UCSF
Image of Pyran-2-one

Identity 99% 90% 80% 70% Substructure

Pyran-2-one

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Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
1 1 7 5 0 2 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 1,614 10,056 143 238 4 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 37 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 34 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_RAT O70536 CHEMBL285 Acyl Coenzyme A:cholesterol Acyltransferase 1, Rat 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_RAT O70536 CHEMBL285 Acyl Coenzyme A:cholesterol Acyltransferase 1, Rat 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
HCAR2_HUMAN Q8TDS4 CHEMBL3785 Nicotinic Acid Receptor 1, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
TERT_HUMAN O14746 CHEMBL2916 Telomerase Reverse Transcriptase, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
CTRC_HUMAN Q99895 CHEMBL2386 Chymotrypsin C, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q43570_TOBAC Q43570 CHEMBL1293200 Zn Finger Protein, Tobac 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q43570_TOBAC Q43570 CHEMBL1293200 Zn Finger Protein, Tobac 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPO1_THEAQ P19821 CHEMBL3564 Taq Polymerase 1, Theaq 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_ELEEL O42275 CHEMBL4078 Acetylcholinesterase, Eleel 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CTRC_HUMAN Q99895 CHEMBL2386 Chymotrypsin C, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DCMC_HUMAN O95822 CHEMBL4698 Malonyl-CoA Decarboxylase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DCMC_HUMAN O95822 CHEMBL4698 Malonyl-CoA Decarboxylase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DHI1_HUMAN P28845 CHEMBL4235 11-beta-hydroxysteroid Dehydrogenase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DHI1_HUMAN P28845 CHEMBL4235 11-beta-hydroxysteroid Dehydrogenase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FA12_HUMAN P00748 CHEMBL2821 Coagulation Factor XII, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GSHR_HUMAN P00390 CHEMBL2755 Glutathione Reductase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GST_PLAFA Q8MU52 CHEMBL1697656 Glutathione S-transferase, Plafa 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
XPO1_HUMAN O14980 CHEMBL5661 Exportin-1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100766 Z100766 CHEMBL613712 Radical Scavenging Activity 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50426 Z50426 CHEMBL612856 Plasmodium Falciparum (isolate K1 / Thailand) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80175 Z80175 CHEMBL614585 IMR-32 (Neuroblastoma Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase