ZINC 12

User Information

Not Authenticated — sign in

Active cart: Temporary Cart (0 items)

Navigation

About
- ZINC
- BCIRC
- Irwin Lab
- Shoichet Lab
- UCSF
- Acknowledgements
- Facts
- Usage
Search
- By:
- Text
- Structure
- Properties
- Catalogs
- ZINC
- Targets
- Rings
- Combination
Subsets
- By:
- Catalog
- Property
- Target
- Ring
- Cart
Help
- Introduction
- FAQ
- Scripting/API
- Quick Search
- Problems
- Filtering
- History
Social
- ZINC Fans
- Decoy Club
- DOCK Fans
- Facebook
- Twitter
- Blog
- Linkedin
Quick Search ZINC ID or SMILES

Names
Compounds (218)
Reactome (0)
Related By:
Pathway (0)
Organism (-1)
Gene (-1)
Org. Clust. (-1)
ChEMBL (136)
Rings (9)

U-937 (Histiocytic Lymphoma Cells) (218 Compounds)

Swissprot:: Z80566
Stitch:: Z80566
UniProt:: Z80566
ChEMBL:: CHEMBL612794

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Functional ≤ 10μM	218	17	13	11
ADME/T ≤ 10μM	0	0	0	0

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
PDE4B_HUMAN	Q07343	CHEMBL275	Phosphodiesterase 4B, Human	51
PDE4D_HUMAN	Q08499	CHEMBL288	Phosphodiesterase 4D, Human	51
PDE4A_HUMAN	P27815	CHEMBL254	Phosphodiesterase 4A, Human	48
PDE4C_HUMAN	Q08493	CHEMBL291	Phosphodiesterase 4C, Human	48
Z50587	Z50587	CHEMBL372	Homo Sapiens	29
MAPK2_HUMAN	P49137	CHEMBL2208	MAP Kinase-activated Protein Kinase 2, Human	24
Z81247	Z81247	CHEMBL399	HeLa (Cervical Adenocarcinoma Cells)	12
Z80166	Z80166	CHEMBL384	HT-29 (Colon Adenocarcinoma Cells)	10
Z80186	Z80186	CHEMBL385	K562 (Erythroleukemia Cells)	10
Z80224	Z80224	CHEMBL387	MCF7 (Breast Carcinoma Cells)	10
Z80362	Z80362	CHEMBL389	P388 (Lymphoma Cells)	7
Z80874	Z80874	CHEMBL393	CEM (T-cell Leukemia)	7
Z80897	Z80897	CHEMBL614806	H9 (T-lymphoid Cells)	7
Z81072	Z81072	CHEMBL397	Jurkat (Acute Leukemic T-cells)	7
Q72547_9HIV1	Q72547	CHEMBL247	Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1	5
Z100081	Z100081	CHEMBL613107	PBMC (Peripheral Blood Mononuclear Cells)	5
Z50512	Z50512	CHEMBL369	Cavia Porcellus	5
Z50607	Z50607	CHEMBL378	Human Immunodeficiency Virus 1	5
Z80125	Z80125	CHEMBL613508	DU-145 (Prostate Carcinoma)	5
Z80285	Z80285	CHEMBL614177	MOLT-4 (Acute T-lymphoblastic Leukemia Cells)	5
Z80295	Z80295	CHEMBL388	MT4 (Lymphocytes)	5
Z80682	Z80682	CHEMBL392	A549 (Lung Carcinoma Cells)	5
Z80928	Z80928	CHEMBL394	HCT-116 (Colon Carcinoma Cells)	5
CLTR1_HUMAN	Q9Y271	CHEMBL1798	Cysteinyl Leukotriene Receptor 1, Human	4
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	4
Z80076	Z80076	CHEMBL614548	CEM-SS (T-cell Leukemia)	4
Z80433	Z80433	CHEMBL614882	RPMI-8226 (Multiple Myeloma Cells)	4
Z80800	Z80800	CHEMBL614725	MIA PaCa-2 (Pancreatic Carcinoma Cells)	4
Z80871	Z80871	CHEMBL612254	Granta Cell Line	4
Z81164	Z81164	CHEMBL614091	LL Cell Line	4
Z81190	Z81190	CHEMBL614099	NCI-H520	4
Z100489	Z100489	CHEMBL614636	Eosinophils (Eosinophils)	3
Z50592	Z50592	CHEMBL374	Oryctolagus Cuniculus	3
