UCSF
Image of 1H-pyrazole

Identity 99% 90% 80% 70% Substructure

1H-pyrazole

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Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
1 1 5 3 2 0 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 37 314,639 1,108 18,049 8 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
AA1R_BOVIN P28190 CHEMBL4975 Adenosine A1 Receptor, Bovin 117 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 104 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 103 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA1R_BOVIN P28190 CHEMBL4975 Adenosine A1 Receptor, Bovin 98 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 86 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 73 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 71 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 70 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 70 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 65 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 56 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 49 Annotations Catalogs SMILES SDF Mol2 Flexibase
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 47 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 46 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 44 Annotations Catalogs SMILES SDF Mol2 Flexibase
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 39 Annotations Catalogs SMILES SDF Mol2 Flexibase
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 37 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 32 Annotations Catalogs SMILES SDF Mol2 Flexibase
CASR_HUMAN P41180 CHEMBL1878 Calcium Sensing Receptor, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
CASR_HUMAN P41180 CHEMBL1878 Calcium Sensing Receptor, Human 30 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 30 Annotations Catalogs SMILES SDF Mol2 Flexibase
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 30 Annotations Catalogs SMILES SDF Mol2 Flexibase
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 28 Annotations Catalogs SMILES SDF Mol2 Flexibase
IKKB_HUMAN O14920 CHEMBL1991 Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human 28 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 27 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 27 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 27 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 26 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 25 Annotations Catalogs SMILES SDF Mol2 Flexibase
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 25 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80548 Z80548 CHEMBL614245 THP-1 (Acute Monocytic Leukemia Cells) 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 23 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 23 Annotations Catalogs SMILES SDF Mol2 Flexibase
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 23 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80526 Z80526 CHEMBL612544 SW480 (Colon Adenocarcinoma Cells) 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
CNR2_MOUSE P47936 CHEMBL5373 Cannabinoid CB2 Receptor, Mouse 17 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 17 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
CNR2_MOUSE P47936 CHEMBL5373 Cannabinoid CB2 Receptor, Mouse 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
GCR_HUMAN P04150 CHEMBL2034 Glucocorticoid Receptor, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
TGFR2_HUMAN P37173 CHEMBL4267 TGF-beta Receptor Type II, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
CNR1_MOUSE P47746 CHEMBL3037 Cannabinoid CB1 Receptor, Mouse 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
GCR_HUMAN P04150 CHEMBL2034 Glucocorticoid Receptor, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
GCR_HUMAN P04150 CHEMBL2034 Glucocorticoid Receptor, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8SPQ9_CANFA Q8SPQ9 CHEMBL4033 Cyclooxygenase-2, Canine 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8SPQ9_CANFA Q8SPQ9 CHEMBL4033 Cyclooxygenase-2, Canine 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
CNR1_MOUSE P47746 CHEMBL3037 Cannabinoid CB1 Receptor, Mouse 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
DHB1_HUMAN P14061 CHEMBL3181 Estradiol 17-beta-dehydrogenase 1, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
IKKB_HUMAN O14920 CHEMBL1991 Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 10 Annotations Catalogs SMILES SDF Mol2 Flexibase