ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (284)
Reactome (0)
Related By:
Pathway (0)
Organism (5)
Gene (1)
Org. Clust. (7)
ChEMBL (65)
Rings (14)

Cyclooxygenase-2, Sheep (284 Compounds)

Swissprot:: PGH2_SHEEP
Stitch:: PGH2_SHEEP
UniProt:: P79208
ChEMBL:: CHEMBL4102
PDB:: PTGS2

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	284	34	17	15
Binding ≤ 1μM	159	15	5	4
Functional ≤ 10μM	21	3	4	5

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
PGH2_BOVIN	O62698	CHEMBL3331	Cyclooxygenase-2, Bovin	90	15	11	11
PGH2_HUMAN	P35354	CHEMBL230	Cyclooxygenase-2, Human	2,153	141	77	52
PGH2_MOUSE	Q05769	CHEMBL4321	Cyclooxygenase-2, Mouse	250	33	15	9
PGH2_RABIT	O02768	CHEMBL1293198	Prostaglandin G/H Synthase 2, Rabit	10	2	2	1
PGH2_RAT	P35355	CHEMBL2977	Cyclooxygenase-2, Rat	279	32	18	16

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
PGH1_SHEEP	P05979	CHEMBL2949	Cyclooxygenase-1, Sheep	198	36	21	23

Clustered By Gene (0)

Clustered By Organism (7)

Code	Description	Substances	Purchasable	Natural	In Man
PGH2-1-E	Cyclooxygenase-2 (cluster #1 Of 8), Eukaryotic	896	75	38	27
PGH2-2-E	Cyclooxygenase-2 (cluster #2 Of 8), Eukaryotic	35	6	4	1
PGH2-3-E	Cyclooxygenase-2 (cluster #3 Of 8), Eukaryotic	106	28	14	10
PGH2-4-E	Cyclooxygenase-2 (cluster #4 Of 8), Eukaryotic	1,428	55	26	20
PGH2-5-E	Cyclooxygenase-2 (cluster #5 Of 8), Eukaryotic	2	2	2	0
PGH2-6-E	Cyclooxygenase-2 (cluster #6 Of 8), Eukaryotic	11	8	7	7
PGH2-7-E	Cyclooxygenase-2 (cluster #7 Of 8), Eukaryotic	178	7	10	3
PGH2-8-E	Cyclooxygenase-2 (cluster #8 Of 8), Eukaryotic	290	27	8	8

