Anthrax Lethal Factor, Bacan (193 Compounds)


Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 193 34 7 7
Binding ≤ 1μM 108 8 0 1

Reactome Network (1)

Reactome ID Description Species
REACT_228255 Uptake and function of anthrax toxins Homo sapiens

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
LEF-1-B Anthrax Lethal Factor (cluster #1 Of 2), Bacterial 174 25 4 6
LEF-2-B Anthrax Lethal Factor (cluster #2 Of 2), Bacterial 19 9 3 1
Uniprot Swissprot Chembl Description Number Shared
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 3
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 3
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 3
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 3
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 3
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 2
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 2
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 2
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 2
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 2
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 2
Q9AQH7_STAAU Q9AQH7 CHEMBL5643 DnaC Helicase, Staau 2
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 2
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 2
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 2
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 2
ADA10_HUMAN O14672 CHEMBL5028 ADAM10, Human 1
BMP1_HUMAN P13497 CHEMBL3898 Bone Morphogenetic Protein 1, Human 1
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 1
CAH4_BOVIN Q95323 CHEMBL281 Carbonic Anhydrase IV, Bovin 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
CETP_HUMAN P11597 CHEMBL3572 Cholesteryl Ester Transfer Protein, Human 1
CYSP_TRYCR P25779 CHEMBL3563 Cruzipain, Trycr 1
DUS3_HUMAN P51452 CHEMBL2635 Dual Specificity Protein Phosphatase 3, Human 1
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 1
ELNE_HUMAN P08246 CHEMBL248 Leukocyte Elastase, Human 1
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 1
FDFT_HUMAN P37268 CHEMBL3338 Squalene Synthetase, Human 1
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 1
KLKB1_HUMAN P03952 CHEMBL2000 Plasma Kallikrein, Human 1
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 1
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 1
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 1
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 1
KPCI_HUMAN P41743 CHEMBL2598 Protein Kinase C Iota, Human 1
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 1
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 1
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
MMP12_MOUSE P34960 CHEMBL2594 Matrix Metalloproteinase 12, Mouse 1
MMP13_RAT P23097 CHEMBL4944 Matrix Metalloproteinase 13, Rat 1
MMP16_HUMAN P51512 CHEMBL2200 Matrix Metalloproteinase 16, Human 1
MMP25_HUMAN Q9NPA2 CHEMBL1795103 Matrix Metalloproteinase-25, Human 1
MMP2_MOUSE P33434 CHEMBL3095 Matrix Metalloproteinase-2, Mouse 1
MMP7_HUMAN P09237 CHEMBL4073 Matrix Metalloproteinase 7, Human 1
MMP9_MOUSE P41245 CHEMBL2214 Matrix Metalloproteinase 9, Mouse 1
NEP_HUMAN P08473 CHEMBL1944 Neprilysin, Human 1
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 1
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1
SIRT2_HUMAN Q8IXJ6 CHEMBL4462 NAD-dependent Deacetylase Sirtuin 2, Human 1
THA_HUMAN P10827 CHEMBL1860 Thyroid Hormone Receptor Alpha, Human 1
THB_HUMAN P10828 CHEMBL1947 Thyroid Hormone Receptor Beta-1, Human 1
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 1