ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (1,350)
Reactome (3)
Related By:
Pathway (0)
Organism (2)
Gene (2)
Org. Clust. (15)
ChEMBL (71)
Rings (28)

Carbonic Anhydrase IV, Bovin (1,350 Compounds)

Swissprot:: CAH4_BOVIN
Stitch:: CAH4_BOVIN
UniProt:: Q95323
ChEMBL:: CHEMBL281
Reactome:: REACT_227215; REACT_213179; REACT_210340
PDB:: CA4

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	1,350	130	16	18
Binding ≤ 1μM	1,303	116	13	15
Functional ≤ 10μM	9	8	9	9

Reactome ID	Description	Species
REACT_227215	Erythrocytes take up carbon dioxide and release oxygen	Bos taurus
REACT_213179	Erythrocytes take up oxygen and release carbon dioxide	Bos taurus
REACT_210340	Reversible hydration of carbon dioxide	Bos taurus

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
CAH4_HUMAN	P22748	CHEMBL3729	Carbonic Anhydrase IV, Human	223	84	54	59
CAH4_RAT	P48284	CHEMBL2962	Carbonic Anhydrase IV, Rat	3	2	2	2

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
CAH2_BOVIN	P00921	CHEMBL2283	Carbonic Anhydrase II, Bovin	35	3	2	2
CAH6_BOVIN	P18915	CHEMBL4891	Carbonic Anhydrase VI, Bovin	18	1	1	1

Clustered By Gene (0)

Clustered By Organism (15)

Code	Description	Substances	Purchasable	Natural	In Man
CAH4-1-E	Carbonic Anhydrase IV (cluster #1 Of 16), Eukaryotic	1,087	118	20	25
CAH4-10-E	Carbonic Anhydrase IV (cluster #10 Of 16), Eukaryotic	2	0	2	0
CAH4-11-E	Carbonic Anhydrase IV (cluster #11 Of 16), Eukaryotic	4	0	0	0
CAH4-12-E	Carbonic Anhydrase IV (cluster #12 Of 16), Eukaryotic	292	20	3	6
CAH4-13-E	Carbonic Anhydrase IV (cluster #13 Of 16), Eukaryotic	0	0	0	0
CAH4-14-E	Carbonic Anhydrase IV (cluster #14 Of 16), Eukaryotic	19	10	5	5
CAH4-15-E	Carbonic Anhydrase IV (cluster #15 Of 16), Eukaryotic	47	0	0	0
CAH4-16-E	Carbonic Anhydrase IV (cluster #16 Of 16), Eukaryotic	11	7	1	0
CAH4-2-E	Carbonic Anhydrase IV (cluster #2 Of 16), Eukaryotic	4	3	2	2
CAH4-3-E	Carbonic Anhydrase IV (cluster #3 Of 16), Eukaryotic	24	15	13	13
CAH4-4-E	Carbonic Anhydrase IV (cluster #4 Of 16), Eukaryotic	2	2	0	0
CAH4-5-E	Carbonic Anhydrase IV (cluster #5 Of 16), Eukaryotic	7	6	4	4
CAH4-6-E	Carbonic Anhydrase IV (cluster #6 Of 16), Eukaryotic	5	3	5	5
CAH4-7-E	Carbonic Anhydrase IV (cluster #7 Of 16), Eukaryotic	7	1	1	1
CAH4-8-E	Carbonic Anhydrase IV (cluster #8 Of 16), Eukaryotic	2	2	2	1
CAH4-9-E	Carbonic Anhydrase IV (cluster #9 Of 16), Eukaryotic	0	0	0	0

