UCSF

Leukotriene B4 Receptor 1, Human (714 Compounds)

Swissprot:
LT4R1_HUMAN
Stitch:
LT4R1_HUMAN
UniProt:
Q15722
ChEMBL:
CHEMBL3911
Reactome:
REACT_18283
REACT_18302
PDB:
LTB4R

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 714 10 13 8
Binding ≤ 1μM 591 10 13 8
Functional ≤ 10μM 212 2 2 1

Reactome Network (2)

Reactome ID Description Species
REACT_18283 G alpha (q) signalling events Homo sapiens
REACT_18302 Leukotriene receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
CLTR1_HUMAN Q9Y271 CHEMBL1798 Cysteinyl Leukotriene Receptor 1, Human 2
CLTR2_HUMAN Q9NS75 CHEMBL4330 Cysteinyl Leukotriene Receptor 2, Human 63
LT4R2_HUMAN Q9NPC1 CHEMBL3191 Leukotriene B4 Receptor 2, Human 311

Leukotriene receptors

Uniprot Swissprot Chembl Description Number Shared
CLTR1_HUMAN Q9Y271 CHEMBL1798 Cysteinyl Leukotriene Receptor 1, Human 2
CLTR2_HUMAN Q9NS75 CHEMBL4330 Cysteinyl Leukotriene Receptor 2, Human 63
LT4R2_HUMAN Q9NPC1 CHEMBL3191 Leukotriene B4 Receptor 2, Human 311
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
LT4R1_MOUSE O88855 CHEMBL2657 Leukotriene B4 Receptor 1, Mouse 1 0 0 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
LT4R2_HUMAN Q9NPC1 CHEMBL3191 Leukotriene B4 Receptor 2, Human 275 3 4 3

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
LT4R1-1-E Leukotriene B4 Receptor 1 (cluster #1 Of 2), Eukaryotic 686 9 12 9
LT4R1-2-E Leukotriene B4 Receptor 1 (cluster #2 Of 2), Eukaryotic 59 2 1 0
Uniprot Swissprot Chembl Description Number Shared
LT4R2_HUMAN Q9NPC1 CHEMBL3191 Leukotriene B4 Receptor 2, Human 311
CLTR2_HUMAN Q9NS75 CHEMBL4330 Cysteinyl Leukotriene Receptor 2, Human 63
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase, Rat 48
Z50587 Z50587 CHEMBL372 Homo Sapiens 41
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 8
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 5
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 3
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 3
LOX12_HUMAN P18054 CHEMBL3687 Arachidonate 12-lipoxygenase, Human 3
LOX15_HUMAN P16050 CHEMBL2903 Arachidonate 15-lipoxygenase, Human 3
LOX15_RABIT P12530 CHEMBL4358 Arachidonate 15-lipoxygenase, Rabit 3
LOX1_SOYBN P08170 CHEMBL4586 Seed Lipoxygenase-1, Soybn 3
Q9BEG3_BOVIN Q9BEG3 CHEMBL2980 Arachidonate 5-lipoxygenase, Bovin 3
THAS_HUMAN P24557 CHEMBL1835 Thromboxane-A Synthase, Human 3
CLTR1_HUMAN Q9Y271 CHEMBL1798 Cysteinyl Leukotriene Receptor 1, Human 2
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 2
LT4R1_MOUSE O88855 CHEMBL2657 Leukotriene B4 Receptor 1, Mouse 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
PGH1_RAT Q63921 CHEMBL4042 Cyclooxygenase-1, Rat 1
PGH1_SHEEP P05979 CHEMBL2949 Cyclooxygenase-1, Sheep 1
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 1
PGH2_RAT P35355 CHEMBL2977 Cyclooxygenase-2, Rat 1
PGH2_SHEEP P79208 CHEMBL4102 Cyclooxygenase-2, Sheep 1
Z50512 Z50512 CHEMBL369 Cavia Porcellus 1
Z80566 Z80566 CHEMBL612794 U-937 (Histiocytic Lymphoma Cells) 1

Most Common Rings