Z50677	Z50677	CHEMBL613758	Human Immunodeficiency Virus	3
Z50737	Z50737	CHEMBL612359	Human Immunodeficiency Virus 3	3
Z80035	Z80035	CHEMBL381	B16 (Melanoma Cells)	3
Z80139	Z80139	CHEMBL613509	G-401	3
Z80156	Z80156	CHEMBL383	HL-60 (Promyeloblast Leukemia Cells)	3
Z80193	Z80193	CHEMBL386	L1210 (Lymphocytic Leukemia Cells)	3
Z80814	Z80814	CHEMBL614153	D3F Cell Line	3
Z80945	Z80945	CHEMBL614735	HEp-2 (Laryngeal Carcinoma Cells)	3
Z81034	Z81034	CHEMBL614004	A2780 (Ovarian Carcinoma Cells)	3
Z81252	Z81252	CHEMBL400	MDA-MB-231 (Breast Adenocarcinoma Cells)	3
CLTR2_HUMAN	Q9NS75	CHEMBL4330	Cysteinyl Leukotriene Receptor 2, Human	2
Z50594	Z50594	CHEMBL375	Mus Musculus	2
Z80211	Z80211	CHEMBL614721	LoVo (Colon Adenocarcinoma Cells)	2
Z80244	Z80244	CHEMBL614335	MDA-MB-468 (Breast Adenocarcinoma)	2
Z80294	Z80294	CHEMBL614184	MT2 (Lymphocytes)	2
Z80390	Z80390	CHEMBL390	PC-3 (Prostate Carcinoma Cells)	2
Z80414	Z80414	CHEMBL614628	Raji (B-lymphoblastic Cells)	2
Z80437	Z80437	CHEMBL614885	RWLeu4	2
Z80475	Z80475	CHEMBL613834	SK-BR-3 (Breast Adenocarcinoma)	2
Z80852	Z80852	CHEMBL614069	A-431 (Epidermoid Carcinoma Cells)	2
Z81020	Z81020	CHEMBL395	HepG2 (Hepatoblastoma Cells)	2
Z81024	Z81024	CHEMBL396	NCI-H460 (Non-small Cell Lung Carcinoma)	2
Z81115	Z81115	CHEMBL398	KB (Squamous Cell Carcinoma)	2
Z81169	Z81169	CHEMBL614095	LMM3 Cell Line	2
Z81283	Z81283	CHEMBL614387	NCI-H522 (Non-small Cell Lung Carcinoma Cells)	2
Z81338	Z81338	CHEMBL614309	T-cells	2
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	1
CXCR4_HUMAN	P61073	CHEMBL2107	C-X-C Chemokine Receptor Type 4, Human	1
LT4R1_HUMAN	Q15722	CHEMBL3911	Leukotriene B4 Receptor 1, Human	1
Q862F3_BOVIN	Q862F3	CHEMBL4262	Tubulin Alpha Chain, Bovin	1
Q862L2_BOVIN	Q862L2	CHEMBL3752	Tubulin Alpha-1 Chain, Bovin	1
TBA1A_PIG	P02550	CHEMBL3658	Tubulin Alpha Chain, Pig	1
TBA1A_RAT	P68370	CHEMBL4139	Tubulin Alpha-1 Chain, Rat	1
TBA4A_HUMAN	P68366	CHEMBL2070	Tubulin Alpha-1 Chain, Human	1
TBB1_HUMAN	Q9H4B7	CHEMBL1915	Tubulin Beta-1 Chain, Human	1
TBB2B_BOVIN	Q6B856	CHEMBL3394	Tubulin Beta Chain, Bovin	1
TBB3_HUMAN	Q13509	CHEMBL2597	Tubulin Beta-3 Chain, Human	1
TBB4A_HUMAN	P04350	CHEMBL3838	Tubulin Beta-4 Chain, Human	1
TBB4B_HUMAN	P68371	CHEMBL1848	Tubulin Beta-2 Chain, Human	1
TBB5_HUMAN	P07437	CHEMBL5444	Tubulin Beta-5 Chain, Human	1
TBB8_HUMAN	Q3ZCM7	CHEMBL4024	Tubulin Beta-8 Chain, Human	1
VDR_HUMAN	P11473	CHEMBL1977	Vitamin D Receptor, Human	1
Z100709	Z100709	CHEMBL613821	Squirrel Monkey	1
Z101682	Z101682	CHEMBL613915	BK Polyomavirus	1
Z102020	Z102020	CHEMBL613016	Porcine Endogenous Retrovirus	1
Z103203	Z103203	CHEMBL1075388	A375	1
Z103205	Z103205	CHEMBL1075390	A431	1
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	1
Z50459	Z50459	CHEMBL367	Leishmania Donovani	1
Z50590	Z50590	CHEMBL613488	Sus Scrofa	1
Z50609	Z50609	CHEMBL613499	Simian Immunodeficiency Virus	1
Z50658	Z50658	CHEMBL380	Human Immunodeficiency Virus 2	1
Z50664	Z50664	CHEMBL613748	Rauscher Murine Leukemia Virus	1
Z80002	Z80002	CHEMBL614075	1A9 (Ovarian Adenocarcinoma Cells)	1
Z80018	Z80018	CHEMBL613859	A-375 (Malignant Melanoma Cells)	1
Z80024	Z80024	CHEMBL614518	A9 (Fibroblast Cells)	1
Z80025	Z80025	CHEMBL614519	ACHN (Renal Adenocarcinoma Cells)	1
Z80052	Z80052	CHEMBL614533	C8166 (Leukemic T-cells)	1
Z80071	Z80071	CHEMBL614028	CEM-0 (T-cell Leukemia)	1
Z80073	Z80073	CHEMBL614545	CEM-c113	1
Z80088	Z80088	CHEMBL613853	CHO (Ovarian Cells)	1
Z80096	Z80096	CHEMBL614559	CHO-TAX 5-6	1
Z80097	Z80097	CHEMBL614560	CHO-VV 3-2	1
Z80100	Z80100	CHEMBL614257	COLO 320 (Colon Adenocarcinoma Cells)	1
Z80120	Z80120	CHEMBL614285	DLD-1 (Colon Adenocarcinoma Cells)	1
Z80164	Z80164	CHEMBL614580	HT-1080 (Fibrosarcoma Cells)	1
Z80269	Z80269	CHEMBL614354	MKN-45 (Gastric Adenocarcinoma Cells)	1
Z80354	Z80354	CHEMBL614213	OVCAR-3 (Ovarian Adenocarcinoma Cells)	1
Z80384	Z80384	CHEMBL614233	PBL (Peripheral Blood Lymphocytes)	1
Z80415	Z80415	CHEMBL614629	Ramos (Burkitts Lymhoma B-cells)	1
Z80421	Z80421	CHEMBL614144	RD (Rhabdomyosarcoma Cells)	1
Z80427	Z80427	CHEMBL614879	RKO (Colon Carcinoma)	1
Z80461	Z80461	CHEMBL614903	SCL-1	1
Z80466	Z80466	CHEMBL614907	SF268	1
Z80493	Z80493	CHEMBL614925	SK-OV-3 (Ovarian Carcinoma Cells)	1
Z80516	Z80516	CHEMBL614940	SUP-T1	1
Z80526	Z80526	CHEMBL612544	SW480 (Colon Adenocarcinoma Cells)	1
Z80583	Z80583	CHEMBL391	Vero (Kidney Cells)	1
Z80608	Z80608	CHEMBL614393	ZR-75-1 (Breast Carcinoma Cells)	1
Z80662	Z80662	CHEMBL614259	AA5	1
Z80683	Z80683	CHEMBL614272	ATH8 Cell Line	1
Z80688	Z80688	CHEMBL614797	B(EBV+) Cell Line	1
Z80711	Z80711	CHEMBL613829	NCI/ADR-RES (Breast Carcinoma Cells)	1
Z80712	Z80712	CHEMBL614361	T47D (Breast Carcinoma Cells)	1
Z80720	Z80720	CHEMBL614365	Burkitts Lymphoma Cells	1
Z80721	Z80721	CHEMBL614366	BxT Cell Line	1
Z80737	Z80737	CHEMBL614372	C3H/3T3 (Embryonic Fibroblast Cells)	1
Z80760	Z80760	CHEMBL614779	CFU-GM Cell Line	1
Z80819	Z80819	CHEMBL614484	J774.2	1
Z80901	Z80901	CHEMBL614392	HaCaT (Keratinocytes)	1
Z81054	Z81054	CHEMBL613977	SF-268 (Glioblastoma Cells)	1
Z81057	Z81057	CHEMBL613979	HUVEC (Umbilical Vein Endothelial Cells)	1
Z81117	Z81117	CHEMBL613995	Keratinocytes (Keratinocytes)	1
Z81160	Z81160	CHEMBL614088	Lewis Lung Carcinoma Cell Line	1
Z81170	Z81170	CHEMBL612518	LNCaP (Prostate Carcinoma)	1
Z81223	Z81223	CHEMBL614115	M Cell Line	1
Z81244	Z81244	CHEMBL614123	J774 (Macrophage Cells)	1
Z81245	Z81245	CHEMBL614697	MDA-MB-435 (Breast Carcinoma Cells)	1
Z81280	Z81280	CHEMBL614740	NCI-H226 (Non-small Cell Lung Carcinoma Cells)	1
Z81281	Z81281	CHEMBL614997	NCI-H23 (Non-small Cell Lung Carcinoma Cells)	1
Z81298	Z81298	CHEMBL614846	PE Cell Line	1
Z81331	Z81331	CHEMBL612262	SW-620 (Colon Adenocarcinoma Cells)	1
Z81335	Z81335	CHEMBL612263	HCT-15 (Colon Adenocarcinoma Cells)	1