UCSF

HUVEC (Umbilical Vein Endothelial Cells) (772 Compounds)

Swissprot:
Z81057
Stitch:
Z81057
UniProt:
Z81057
ChEMBL:
CHEMBL613979

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Functional ≤ 10μM 772 60 26 26
ADME/T ≤ 10μM 118 11 8 4

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 140
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 98
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 98
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 53
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 44
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 43
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 43
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 42
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 36
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 34
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 24
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 24
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 23
Z80742 Z80742 CHEMBL614657 C6 (Glioma Cells) 22
Z81024 Z81024 CHEMBL396 NCI-H460 (Non-small Cell Lung Carcinoma) 19
PGFRA_RAT P20786 CHEMBL2513 Platelet-derived Growth Factor Receptor Alpha, Rat 17
PGFRB_RAT Q05030 CHEMBL4125 Platelet-derived Growth Factor Receptor Beta, Rat 17
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 17
Z80951 Z80951 CHEMBL614822 NIH3T3 (Fibroblasts) 16
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 15
Z80583 Z80583 CHEMBL391 Vero (Kidney Cells) 15
Z80018 Z80018 CHEMBL613859 A-375 (Malignant Melanoma Cells) 14
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 13
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 13
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 12
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 12
ITAL_HUMAN P20701 CHEMBL1803 Leukocyte Adhesion Glycoprotein LFA-1 Alpha, Human 11
ITB2_HUMAN P05107 CHEMBL3631 Integrin Beta-2, Human 11
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 11
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 11
Z81338 Z81338 CHEMBL614309 T-cells 11
Z81034 Z81034 CHEMBL614004 A2780 (Ovarian Carcinoma Cells) 10
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 9
Q862F3_BOVIN Q862F3 CHEMBL4262 Tubulin Alpha Chain, Bovin 8
Q862L2_BOVIN Q862L2 CHEMBL3752 Tubulin Alpha-1 Chain, Bovin 8
TBB2B_BOVIN Q6B856 CHEMBL3394 Tubulin Beta Chain, Bovin 8
Z100490 Z100490 CHEMBL612588 ASPC1 (Pancreatic Tumour Cell Line) 8
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 8
Z80013 Z80013 CHEMBL614513 A10 8
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 8
Z80291 Z80291 CHEMBL614181 MRC5 (Embryonic Lung Fibroblast Cells) 8
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 8
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 8
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 7
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 6
Z100495 Z100495 CHEMBL613880 BMEC (Brain Microvessel Endothelial Cells) 6
Z100742 Z100742 CHEMBL613300 MeWo (Melanoma Cells) 6
Z80035 Z80035 CHEMBL381 B16 (Melanoma Cells) 6
Z80229 Z80229 CHEMBL614326 MCF7-DOX (Breast Carcinoma Cells) 6
Z80902 Z80902 CHEMBL614150 HASMC (Aortic Smooth Muscle Cells) 6