Uniprot	Swissprot	Chembl	Description	Number Shared
CAH2_HUMAN	P00918	CHEMBL205	Carbonic Anhydrase II, Human	1334
CAH1_HUMAN	P00915	CHEMBL261	Carbonic Anhydrase I, Human	1145
CAH9_HUMAN	Q16790	CHEMBL3594	Carbonic Anhydrase IX, Human	170
CAH4_HUMAN	P22748	CHEMBL3729	Carbonic Anhydrase IV, Human	63
CAH12_HUMAN	O43570	CHEMBL3242	Carbonic Anhydrase XII, Human	62
MMP9_HUMAN	P14780	CHEMBL321	Matrix Metalloproteinase 9, Human	52
MMP2_HUMAN	P08253	CHEMBL333	Matrix Metalloproteinase-2, Human	51
MMP8_HUMAN	P22894	CHEMBL4588	Matrix Metalloproteinase 8, Human	51
MMP13_HUMAN	P45452	CHEMBL280	Matrix Metalloproteinase 13, Human	50
MMP1_HUMAN	P03956	CHEMBL332	Matrix Metalloproteinase-1, Human	50
CAH5A_MOUSE	P23589	CHEMBL2330	Carbonic Anhydrase VA, Mouse	46
CAH5B_MOUSE	Q9QZA0	CHEMBL4634	Carbonic Anhydrase VB, Mouse	46
CAH7_HUMAN	P43166	CHEMBL2326	Carbonic Anhydrase VII, Human	38
CAH14_HUMAN	Q9ULX7	CHEMBL3510	Carbonic Anhydrase XIV, Human	37
CAH6_HUMAN	P23280	CHEMBL3025	Carbonic Anhydrase VI, Human	37
CAH15_MOUSE	Q99N23	CHEMBL5973	Carbonic Anhydrase 15, Mouse	35
CAH5B_HUMAN	Q9Y2D0	CHEMBL3969	Carbonic Anhydrase VB, Human	34
B5SU02_9CNID	B5SU02	CHEMBL1075028	Alpha Carbonic Anhydrase, 9cnid	31
C0IX24_9CNID	C0IX24	CHEMBL1649055	Carbonic Anhydrase, 9cnid	31
CAH5A_HUMAN	P35218	CHEMBL4789	Carbonic Anhydrase VA, Human	31
CYNT_HELPY	O24855	CHEMBL4211	Carbonic Anhydrase 1, Helpy	31
Q5AJ71_CANAL	Q5AJ71	CHEMBL5337	Carbonic Anhydrase, Canal	31
CAN_YEAST	P53615	CHEMBL5931	Carbonic Anhydrase, Yeast	29
Y1284_MYCTU	P64797	CHEMBL5631	Uncharacterized Protein Rv1284/MT1322, Myctu	28
CAH13_MOUSE	Q9D6N1	CHEMBL2186	Carbonic Anhydrase XIII, Mouse	20
CAH_METTE	P40881	CHEMBL3932	Carbonic Anhydrase, Mette	20
CAH2_BOVIN	P00921	CHEMBL2283	Carbonic Anhydrase II, Bovin	19
CAH6_BOVIN	P18915	CHEMBL4891	Carbonic Anhydrase VI, Bovin	18
CYNT_MYCTU	O53573	CHEMBL6068	Carbonic Anhydrase, Myctu	18
P96878_MYCTU	P96878	CHEMBL5767	PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE), Myctu	15
CAH13_HUMAN	Q8N1Q1	CHEMBL3912	Carbonic Anhydrase XIII, Human	11
MMP3_HUMAN	P08254	CHEMBL283	Matrix Metalloproteinase 3, Human	8
CAH3_HUMAN	P07451	CHEMBL2885	Carbonic Anhydrase III, Human	7
MMP12_MOUSE	P34960	CHEMBL2594	Matrix Metalloproteinase 12, Mouse	5
Q3I4V7_CRYNV	Q3I4V7	CHEMBL1697676	Carbonic Anhydrase 2, Crynv	3
CAH10_HUMAN	Q9NS85	CHEMBL4645	Carbonic Anhydrase-related Protein 10, Human	2
CAH11_HUMAN	O75493	CHEMBL2420	Carbonic Anhydrase-related Protein 2, Human	2
CAH2_RAT	P27139	CHEMBL4706	Carbonic Anhydrase II, Rat	2
CAH3_RAT	P14141	CHEMBL4997	Carbonic Anhydrase III, Rat	2
CAH4_RAT	P48284	CHEMBL2962	Carbonic Anhydrase IV, Rat	2
CAH5A_RAT	P43165	CHEMBL2138	Carbonic Anhydrase VA, Rat	2
CAH8_HUMAN	P35219	CHEMBL2410	Carbonic Anhydrase-related Protein 8, Human	2
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	2
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	2
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	2
PGH2_HUMAN	P35354	CHEMBL230	Cyclooxygenase-2, Human	2
Z50587	Z50587	CHEMBL372	Homo Sapiens	2
ADA17_HUMAN	P78536	CHEMBL3706	ADAM17, Human	1
CAH7_MOUSE	Q9ERQ8	CHEMBL2216	Carbonic Anhydrase VII, Mouse	1
COX2_HUMAN	P00403	CHEMBL6174	Cytochrome C Oxidase Subunit 2, Human	1
COX2_SHEEP	O78750	CHEMBL1250404	Cytochrome C Oxidase Subunit 2, Sheep	1
LEF_BACAN	P15917	CHEMBL4372	Anthrax Lethal Factor, Bacan	1
MK14_HUMAN	Q16539	CHEMBL260	MAP Kinase P38 Alpha, Human	1
MMP14_HUMAN	P50281	CHEMBL3869	Matrix Metalloproteinase 14, Human	1
PGH1_BOVIN	O62664	CHEMBL2860	Cyclooxygenase-1, Bovin	1
PGH1_HUMAN	P23219	CHEMBL221	Cyclooxygenase-1, Human	1
PGH1_MOUSE	P22437	CHEMBL2649	Cyclooxygenase-1, Mouse	1
PGH1_SHEEP	P05979	CHEMBL2949	Cyclooxygenase-1, Sheep	1
PGH2_BOVIN	O62698	CHEMBL3331	Cyclooxygenase-2, Bovin	1
PGH2_MOUSE	Q05769	CHEMBL4321	Cyclooxygenase-2, Mouse	1
PGH2_RAT	P35355	CHEMBL2977	Cyclooxygenase-2, Rat	1
PGH2_SHEEP	P79208	CHEMBL4102	Cyclooxygenase-2, Sheep	1
Q2PCB5_DICLA	Q2PCB5	CHEMBL1795125	Carbonic Anhydrase, Dicla	1
Q50565_METTH	Q50565	CHEMBL3926	Carbonic Anhydrase, Metth	1
Q6FTL6_CANGA	Q6FTL6	CHEMBL6185	Carbonic Anhydrase, Canga	1
Q8HZR1_CANFA	Q8HZR1	CHEMBL4133	Cyclooxygenase-1, Canine	1
Q8SPQ9_CANFA	Q8SPQ9	CHEMBL4033	Cyclooxygenase-2, Canine	1
Z100741	Z100741	CHEMBL614867	MC9 (Mast Cells)	1
Z80362	Z80362	CHEMBL389	P388 (Lymphoma Cells)	1
Z80548	Z80548	CHEMBL614245	THP-1 (Acute Monocytic Leukemia Cells)	1
Z80928	Z80928	CHEMBL394	HCT-116 (Colon Carcinoma Cells)	1