UCSF

Cysteinyl Leukotriene Receptor 2, Human (327 Compounds)

Swissprot:
CLTR2_HUMAN
Stitch:
CLTR2_HUMAN
UniProt:
Q9NS75
ChEMBL:
CHEMBL4330
Reactome:
REACT_18283
REACT_18302
PDB:
CYSLTR2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 327 13 11 11
Binding ≤ 1μM 289 11 8 8
Functional ≤ 10μM 246 8 2 2

Reactome Network (2)

Reactome ID Description Species
REACT_18283 G alpha (q) signalling events Homo sapiens
REACT_18302 Leukotriene receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
CLTR1_HUMAN Q9Y271 CHEMBL1798 Cysteinyl Leukotriene Receptor 1, Human 500
LT4R1_HUMAN Q15722 CHEMBL3911 Leukotriene B4 Receptor 1, Human 63
LT4R2_HUMAN Q9NPC1 CHEMBL3191 Leukotriene B4 Receptor 2, Human 1

Leukotriene receptors

Uniprot Swissprot Chembl Description Number Shared
CLTR1_HUMAN Q9Y271 CHEMBL1798 Cysteinyl Leukotriene Receptor 1, Human 500
LT4R1_HUMAN Q15722 CHEMBL3911 Leukotriene B4 Receptor 1, Human 63
LT4R2_HUMAN Q9NPC1 CHEMBL3191 Leukotriene B4 Receptor 2, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CLTR1_HUMAN Q9Y271 CHEMBL1798 Cysteinyl Leukotriene Receptor 1, Human 713 18 13 12

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CLTR1_HUMAN Q9Y271 CHEMBL1798 Cysteinyl Leukotriene Receptor 1, Human 500
LT4R1_HUMAN Q15722 CHEMBL3911 Leukotriene B4 Receptor 1, Human 63
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase, Rat 45
Z50512 Z50512 CHEMBL369 Cavia Porcellus 38
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 5
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 3
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 3
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 2
MRP2_HUMAN Q92887 CHEMBL5748 Canalicular Multispecific Organic Anion Transporter 1, Human 2
PGH1_RAT Q63921 CHEMBL4042 Cyclooxygenase-1, Rat 2
PGH2_RAT P35355 CHEMBL2977 Cyclooxygenase-2, Rat 2
Q864F1_PIG Q864F1 CHEMBL3634 Phosphodiesterase 5, Pig 2
THAS_HUMAN P24557 CHEMBL1835 Thromboxane-A Synthase, Human 2
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 2
Z50587 Z50587 CHEMBL372 Homo Sapiens 2
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
Z80566 Z80566 CHEMBL612794 U-937 (Histiocytic Lymphoma Cells) 2
CYSP_TRYCR P25779 CHEMBL3563 Cruzipain, Trycr 1
LT4R2_HUMAN Q9NPC1 CHEMBL3191 Leukotriene B4 Receptor 2, Human 1
PGH1_SHEEP P05979 CHEMBL2949 Cyclooxygenase-1, Sheep 1
PGH2_SHEEP P79208 CHEMBL4102 Cyclooxygenase-2, Sheep 1

Most Common Rings