Z103203 Z103203 CHEMBL1075388 A375 5
Z80120 Z80120 CHEMBL614285 DLD-1 (Colon Adenocarcinoma Cells) 5
Z80493 Z80493 CHEMBL614925 SK-OV-3 (Ovarian Carcinoma Cells) 5
Z80784 Z80784 CHEMBL614462 Col2 (Colon Carcinoma Cells) 5
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 5
Z81065 Z81065 CHEMBL613984 IGROV-1 (Ovarian Adenocarcinoma Cells) 5
Z100501 Z100501 CHEMBL613290 Lu1 (Lung Carcinoma Cells) 4
Z102306 Z102306 CHEMBL613606 Aorta 4
Z80005 Z80005 CHEMBL614077 3T3 (Fibroblast Cells) 4
Z80548 Z80548 CHEMBL614245 THP-1 (Acute Monocytic Leukemia Cells) 4
Z80852 Z80852 CHEMBL614069 A-431 (Epidermoid Carcinoma Cells) 4
ICAM1_HUMAN P05362 CHEMBL3070 Intercellular Adhesion Molecule-1, Human 3
LYAM2_HUMAN P16581 CHEMBL3890 Selectin E, Human 3
Z103205 Z103205 CHEMBL1075390 A431 3
Z50442 Z50442 CHEMBL366 Candida Albicans 3
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 3
Z80002 Z80002 CHEMBL614075 1A9 (Ovarian Adenocarcinoma Cells) 3
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 3
Z80125 Z80125 CHEMBL613508 DU-145 (Prostate Carcinoma) 3
Z80208 Z80208 CHEMBL614720 L5178Y (Lymphoma Cells) 3
Z81037 Z81037 CHEMBL613967 Human Ovarian Carcinoma Cell Line 3
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 3
Z81335 Z81335 CHEMBL612263 HCT-15 (Colon Adenocarcinoma Cells) 3
PGFRA_MOUSE P26618 CHEMBL3466 Platelet-derived Growth Factor Receptor Alpha, Mouse 2
PGFRB_MOUSE P05622 CHEMBL2749 Platelet-derived Growth Factor Receptor Beta, Mouse 2
Z100405 Z100405 CHEMBL613835 MV4-11 (Myeloid Leukemia Cells) 2
Z103208 Z103208 CHEMBL1075393 AU565 2
Z50426 Z50426 CHEMBL612856 Plasmodium Falciparum (isolate K1 / Thailand) 2
Z50436 Z50436 CHEMBL365 Filobasidiella Neoformans 2
Z50459 Z50459 CHEMBL367 Leishmania Donovani 2
Z50594 Z50594 CHEMBL375 Mus Musculus 2
Z80054 Z80054 CHEMBL614058 Caco-2 (Colon Adenocarcinoma Cells) 2
Z80164 Z80164 CHEMBL614580 HT-1080 (Fibrosarcoma Cells) 2
Z80178 Z80178 CHEMBL614040 J774.A1 (Macrophage Cells) 2
Z80253 Z80253 CHEMBL614342 MEF (Embryonic Fibroblast Cells) 2
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 2
Z80482 Z80482 CHEMBL614917 SK-MEL-2 (Melanoma Cells) 2
Z80485 Z80485 CHEMBL614919 SK-MEL-28 (Melanoma Cells) 2
Z80565 Z80565 CHEMBL614247 U-87 MG (Glioblastoma Cells) 2
Z80600 Z80600 CHEMBL613533 XF498 (Glioma Cells) 2
Z80704 Z80704 CHEMBL614358 BJ (Foreskin Fibroblast Cells) 2
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 2
Z80885 Z80885 CHEMBL614507 BEND (Brain Endothelial Cells) 2
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 1
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 1
CP3A4_HUMAN P08684 CHEMBL340 Cytochrome P450 3A4, Human 1
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 1
ESR2_HUMAN Q92731 CHEMBL242 Estrogen Receptor Beta, Human 1
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 1
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 1
Q25270_LEIDO Q25270 CHEMBL3186 Beta Tubulin, Leido 1
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 1
TBA1A_PIG P02550 CHEMBL3658 Tubulin Alpha Chain, Pig 1
TBA1A_RAT P68370 CHEMBL4139 Tubulin Alpha-1 Chain, Rat 1
TBA4A_HUMAN P68366 CHEMBL2070 Tubulin Alpha-1 Chain, Human 1
TBB1_HUMAN Q9H4B7 CHEMBL1915 Tubulin Beta-1 Chain, Human 1
TBB3_HUMAN Q13509 CHEMBL2597 Tubulin Beta-3 Chain, Human 1
TBB4A_HUMAN P04350 CHEMBL3838 Tubulin Beta-4 Chain, Human 1
TBB4B_HUMAN P68371 CHEMBL1848 Tubulin Beta-2 Chain, Human 1
TBB5_HUMAN P07437 CHEMBL5444 Tubulin Beta-5 Chain, Human 1
TBB8_HUMAN Q3ZCM7 CHEMBL4024 Tubulin Beta-8 Chain, Human 1
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 1
Z100201 Z100201 CHEMBL612422 Splenocytes (Spleen Cells) 1
Z100729 Z100729 CHEMBL613857 AEC (Aortic Endothelial Cells) 1
Z100768 Z100768 CHEMBL613836 TPC1 (Papillary Thyroid Carinoma Cells) 1
Z101767 Z101767 CHEMBL613966 Dengue Virus 2 1
Z103407 Z103407 CHEMBL1075592 SW1990 1
Z50501 Z50501 CHEMBL613109 Gallus Gallus 1
Z50512 Z50512 CHEMBL369 Cavia Porcellus 1
Z50587 Z50587 CHEMBL372 Homo Sapiens 1
Z50591 Z50591 CHEMBL613489 Bos Taurus 1
Z50599 Z50599 CHEMBL612672 Cowpox Virus 1
Z50641 Z50641 CHEMBL613730 West Nile Virus 1
Z50678 Z50678 CHEMBL612679 Respiratory Syncytial Virus 1
Z80025 Z80025 CHEMBL614519 ACHN (Renal Adenocarcinoma Cells) 1
Z80040 Z80040 CHEMBL614527 BHK-21 (Kidney Cells) 1
Z80071 Z80071 CHEMBL614028 CEM-0 (T-cell Leukemia) 1
Z80099 Z80099 CHEMBL614561 COLO 205 (Colon Adenocarcinoma Cells) 1
Z80101 Z80101 CHEMBL614562 COLO 320DM (Colon Adenocarcinoma Cells) 1
Z80121 Z80121 CHEMBL614286 DMS-79 (Small Cell Lung Carcinoma Cells) 1
Z80136 Z80136 CHEMBL614297 FM3A (Breast Carcinoma Cells) 1
Z80254 Z80254 CHEMBL614343 MES-SA (Uterine Sarcoma Cells) 1
Z80255 Z80255 CHEMBL613827 MES-SA/DxS (Uterine Sarcoma Cells) 1
Z80269 Z80269 CHEMBL614354 MKN-45 (Gastric Adenocarcinoma Cells) 1
Z80280 Z80280 CHEMBL614173 MNNG-HOS 1
Z80284 Z80284 CHEMBL614176 MOLT-3 (T-lymphoblastic Leukemia Cells) 1
Z80285 Z80285 CHEMBL614177 MOLT-4 (Acute T-lymphoblastic Leukemia Cells) 1
Z80335 Z80335 CHEMBL614200 NHDF 1
Z80353 Z80353 CHEMBL614212 OVCAR 1
Z80401 Z80401 CHEMBL614241 PSN1 1
Z80415 Z80415 CHEMBL614629 Ramos (Burkitts Lymhoma B-cells) 1
Z80418 Z80418 CHEMBL612557 RAW264.7 (Monocytic-macrophage Leukemia Cells) 1
Z80471 Z80471 CHEMBL614910 SH-SY5 (Bone Marrow Neuroblastoma Cells) 1
Z80472 Z80472 CHEMBL612542 SiHa (Cervical Squamous Cell Carcinoma) 1
Z80555 Z80555 CHEMBL615018 TSGH 1
Z80566 Z80566 CHEMBL612794 U-937 (Histiocytic Lymphoma Cells) 1
Z80608 Z80608 CHEMBL614393 ZR-75-1 (Breast Carcinoma Cells) 1
Z80640 Z80640 CHEMBL613102 786-0 (Renal Carcinoma Cells) 1
Z80697 Z80697 CHEMBL614279 Bel-7402 (Hepatoma Cells) 1
Z80711 Z80711 CHEMBL613829 NCI/ADR-RES (Breast Carcinoma Cells) 1
Z80792 Z80792 CHEMBL614466 Colon 26 (Colon Adenocarcinoma Cells) 1
Z80798 Z80798 CHEMBL614470 CPT30 Cell Line 1
Z80800 Z80800 CHEMBL614725 MIA PaCa-2 (Pancreatic Carcinoma Cells) 1
Z80847 Z80847 CHEMBL612250 FaDu (Pharyngeal Carcinoma Cells) 1
Z80896 Z80896 CHEMBL614805 NCI-H69 (Small Cell Lung Carcinoma Cells) 1
Z80900 Z80900 CHEMBL614807 HA22T Cell Line 1
Z80954 Z80954 CHEMBL614071 HFF (Foreskin Fibroblasts) 1
Z80967 Z80967 CHEMBL614831 Hone-1 Cell Line 1
Z81001 Z81001 CHEMBL614787 TSGH 9201 (Gastric Carcinoma Cells) 1
Z81135 Z81135 CHEMBL614793 L6 (Skeletal Muscle Myoblast Cells) 1
Z81233 Z81233 CHEMBL614117 M21 (Melanoma Cells) 1

Most Common Rings