Q9N1N9_HORSE Q9N1N9 CHEMBL5077 Butyrylcholinesterase, Horse 129
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 77
ACES_RAT P37136 CHEMBL3199 Acetylcholinesterase, Rat 39
ACES_BOVIN P23795 CHEMBL4768 Acetylcholinesterase, Bovin 37
ACES_TORCA P04058 CHEMBL4780 Acetylcholinesterase, Torca 36
Q9JKC1_RAT Q9JKC1 CHEMBL3403 Butyrylcholinesterase, Rat 10
ACES_MOUSE P21836 CHEMBL3198 Acetylcholinesterase, Mouse 9
Z104298 Z104298 CHEMBL1907604 Glutamate NMDA Receptor; GRIN1/GRIN2A 9
ACM2_PIG P06199 CHEMBL4781 Muscarinic Acetylcholine Receptor M2, Pig 7
Z104297 Z104297 CHEMBL1907603 Glutamate NMDA Receptor; GRIN1/GRIN2B 6
CLAT_RAT P32738 CHEMBL3945 Choline Acetylase, Rat 4
AGTRB_RAT P29089 CHEMBL263 Angiotensin II Type 1b (AT-1b) Receptor, Rat 3
CHLE_MOUSE Q03311 CHEMBL2528 Butyrylcholinesterase, Mouse 3
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 2
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 2
ACHE_HUMAN Q04844 CHEMBL2484 Acetylcholine Receptor Protein Epsilon Chain, Human 1
ACM1_MOUSE P12657 CHEMBL3733 Muscarinic Acetylcholine Receptor M1, Mouse 1
ACM2_MOUSE Q9ERZ4 CHEMBL3197 Muscarinic Acetylcholine Receptor M2, Mouse 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
BACE1_HUMAN P56817 CHEMBL4822 Beta-secretase 1, Human 1
HNMT_RAT Q01984 CHEMBL3241 Histamine N-methyltransferase, Rat 1
LOX1_SOYBN P08170 CHEMBL4586 Seed Lipoxygenase-1, Soybn 1
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 1
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 1
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 1
PLCG1_BOVIN P08487 CHEMBL5566 1-phosphatidylinositol-4,5-bisphosphate Phosphodiesterase Gamma-1, Bovin 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1