UCSF

Matrix Metalloproteinase 16, Human (61 Compounds)

Swissprot:
MMP16_HUMAN
Stitch:
MMP16_HUMAN
UniProt:
P51512
ChEMBL:
CHEMBL2200
Reactome:
REACT_118682
PDB:
1RM8 (DOCK)
MMP16

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 61 3 1 4
Binding ≤ 1μM 42 3 1 3

Reactome Network (1)

Reactome ID Description Species
REACT_118682 Activation of Matrix Metalloproteinases Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
MMP10_HUMAN P09238 CHEMBL4270 Matrix Metalloproteinase 10, Human 2
MMP11_HUMAN P24347 CHEMBL2867 Matrix Metalloproteinase 11, Human 1
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 34
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 53
MMP15_HUMAN P51511 CHEMBL2963 Matrix Metalloproteinase 15, Human 29
MMP17_HUMAN Q9ULZ9 CHEMBL2937 Matrix Metalloproteinase 17, Human 1
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 33
MMP25_HUMAN Q9NPA2 CHEMBL1795103 Matrix Metalloproteinase-25, Human 1
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 60
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 20
MMP7_HUMAN P09237 CHEMBL4073 Matrix Metalloproteinase 7, Human 12
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 35
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 55
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
MMP10_HUMAN P09238 CHEMBL4270 Matrix Metalloproteinase 10, Human 82 1 1 1
MMP11_HUMAN P24347 CHEMBL2867 Matrix Metalloproteinase 11, Human 71 1 1 1
MMP12_HUMAN P39900 CHEMBL4393 Matrix Metalloproteinase 12, Human 289 8 4 5
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 2,513 43 6 37
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 507 9 8 14
MMP15_HUMAN P51511 CHEMBL2963 Matrix Metalloproteinase 15, Human 30 1 1 3
MMP17_HUMAN Q9ULZ9 CHEMBL2937 Matrix Metalloproteinase 17, Human 29 1 1 1
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 2,665 22 9 44
MMP25_HUMAN Q9NPA2 CHEMBL1795103 Matrix Metalloproteinase-25, Human 8 0 0 1
MMP26_HUMAN Q9NRE1 CHEMBL4707 Matrix Metalloproteinase 26, Human 23 1 1 2
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 2,765 37 17 44
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 2,212 22 9 40
MMP7_HUMAN P09237 CHEMBL4073 Matrix Metalloproteinase 7, Human 467 10 4 22
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 980 16 6 25
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 2,243 31 11 34

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 60
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 55
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 53
MMP12_HUMAN P39900 CHEMBL4393 Matrix Metalloproteinase 12, Human 46
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 35
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 34
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 33
MMP15_HUMAN P51511 CHEMBL2963 Matrix Metalloproteinase 15, Human 29
MMP26_HUMAN Q9NRE1 CHEMBL4707 Matrix Metalloproteinase 26, Human 23
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 20
MMP7_HUMAN P09237 CHEMBL4073 Matrix Metalloproteinase 7, Human 12
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 5
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 5
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 5
ADA17_PIG O77636 CHEMBL3332 ADAM17, Pig 4
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 4
ADA10_HUMAN O14672 CHEMBL5028 ADAM10, Human 2
MMP10_HUMAN P09238 CHEMBL4270 Matrix Metalloproteinase 10, Human 2
ADA12_HUMAN O43184 CHEMBL5030 ADAM12, Human 1
ADA33_HUMAN Q9BZ11 CHEMBL6121 Disintegrin And Metalloproteinase Domain-containing Protein 33, Human 1
ADAM9_HUMAN Q13443 CHEMBL5982 ADAM9, Human 1
BMP1_HUMAN P13497 CHEMBL3898 Bone Morphogenetic Protein 1, Human 1
LEF_BACAN P15917 CHEMBL4372 Anthrax Lethal Factor, Bacan 1
MMP11_HUMAN P24347 CHEMBL2867 Matrix Metalloproteinase 11, Human 1
MMP12_MOUSE P34960 CHEMBL2594 Matrix Metalloproteinase 12, Mouse 1
MMP13_RAT P23097 CHEMBL4944 Matrix Metalloproteinase 13, Rat 1
MMP17_HUMAN Q9ULZ9 CHEMBL2937 Matrix Metalloproteinase 17, Human 1
MMP25_HUMAN Q9NPA2 CHEMBL1795103 Matrix Metalloproteinase-25, Human 1
MMP2_MOUSE P33434 CHEMBL3095 Matrix Metalloproteinase-2, Mouse 1
MMP9_MOUSE P41245 CHEMBL2214 Matrix Metalloproteinase 9, Mouse 1
TNFA_HUMAN P01375 CHEMBL1825 TNF-alpha, Human 1