Uniprot	Swissprot	Chembl	Description	Number Shared
PGH1_SHEEP	P05979	CHEMBL2949	Cyclooxygenase-1, Sheep	79
PGH1_HUMAN	P23219	CHEMBL221	Cyclooxygenase-1, Human	39
LOX1_SOYBN	P08170	CHEMBL4586	Seed Lipoxygenase-1, Soybn	13
PGH2_BOVIN	O62698	CHEMBL3331	Cyclooxygenase-2, Bovin	12
PGH2_HUMAN	P35354	CHEMBL230	Cyclooxygenase-2, Human	12
LOX5_HUMAN	P09917	CHEMBL215	Arachidonate 5-lipoxygenase, Human	9
O49150_SOLTU	O49150	CHEMBL3317	5-lipoxygenase, Soltu	9
PGH1_BOVIN	O62664	CHEMBL2860	Cyclooxygenase-1, Bovin	6
PGH2_MOUSE	Q05769	CHEMBL4321	Cyclooxygenase-2, Mouse	6
PGH2_RAT	P35355	CHEMBL2977	Cyclooxygenase-2, Rat	6
PGH1_RAT	Q63921	CHEMBL4042	Cyclooxygenase-1, Rat	4
IL8_HUMAN	P10145	CHEMBL2157	Interleukin-8, Human	3
LOX5_RAT	P12527	CHEMBL312	Arachidonate 5-lipoxygenase, Rat	3
PGH1_MOUSE	P22437	CHEMBL2649	Cyclooxygenase-1, Mouse	3
ALBU_BOVIN	P02769	CHEMBL3728	Serum Albumin, Bovin	2
CAH12_HUMAN	O43570	CHEMBL3242	Carbonic Anhydrase XII, Human	2
CAH13_HUMAN	Q8N1Q1	CHEMBL3912	Carbonic Anhydrase XIII, Human	2
CAH14_HUMAN	Q9ULX7	CHEMBL3510	Carbonic Anhydrase XIV, Human	2
CAH15_MOUSE	Q99N23	CHEMBL5973	Carbonic Anhydrase 15, Mouse	2
CAH2_HUMAN	P00918	CHEMBL205	Carbonic Anhydrase II, Human	2
CAH4_HUMAN	P22748	CHEMBL3729	Carbonic Anhydrase IV, Human	2
CAH5A_HUMAN	P35218	CHEMBL4789	Carbonic Anhydrase VA, Human	2
CAH5B_HUMAN	Q9Y2D0	CHEMBL3969	Carbonic Anhydrase VB, Human	2
CAH6_HUMAN	P23280	CHEMBL3025	Carbonic Anhydrase VI, Human	2
CAH7_HUMAN	P43166	CHEMBL2326	Carbonic Anhydrase VII, Human	2
CAH9_HUMAN	Q16790	CHEMBL3594	Carbonic Anhydrase IX, Human	2
COX2_SHEEP	O78750	CHEMBL1250404	Cytochrome C Oxidase Subunit 2, Sheep	2
CP19A_HUMAN	P11511	CHEMBL1978	Cytochrome P450 19A1, Human	2
Q8SPQ9_CANFA	Q8SPQ9	CHEMBL4033	Cyclooxygenase-2, Canine	2
S22A6_MOUSE	Q8VC69	CHEMBL5653	Solute Carrier Family 22 Member 6, Mouse	2
S22AK_MOUSE	Q80UJ1	CHEMBL5269	Solute Carrier Family 22 Member 20, Mouse	2
AHR_RABIT	O02747	CHEMBL4725	Aryl Hydrocarbon Receptor, Rabit	1
AK1C3_HUMAN	P42330	CHEMBL4681	Aldo-keto-reductase Family 1 Member C3, Human	1
ALDR_HUMAN	P15121	CHEMBL1900	Aldose Reductase, Human	1
B5SU02_9CNID	B5SU02	CHEMBL1075028	Alpha Carbonic Anhydrase, 9cnid	1
C0IX24_9CNID	C0IX24	CHEMBL1649055	Carbonic Anhydrase, 9cnid	1
CAH1_HUMAN	P00915	CHEMBL261	Carbonic Anhydrase I, Human	1
CAH3_HUMAN	P07451	CHEMBL2885	Carbonic Anhydrase III, Human	1
CAH4_BOVIN	Q95323	CHEMBL281	Carbonic Anhydrase IV, Bovin	1
CAH_METTE	P40881	CHEMBL3932	Carbonic Anhydrase, Mette	1
CAN_YEAST	P53615	CHEMBL5931	Carbonic Anhydrase, Yeast	1
CLTR2_HUMAN	Q9NS75	CHEMBL4330	Cysteinyl Leukotriene Receptor 2, Human	1
CP4AA_RAT	P08516	CHEMBL2681	Cytochrome P450 4A1, Rat	1
CP4AB_HUMAN	Q02928	CHEMBL3978	Cytochrome P450 4A11, Human	1
CP4AE_RAT	P20817	CHEMBL2180	Cytochrome P450 4A3, Rat	1
CP4F2_HUMAN	P78329	CHEMBL3379	Cytochrome P450 4F2, Human	1
CXCR1_HUMAN	P25024	CHEMBL4029	Interleukin-8 Receptor A, Human	1
CYNT_MYCTU	O53573	CHEMBL6068	Carbonic Anhydrase, Myctu	1
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	1
FABPL_RAT	P02692	CHEMBL5738	Fatty Acid-binding Protein, Liver, Rat	1
GPR44_HUMAN	Q9Y5Y4	CHEMBL5071	G Protein-coupled Receptor 44, Human	1
LT4R1_HUMAN	Q15722	CHEMBL3911	Leukotriene B4 Receptor 1, Human	1
MK14_HUMAN	Q16539	CHEMBL260	MAP Kinase P38 Alpha, Human	1
NQO2_HUMAN	P16083	CHEMBL3959	Quinone Reductase 2, Human	1
PTGDS_MOUSE	O09114	CHEMBL4334	Prostaglandin-H2 D-isomerase, Mouse	1
Q5AJ71_CANAL	Q5AJ71	CHEMBL5337	Carbonic Anhydrase, Canal	1
Q8HZR1_CANFA	Q8HZR1	CHEMBL4133	Cyclooxygenase-1, Canine	1
THAS_HUMAN	P24557	CHEMBL1835	Thromboxane-A Synthase, Human	1
Z102213	Z102213	CHEMBL613416	Blood	1
Z50587	Z50587	CHEMBL372	Homo Sapiens	1
Z50594	Z50594	CHEMBL375	Mus Musculus	1
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	1
Z80418	Z80418	CHEMBL612557	RAW264.7 (Monocytic-macrophage Leukemia Cells)	1
Z80548	Z80548	CHEMBL614245	THP-1 (Acute Monocytic Leukemia Cells)	1
Z81267	Z81267	CHEMBL614723	Mononuclear Cell Line	1