UCSF

Nicotinic Acid Receptor 1, Human (365 Compounds)

Swissprot:
HCAR2_HUMAN
Stitch:
HCAR2_HUMAN
UniProt:
Q8TDS4
ChEMBL:
CHEMBL3785
Reactome:
REACT_14828
REACT_19231
REACT_163785

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 365 20 5 3
Binding ≤ 1μM 282 11 3 3
Functional ≤ 10μM 147 25 6 4

Reactome Network (3)

Reactome ID Description Species
REACT_14828 Class A/1 (Rhodopsin-like receptors) Homo sapiens
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_163785 Hydroxycarboxylic acid-binding receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
HCAR3_HUMAN P49019 CHEMBL4421 HM74 Nicotinic Acid GPCR, Human 30

Hydroxycarboxylic acid-binding receptors

Uniprot Swissprot Chembl Description Number Shared
HCAR3_HUMAN P49019 CHEMBL4421 HM74 Nicotinic Acid GPCR, Human 30
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
HCAR2_MOUSE Q9EP66 CHEMBL4420 HM74 Nicotinic Acid GPCR, Mouse 70 1 1 1
HCAR2_RAT Q80Z39 CHEMBL4731 HM74 Nicotinic Acid GPCR, Rat 19 8 3 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
HCAR3_HUMAN P49019 CHEMBL4421 HM74 Nicotinic Acid GPCR, Human 6 2 2 2

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
HCAR2-1-E HM74 Nicotinic Acid GPCR (cluster #1 Of 4), Eukaryotic 281 4 2 2
HCAR2-2-E HM74 Nicotinic Acid GPCR (cluster #2 Of 4), Eukaryotic 50 11 3 1
HCAR2-3-E HM74 Nicotinic Acid GPCR (cluster #3 Of 4), Eukaryotic 31 1 1 0
HCAR2-4-E HM74 Nicotinic Acid GPCR (cluster #4 Of 4), Eukaryotic 16 9 1 0
Uniprot Swissprot Chembl Description Number Shared
HCAR2_MOUSE Q9EP66 CHEMBL4420 HM74 Nicotinic Acid GPCR, Mouse 73
HCAR3_HUMAN P49019 CHEMBL4421 HM74 Nicotinic Acid GPCR, Human 30
HCAR2_RAT Q80Z39 CHEMBL4731 HM74 Nicotinic Acid GPCR, Rat 12
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 4
OXDA_HUMAN P14920 CHEMBL5485 D-amino-acid Oxidase, Human 1
Z50588 Z50588 CHEMBL373 Canis Familiaris 1

Most Common Rings